Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…However, common experimental approaches used to study the local characteristics of chromatin have a number of technical limitations that may reduce the reliability of computational identification of genomic regulatory sequences. …”
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Analysis of the structural reliability of communication networks supporting protective switching mechanisms for one protected section and one backup section by K. А. Batenkov, A. B. Fokin

“…The following methods are used: theory of random graphs, matrices, probabilities and computer modeling.Results. The elements of the route, both basic and reserving, are divided into three groups. …”
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CALPHAD-aided synthesis and characterization of an Al–Co–Cr–Fe–Ni–W high-entropy alloy prepared by arc melting and spark plasma sintering by L. Fenocchio, A. Saviot, S. Gambaro, S. Le Gallet, F. Valenza, M.R. Ardigo-Besnard, G. Cacciamani

“…In the present work, the novel Al0.15CoCrFeNiW0.15 High-Entropy Alloy (HEA) has been designed by CALPHAD (CALculation of PHAse Diagrams) computations with the in-house built Genova High-Entropy Alloys (GHEA) database, aiming to a mostly monophasic face-centered cubic (FCC) alloy strengthened by the precipitation of secondary μ phase. …”
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Trimetallic ferrite functionalized by guaninium tartrate ionic liquid (Co0.2Zn0.6Cu0.2Fe2O4-SiO2@[GuaH]+[Tar]2‒[GuaH]+) as a novel inorganic-bioorganic nanostructure to promote aqu... by Zahra Khademi, Kobra Nikoofar, Mansoureh Zahedi-Tabrizi

“…In the theoretical section, the interaction sites between L-tartaric acid and guanine in an aqueous medium were investigated at the B3LYP/6–311++G(d,p) computational level. Additionally, the formation of more stable configurations of dimers and trimers in IL was studied from a thermodynamic point of view.…”
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Towards faster plan adaptation for proton arc therapy using initial treatment plan information by Benjamin Roberfroid, Margerie Huet-Dastarac, Elena Borderías-Villarroel, Rodin Koffeing, John A. Lee, Ana M. Barragán-Montero, Edmond Sterpin

“…Materials and Methods: The proposed workflow transfers spots from initial computed tomography (CT) to the CT of the day, updates energy layers considering the initial pattern, and re-optimizes selected transferred spots based on their initial weights and impact on the objective function.A retrospective study was conducted on five head and neck patients who underwent plan adaptation on a repeated CT. …”
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Engineering the Mechanics and Thermodynamics of Ti₃AlC₂, Hf₃AlC₂, Hf₃GaC₂, (ZrHf)₃AlC₂, and... by Adel Bandar Alruqi

“…Density functional theory within Quantum Espresso module was used in the computations. The Perdew–Burke–Ernzerhof generalised gradient approximation functionals were utilised. …”
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Detectability of Emission from Exoplanet Outflows Calculated by pyTPCI, a New 1D Radiation-hydrodynamic Code by Riley Rosener, Michael Zhang, Jacob L. Bean

“…We use pyTPCI to model seven exoplanets (HD 189733b, HD 209458b, WASP-69b, WASP-107b, TOI-1430b, TOI-560b, and HAT-P-32b) at varying metallicities and compute their emission spectra to investigate their detectability across a variety of spectral lines. …”
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Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms by Jozsef Nagy, Wolfgang Fenz, Stefan Thumfart, Julia Maier, Zoltan Major, Harald Stefanits, Maria Gollwitzer, Johannes Oberndorfer, Nico Stroh, Michael Giretzlehner, Michael Sonnberger, Andreas Gruber, Philip-Rudolf Rauch, Matthias Gmeiner

“…Abstract Accurate rupture risk assessment is essential for optimizing treatment decisions in patients with cerebral aneurysms. While computational fluid dynamics (CFD) has provided critical insights into aneurysmal hemodynamics, most analyses focus on blood flow patterns, neglecting the biomechanical properties of the aneurysm wall. …”
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INFLUENCE OF BEAM HEIGHT-COLUMN WIDTH RATIO ON SEISMIC BEHAVIOR OF RC MOMENT RESISTING FRAMES by A. Khalili, F. Nateghi Alahi

“…Secondly, the effect of the cast-in-situ slab in increasing the negative flexural strength of the beam is often underestimated or ignored, leading to the flexural strength of the columns being less than that of the beams. A series of computational models were created and analyzed in a parametric study to assess the impact of the ratio of beam height to column width on the seismic performance of MRFs. …”
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Gene Selection Based Cancer Classification With Adaptive Optimization Using Deep Learning Architecture by Anju Das, N. Neelima, K. Deepa, Tolga Ozer

“…The abundance of features introduces high dimensionality, contributing to high computational complexity and resource demands. Furthermore, the presence of redundant or highly correlated selected features may lead to multicollinearity issues. …”
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FusionScan: accurate prediction of fusion genes from RNA-Seq data by Pora Kim, Ye Eun Jang, Sanghyuk Lee

“…Simulation test also demonstrated that FusionScan recovered most of true positives without producing an overwhelming number of false-positives regardless of sequencing depth and read length. The computation time was comparable to other leading tools. …”
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Postpandemic Stress Disorder among Health Care Personnel: A Cross-Sectional Study (Silesia, Poland) by Mateusz Grajek, Patryk Szlacheta, Karolina Sobczyk, Karolina Krupa-Kotara, Beata Łabuz-Roszak, Ilona Korzonek-Szlacheta

“…The survey was conducted by indirect survey method using CAWI (computer-assisted web interview). The survey used a questionnaire technique. …”
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Nuclear Data Uncertainty Quantification and Propagation for Safety Analysis of Lead-Cooled Fast Reactors by Ishita Trivedi, Jason Hou, Giacomo Grasso, Kostadin Ivanov, Fausto Franceschini

“…The impact of nuclear data uncertainties based on ENDF/B-VII.0 covariances is quantified on lattice level using the generalized perturbation theory implemented with the Monte Carlo code Serpent and the deterministic code PERSENT of the Argonne Reactor Computational (ARC) suite. The quantities of interest are the main eigenvalue and selected reactivity coefficients such as Doppler, radial expansion, and fuel/clad/coolant density coefficients. …”
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A system approach to the modeling of fungal infections of the wheat leaf by S. V. Nikolaev, U. S. Zubairova, E. S. Skolotneva, E. A. Orlova, D. A. Afonnikov

“…Mathematical models allow computational experiments to make predictions about the risk dynamics of infections in different scenarios of global weather changes. …”
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Deep learning based analysis of G3BP1 protein expression to predict the prognosis of nasopharyngeal carcinoma. by Linshan Zhou, Mu Yang, Jiadi Luo, Hongjing Zang, Songqing Fan, Yuting Zhan

“…<h4>Conclusion</h4>Computational pathology emerges as a transformative tool capable of substantially reducing the burden on pathologists while concurrently enhancing and diagnostic sensitivity and specificity. …”
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On the transitory performance of mixed convective heat and mass transfer around spherical region in the presence of fluctuating streams by Hossam A. Nabwey, Sahar Anwar, Muhammad Ashraf, A.M. Rashad

“…Then these are transformed into more manageable forms via appropriate primitive variable formulation. To obtain the computational solution, the transformed equations are discretized by employing the FDM (Finite Difference Method). …”
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Effective field theory approach to lepton number violating decays K±→ π∓l±l±: short-distance contribution by Yi Liao, Xiao-Dong Ma, Hao-Lin Wang

“…We make a complete analysis on the basis of all dim-9 operators that violate lepton number by two units, and compute their one-loop QCD renormalization effects. …”
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Age-Adjusted D-Dimer in Ruling Out Acute Aortic Syndrome by Dayeon Lee, Yong Won Kim, Tae Youn Kim, Sanghun Lee, Han Ho Do, Jun Seok Seo, Jeong Hun Lee

“…Consecutive adult patients who visited an emergency room between January 2015 and September 2020 and who underwent a D-dimer test and computed tomography angiography for suspected AAS were enrolled. …”
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Classification of benign and malignant solid breast lesions on the ultrasound images based on the textural features: the importance of the perifocal lesion area by А.А. Kolchev, D.V. Pasynkov, I.A. Egoshin, I.V. Kliouchkin, О.О. Pasynkova

“…Subsequently, eight gray-level co-occurrence matrices (GLCM) were constructed for each lesion, and 13 Haralick textural features were calculated for each GLCM. Additionally, we computed the differences in feature values at different spatial shifts and the differences in feature values between the inner and outer areas of the lesion. …”
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Cognitive Deficit-Related Interhemispheric Asynchrony within the Medial Hub of the Default Mode Network Aids in Classifying the Hyperthyroid Patients by Mengmeng Zhi, Zhenghua Hou, Yuqun Zhang, Yingying Yue, Ling Li, Yonggui Yuan

“…Thirty-three hyperthyroid patients and thirty-three matched healthy controls (HCs) were recruited, and they received resting-state functional magnetic resonance imaging (fMRI) scans and neuropsychological evaluation. The VMHC value was computed to reveal the functional coordination between homotopic regions in both groups. …”
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