The Effect of Volitional Preemptive Abdominal Contraction on Biomechanical Measures During A Front Versus Back Loaded Barbell Squat by Joseph B. McCormick, Alexander S. Drusch, Darragh J. Lynch, Gesine H. Seeber, Katherine F. Wilford, Troy L. Hooper, Brad S. Allen, Dennis G. O’Connell, Maria J. Mena-Iturriaga, Kinyata J. Cooper, Phillip S. Sizer

“…Subjects completed informed consent, demographic/medical history questionnaires and an instructional video. …”
Get full text

Suboptimal Blood Pressure Control, Associated Factors, and Choice of Antihypertensive Drugs among Type 2 Diabetic Patients at KCMC, Tanzania by Gabriel W. Mbwete, Kajiru G. Kilonzo, Elichilia R. Shao, Nyasatu G. Chamba

“…Data were collected using structured questionnaires, and written informed consent was obtained. Suboptimal BP was defined as BP levels≥140/90 mmHg according to the American Diabetes Association guideline published in 2018. …”
Get full text

Serum cardiac and inflammatory biomarker levels following chemotherapy among female patients with breast cancer attending at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiop... by Muluabay Getie, Biset Asrade Mekonnen, Daniel Seifu, Yonas Mulugeta, Solomon Tebeje, Chernet Tafere, Asmare Amuamuta

“…After obtaining informed consent, 40 paired samples (40 samples before chemotherapy and 40 matched samples after three cycles of chemotherapy) were collected between May 2018 and March 2019. …”
Get full text

Knowledge, attitudes and practices of healthcare professionals in the management of patients with hypertension and concurrent bronchial asthma: a cross-sectional study in the Yello... by Yang Yang, Wenwen Xu, Fei Yu, Xiaohong Yan, Xingbin Ma, Jinxiang Gao

“…The reporting of this study followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist.Setting From 30 March to 15 April 2024 at 66 various level hospitals and community health service centres.Participants Physicians and nurses specialising in clinical internal medicine, each with over 2 years of practice and who provided informed consent.Primary and secondary outcome measures The demographic characteristics of the healthcare professionals and their KAP towards the Management of Patients with Hypertension and Concurrent Bronchial Asthma were collected using a self-administered questionnaire. …”
Get full text

Predictors of non-response to successive waves of surveys in the Japan Environment and Children’s Study during the 3-year postpartum period: a longitudinal cohort study by Mika Kigawa, Akiko Tsuchida, Tomomi Tanaka, Kei Hamazaki, Yuichi Adachi, Hidekuni Inadera, Kenta Matsumura, Haruka Kasamatsu

“…The self-administered questionnaires that we used in this study were then distributed by mail every 6 months until the children were 3 years old, for a total of six times.Participants Of 103 060 mothers who consented to participate in the JECS during pregnancy, 88 489 mothers were included in the study after excluding those with multiple births, miscarriages or stillbirths and those who withdrew from the study within 3 years after providing informed consent.Primary and secondary outcome measures Data were collected at the baseline survey on participants’ socioeconomic status, medical history, health status, health-related behaviours and their children’s health conditions and living situations. …”
Get full text

Effect of folic acid supplementation on diminished ovarian reserve: study protocol of a single-centre, open-label, randomised, placebo-controlled clinical trial by Yan Wang, Ling Zheng, Kaijun Liao, Dongli Lu, Jiaxin Wu, Binjin Wu, Zhaochun Wu, Zhenghua Jiang

“…The primary outcome is antral follicle count, and the secondary outcomes are ovarian reserve markers, ovarian low-dose stimulation responses and safety.Ethics and dissemination This study was approved by the Ethics Review Committee of Nanping First Hospital Affiliated to Fujian Medical University on 10 February 2021 (approval number: NPSY202002042). Written informed consent was obtained from all participants prior to randomisation, following a detailed description of the purpose of the study. …”
Get full text

Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples by Esther A. Shiraho, Agola L. Eric, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Robert M. Mugambi, Jackson M. Mwandi, Gerald M. Mkoji

“…Ascaris adult and ova were obtained from naturally infected school children, whose parents/guardians gave consent for their participation in the study. Genomic DNA was extracted using alkaline lysis method and amplified by LAMP at 63°C for 45 minutes. …”
Get full text

Effectiveness of a personal health coaching intervention (diabetescoach) in patients with type 2 diabetes: protocol for an open-label, pragmatic randomised controlled trial by Oliver Faude, Fiona Streckmann, Lukas Zahner, Markus Gerber, Vivien Hohberg, Jan-Niklas Kreppke, Jan Kohl, Eleonora Seelig, Daniel König

“…All participants will be required to provide written informed consent. The results will be published in international peer-reviewed journals.Trial registration number ISRCTN79457541.…”
Get full text

Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country by Ana E. Farfán-García, Chengxian Zhang, Aamer Imdad, Monica Y. Arias-Guerrero, Nayibe T. Sánchez-Alvarez, Rikhil Shah, Junaid Iqbal, Maria E. Tamborski, Oscar G. Gómez-Duarte

“…Ninety children less than 5 years of age were recruited after a written informed consent was obtained from parents or guardians. Forty-five subjects served as cases with ADD and 45 as controls. …”
Get full text

Behavioural patterns of university students during the COVID-19 pandemic: A cross-sectional study of the effects of active transportation, uninterrupted sitting time, and screen us... by Nicolas Jacquemond, Andrés Ladino, Guillaume Chevance, Brice Lefèvre, Gonzalo Marchant

“…Participants (N=2873) completed the International Physical Activity Questionnaire (IPAQ) in an average time of around 15 minutes, after providing digital informed consent. Multiple regression models assessed how time duration of active transportation, uninterrupted sitting time, and screen time studying increased or reduced confinement effects on physical activity and sitting time. …”
Get full text

Prehospital triage of patients with acute cardiac complaints: study protocol of HART-c, a multicentre prospective study by Jan Bosch, Charles JHJ Kirchhof, Mark J Boogers, Enrico de Koning, Tom E Biersteker, Saskia Beeres, Barbra E Backus, Reza Alizadeh Dehnavi, Helen AM Silvius, Martin Schalij

“…Patients are asked for consent for contacting their GPs. The main results of this trial will be disseminated in one paper.Discussion The HART-c study evaluates the efficacy and feasibility of a prehospital triage method that combines prehospital patient assessment and direct consultation of a cardiologist who has access to live-monitored data, hospital data and real-time hospital admission capacity. …”
Get full text

Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial by Nour Elkhair Ali, Lamis AbdelGadir Kaddam, Suad Yousif Alkarib, Babikir Gabir Kaballo, Sami Ahmed Khalid, Abdalazim Higawee, Alaa AbdElhabib, Alaa AlaaAldeen, Aled O. Phillips, Amal Mahmoud Saeed

“…All recruited patients met the inclusion criteria and signed informed consent prior to enrolment. The patients received 30 g/day of GA for 12 weeks. …”
Get full text

Identification of Maltase Glucoamylase as a Biomarker of Acute Kidney Injury in Patients with Cirrhosis by Linda Awdishu, Shirley Tsunoda, Michelle Pearlman, Chanthel Kokoy-Mondragon, Majid Ghassemian, Robert K. Naviaux, Heather M. Patton, Ravindra L. Mehta, Bhavya Vijay, Satish P. RamachandraRao

“…Urine samples were collected at the time of consent. Urine exosome protein content was analyzed, and proteomic data were validated by immunoblotting. …”
Get full text

Prediction of postoperative myocardial injury in patients undergoing laparoscopic pheochromocytoma/paraganglioma resection: protocol for an ambispective cohort study by Yuguang Huang, Yuelun Zhang, Ling Lan, Yi Zhang, Ye Ma, Le Shen, Yifei Zhao, Yaohan Li

“…For external validation, we will use an independent prospective cohort (validation cohort) of patients from 1 March 2023 to 31 May 2025.Ethics and dissemination The study protocol has been approved by the Research Ethics Committee of PUMCH (IRB-K2893). Written informed consent will be obtained from all participants in the prospective cohort before enrolment in the study. …”
Get full text

Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients... by Ken Sugimoto, Tomohiro Katsuya, Kei Kamide, Tomomi Fujisawa, Izumi Shimaoka, Mitsuru Ohishi, Ryuichi Morishita, Toshio Ogihara, Hiromi Rakugi

“…All subjects who gave informed consent for genetic research were divided into two groups: the subjects treated with azelnidipine or temocapril, for 52 weeks. …”
Get full text

Body composition, mitochondrial oxygen metabolism and metabolome of patients with obesity before and after bariatric surgery (COMMITMENT): protocol for a monocentric prospective co... by Sina M Coldewey, Charles Neu, Philipp Baumbach, Utz Settmacher, Kornel Skitek, Hermann Kissler, Ricardo Esper Treml

“…Outcomes will be assessed using paired t-tests, Wilcoxon signed-rank tests and regression analyses.Ethics and dissemination The study was approved by the Ethics Committee of Friedrich Schiller University Jena (2018-1192-BO). Written informed consent will be obtained from all patients prior to enrolment in the study. …”
Get full text

A descriptive analysis of a medical humanitarian aid initiative for quality perinatal management in war-torn Ukraine by Iryna Mogilevkina, Dmytro Dobryanskyy, Rhona MacDonald, Diane Watson, David Southall

“…Methods Data from 28,808 births were collected in specially developed database which contained information on maternal characteristics, course of pregnancy and childbirth, maternal and neonatal outcomes and donated drugs and equipment used. After informed consent, mothers (n = 13735) who agreed to use in labour fetal self-monitoring in addition to standard intrapartum fetal health surveillance, monitored and recorded fetal heart rate changes on a “contraction-by-contraction” basis into a special form. …”
Get full text

Diagnostic performance of the DISQVER metagenomic sequencing tool for the identification of pathogens in febrile neutropenic patients: the ADNEMIA trial by Geneviève Héry-Arnaud, Christophe Burucoa, Marie Kempf, David Boutoille, Yohann Foucher, Philippe Lanotte, Maxime Pichon, Stéphane Corvec, Cécile Le Brun, Helene Pailhories

“…All participants will provide informed consent before participation. The trial has been registered on ClinicalTrials.gov (identifier NCT06075888). …”
Get full text

Effect Of Exercise Therapy on Lipid Profile and Oxidative Stress Indicators in Patients with Type 2 Diabetes by Madeeha Jadoon, Shazia Zeb, Sajid Razaq, Munazza Khan, Muhammad Shoaib, Sara Mariyum

“…Criteria for patient selection were a T2DM duration of at least one year and patients aged between 28-45 years with or without consent to enrol for the study. Information was gained through questionnaires, satisfaction surveys, physical assessments, and biochemical assays. …”
Get full text

Changes in soft and hard tissue of central incisor before and after distal migration of the maxillary dentition in adult patients with different periodontal phenotypes by CHEN Rui, HAN Shuang, AN Qi

“…Methods The study was approved by the hospital ethics committee, and the patients signed the informed consent form. Fifty-two adult patients in the orthodontic department of Hefei Stomatological Hospital were selected and divided into thick gingival and thin gingival groups, with 26 cases in each group. …”
Get full text