Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance by Roberto Perniola

“…Its related protein, AIRE, activates the transcription of genes encoding for tissue-specific antigens (TsAgs) in a subset of medullary thymic epithelial cells: the presentation of TsAgs to the maturating thymocytes induces the apoptosis of the autoreactive clones and constitutes the main form of central tolerance. Dysregulation of thymic AIRE expression in genetically transmitted and acquired diseases other than APS-1 may contribute to further forms of autoimmunity. …”
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Cytokines and Liver Diseases by Herbert Tilg

“…In most tissues, including the liver, constitutive production of cytokines is absent or minimal. …”
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Alternative Definitions of Complexity for Practical Applications of Model Selection Criteria by Murari Andrea, Riccardo Rossi, Teddy Craciunescu

“…All the upgrades are easy to implement and typically outperform the traditional versions of model selection criteria and constitute a good set of alternatives to be deployed, depending on the priorities of the investigators and the characteristics of the application.…”
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Sociologia na educação básica no Brasil: um balanço da experiência remota e recente by Simone Meucci

“…We find that in both periods, with different meanings, the introduction of sociology in the school was related to a social awareness of crisis and the need for institutional reconstruction, responding to historical demands of the constitution of new social actors.…”
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Les liminalités dans les représentations du cycle solaire quotidien by Danièle Dehouve

“…The transitions of the first type are sunrise and sunset, here called anchoring zones; they correspond to the notion of “thick boundary” developed by Desclés to designate the existence of intermediate spaces between categories; those of the second type are the midday and midnight points, here called pivots because they constitute zones of exchange and shifting between the rising sun and setting sun.…”
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Exú's Work – The Agency of Ritual Objects in Southeast Brazilian Umbanda by Eleonora A. Lundell

“…In people’s experiences of spiritual work (trabalho) and spiritual development (desenvolvimento) carried out with Exús – guardians, guides and protectors who have, after their death, returned in order to work for people’s wellbeing – ritual objects (such as bodies, clothes, beverages, herbs, cigarettes, candles, songs) are seen as constitutive in knowledge production and life transformation. …”
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ORTAÇAĞDA İLK ÜNİVERSİTELER : STUDIUM GENERALE by Fatih Rukancı, Hakan Anameriç

“…The universities of the middle ages, constituted as a form of conventional society at the beginning, are also elucidated by means of their roles and contributions to exploring new scientific branches. …”
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Le fondement démocratique du droit de décider des Catalans by Mercè Corretja Torrens

“…This new right that has been recognized in some democratic plural states, could also find its anchorage in the Spanish Constitution of 1978. Finally, the prospect of initiating a process of remedial secession according to international law is explored, in case the exercise of the right to decide is blocked.…”
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La grande enfance by Jean-François Dupeyron

“…Thus, this representation provides today a real ‘scholarly rumour’ about the discovery of the childhood during the occidental modernity and constitutes the hard core of a paradigm. The critic of this paradigm comes along with several propositions to take a fresh look at the childish subjectivity, from the phenomenology of the childish life and with the support of Michel Henry’s and Georges Canguilhem’s works. …”
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La stratégie de la « smart city » au Japon : expérimentations nationales et circulations globales by Raphaël Languillon-Aussel, Nicolas Leprêtre, Benoit Granier

“…The “smart” cities constitute a new urban imaginary which has recently been spreading through the world, in particular in East Asia, North America, and Europe. …”
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Adopting 4-H Club Bylaws by Keith G. Diem, Judy Levings, Ben Knowles

“…For the same reason our country needs a constitution! By having fair and written rules, the rights of all members can be protected. …”
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The Recategorization of the Rheme and the Structure of the Oral Paragraph in French and in Finnish by Mari Lehtinen

“…This paper aims, however, at showing that the discourse-structuring role of the utterance-final pitch rises in spontaneous spoken Finnish is in many respects reminiscent of the final pitch rises that constitute an essential component of the French intonation system (Morel & Danon-Boileau, 1998). …”
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Umori preriformistici in un umanista meridionale: Antonio Galateo by Domenico Defilippis

“…Its positions are revealed a great deal next to those of Erasmo da Rotterdam and they anticipate some of the motivations that would have brought to the Lutheran reform, although Galateo never refuses the supremacy and the orthodoxy of Saint Roman Church. Its thought constitutes an unusual testimony of that modern devotio, that would also have received not little succession in the.…”
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3D Fiber-Based Frame Element with Multiaxial Stress Interaction for RC Structures by Alexander Kagermanov, Paola Ceresa

“…The element formulation relies on the classical Timoshenko beam theory combined with sectional fiber discretization and a triaxial constitutive model for reinforced concrete consisting of an orthotropic, smeared crack material model based on the fixed crack assumption. …”
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Le mausolée turriforme d’une villa près de Carcassonne/Carcasso (Aude) by Richard Pellé

“…Owing to its chronology, it constitutes a category of monument with an underground funeral chamber, which seems to be rare in Gaul or in the western part of the Empire and remains exceptional for this important time of the change of era.…”
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Solar GHI Ensemble Prediction Based on a Meteorological Model and Method Kalman Filter by Yuanyuan Liu

“…As the accuracy of the version output related to its specific position is often questionable, group prediction constituting three members is suggested and agreed upon measurement. …”
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Quelle place pour le pluralisme religieux dans le mouvement de protestation algérien de 2019 ? by Zohra Aziadé Zemirli

“…The Algerian popular movement and the project to create a new Constitution could allow the dialogue around religious freedom, the separation between the state and religion, and laicism – the three having an impact on religious minorities in the country – to take place.…”
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Economical aspect of Turkish sports federations before and after gaining autonmy (the case of Voleyball Federation of Turkey) by Bülent Fısekcıoglu, Ezgi Ertuzun

“…In this respect, Football Federation and federations in Europe which have the experience ofautonomy constitute a model and it is observed that they are successful in this point.…”
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La recherche en sciences sociales dans les écoles de paysage en France by Monique Toublanc

“…This approach is claimed by the professionals of landscape and constitutes a hotbed for the development of a new theoretical field for researchers in social sciences and landscape architects. …”
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Étude exploratoire des obstacles à la transition universitaire selon le vécu d’étudiants français et belges by Mikaël De Clercq, Cathy Perret

“…Transition to Higher Education constitutes a challenging adjustment step for students that deserves major investigation. …”
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