The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target by Reem Alharthi, Monica Sueiro-Olivares, Isabelle Storer, Hajer Bin Shuraym, Jennifer Scott, Reem Al-Shidhani, Rachael Fortune-Grant, Elaine Bignell, Lydia Tabernero, Michael Bromley, Can Zhao, Jorge Amich

“…We identified a set of 15 genes that were consistently expressed at higher levels in vivo than in vitro, suggesting that they may be particularly relevant for intrapulmonary growth and thus constitute promising drug targets. Indeed, the role of 5 of the 15 genes has previously been empirically validated, supporting the likelihood that the remaining candidates are relevant. …”
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Blended digital health intervention for adolescents at high risk with digital media use disorders: protocol for a randomised controlled trial within the Res@t-Consortium by Oliver Labrenz, Oliver Labrenz, Lucie Waedel, Lucie Waedel, Michael Kölch, Michael Kölch, Susanne Lezius, Christina Wacker, Antonia Fröhlich, Antonia Fröhlich, Kerstin Paschke, Rainer Thomasius, Olaf Reis, Olaf Reis

“…Secondary outcomes include EEG measurements and changes in standardised psychopathological variables.DiscussionShould the Res@t app prove efficacious when compared to a waitlist control group, it would constitute an evidence-based intervention for the treatment of DMUD in children and adolescents. …”
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A Newborn with Genital Ambiguity, 45,X/46,XY Mosaicism, a Jumping Chromosome Y, and Congenital Adrenal Hyperplasia by Lei Zhang, Linda D. Cooley, Sonal R. Chandratre, Atif Ahmed, Jill D. Jacobson

“…This is the first case of coexisting CAH and 45,X/46,XY mosaicism reported in the English literature and the third case of a constitutional chromosome Y “jumping translocation.” Our report documents the medical and genetic complexity of children such as this one with ambiguous genitalia and discusses the need for a multidisciplinary team approach.…”
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Introducing the Condor Array Telescope. V. Deep Broad- and Narrowband Imaging Observations of the M81 Group by Kenneth M. Lanzetta, Stefan Gromoll, Michael M. Shara, David Valls-Gabaud, Frederick M. Walter, John K. Webb

“…Here we describe the acquisition and processing of these observations, which together constitute unique very deep imaging observations of a large portion of the M81 Group through a complement of broad- and narrowband filters. …”
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Riverine microplastic discharge along the southern Black Sea coast of Türkiye by Yahya Terzi, Rafet Çağrı Öztürk, Ahmet Raif Eryaşar, İlhan Yandi, Ahmet Şahin, Fatih Yılmaz, Kenan Gedik, Sedat Gündoğdu

“…MP sizes ranged predominantly between 200–1000 μ m, and fibers constituted the majority of shapes (64.1%), followed by fragments (28.3%). …”
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B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis by Xin Wei, Weifeng Yao, Huiping Li, Jingjing Qian, Yaosheng Xie, Zhuo Zhang, Hong Lu, Liang Shi, Xiangyang Lin

“…Materials and Methods. 131 acute pancreatitis (AP) patients and 11 chronic pancreatitis (CP) patients constituted the patients’ group; 20 healthy individuals were enrolled as healthy controls (HC). …”
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Child Injury in Israel: Emergency Room Visits to a Children's Medical Center by Michal Hemmo-Lotem, Claudia Jinich-Aronowitz, Liri Endy-Findling, Michal Molcho, Michal Klein, Yehezkel Waisman, Yehuda L. Danon, Joav Merrick

“…Despite this low rate of non-Jewish patients, however, they constituted 20% of later hospitalizations. The main injuries recorded were bruises and wounds from blunt objects, falls, motor vehicle–related accidents, and sport injuries. …”
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A compressive damage model for a rock considering the microcrack mechanical behavior by Cui LIU, Zhong LI, Feiya XU, Mo ZHANG, Xiaowei CAO, Heng LEI

“…This study provides new insight into the establishment of the rock damage constitutive model under compression.…”
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Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

“…Various factors alter the gut microbiota which lead to dysbiosis; in particular, diet and dietary fibers constitute important determinants. Dietary fiber protects against IBD; bacteria ferment these dietary fibers in colon and generate short-chain fatty acids (SCFAs), which mediate the anti-inflammatory actions of dietary fibers. …”
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Primary Fallopian Tube Carcinoma: Results of a Single-Institutional Retrospective Analysis of 17 Patients with Evaluation of Staging and Prognostic Factors by Neserine Tounsi, Hanen Bouazize, Ikram Margheli, Nadia Boujelbene, Hechiche Monia, Maher Slimane, Khaled Rahel

“… OBJECTIVE: Primary carcinoma of the fallopian tubes is one of the less common gynecological cancers. It constitutes (0.14-0.18%) of gynecological malignancies. …”
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Eight-element flexible MIMO antenna based on characteristics mode theory with enhanced channel capacity for sub 6 GHz 5G communications by Deepthi Mariam John, Shweta Vincent, Sameena Pathan, Kunjan D Shinde, B S Supreetha, Tanweer Ali

“…The single-element antenna constitutes a co-planar waveguide (CPW) fed transformed circular monopole antenna designed using the theory of characteristic modes (CMA) to cover the specific band. …”
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Molecular assessment of splicing variants in a cohort of patients with inborn errors of immunity: methodological approach and interpretation remarks by Laura Miguel Berenguel, Carla Gianelli, Carla Gianelli, Carla Gianelli, Elisabet Matas Pérez, Teresa del Rosal, Ana Méndez Echevarría, Ángel Robles Marhuenda, Marta Feito Rodríguez, Maria Teresa Caballero Molina, Maria Teresa Caballero Molina, Lorena Magallares García, Brenda Sánchez Garrido, Samantha Hita Díaz, Luis Allende Martínez, Luis Allende Martínez, Pilar Nozal Aranda, Pilar Nozal Aranda, Pilar Nozal Aranda, Carmen Cámara Hijón, Carmen Cámara Hijón, Carmen Cámara Hijón, Eduardo López Granados, Eduardo López Granados, Eduardo López Granados, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, María Bravo García-Morato, María Bravo García-Morato, María Bravo García-Morato

“…Reverse transcription-polymerase chain reaction (RT-PCR) is the molecular assay employed for pathogenicity validation.ResultsWe detected 23 patients of 20 pedigrees with splicing variants in IEI genes, which constitutes the 12.3% of our cohort. In total, 21 splicing variants were analyzed, 10 of which had previously been reported in the literature and 11 novel ones. …”
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Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances by Merve Kulbay, Nicolas Tuli, Massimo Mazza, Armaan Jaffer, Sarinee Juntipwong, Emily Marcotte, Stuti Misty Tanya, Anne Xuan-Lan Nguyen, Miguel N. Burnier, Hakan Demirci

“…Extraocular extension, recurrence, and metastasis constitute the major challenges of conventional treatments. …”
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Research hotspots and trends in the antioxidant effects of acupuncture: A bibliometric analysis from 2003 to 2024 by Zhilin Huang, Song Li, YiHao Zhou, Anhong Dai, Yi Zhang, Meifang Liu, Mengqi Le, Jing Shi

“…Results: A total of 438 articles have been published in the field, with the number increasing yearly. Chinese scholars constitute a significant force in the domain of research pertaining to this field. …”
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Virtual Joint Field Campaign: a framework of synthetic landscapes to assess multiscale measurement methods of water storage by T. Francke, C. Brogi, A. Duarte Rocha, M. Förster, M. Heistermann, M. Köhli, D. Rasche, M. Reich, P. Schattan, P. Schattan, L. Scheiffele, M. Schrön

“…</p> <p>In this study we suggest a synthetic virtual landscape that allows for an exact definition of all variables of interest and, consequently, constitutes the so-called “virtual truth” free of knowledge gaps. …”
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Appendicular Skeletal Muscle Index Is Positively Related to Mediterranean Diet Adherence in University Students by Paraskevi Detopoulou, Olga Magni, Ioanna Pylarinou, Despoina Levidi, Vassilios Dedes, Milia Tzoutzou, Konstantina Argyri, Evangelia Fappa, Aristea Gioxari, George Panoutsopoulos

“…The appendicular skeletal muscle index (aSMI) represents the skeletal muscle mass “corrected” for height and constitutes a clinically applicable feature of sarcopenia. …”
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Influence of Enhanced Recovery Pathway on Surgical Site Infection after Colonic Surgery by Caroline Gronnier, Fabian Grass, Christiane Petignat, Basile Pache, Dieter Hahnloser, Giorgio Zanetti, Nicolas Demartines, Martin Hübner

“…Colonic surgical patients operated between May 2011 and September 2015 constituted the cohort for this retrospective analysis. …”
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Transforming monosaccharides: Recent advances in rare sugar production and future exploration by Shin-ichi Nakakita, Jun Hirabayashi

“…In this scenario, monosaccharides, which constitute various kinds of glycans in nature, are assumed to have been generated by formose reactions on the prebiotic Earth (chemical evolution era). …”
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Analytical Performances of Human Immunodeficiency Virus Type 1 RNA-Based Amplix® Real-Time PCR Platform for HIV-1 RNA Quantification by Christian Diamant Mossoro-Kpinde, Ralph-Sydney Mboumba Bouassa, Mohammad-Ali Jenabian, Serge Tonen Wolyec, Leman Robin, Mathieu Matta, Jean de Dieu Longo, Gérard Grésenguet, Laurent Andreoletti, Laurent Bélec

“…The HIV-1 RNA-based Amplix real-time PCR platform constitutes sensitive and reliable system for clinical monitoring of HIV-1 RNA load in HIV-1-infected children and adults, particularly adapted to intermediate laboratory facilities in sub-Saharan Africa.…”
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Metagenomic analysis of goat feces from Ogliastra (Sardinia, Italy) by Monica Rosaria Molotzu, Piera Angela Cabras, Lisa Di Marcantonio, Rossano Atzeni, Nicolò Pietro Paolo Macciotta, Antonella Canu

“…With its constitutive and functional characteristics, the intestinal microbiota plays a crucial role in the health condition of the animals. …”
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