Prevalence and Determinants of Home Delivery among Women with Easy Access to Health Facilities in Sub-Saharan African Countries: A Multi-level Mixed Effect Analysis by Berhan Tekeba, Alebachew Ferede Zegeye, Deresse Abebe Gebrehana, Tadesse Tarik Tamir

“…The adjusted odds ratio at the 95% confidence interval (Cl) was computed to assess the strength and significance of the association between explanatory and outcome variables. …”
Get full text

Indirect contacts between Danish pig farms – what are the frequencies and risk-reducing measures, and how can they be used in simulation models? by Mette Fertner, Beate Conrady, Anne Sax Røgind, Elisabeth Okholm Nielsen, Anette Boklund

“…Conclusion Since the inclusion of indirect contacts in disease spread models relies on valid data, the present study provided valuable data regarding the frequencies and biosecurity measures of indirect contacts between Danish pig herds, which may be useful in the parametrization of computational epidemiological models.…”
Get full text

A basis water quality monitoring plan for rehabilitation and protection by M. Enriquez, R. Tanhueco

“…E. coli was also detected in water samples collected in all sampling stations. The computed water quality index of 39.02 described water as poor, always impaired, and threatened by the surrounding environment.  …”
Get full text

Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank by Anthony Kityo, Byeonggeun Choi, Jung-Eun Lee, Chulho Kim, Sang-Ah Lee

“…A UPF metabolomic signature was computed as a weighted sum of UPF-related metabolites, using elastic net coefficients as weights. …”
Get full text

Pharmacognostic analysis and antimalarial evaluation of quercetin in Ilex umbellulata bark using HPTLC, in vitro screening, molecular docking, and network pharmacology by James H. Zothantluanga, Dipak Chetia, Yasangam Umbon, T. C. Lalhriatpuii, Dhritiman Roy, Nidahun Lamare, Salem Lalvenhimi

“…In this study, we aim to develop the missing pharmacognostic parameters with modern analytical techniques and carry out multi-step computational studies to study the antimalarial potential of I. umbellulata. …”
Get full text

Thermal properties and non-bonded interactions in human PMP2 variants: A molecular dynamics study by Prabin Aryal, Jhulan Powrel

“…Many studies on this disease have been conducted, including clinical as well as computational, but no effective medical cure has yet been found. …”
Get full text

A density functional theory investigation of the substituent effect on acyclovir and guanine derivatives for applications on energetic materials by Luciana Amorim da Silva, Gabriel Monteiro-de-Castro, Erick Braga Ferrão Galante, Itamar Borges Jr, Aline Cardoso Anastácio

“…Several molecular properties were computed, including the chemical reactivity, the heat of formation and the detonation velocities and pressures using semiempirical equations. …”
Get full text

Advances in the pilot point inverse method: Où En Sommes-Nous maintenant? by White, Jeremy, Lavenue, Marsh

“…., 2000], but with a particular focus on the incredible adoption and advancement of de Marsily’s PPM and related inverse techniques over the last twenty years in the field of predictive groundwater modeling.Much has been written about the vast array of inverse techniques developed by researchers and practitioners since the 1960s. de Marsily’s PPM, like many methods developed in the late 70s and early 80s, structured its approach to parameterization to overcome many of the challenges of applying inverse methods to real world problems, namely, limited head and transmissivity data relative to the number of unknowns to be estimated, measurement errors, inferred covariance structures of the state variables, and limited computational resources. While inversion research continues, only de Marsily’s PPM has achieved wide-spread adoption within the groundwater modeling community.The reasons for the popularity of the PPM are many but none more important than its adoption by John Doherty’s PEST inversion software in the early 2000s [Doherty, 2003]. …”
Get full text

Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study by Min Liu, Na Yin, Yuhang Zhu, Aili Du, Chunyuan Cai, Pengyuan Leng

“…Causal effects were estimated using the inverse variance weighting (IVW) method, while the Summary Data-based Mendelian Randomization (SMR) method, leveraging pooled data, was applied to compute effect estimates. These estimates were further refined through various approaches including MR-Egger, the weighted median method, simple and weighted models, and leave-one-out analyses to conduct sensitivity analyses.ResultThe analytical outcomes utilizing the IVW method indicated that inhibitors of HMGCR were correlated with an elevated risk of developing gout (IVW: OR [95%CI] = 1.25 [1.03, 1.46], p=0.0436), while PCSK9 inhibitors were linked to heightened levels of urate (IVW: OR [95%CI] = 1.06 [1.01,1.10], p=0.0167). …”
Get full text

SARS-CoV2 pneumonia patients admitted to the ICU: Analysis according to clinical and biological parameters and the extent of lung parenchymal lesions on chest CT scan, a monocentri... by Abed Al Hadi Krisht, Kévin Grapin, Romain Chauvot de Beauchene, Benjamin Bonnet, Lucie Cassagnes, Bertrand Evrard, Mireille Adda, Bertrand Souweine, Claire Dupuis

“…<h4>Objective</h4>The objectives of this study were to measure the prognostic value of the extent of lung parenchymal lesions on computed tomography (CT) and of several coagulation and inflammatory biomarkers, and to explore the characteristics of the patients depending on the extent of lung parenchymal lesions.…”
Get full text

AICpred: Machine Learning-Based Prediction of Potential Anti-Inflammatory Compounds Targeting TLR4-MyD88 Binding Mechanism by Lucindah N. Fry-Nartey, Cyril Akafia, Ursula S. Nkonu, Spencer B. Baiden, Ignatus Nunana Dorvi, Kwasi Agyenkwa-Mawuli, Odame Agyapong, Claude Fiifi Hayford, Michael D. Wilson, Whelton A. Miller, Samuel K. Kwofie

“…Additionally, compounds known to inhibit TLR4, including TAK-242 (Resatorvid) and benzisothiazole derivative (M62812), were predicted as bioactive agents within the applicability domain with probabilities above 0.80. Computationally inferred compounds using AICpred can be explored as potential starting skeletons for therapeutic agents against hyperinflammation. …”
Get full text

Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaç... by Maaike C Swets, Steven R Kerr, Brian MacKenna, Louis Fisher, Merel van Wijnen, Diederik Brandwagt, Paul W Schenk, Pieter Fraaij, Leonardus G Visser, Sebastian Bacon, Amir Mehrkar, Alistair Nichol, Patrick Twomey, Philippa C Matthews, Malcolm G Semple, Geert H Groeneveld, Ben Goldacre, Iain Jones, J Kenneth Baillie

“…MethodsWe provided hospitals with a simple computational tool to enable laboratories to share nondisclosive summary-level data. …”
Get full text

Utilization of partograph and associated factors among obstetric caregivers in Ethiopia: a systematic review and meta-analysis by Mulat Ayele, Eyob Shitie Lake, Gizachew Yilak, Getinet Kumie, Biruk Beletew Abate, Alemu Birara Zemariam, Befkad Derese Tilahun

“…Cochrane I2 statistics were computed to assess heterogeneity among studies. A subgroup analysis was done based on the study region to minimize underlying heterogeneity. …”
Get full text

Factors Influencing the Development of Metachronous Fractures in Patients with Osteoporotic Vertebral Fractures Treated with Conservative Management or Vertebroplasty by Fernando Ruiz Santiago, Lucía Bueno Caravaca, Francisco Garrido Sanz, Paula María Jiménez Gutiérrez, David Luengo Gómez, Mario Rivera Izquierdo, José Manuel Benítez, Antonio Jesús Láinez Ramos-Bossini

“…<b>Objectives:</b> We aimed to analyze potential predictors for the development of metachronous fractures (MFs) after osteoporotic vertebral fractures (OVFs), with particular focus on radiological variables obtained at initial X-rays and computed tomography (CT) examinations, treatment applied (conservative management [CM] versus percutaneous vertebroplasty [PV]), and fractures located at the thoracolumbar junction (T11-L2). …”
Get full text

Theoretical Study of CO, NO, NO₂, Cl₂, and H₂S Adsorption Interactions with PdO–Graphene Composites for Gas Sensor Applications by Piumantha Samaranayake, Azeez Ahamed, Visal de Silva, Nadeesha Manohari Wickramage, Muhammad Raziq Rahimi Kooh, Roshan Thotagamuge

“…Key parameters such as the adsorption energy, charge transfer, energy gap, density of states, and HOMO–LUMO were computed for each gas molecule on the PdO–graphene composite. …”
Get full text

Anterior Controllable Antedisplacement and Fusion (ACAF) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study by Shuangxi Sun, Yingying Miao, Tao Xu, Kaiqiang Sun, Yijuan Lu, Jingchuan Sun, Jiuyi Sun, Jiangang Shi

“…All patients underwent x‐ray, computed tomography (CT), and magnetic resonance imaging (MRI) before and after surgery. …”
Get full text

FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

“…This ability can aid in the identification of novel genes associated with osteogenic differentiation, which can be utilized in the treatment of osteoporosis. Computational and laboratory evidence indicates that reducing the expression of FOXA1 enhances the process of bone formation in bone marrow-derived mesenchymal stem cells (BMSCs) and may serve as a promising approach to prevent osteoporosis.…”
Get full text

Nursing professionalism and associated factors in Ethiopia: a systematic review and meta-analysis by Moges Tadesse Abebe, Agerie Mengistie Zeleke, Yeshiwas Ayale Ferede, Yosef Aragaw Gonete, Worku Chekol Tassew

“…Publication bias was assessed via funnel plots and Egger’s based regression. We also computed a sensitivity analysis and subgroup analysis by sample size and study period. …”
Get full text

Associations of the Need for Surgery in Emergency Department Patients with Small Bowel Obstructions by Daniel J. Berman, Alexander W. Mahler, Ryan C. Burke, Andrew E. Bennett, Nathan I. Shapiro, Leslie A. Bilello

“…We identified seven independent associations for the decision of surgery: abdominal distension (OR 0.27, 95% CI 0.10–0.62); gastrografin (OR 0.41, 95% CI 0.20–0.81); previous SBO (OR 0.42, 95% CI 0.26–0.66); higher Charlson Comorbidity Index score (OR 0.87, 95% CI 0.80–0.95); nasogastric decompression (OR 2.04, 95% CI 1.25–3.39), initial systolic blood pressure <100 mm Hg (OR 2.65, 95% CI 1.05–6.53); free fluid or volvulus/closed-loop obstruction on computed tomography (OR 7.95, 95% CI 4.25–15.39), with the AUC for the predictive model equaling 0.73. …”
Get full text

Scalar Field Kantowski–Sachs Solutions in Teleparallel <i>F</i>(<i>T</i>) Gravity by Alexandre Landry

“…We find a general formula allowing us to compute all possible new teleparallel <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>F</mi><mo>(</mo><mi>T</mi><mo>)</mo></mrow></semantics></math></inline-formula> solutions applicable for any scalar field potential and ansatz. …”
Get full text