Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

“…Conclusion The HSF1‐MYCN axis constitutes a transcription‐dependent regulatory mechanism that may function as both a prognostic indicator and a promising therapeutic target in liver cancer. …”
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Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation by Herbert Izo, Ninsiima, Ejike, Daniel Eze, Kenneth, Ssekatawa, Halima, Nalugo, Caroline, Asekenye, David, Onanyang, Edson Ireeta, Munanura, Moses, Ariong, Kevin, Matama, Gerald, Zirintunda, Ngala Elvis, Mbiydzenyuy, Fred, Ssempijja, Adam Moyosore, Afodun, Ibe Michael, Usman, Oscar Hilary, Asiimwe, Julius, Tibyangye, Keneth Iceland, Kasozi

“…In this study, green tea silver nitrate nanoparticles were characterized and the extract were made up to constitute high (100%), medium (10%), and low (1%) concentrations for administration. …”
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Financial Management Practices and Financial Performance of Micro Finance Institutions. A Case Study of Lyamujungu SACCO Kabale District. by Komuhangi, Jacenta

“…The primary method of data collection was the self-administered questionnaire while correlation constituted data analysis. The findings indicate that internal control systems, cash flow management, and working capital management significantly affect financial performance of microfinance institutions. …”
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Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

“…M. smithii seems to interact with the bacterial ecosystem affecting butyrate, histidine, phenylalanine, and linoleic acid metabolism with a positive impact on cognition, constituting a promising therapeutic target to enhance cognitive performance, especially in subjects with obesity.…”
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CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids by Alexander Hennig, Laura Wolf, Beatrix Jahnke, Heike Polster, Therese Seidlitz, Kristin Werner, Daniela E. Aust, Jochen Hampe, Marius Distler, Jürgen Weitz, Daniel E. Stange, Thilo Welsch

“…Subtyping of human PDACs using CFTR might constitute an alternative to HNF1A and should be further investigated.…”
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Effectiveness of a pharmacist-led tele-psychiatric clinic in managing drug-related problems by Majed Al Shakhori, Savera Arain, Suhaj Abdulsalim, Mohammed Salim Karattuthodi, Marwa Al Dhamen, Shoruq Almutairi, Shabeer Ali Thorakkattil, Dina Alahmdi, Vijayanarayana Kunhikatta, Abdul Sammad AlJishi

“…Noteworthy interventions also encompassed the identification and management of potential or suspected adverse reactions, comprising 12.35% of the interventions, along with interventions addressing concerns regarding potentially ineffective therapy, which constituted 11.59%.Conclusion: The study underscores the critical role of pharmacists in psychiatric care, with high physician acceptance of their interventions. …”
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Thulium laser enucleation of the prostate plus thulium fiber laser therapy for benign prostatic hyperplasia combined with bladder stones by Chen Wang, Yuanwei Li, Yongjun Yang, Junjie Chen, Zhuo Li, Guangqing Song, Jia Chen, Liu Zhe, Yili Teng, Qiang Lu

“…Materials and methods: Thirty-one patients with BPH complicated by BSs who underwent ThuLEP+TFL at our institution between October 2020 and September 2022 were included in the observation group, while 31 patients undergoing TUEP plus bladder lithotomy during the same period constituted the control group. Data collection involved assessing differences in the International Prostate Symptom Score (IPSS), hemoglobin (Hb) levels, maximum urinary flow rate (Qmax), and quality of life (QoL) before and after surgery, along with follow-up results. …”
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Perception of phage therapy and research across selected professional and social groups in Poland by Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki

“…To the best of our knowledge, with 1,098 collected questionnaires, this article constitutes the first large-scale analysis on phage therapy perceptions, interest and knowledge among ordinary people in a country with a long, internationally recognized, tradition of treating patients with phages. …”
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The DnaJ-Hsp70-Hsp90 co-chaperon networks in scallops under toxic Alexandrium dinoflagellates exposure by Moli Li, Jie Cheng, Huizhen Wang, Jiaoxia Shi, Xiaogang Xun, Wei Lu, Xubo Wang, Jingjie Hu, Zhenmin Bao, Xiaoli Hu

“…A large set of co-chaperons comprising J-domain proteins (DnaJs) regulate the ATPase cycle of Hsp70s with Hsp90s, together constituting a dynamic and functionally versatile network for protein folding/unfolding and regulation. …”
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Clinical and Imaging Features of Familial and Sporadic Multiple Sclerosis by Kamal AmirAshjei Asalemi, Alia Saberi, Amirreza Ghayeghran, Sima Fallah Arzpeyma, Sharareh Eskandarieh, Mohammad Ali Sahraian, Hamidreza Hatamian, Kasra Sarlak, Negin Ashoori, Nima Broomand Lomer

“…While most cases are sporadic, familial MS (FMS) constitutes approximately 12.6% of the MS population and is characterized by affected family members. …”
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HDAC10 and its implications in Sézary syndrome pathogenesis by Monika Pieniawska, Karolina Rassek, Bogumiła Skwara, Magdalena Żurawek, Iwona Ziółkowska-Suchanek, Lydia Visser, Monique Lodewijk, Małgorzata Sokołowska-Wojdyło, Małgorzata Sokołowska-Wojdyło, Berenika Olszewska, Roman J. Nowicki, Roman J. Nowicki, Tomasz Stein, Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Marta Szymoniak-Lipska, Natalia Rozwadowska, Katarzyna Iżykowska

“…Two main types of CTCL constitute of Mycosis Fungoides (MF), a more indolent form of the disease, and Sézary syndrome (SS), the aggressive and leukemic variant with blood involvement. …”
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The Role of Extracts of Edible Parts and Production Wastes of Globe Artichoke (<i>Cynara cardunculus</i> L. var. <i>scolymus</i> (L.)) in Counteracting Oxidative Stress by Valentina Laghezza Masci, Irene Mezzani, Enrica Alicandri, William Tomassi, Anna Rita Paolacci, Stefano Covino, Vittorio Vinciguerra, Elisabetta Catalani, Davide Cervia, Mario Ciaffi, Stefania Garzoli, Elisa Ovidi

“…Fiori) generates substantial quantities of by-products, including leaves, stems, and roots, which constitute potential sources of bioactive compounds and prebiotic dietary fiber. …”
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Interpretation of indoor air surveillance for respiratory infections: a prospective longitudinal observational study in a childcare settingResearch in context by Caspar Geenen, Steven Traets, Sarah Gorissen, Michiel Happaerts, Kurt Beuselinck, Lies Laenen, Jens Swinnen, Sien Ombelet, Joren Raymenants, Els Keyaerts, Emmanuel André

“…Summary: Background: Sampling the air in indoor congregate settings, where respiratory pathogens are ubiquitous, may constitute a valuable yet underutilised data source for community-wide surveillance of respiratory infections. …”
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Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in Mozambique: protocol by Alexandra Wharton-Smith, Caterina Guinovart, Pedro Aide, Francisco Saute, Alfredo Mayor, Bryan Greenhouse, Baltazar Candrinho, Joshua L Proctor, Arantxa Roca-Feltrer, Clemente da Silva, Eduard Rovira-Vallbona, Craig Bonnington, Caitlin Bever, Arlindo Chidimatembue, Maria Rodrigues, Neide Canana, Paulo Arnaldo, Simone Boene, Sonia Enosse

“…Introduction Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. …”
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Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research by Totadri Dhimal, MD, Paula Cupertino, PhD, Aqsa Ghaffar, BS, Yue Li, PhD, Xueya Cai, PhD, Cristopher Soto, BS, Megha Ramaswamy, PhD, MPH, Bruce W. Herdman, PhD, Fergal J. Fleming, MD, MPH, Anthony Loria, MD, MSCI

“…The US prison system detains around 2 million individuals, mainly young, indigent males from ethnic and racial minorities. The constitutional right to healthcare does not protect this population from unique health challenges and disparities. …”
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Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Background: Severe endometrial injury constitutes a significant risk to female fertility, often leading to the development of intrauterine adhesions. …”
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Evaluating the efficacy of carbetocin versus oxytocin for preventing intraoperative blood loss, early postpartum hemorrhage, and maintaining a favorable hemodynamic profile in lowe... by Bisma Fayaz, Raja Suhail Shounthoo, Ajaiz Rasool, Saima Wani, Showkat Ahmad Gurcoo

“…Uterine atony, characterized by inadequate uterine muscle tone, constitutes approximately 70% of PPH cases. The initial step in medical management involves the use of uterotonic agents such as oxytocin, ergot alkaloids, and prostaglandins. …”
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Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA) by Marek Milewski, Aneta Desperak, Maciej Koźlik, Marta Bujak, Marek Gierlotka, Krzysztof Milewski, Krystian Wita, Zbigniew Kalarus, Joanna Fluder-Włodarczyk, Pawel E. Buszman, Jacek Piegza, Mamas A. Mamas, Wojciech Wojakowski, Pawel Gasior

“…Abstract Myocardial infarction with nonobstructive coronary arteries (MINOCA) constitutes 3–15% of all acute myocardial infarctions. …”
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Reduced Expression of Antimicrobial Protein Secretory Leukoprotease Inhibitor and Clusterin in Chronic Rhinosinusitis with Nasal Polyps by Yanran Huang, Ming Wang, Yu Hong, Xiangting Bu, Ge Luan, Yang Wang, Ying Li, Hongfei Lou, Chengshuo Wang, Luo Zhang

“…Antimicrobial peptides and proteins (AMPs) constitute the first line of defense against pathogenic microorganisms in the airway. …”
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miRNAs and Hematological Markers in Non-Alcoholic Fatty Liver Disease—A New Diagnostic Path? by Agata Michalak, Małgorzata Guz, Joanna Kozicka, Marek Cybulski, Witold Jeleniewicz, Ilona Telejko, Karolina Szczygieł, Ewa Tywanek, Halina Cichoż-Lach

“…<b>Background:</b> Asymptomatic liver steatosis constitutes an emerging issue worldwide. Therefore, we decided to explore relationships between selected types of microRNAs (miRNAs), serological markers of liver fibrosis and hematological parameters in the course of non-alcoholic fatty liver disease (NAFLD). …”
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