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20721
A Serious Game to Study Reduced Field of View in Keyhole Surgery: Development and Experimental Study
Published 2025-02-01“…This limited field of view is widely cited as a key limitation of the procedure, and many computational methods have been proposed to overcome it. …”
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20722
A Framework for Analyzing Absorptive Capacity Using Social Network Analysis (Case Study: Sharif University Innovation Ecosystem)
Published 2024-04-01“…Conclusion The absorption capacity model has been identified by extracting the role of each technology field from within and outside the cluster utilizing the social network analysis method by computing the degree of knowledge input, output, and intermediateness. …”
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20723
Investigation of Machinability Characteristics of EDMed Inconel 825 Alloy under Multidimensional Parametric Modeling by Using Holistic Grey-PCA Statistical Models
Published 2022-01-01“…Later, to potentially access the results, the authors integrated the computational Taguchi methodology with dual models which is called as Taguchi-grey relational analysis (T-GRA) and Taguchi-principal component analysis (T-PCA). …”
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20724
Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe
Published 2025-02-01“…Programmatic costs will be ascertained throughout the study and incremental cost-effectiveness ratios will be computed for each arm.Ethics and dissemination The RCT has been approved by the University of California, San Francisco (UCSF) (Human Research Protection Program; Protocol Number 23-40642), and the study has been approved by the National Health Sciences Research Committee (NHSRC; Protocol Number 24/05/4431) in Malawi. …”
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20725
The Application of Three-dimensional Shear Wave Elastography in the Detection of Inguinal Lymph Node Metastasis in Gynecological Malignancies
Published 2025-01-01“…However, conventional imaging techniques, such as ultrasound and computed tomography (CT), demonstrate limited accuracy in determining the nature of lymph nodes. …”
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20726
Prevalence and Determinants of Home Delivery among Women with Easy Access to Health Facilities in Sub-Saharan African Countries: A Multi-level Mixed Effect Analysis
Published 2025-01-01“…The adjusted odds ratio at the 95% confidence interval (Cl) was computed to assess the strength and significance of the association between explanatory and outcome variables. …”
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20727
Clinicopathological Analysis and Surgical Outcome of Eyelid Malignancies: A Study of 332 Cases
Published 2022-01-01“…All patients were managed by surgical excision with tumor-free margins verified on histopathology, either the frozen section or excision biopsy with 2–3 mm microscopic view of normal tissue followed by eyelid reconstruction. Computer-based statistical software SPSS was used for the analysis, and an appropriate test of significance (chi-square) was used for the statistical analysis. …”
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20728
Indirect contacts between Danish pig farms – what are the frequencies and risk-reducing measures, and how can they be used in simulation models?
Published 2025-01-01“…Conclusion Since the inclusion of indirect contacts in disease spread models relies on valid data, the present study provided valuable data regarding the frequencies and biosecurity measures of indirect contacts between Danish pig herds, which may be useful in the parametrization of computational epidemiological models.…”
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20729
Artificial Intelligence–Powered Training Database for Clinical Thinking: App Development Study
Published 2025-01-01“… Abstract BackgroundWith the development of artificial intelligence (AI),ntered the era of intelligent medicine ObjectiveThis study aimed to introduce an app named “XueYiKu,” which includes consultations, physical examinations, auxiliary examinations, and diagnosis, incorporating AI and actual complete hospital medical records to build an online-learning platform using human-computer interaction. MethodsThe “XueYiKu” app was designed as a contactless, self-service, trial-and-error system application based on actual complete hospital medical records and natural language processing technology to comprehensively assess the “clinical competence” of residents at different stages. …”
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20730
A basis water quality monitoring plan for rehabilitation and protection
Published 2022-04-01“…E. coli was also detected in water samples collected in all sampling stations. The computed water quality index of 39.02 described water as poor, always impaired, and threatened by the surrounding environment. …”
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20731
Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank
Published 2025-01-01“…A UPF metabolomic signature was computed as a weighted sum of UPF-related metabolites, using elastic net coefficients as weights. …”
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20732
Pharmacognostic analysis and antimalarial evaluation of quercetin in Ilex umbellulata bark using HPTLC, in vitro screening, molecular docking, and network pharmacology
Published 2025-02-01“…In this study, we aim to develop the missing pharmacognostic parameters with modern analytical techniques and carry out multi-step computational studies to study the antimalarial potential of I. umbellulata. …”
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20733
Thermal properties and non-bonded interactions in human PMP2 variants: A molecular dynamics study
Published 2025-01-01“…Many studies on this disease have been conducted, including clinical as well as computational, but no effective medical cure has yet been found. …”
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20734
A density functional theory investigation of the substituent effect on acyclovir and guanine derivatives for applications on energetic materials
Published 2024-12-01“…Several molecular properties were computed, including the chemical reactivity, the heat of formation and the detonation velocities and pressures using semiempirical equations. …”
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20735
Advances in the pilot point inverse method: Où En Sommes-Nous maintenant?
Published 2023-01-01“…., 2000], but with a particular focus on the incredible adoption and advancement of de Marsily’s PPM and related inverse techniques over the last twenty years in the field of predictive groundwater modeling.Much has been written about the vast array of inverse techniques developed by researchers and practitioners since the 1960s. de Marsily’s PPM, like many methods developed in the late 70s and early 80s, structured its approach to parameterization to overcome many of the challenges of applying inverse methods to real world problems, namely, limited head and transmissivity data relative to the number of unknowns to be estimated, measurement errors, inferred covariance structures of the state variables, and limited computational resources. While inversion research continues, only de Marsily’s PPM has achieved wide-spread adoption within the groundwater modeling community.The reasons for the popularity of the PPM are many but none more important than its adoption by John Doherty’s PEST inversion software in the early 2000s [Doherty, 2003]. …”
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20736
Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study
Published 2025-01-01“…Causal effects were estimated using the inverse variance weighting (IVW) method, while the Summary Data-based Mendelian Randomization (SMR) method, leveraging pooled data, was applied to compute effect estimates. These estimates were further refined through various approaches including MR-Egger, the weighted median method, simple and weighted models, and leave-one-out analyses to conduct sensitivity analyses.ResultThe analytical outcomes utilizing the IVW method indicated that inhibitors of HMGCR were correlated with an elevated risk of developing gout (IVW: OR [95%CI] = 1.25 [1.03, 1.46], p=0.0436), while PCSK9 inhibitors were linked to heightened levels of urate (IVW: OR [95%CI] = 1.06 [1.01,1.10], p=0.0167). …”
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20737
SARS-CoV2 pneumonia patients admitted to the ICU: Analysis according to clinical and biological parameters and the extent of lung parenchymal lesions on chest CT scan, a monocentri...
Published 2024-01-01“…<h4>Objective</h4>The objectives of this study were to measure the prognostic value of the extent of lung parenchymal lesions on computed tomography (CT) and of several coagulation and inflammatory biomarkers, and to explore the characteristics of the patients depending on the extent of lung parenchymal lesions.…”
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20738
AICpred: Machine Learning-Based Prediction of Potential Anti-Inflammatory Compounds Targeting TLR4-MyD88 Binding Mechanism
Published 2025-01-01“…Additionally, compounds known to inhibit TLR4, including TAK-242 (Resatorvid) and benzisothiazole derivative (M62812), were predicted as bioactive agents within the applicability domain with probabilities above 0.80. Computationally inferred compounds using AICpred can be explored as potential starting skeletons for therapeutic agents against hyperinflammation. …”
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20739
Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaç...
Published 2024-12-01“…MethodsWe provided hospitals with a simple computational tool to enable laboratories to share nondisclosive summary-level data. …”
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20740
Utilization of partograph and associated factors among obstetric caregivers in Ethiopia: a systematic review and meta-analysis
Published 2025-01-01“…Cochrane I2 statistics were computed to assess heterogeneity among studies. A subgroup analysis was done based on the study region to minimize underlying heterogeneity. …”
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