Basolateral amygdala volume in affective disorders using 7T MRI in vivo by Benedikt Kürzinger, Stephanie Schindler, Martin Meffert, Anja Rosenhahn, Robert Trampel, Robert Turner, Peter Schoenknecht, Peter Schoenknecht, Peter Schoenknecht

“…Quadratic regressions were computed within the MDD group and in relevant subgroups to investigate the presence of a U-shaped relationship between the number of preceding major depressive episodes or the duration of the disease since the first episode and the dependent variables.ResultsDiagnostic groups did not exhibit statistically significant differences in the volumes of the basolateral amygdala (left F (3,75) = 0.66, p >.05; right F (3,76) = 1.80, p >.05), the lateral nucleus (left F (3,75) = 1.22, p >.05; right F (3,76) = 2.30, p >.05)), or the whole amygdala (left F (3,75) = 0.48, p >.05; right F (3,76) = 1.58, p >.05). …”
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Three-dimensional structure of entire hydrated murine hearts at histological resolution by Jasper Frohn, Frederik Böddeker, Marius Reichardt, Hendrik Bruns, Titus Czajka, Amara Khan, Ludovic Broche, Michael Krisch, Alberto Bravin, Frauke Alves, Jana Zschüntzsch, Tim Salditt

“…Our goal is to provide 3d reconstructions of the cardiomyocyte network in entire hydrated murine hearts, and to develop a methodology for quantitative analysis of heart pathologies based on X-ray phase contrast computed tomography (XPCT). We have used XPCT at two beamlines of the extremely brilliant source (EBS) at the European Synchrotron Radiation Facility (ESRF) to scan wild-type murine hearts at high resolution, as well as a series of murine hearts of different pathological models, at reduced resolution and higher throughput. …”
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Elevated miR-221-3p inhibits epithelial–mesenchymal transition and biochemical recurrence of prostate cancer via targeting KPNA2: an evidence-based and knowledge-guided strategy by Dingchao Li, Jingang Jian, Manhong Shi, Zihao Chen, Anguo Zhao, Xuedong Wei, Yuhua Huang, Yalan Chen, Jianquan Hou, Yuxin Lin

“…Finally, a key gene was computationally identified and experimentally validated using cell line and clinical samples through EdU assay, scratch assay, transwell assay, dual-luciferase reporter assay and the epithelial-to-mesenchymal transition (EMT)-related analysis. …”
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PET/CT-derived coronary calcium score may predict cardiac complications in anthracycline-treated patients with lymphoma by Genevieve Douglas, Zoe Loh, Evonne S.Y. Shum, Sze-Ting Lee, Niamh Waters, Garry Hamilton, Geoffrey Chong, Alexandra C. Murphy, Eliza A. Hawkes

“…Our study aimed to evaluate whether CACS obtained from pretreatment positron emission tomography (PET)/computed tomography (CT) scans could stratify cardiac event risk in patients with lymphoma receiving anthracycline-based chemotherapy. …”
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Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities by Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo

“…Medical imaging is critical in modern healthcare for accurately detecting and diagnosing various medical conditions. Advanced computational techniques, particularly preprocessing methods and deep learning models, have demonstrated significant potential for improving medical image analysis. …”
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Bees on the run: Nosema spp. (Microsporidia) in Apis mellifera and related products, Italy by Giovanni Sgroi, Luigi Jacopo D’Auria, Luigi Jacopo D’Auria, Maria Gabriella Lucibelli, Andrea Mancusi, Yolande Thérèsa Rose Proroga, Mauro Esposito, Mauro Esposito, Simona Rea, Daniel Signorelli, Federica Gargano, Nicola D’Alessio, Ranju Ravindran Santhakumari Manoj, Peyman Khademi, Giuseppe Rofrano, Giuseppe Rofrano

“…Whereas all sequences of N. apis were identical to each other, four sequences types of N. ceranae characterized by single nucleotide polymorphisms (SNPs) were identified. The computation of polymorphisms revealed high haplotype diversity (i.e., Hd = 1.000) and low nucleotide diversity (i.e., Pi = 0.00913) of N. ceranae sequence types.DiscussionThis study reveals a high circulation of N. apis and N. ceranae in Southwestern Italy, indicating the need for improved monitoring of these microsporidia to protect bee welfare and bee industry.…”
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Construction and application of a digital twin model for multi-objectiveoptimization of intelligent tape conveyor system by Wei CHEN, Jingzhao LI, Qing SHI, Jichao LIU, Huashun LI

“…Within the physical counterpart, the sweep force in practice is computed by integrating mechanical models, intellectual and experiential knowledge from the engineering field, as well as operational data. …”
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Recombinase-based amplification coupled with lateral flow chromatography for the specific and sensitive detection and identification of Leishmania major in cutaneous leishmaniasis... by Insaf Bel Hadj Ali, Yusr Saadi-Ben Aoun, Imen Khammeri, Hejer Souguir, Emna Harigua-Souiai, Hamed Chouaieb, Ahmed S. Chakroun, Meryem Lemrani, Aicha Kallel, Kalthoum Kallel, Nabil Haddad, Oussaima El Dbouni, Rhea N. Coler, Rhea N. Coler, Rhea N. Coler, Steven G. Reed, Akila Fathallah-Mili, Akila Fathallah-Mili, Ikram Guizani

“…Here, we aimed for a simple and rapid molecular diagnostic test to detect and identify L. major, a predominant CL causal species, which could be prone to become a control tool at the point of care, in endemic areas, using isothermal recombinase DNA amplification (recombinase polymerase amplification, RPA, or recombinase aided amplification, RAA) coupled to detection by the lateral flow (LF) chromatography on a PCRD cassette.MethodsTo develop an L. major species-specific RPA-LF assay, computational analysis of 70 Leishmania DNA targets, identified through bibliography and database searches, selected five targets. …”
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A systematic review of impact of person-centred interventions for serious physical illness in terms of outcomes and costs by Richard Harding, Sridhar Venkatapuram, Alessandra Giusti, Ruwayda Petrus, Liz Gwyther, Lindsay Farrant, I Petersen, Amelia Cook, Kennedy Bashan Nkhoma

“…Some studies reported that interventions had effect in reduction hospital admissions, improving quality of life and reducing costs of care.Technology-based interventions: consisted of mobile phone, mobile app, tablet/computer and video. Although some interventions showed improvements for self-efficacy, hospitalisations and length of stay, quality of life did not improve across most studies.Discussion PCC interventions using self-management have some effects in reducing costs of care and improving quality of life. …”
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ForestAlign: Automatic forest structure-based alignment for multi-view TLS and ALS point clouds by Juan Castorena, L. Turin Dickman, Adam J. Killebrew, James R. Gattiker, Rod Linn, E. Louise Loudermilk

“…This enables advanced computational tools for analysis, planning, and ecosystem management. …”
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Factors influencing the quality of life and mental health of Brazilian Federal Education Network Employees: An epidemiological cross-sectional study by Isabela Fernanda Rodrigues de Oliveira, Nicolli Godoi Pereira, Luís Fernando Monteiro, Leonardo Mateus Teixeira de Rezende, Claudio Andre Barbosa de Lira, Manuel Monfort-Pañego, Woska Pires da Costa, Priscilla Rayanne E. Silva Noll, Matias Noll

“…Conversely, spending 5 h or more using a computer indicated lower QoL in the psychological (p = 0.002) and environmental (p < 0.001) domains. …”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Drug combination efficacy was evaluated by computing combination index scores, and by measuring apoptotic response. …”
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Estimates of disclosure and victimization rates for fishery observers in the maritime workplace by Lacey Jeroue, Lacey Jeroue, Craig Faunce, Andy Kingham, Jaclyn Smith

“…Victimization rates computed from raw survey summary statistics suffer from self-selection bias while rates derived solely from submission of official statements suffer from bias in underreporting. …”
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Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post‐operative dysfunction? by Márton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely, Attila Kovács

“…We decomposed the motion of the ventricle to compute longitudinal ejection fraction (LEF) and radial ejection fraction (REF). …”
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Exploration of alcohol dehydrogenase EutG from Bacillus tropicus as an eco-friendly approach for the degradation of polycyclic aromatic compounds by Muhammad Naveed, Fatima Iqbal, Tariq Aziz, Ayesha Saleem, Tayyab Javed, Mahrukh Afzal, Muhammad Waseem, Metab Alharbi, Thamer H. Albekairi

“…The DNA was extracted from bacterial culture and then the bacterium was identified through 16S rRNA which appeared to be B.tropicus. Then the computational analysis was conducted where the sequence similarity and functional analysis of alcohol dehydrogenase EutG protein from B.tropicus was analyzed through PSI-BLAT and SMART tool, respectively. …”
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Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project by Wasat Mansoor, Stuart Ferguson, Victoria Ross, Denis Talbot

“…Twenty-seven clinicians (10 CoE; 17 non-CoE) participated. Computed tomography of thorax, abdomen, and pelvis was the most commonly reported diagnostic tool (96% of respondents), and bone scans and gallium somatostatin receptor scintigraphy positron emission tomography (SRS PET) were the least commonly reported (30% and 37% of respondents, respectively). …”
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MLL4 regulates postnatal palate growth and midpalatal suture development by Jung-Mi Lee, Hunmin Jung, Bruno de Paula Machado Pasqua, Yungki Park, Qinghuang Tang, Shin Jeon, Shin Jeon, Soo-Kyung Lee, Jae W. Lee, Hyuk-Jae Edward Kwon

“…We generated a novel conditional knockout (cKO) mouse model with tissue-specific deletion of Mll4 in the palatal mesenchyme. Using micro-computed tomography (CT), histological analysis, cell mechanism assays, and gene expression profiling, we examined palate development and growth in the Mll4-cKO mice. …”
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Research on machine vision online monitoring system for egg production and quality in cage environment by Zhenlong Wu, Hengyuan Zhang, Cheng Fang

“…This refined model was implemented on Jetson AGX Orin industrial computer to facilitate real-world applications. To diverse operational needs, two distinct post-processing algorithms were developed: one for counting eggs and detecting abnormalities during robotic patrols, and another for assessing egg quality through fixed video streams, which measured crucial parameters such as egg dimensions and shape indexes. …”
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STUDY OF COMPATIBILITY OF METHODS AND TECHNOLOGIES OF HIGH-LEVEL PROTOCOLS AND ERROR-CORRECTING CODES by Vladyslav Sharov, Olena Nikulina

“…Emerging technologies like quantum computing and artificial intelligence introduce both opportunities and threats, necessitating continuous innovation in these fields. …”
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Long-Term Results of Medical and Surgical Methods for Elimination of the Internal Anal Sphincter Spasm in Chronic Anal Fissure (NCT03855046) by S. I. Achkasov, R. Yu. Khryukin, E. E. Zharkov, A. A. Ponomarenko, O. Yu. Fomenko, N. I. Klopkov, Z. Z. Kamaeva, E. Yu. Lebedeva, K. I. Sagidova

“…The study included 176 patients (73 (41.5 %) men and 103 (58.5 %) women) older than 18 years; randomization into the compared groups was carried out by random number generation in a computer program. Patients, researchers and surgeons were not blinded. …”
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