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3981
Analysis of thyroid function and structure and serum metabolomics in pregnant rats exposed to airborne contaminants: Combined perchlorate, thiocyanate, and nitrate exposure
Published 2025-01-01“…Objectives: Perchlorates, nitrates, and thiocyanates constitute environmental endocrine disruptors; however, health damage caused by absorption through the respiratory tract remains poorly studied. …”
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3982
Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients
Published 2024-01-01“…Background/Aim: Hypertension is a consequence of a neuromodulatory imbalance and is directly associated with cardiovascular diseases. Oxidative stress constitutes an intermediate pathophysiological mechanism for hypertension and cardiovascular disease. …”
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3983
Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker
Published 2025-01-01“…The new OXA variant identified, OXA-1238, could constitute a useful molecular marker for species identification.…”
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3984
Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells
Published 2019-01-01“…Cloning by limiting dilution from a hOE heterogeneous primary culture was performed to obtain a culture predominantly constituted by hONPC. Effectiveness of cloning to isolate MpSC-like precursors was corroborated through immunodetection of specific protein markers and by functional criteria such as self-renewal, proliferation capability, and excitability of differentiated progeny. …”
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3985
The prognostic significance of tertiary lymphoid structures in oral squamous cell carcinomas: a systematic review
Published 2025-01-01“…Among these, oral squamous cell carcinomas (OSCC) constitute the majority. OSCC has a low 5-year survival rate due to late-stage diagnosis. …”
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3986
Domestication of different varieties in the cheese-making fungus Geotrichum candidum
Published 2023-05-01“…Commercial starter strains were scattered across the cheese clade, thus not constituting a single clonal lineage. The cheese populations were phenotypically differentiated from other populations, with a slower growth on all media, even cheese, a prominent production of typical cheese volatiles and a lower proteolytic activity. …”
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3987
Split-Cre-mediated GFP expression as a permanent marker for flagellar fusion of Trypanosoma brucei in its tsetse fly host
Published 2025-02-01“…We showed that cells that acquired the second half Cre through flagellar fusion were permanently modified and that the cells and their progeny constitutively expressed GFP. When tsetse flies were co-infected with N-Cre and C-Cre cells, GFP-positive trypanosomes were observed in the midgut and proventriculus 28–34 days post-infection. …”
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3988
Molecular Detection of Antibiotic-Resistant Genes in Pseudomonas aeruginosa from Nonclinical Environment: Public Health Implications in Mthatha, Eastern Cape Province, South Africa
Published 2021-01-01“…This is concerning as it poses a risk to the environment and constitutes a public health threat. Given the public health relevance, the paper recommends monitoring of multidrug-resistant pathogens in effluent environments.…”
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3989
Bioactive Sesquiterpenoids from <i>Santolina chamaecyparissus</i> L. Flowers: Chemical Profiling and Antifungal Activity Against <i>Neocosmospora</i> Species
Published 2025-01-01“…Among sesquiterpenoids, which constituted the major fraction (50.4%), compounds featuring cedrane skeleton (8-cedren-13-ol), aromadendrene skeleton (such as (−)-spathulenol, ledol, alloaromadendrene oxide, epiglobulol, and alloaromadendrene), hydroazulene skeleton (ledene oxide, isoledene, and 1,2,3,3a,8,8a-hexahydro-2,2,8-trimethyl-,(3a<i>α</i>,8<i>β</i>,8a<i>α</i>)-5,6-azulenedimethanol), or copaane skeleton (<i>cis</i>-α-copaene-8-ol) were predominant. …”
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3990
Qualitative evaluation of the implementation and national roll-out of the NHS App in England
Published 2025-01-01“…NHS staff viewed the app as constituting core NHS infrastructure in the long term which made it appealing, even though initially there was less recognition of its immediate value. …”
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3991
A supervised model to identify wolf behavior from tri-axial acceleration
Published 2025-01-01“…Classification performance was consistently poorer for rare behaviors, which constituted less than 1.1% of the training dataset. …”
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3992
Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells
Published 2024-12-01“…Abstract Double negative T (DNT) cells are a unique subset of CD3 + TCRαβ + T lymphocytes that lack CD4, CD8, or NK1.1 expression and constitute 3–5% of the total T cell population in C57BL/6 mice. …”
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3993
Molecular Alterations of KIT Oncogene in Gliomas
Published 2007-01-01“…KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. Currently, KIT constitutes an attractive therapeutic target. In the present study we assessed the frequency of KIT overexpression in gliomas and investigated the genetic mechanisms underlying KIT overexpression. …”
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3994
Manière de dire et manière d’exercer la parenté en Kabylie. Pour une approche renouvelée du croisement genre et fait matrimonial
Published 2023-12-01“…This contribution aims to provide a critical examination of the notion of marriage in terms of exchange and the sharing of rights over women.The exercise involves highlighting the limitations of a theory that considers women to only appear in the matrimonial market as objects or symbols whose meaning is constituted outside of them (according to P. Bourdieu) or as the ultimate gift, among those that can be obtained through reciprocal gifts (according to C. …”
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3995
Secondary hyperoxaluria: Cause and consequence of chronic kidney disease
Published 2025-01-01“…Different immunomodulatory drugs, microbiome modifiers and SGLT2 inhibitors could constitute new therapeutic targets. Currently, specific treatments for secondary hyperoxaluria are lacking, making early diagnosis and preventive measures against kidney failure the main therapeutic strategies. …”
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3996
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)
Published 2025-01-01“…Developmentally regulated transcription factors hold promise in the quest because these transcriptional regulators constitute the gene regulatory networks driving cell fate determination. …”
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3997
Multi-scale channel attention U-Net: a novel framework for automated gallbladder segmentation in medical imaging
Published 2025-01-01“…The images and ground truth constitute a dataset, which was proportionally divided into a training set (54%), a validation set (6%), and a test set (40%). …”
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3998
Desregulación emocional en población con TDAH; una aproximación teórica/Emotional dysregulation in the population with ADHD. A Theoretical Approach
Published 2019-06-01“…English Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, whose nuclear symptoms constitute inattention, hyperactivity and impulsivity, the latter may be verbal, motor and cognitive, but also emotional, expressed by emotional dysregulation, which affects a person’s ability to emotionally self-regulate and inhibit emotions. …”
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3999
A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes
Published 2019-06-01“…The formal taxonomic changes are limited in part because of the ad hoc nature of taxon and specimen selection, based purely on the availability of data. The phylogeny constitutes a framework for enabling future taxonomically targeted studies using deliberate specimen selection. …”
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4000
Modelling Hysteresis in Shape Memory Alloys Using LSTM Recurrent Neural Network
Published 2024-01-01“…The complex behavior of shape memory alloys (SMAs), characterized by hysteresis and nonlinear dynamics, results in complex constitutive equations. To circumvent the complexity of solving these equations, a black box neural network (NN) has been employed in this research to model a rotary actuator actuated by an SMA wire. …”
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