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4121
Provide a Framework for the Application of Open Policy Making in Parliament of Iran
Published 2024-03-01“…Grounded theory and Maxqda10 software were used for data analysis in the qualitative part, while the structural equation modeling approach was applied in the quantitative part.ResultsData analysis identified the general dimensions and preconditions of the open policy model, along with the components and elements constituting its main dimensions, including understanding the problem, developing solutions, compiling, and evaluating. …”
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4122
Anti-Methanogenic Potential of Seaweeds and Impact on Feed Fermentation and Rumen Microbiome In Vitro
Published 2025-01-01“…The prevalence of <i>Methanobrevibacter</i> was similar across treatments, constituting the majority (~79%) of the archaeal community. …”
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4123
Legal Disputes of Emigrant Periodical Publishers from the End of the 19th Century to 1904
Published 2024-07-01“…As the role of the press grew within the community, clergy, who constituted the majority of the right-wing leadership, found themselves losing the unchallenged authority they had in Lithuania and were unable to compensate for it through their own press and polemics against other factions. …”
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4124
Designing a model of institutionalization of organizational culture based on synergy in the tourism holding of Parsian Hotels Group
Published 2024-09-01“…The findings showed that all the factors constituting the organizational culture institutionalization model based on synergy in the tourism holding of Parsian Hotels Group (team building, cohesion, structure, innovation, support, motivation, participation and performance) are significant at the 95% confidence level, and as a result, the overall fit of the model GOF was equal to 0.65, which shows the usefulness of the model. …”
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4125
Association of different insulin resistance surrogates with all-cause and cardiovascular mortality among the population with cardiometabolic multimorbidity
Published 2025-01-01“…Conclusions This study emphasizes the prognostic significance of IR surrogates, particularly the TyG index, in predicting mortality among individuals with CMM. The TyG index constitutes a crucial element in the development of management and intervention strategies for these patients. …”
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4126
Targeting deubiquitinase USP7-mediated stabilization of XPO1 contributes to the anti-myeloma effects of selinexor
Published 2025-01-01“…However, intrinsic and acquired drug resistance constitute great challenges. SEL has been reported to promote the degradation of XPO1 protein in tumor cells. …”
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4127
TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate
Published 2025-01-01“…Variant origin was elucidated in 39 of these: 72% patients had a constitutional PV, 10% were mosaics, and 18% had CHIP-associated PVs. …”
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4128
IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice
Published 2025-01-01“…More importantly, we identified twelve critical components of RS1 in humans and mice, among which RSPH3, RSPH6A, RSPH9 and DYDC1 constituting the head, DYDC1, NME5, DNAJB13 and PPIL6 assembling into the head-neck complex, AK8, ROPN1L, RSPH14, DYNLL1, and IQUB forming the stalk of RS1. …”
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4129
Secular trend and projection of overweight and obesity among Chinese children and adolescents aged 7–18 years from 1985 to 2019: Rural areas are becoming the focus of investment
Published 2025-02-01“…We analyzed data from seven rounds of the Chinese National Survey on Students Constitution and Health (CNSSCH) conducted from 1985 to 2019, focusing on school-age children and adolescents aged 7–18 years. …”
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4130
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer
Published 2025-01-01“…Abstract Background Drug resistance constitutes one of the principal causes of poor prognosis in breast cancer patients. …”
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4131
The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet
Published 2023-01-01“…The most productive sites were constituted by exploitative plant species which depleted N resources in the soil, and by microbes producing relatively few extracellular enzymes, leading to a lower PNM. …”
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4132
HIV self-testing positivity rate and linkage to confirmatory testing and care: a telephone survey in Côte d’Ivoire, Mali, and Senegal
Published 2024-06-01“…However, if confirmed HIV-positive, almost all initiated treatment. HIVST constitutes a relevant complementary tool to existing screening services. …”
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4133
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
Published 2021-02-01“…Background Modulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg population, indicating the need for a ti-Treg specific biomarker.Methods We employed single-cell RNA-sequencing in a mouse model of non-small cell lung carcinoma (NSCLC) to obtain a comprehensive overview of the tumor-infiltrating T-cell compartment, with a focus on ti-Treg subpopulations. …”
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4134
Club Cell Protein 16 Attenuates CD16brightCD62dim Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury
Published 2021-01-01“…Since CC16 affects both the distribution of PMNL subsets and apoptosis in tissues after trauma, it may constitute as a novel target to beneficially shape the posttraumatic tissue microenvironment and homeostasis to improving outcomes.…”
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4135
Assessment of out-of-pocket (OOP) expenditures on essential medicines for acute and chronic illness: a comparative study across regional and socioeconomic groups in India
Published 2025-01-01“…Wealthy households constituted most of the OOP expenditure (81 wealthy households), whereas 33 poor households also contributed to the OOP expenditure. …”
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4136
Le français dans la géopolitique méditerranéenne
Published 2021-12-01“…Ce principe s’avère en effet d’autant plus porteur qu’ainsi conçue, la langue française, non certes de par sa nature mais par son histoire, véhicule des valeurs éthiques (qui souvent, comme en témoigne la création lexicale, ont d’abord été désignées et définies en français) et a des moyens d’expression répondant aux besoins de la res publica. Le libellé de la Constitution française est explicite à cet égard – Le français est la langue de la République (non d’un territoire ou de l’État) –, et fait ainsi « référence à un type précis de rapport » (Klinkenberg) entre langue et conception de société. …”
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4137
Genome-wide identification, characterization and expression analysis of WRKY transcription factors under abiotic stresses in Carthamus tinctorius L
Published 2025-01-01“…Abstract Background WRKY transcription factors constitute one of the largest families of plant transcriptional regulators, playing pivotal roles in plant responses to biotic and abiotic stresses, as well as in hormonal signaling and secondary metabolism regulation. …”
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4138
Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii
Published 2025-02-01“…Developing an appropriate animal model will help further study the pathogenesis of CNGM.Methods: Seventy-two rats were randomly assigned to seven groups: group A (n=12, tissue suspension 0.2mL), group B (n=12, 1× 10^8 CFU/mL Corynebacterium kroppenstedtii (CK) suspension 0.1mL), group C (n=12, 1× 10^9 CFU/mL CK suspension 0.1mL), group D (n=12, tissue suspension 0.1mL + 1× 10^8 CFU/mL CK suspension 0.1mL), group E (n=12, tissue suspension 0.1mL + 1× 10^9 CFU/mL CK suspension 0.1mL), group F (n=6, phosphate buffer saline solution 0.1mL), and group G (n=6, physiological saline 0.1mL + Complete Freund’s adjuvant suspension 0.1mL). Groups A to E constitute the experimental groups with 12 rats each, while groups F and G served as control groups with 6 rats each. …”
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4139
Plaider la « bonne gouvernance sécuritaire » au Maroc : Domestiquer les savoirs de réforme en régime de contrainte consensuelle
Published 2024-09-01“…If, on the one hand, this reformist lexicon promotes NGOs’ depoliticized commitment and the institutional construction of a liberal appearance, on the other, it constitutes a tool in the hands of professionalized and internationalized NGOs, which allows them to keep the discussion open with the authorities around the security issue. …”
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4140
Improving the representation of major Indian crops in the Community Land Model version 5.0 (CLM5) using site-scale crop data
Published 2025-02-01“…<p>Accurate representation of croplands is essential for simulating terrestrial water, energy, and carbon fluxes over India because croplands constitute more than 50 % of the Indian land mass. Wheat and rice are the two major crops grown in India, covering more than 80 % of the agricultural land. …”
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