Roadmap on specialty optical fibers by Mário F S Ferreira, Mohd Rehan, Vishwatosh Mishra, Shailendra Kumar Varshney, Francesco Poletti, Nguyen Phuoc Trung Hoa, Weichao Wang, Qinyuan Zhang, Wenyu Du, Benli Yu, Zhijia Hu, Xian Feng, Jindan Shi, Anjali, Sunil Kumar, Michal Kamrádek, Mukul Chandra Paul, Kazi Abedin, Bertrand Kibler, Frédéric Smektala, Xiushan Zhu, Andrey Pryamikov, Stephan Reitzenstein

“…This roadmap on specialty optical fibers addresses different technologies and application areas. It is constituted by fourteen contributions authored by world-leading experts, providing insight into the current state-of-the-art and the challenges their respective fields face. …”
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Molecular Characterization and Evolution Analysis of Two Forms of TLR5 and TLR13 Genes Base on Larimichthys crocea Genome Data by Lihua Jiang, Liyi Pei, Ping Wang, Liqin Liu, Gong Li, Binjian Liu, Zhenming Lǚ, Tabata Hiromasa, Hao Pan, Atsushi Ogura

“…These TLRs share high sequence homology with other ichthyic TLRs, while also having their own characters; qtPCR was determined and the results found that the three genes were constitutively expressed in all examined tissues: TLR5M was highly expressed in the spleen and liver; TLR13 expression was high in the kidney, liver, and spleen. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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A Novel Method to Evaluate the Effect of Slope Blasting under Impact Loading by Wenhai Zhou, Zhenbao Li, Xin Wu, Shujiang Wang, Yaru Lv, Xiaoming Lou, Chaofei Du, Rui Liang

“…And the numerical model of slope blasting is established by embedding the evolution relationship of tensile and compressive damage into the elastoplastic constitutive material. The evaluation method proposed in this paper is used to evaluate the postexplosion effect of Zijin Mountain gold-copper mine slope cast blasting. …”
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Effects of Different Ratios of Fly Ash and River Sand on Mechanical Properties of Cemented Paste Backfill Materials by Jiang Li, Shenggen Cao, Yang Liu, Chiyuan Che, Changzheng Zhao, Shuyu Du, Kaifei Wang, Ruiting Ma

“…Based on Weibull distribution and prepeak correction factor, a damage constitutive model was established to describe the stress–strain process of CPB under load. …”
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Barriers to Occupational Health and Safety Legal Services During Pandemic by Arjun Aryal, Ava Shrestha, Yadav Prasad Joshi

“…Despite the legal provisions in the current constitution, acts, and rules, the access of marginalised populations like workers to OHS services is challenged. …”
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Increased Expression of VEGF and CD31 in Postradiation Rectal Tissue: Implications for Radiation Proctitis by G. Karamanolis, I. Delladetsima, V. Kouloulias, K. Papaxoinis, I. Panayiotides, D. Haldeopoulos, K. Triantafyllou, N. Kelekis, S. D. Ladas

“…Our results showed that in postradiation rectal biopsy specimens neoangiogenesis seems to be inflammation-related and constitutes a significant postradiation component of the tissue injury.…”
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A review on bioremediation by microbial immobilization-an effective alternative for wastewater treatment by Frank Abimbola Ogundolie, Olorunfemi Oyewole Babalola, Charles Oluwaseun Adetunji, Christiana Eleojo Aruwa, Jacqueline Njikam Manjia, Taoheed Kolawole Muftaudeen

“…Bioremediation involving the use of microbial cell immobilization has demonstrated enhanced effectiveness compared to free cells. This constitutes a significant departure from traditional bioremediation practices (entrapment, adsorption, encapsulation), in addition to its ability to engage in covalent bonding and cross-linking. …”
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Meta-analysis of the clinical efficacy of liraglutide in treating type 2 diabetes mellitus complicated with non-alcoholic fatty liver disease by Yuan-Yuan Xu, Xu Wang, Yu-Qing She, Jie Liu, Qing Zhang

“…., insulin), liraglutide may improve glucose metabolism, lipid and liver function parameters, and visceral and subcutaneous fat in patients with T2DM and NAFLD, thus constituting an effective treatment for these patients.…”
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C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability by Santhosh Kumar Nagarajan, Joy Weber, Daniel Roderer, Jörg Piontek

“…We propose that this claudin ring constitutes an anchor for a twisting mechanism that drives extension and membrane insertion of the CPE β-hairpins. …”
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Histopathological Study of Skin Adnexal Tumours—Institutional Study in South India by Ankit Sharma, Deepak G. Paricharak, Jitendra Singh Nigam, Shivani Rewri, Priyanka Bhatia Soni, Anita Omhare, Preethi Sekar

“…The sweat gland tumors constituted the largest group (42.86% 24/56) cases followed by the hair follicle tumors (35.71%, 20/56) of cases and sebaceous gland tumors (21.43%, 12/56) cases. …”
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Generation of bovine decellularized testicular bio-scaffolds as a 3D platform for testis bioengineering by Francesca Di Filippo, Tiziana A. L. Brevini, Georgia Pennarossa, Fulvio Gandolfi

“…Overall, the generated 3D bio-scaffolds may constitute a suitable artificial niche for ex vivo culture of testicular cells and may represent a possible strategy to reproduce spermatogenesis in vitro.…”
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Development and validation of PCR marker array for molecular selection towards spring, vernalization-independent and winter, vernalization-responsive ecotypes of white lupin (Lupin... by Anna Surma, Michał Książkiewicz, Wojciech Bielski, Bartosz Kozak, Renata Galek, Sandra Rychel-Bielska

“…Three DArT-seq, two silicoDArT and seven LalbFTc1 INDEL markers were positively validated, constituting a convenient PCR-based marker assay for rapid and accurate reselection of white lupin germplasm towards early flowering and thermoneutrality or late flowering and vernalization-responsiveness, as well as for tracking high genetic and phenotypic diversity within white lupin landraces, revealed in the present study.…”
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Food Addiction, Saturated Fat Intake, and Body Mass Index in Peruvian Adults: A Cross-Sectional Survey by Dulce E. Lopez-Lopez, Ivett K. Saavedra-Roman, Yaquelin E. Calizaya-Milla, Jacksaint Saintila

“…Cardiovascular diseases (CVDs) constitute one of the main public health problems and represent a greater risk of mortality and morbidity for the world population. …”
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Knowledge, attitudes, and practices toward leishmaniasis and one health: a cross-sectional study among medical and veterinary professionals by Yasir Khan, I-Chen Lin, Sundus Khan, Mehtab Kanwal, Abdul Wajid, Aamir Khan, Fazal Noor, Ali Madi Almajwal, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdul Qadeer

“…Veterinary professionals (42.1%) and students (27.4%) constituted the primary respondents, with 32.4% working in government hospitals. …”
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Characterization of acute respiratory infections behavior. Cienfuegos Province. First quarter 2020 by Bárbara del Rosario Téllez Cacín, María Lina Valdés Gómez, José Aurelio Díaz Quiñones, Lourdes Elena Duany Badell, Ling Denisse Santeiro Pérez, Sadys Suarez del Villar Seuret

“…<p><strong>Foundation:</strong> due to the current pandemic of COVID 19, it is important to know the categorizing essentialities of acute respiratory infections in general for future studies in which COVID 19 will constitute a category of the taxonomy of those to be taken into account.…”
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Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension by Justin H. Berger, Yuji Shi, Timothy R. Matsuura, Kirill Batmanov, Xian Chen, Kelly Tam, Mackenzie Marshall, Richard Kue, Jiten Patel, Renee Taing, Russell Callaway, Joanna Griffin, Attila Kovacs, Dinesh Hirenallur-Shanthappa, Russell Miller, Bei B. Zhang, Rachel J. Roth Flach, Daniel P. Kelly

“…C57Bl6/NJ mice fed a high-fat diet (HFD) for > 10 weeks were administered an AAV8-driven vector resulting in constitutive overexpression of mouse Renin1d. HFD-Renin (aka “HFpEF”) mice demonstrated obesity and insulin resistance, moderate left ventricular hypertrophy, preserved systolic function, and diastolic dysfunction indicated by echocardiographic measurements; increased left atrial mass; elevated natriuretic peptides; and exercise intolerance. …”
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The landscape of cell regulatory and communication networks in the human dental follicle by Jia-Ning Liu, Jia-Ning Liu, Jiong-Yi Tian, Lu Liu, Lu Liu, Yuan Cao, Yuan Cao, Xiao Lei, Xiao Lei, Xiao-Hui Zhang, Xiao-Hui Zhang, Zi-Qi Zhang, Zi-Qi Zhang, Jun-Xi He, Jun-Xi He, Chen-Xi Zheng, Chao Ma, Sheng-Feng Bai, Bing-Dong Sui, Fang Jin, Ji Chen, Ji Chen

“…However, the specific cellular components and the intricate regulatory mechanisms governing the postnatal development and biological function of the dental follicle have not been completely understood.MethodsWe analyzed dental follicles with single-cell RNA sequencing (scRNA-seq) to reveal their cellular constitution molecular signatures by cell cycle analysis, scenic analysis, gene enrichment analysis, and cell communication analysis.ResultsTen cell clusters were identified with differential characteristics, among which immune and vessel-related cells, as well as a stem cell population, were revealed as the main cell types. …”
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Assessment of the nitrogen fertilizer split-application on maize grain yield and profitability on Nitisols of South-Kivu, Eastern D.R. Congo by Patient M. Zamukulu, Espoir M. Bagula, Jean M. Mondo, Géant B. Chuma, Gisèle M. Bulonza, Sarah Mwaluke, Yannick Mugumaarhahama, Céphas B. Mwimangire, Eloïs L. Cinyabuguma, Antoine K. Lubobo, Gustave N. Mushagalusa

“…Abstract Soil depletion constitutes a major challenge for agriculture and food security in highlands of eastern Democratic Republic of Congo (DRC). …”
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Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis by Shu-Wua Lee, Po-Chung Yu, Ting-Ting Yen, Chiann-Yi Hsu, Li-Jou Lai, I-Chun Chen, Ting-Gang Chang

“…Introduction Approximately 60 million individuals worldwide used opioids in 2021, constituting 1.2% of the global adult population. This study aimed to evaluate the effectiveness of integrated treatment strategies for opioid use disorder and nicotine use disorder by assessing the impact of smoking cessation within a methadone treatment framework. …”
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