Effectiveness of using Glutamyl-cysteinyl-glycine disodium immunomodulator in patients with destructive multidrug-resistant tuberculosis of lungs by A. S. Shalmin, E. N. Raznatovskaya

“…On the basis of standard chemotherapy course main treatment effectiveness parameters have been estimated of 30 patients who were treated with implementation of GCGD on the basis of standard chemotherapy course and 30 patients who were treated with standard chemotherapy course alone. Conclusion. Complex treatment of patients with destructive MDR with implementation of GCGD immunomodulator on the basis of standard chemotherapy course for immunity state correction allows to increase effectiveness of treatment by 33,3%.…”
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MICRORHEOLOGY OF ERYTHROCYTES IN ARTERIAL HYPERTENSION AND DYSLIPIDEMIA WITH A COMPLEX HYPOLIPIDEMIC TREATMENT by I. N. Medvedev

“…Prescription of non-drug management and simvastatin to the studied patients does normalize their cytoarchitectonics and spontaneous erythrocyte aggregation in 6 weeks of treatment, having retained the results for at least the following 98 weeks of treatment.Conclusion. Complex application of non-medication treatment and simvastatin does normalize erythrocyte microrheologic properties for 6 weeks in hypertension patients with dyslipidemia.…”
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Clinical and functional manifestations of hypervolemia in patients with arterial hypertension by O. B. Poselyugina, S. A. Nilova, V. S. Volkov, Al Galban Hakhed

“…Indirect markers of hypervolemia in AH patients included higher salt intake, low effectiveness of standard antihypertensive therapy (AHT), disturbed circadian BP rhythm with inadequate nighttime BP reduction, and EchoCG signs of left ventricular volume overload. Conclusion. Complex examination of AH patients helps to identify individuals with clinical and functional manifestations of hypervolemia.…”
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PECULIARITIES OF ENDOMETRIAL STATE OF THE PATIENTS WITH ABNORMAL UTERINE BLEEDING by V. N. Gulieva, A. Kh. Bishtavi, A. Yu. Kostin, A. E. Ivanov, A. G. Solopova, Yu. Yu. Tabakman

“…Results. the structure of pathological changes of endometrium in case of AUB was identified. Conclusion. complex endometrial hyperplasia and atypical endometrial hyperplasia occur without any regularity on the background of various changes of E reflecting the state of both hypo- and hyper-estrogenia.…”
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IMAGING ALGORITHMS FOR OCCLUSIVE CAROTID DISEASE IN TREATMENT STRATEGY by M. V. Vishnyakova

“…For diagnosis of neurologic complication first line examination was MRI, than for further assessment – CTA and CTP.Conclusion. Complex imaging algorithm for occlusive carotid disease assessment, defining of postoperative vascular status and possible neurologic complications provide necessary information for management strategy examination.…”
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Associations between lipids and lung cancer subtypes by Jiayu Wen, Jian-Qing He

“…It was discovered that PC (16:1_20:4) and PC (18:0_20:4) might raise the risk for LUAD. Conclusion Complex lipid metabolic pathways, especially involving PC, are present in NSCLC, and distinct lipid isomers may influence various molecular subtypes in different ways.…”
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The Process of Inefficient Self‐Management in Patients With Myocardial Infarction in Prehospital: A Grounded Theory by Farzaneh Maghaminejad, Shokoh Varaei, Nahid Dehghan‐Nayeri

“…The three major categories of “fighting between awareness and preference,” “taking problematic arbitrary measures,” and “consulting lay people” emerged from the participants' experiences, along with the theme of “inefficient self‐management.” Conclusion Complex situation, unfamiliarity with MI and its management makes MI management very difficult for patients and family members. …”
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Workplace programme of cardiovascular prevention: clinical effectiveness by A. M. Kalinina, A. V. Kontsevaya, S. V. Belonosova, R. A. Eganyan, Yu. M. Pozdnyakov, N. V. Kiseleva

“…Preventive intervention resulted in a significant reduction in systolic BP (SBP) — by 9 mm Hg, in diastolic BP (DBP) — by 9,7 mm Hg, in TC — by 0,7 mmol/l, and also in SCORE-calculated CVD risk — from 3,8 % to 3,0 %. Conclusion. Complex CVD prevention at wp was associated with substantial beneficial effects within first 12 months.…”
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Sustained-release calcium antagonist in patients over 60 years with isolated and systolo-diastolic arterial hypertension by V. E. Oleynikov, V. A. Budanova, E. E. Grishaeva, E. I. Yastrebova, S. S. Fadeeva, L. I. Gusakovskaya

“…Nifedipine SR therapy was associated with substantial BP reduction and improved circadian BP profile in all participants; reduced myocardial hypertrophy in elderly people; normalisation of left ventricular (LV) diastolic function and decreased number of patients with MAU in both groups, especially among those with ISAH.Conclusion. Complex assessment of nifedipine SR clinical effectiveness in ISAH and SDAH patients aged over 60 years demonstrated multiple effects on AH-related parameters and improved circulatory functioning in elderly patients. …”
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War liver injuries by Stanković Nebojša

“…Mortality rates due to the liver injury of the grade III, IV and V were 16.6%, 70.0% and 83.3%, respectively. Conclusion. Complex liver injuries caused very high mortality rate and the management of the injured was delicate under war circumstances (if the injured reached the hospital alive). …”
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Case Report: Complex Regional Pain Syndrome Involving the Head and Face After Severe Malignant Otitis Media and Mastoiditis by Hunter Collins

“…Eleven months after initial symptom onset, she reported significant symptomatic improvement with markedly decreased disability and return to her premorbid quality of life. Conclusion Complex regional pain syndrome is difficult to recognize, there are no diagnostic tests, there is no definitive cure and management is symptomatic. …”
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Non-infectious chronic blepharitis pharmacotherapy by S. N. Sakhnov, S. V. Yanchenko, A. S. Rudashova, A. V. Malyshev

“…It included the following significant changes: reducing the level of subjective discomfort; decreasing of sins of eyelid inflammation; increasing of meibomian gland function; improvement of tear film and ocular surface tissues.Conclusion: Complex treatment, including eyelid hygiene (using Blepharoshampoo, Blepharolotion or Blepharosalfetka, Blepharogel-1), antiinflammatory therapy and artificial tears, allows achieving significant reduction of subjective symptoms and both functional and objective signs of the disease in non-infectious chronic blepharitis patients.…”
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ATRIAL FIBRILLATION ONSET RISK IN PATIENTS WITH METABOLIC SYNDROME: PROSPECTIVE STUDY by A. I. Olesin, V. A. Litvinenko, A. V. Al-Barbari, I. V. Konstantinova, Z. Yu. Smolin, O. N. Prosyanikova

“…Short-term risk (during 1-2 years after the first year postobservational) of AF development in MS can be evaluated only in dynamics: while lowering of AFRI by 20% and more every 3-4 months of observation leads to development of AF during 1-2 years in MS, and in AFRI less than 3 Units with further decline of this parameter by 90% and more during 1-3 months — during 6 months after investigation.Conclusion. Complex investigation of MS patients, that includes assesssment of LAP, Pd, AFRI, improves the evaluation of longand short-term risks of AF development.…”
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Clinical Approach Strategy in Managing Complex Biliary Cases: Lesson Learnt from a Tertiary Referral Private Hospital by Cosmas Rinaldi Adithya Lesmana, Maria Satya Paramitha, Yulia Estu Pratiwi, Laurentius Adrianto Lesmana

“…Around 4.9% of the subjects underwent EUS-guided biliary drainage procedure. Conclusion: Complex biliary cases require a good clinical approach algorithm to decide which procedure comes first based on comprehensive evaluation consists of patient’s factor, expertise, cost, and the risk of complications.   …”
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The connection of polymorphism and diurnal changes of the biological clock gene expression with the risk of progression of primary open-angle glaucoma by A. S. Vlasova, S. A. Petrov, T. N. Malishevskaya, D. G. Gubin, S. N. Kolomeychuk

“…The clock rs1801260 and MTNR1B rs10830963 gene polymorphism was found to be related to disturbances in melatonin production and sleep phase. Conclusion. Complex manifestations of circadian desynchronization accompanying the progressive course of glaucoma are the late phase of rhythms and a decrease in sleep duration, body temperature, salivary melatonin and IOP, internal desynchronization between IOP and body temperature, IOP and sleep, evening dyslipidemia. …”
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On the Issue of Optimizing Surgical Tactics and Blood-Saving Techniques in Case of Placenta Ingrowth Into the Uterine Scar by Z. D. Karimov, B. S. Abdikulov

“…In 8 cases, there was a combination of placenta increta into the uterine scar region of different depths, and in 2 (3.7%) cases, a combined deeply invasive lesion of the posterior wall of the lower segment and the body of the uterus.CONCLUSION Complex compression hemostasis according to R.G. …”
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Cloacal Exstrophy Associated with a Hindgut Duplication Anomaly: A Case Report of Challenges in Hindgut Preservation by Suliaman Alaqeel, Jamila Almaary, Fatmah Alrabodh, Fayez AlModhen

“…This was successfully managed by creating a single-lumen end stoma, preserving the entire length of the hindguts with a wider caliber. In conclusion, complex cases of CE are uncommon, and unexpected operative findings should always be anticipated. …”
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Novel compound heterozygous mutations in LMAN2L cause early childhood refractory epilepsy by Teng Wang, Yan Gao, Yuhan Yan, Ping Yin, Lili Tong, Meng Dong

“…Both cases showed severe postnatal psychomotor developmental lag and developed seizures at 2 months of age, which manifested themselves in a variety of ways and were not relieved by the administration of multiple antiepileptic drugs. Conclusion Complex heterozygous mutations at the newly identified locus of LMAN2L cause refractory epilepsy, with epileptic symptoms beginning at 2 months of age and manifesting as multiple seizure types and developmental delays. …”
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The early and late results of distal pacreatic resection by V. І. Pylypchuk

“…Good late results were obtained in 7 (77.7%) patients after DR for CHP and in 2 (50.0%) – for tumors, satisfactory results – in 2 (22.3%) and in 1 (25.0%) patients, accordingly, and poor result - in 1 (25.0%) after pancreatic DR, performed for malignant tumor. Conclusion. Complex diagnosis of the distal pancreatic segment diseases with obligatory application of computed tomography gives possibility to establish strict indications for operation and to select a mostly adequate method of surgical intervention individually. …”
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Correlation of Complex Impacted Mandibular Teeth with Pericoronitis and Effect of Minimally Invasive Tooth Extraction on Patients’ Long-term Outcome of Masticatory Ability by Tinghong Nie, Bojie Chang, Lili Tian, Shansong Cao, Junjie Wang, Haitao Qi, Lirong Gao

“…Finally, the mastication ability was higher in OG at 7 days postoperatively, but there was no difference between groups at 6 months postoperatively (P>0.05). Conclusion. Complex mandibular impacted teeth can easily induce pericoronitis, so clinicians should pay attention to the influencing factors of pericoronitis. …”
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