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3241
Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study
Published 2025-01-01“…Gaia Zucca,1 Barbara Vigani,1 Caterina Valentino,1 Marco Ruggeri,1 Nicoletta Marchesi,1 Alessia Pascale,1 Giulia Giovilli,2 Lorenzo Malavasi,2 Giuseppina Sandri,1 Silvia Rossi1 1Department of Drug Sciences, University of Pavia, Pavia, 27100, Italy; 2Department of Chemistry and INSTM, University of Pavia, Pavia, 27100, ItalyCorrespondence: Silvia Rossi; Barbara Vigani, Department of Drug Sciences, University of Pavia, Via Taramelli 12, Pavia, 27100, Italy, Email silvia.rossi@unipv.it; barbara.vigani@unipv.itPurpose: The main purpose of the study was the formulation development of nanogels (NHs) composed of chondroitin sulfate (CS) and low molecular weight chitosan (lCH), loaded with a naringenin-β-cyclodextrin complex (NAR/β-CD), as a potential treatment for early-stage diabetic retinopathy.Methods: Different formulations of NHs were prepared by varying polymer concentration, lCH ratio, and pH and, then, characterized for particle size, zeta potential, particle concentration (particles/mL) and morphology. …”
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3242
Investigating the preventive effects of pulsed electromagnetic fields on glucocorticoid-induced osteoporosis in rats
Published 2025-01-01“…A total of seventy-two adult male Wistar rats composed the experimental group and were subsequently assigned to three groups for treatment. (1) On the first day (day 0), 24 rats in the PEMF group were intravenously injected with lipopolysaccharide (LPS) at a concentration of 10 μg/kg. …”
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3243
Chemical analysis of buffalo meat in a self-consumption system in northeastern of Argentina
Published 2023-11-01“…Animals were raised on natural fields, with access to self-consumption hoppers to supply food composed of alfalfa bales, broken and whole corn, and soybean pellets with a consumption of 1.5% of live weight. …”
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3244
Le tourisme romantique d’avant mariage : un marché fructueux dans la mise en tourisme d’une destination ? Exemple de la station climatique Dalat – Vietnam
Published 2023-12-01“…Bien que le mariage ait lieu en plusieurs fois, chaque fois se compose simplement d’une cérémonie, suivie d’une réception. …”
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3245
Dietary supplementation of composite feed additive reduces enteric methane production and enhances feed efficiency, milk production and immunity in Murrah buffalo (Bubalus bubalis)
Published 2023-11-01“…The feed supplement was developed at the institute, composed of an ideal combination of methane inhibitors, alternate hydrogen sinks, and some rumen-stimulating agents (Indian Patent Grant No. 388717 dated 08.02.2022) and its efficacy examined through a series of in vitro experiments. …”
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3246
Production of Biogas from Bio-Degradable Municipal Solid Waste – A Way of Resource Recovery.
Published 2023“…According to recent study done on the characterisation of MSW in Kabale Municipality, 100kgs of MSW was considered for the study. 87% of the total this MSW composed of biodegradable component. These included food wastes, garden trimmings, paper waste, wood wastes and other biodegradable components having 0.5%, 94.2%, 2.3%, 0.3% and 2.7% respectively of the total biodegradable components. …”
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3247
Dépôts et pratiques symboliques dans l’établissement aristocratique gaulois de Varennes-sur-Seine, la Justice (Seine-et-Marne)
Published 2021-12-01“…Though these deposits are composed of some of the most commonplace items (fauna, ceramics, objects of adornment, metallic instruments, coins, etc.), the interpretation of such evidence often remains nonetheless ambiguous. …”
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3248
Analysis of drought and extreme precipitation events in Thailand: trends, climate modeling, and implications for climate change adaptation
Published 2025-02-01“…The climate indices used were Consecutive Dry Days (CDD), Maximum Number of Consecutive Summer Days (CSU), Consecutive Wet Days (CWD), Warm Spell Duration Index (WSDI), and Maximum Number of Consecutive Wet Days (WW) derived from simulations of an ensemble composed of six models from the Intergovernmental Panel on Climate Change (IPCC) via the Coupled Model Intercomparison Project Phase 6 (CMIP6) using Artificial Neural Networks (ANN) with the backpropagation method. …”
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3249
RETRACTED ARTICLE: Synthesis of silver nanoparticles using Plantago lanceolata extract and assessing their antibacterial and antioxidant activities
Published 2021-10-01“…The EDX spectrum revealed that the Ag. NPs were composed of 54.87% Ag with 20 nm size as identified by SEM and TEM. …”
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3250
VACCIMEL, an allogeneic melanoma vaccine, efficiently triggers T cell immune responses against neoantigens and alloantigens, as well as against tumor-associated antigens
Published 2025-01-01“…VACCIMEL is a therapeutic cancer vaccine composed of four irradiated allogeneic human melanoma cell lines rationally selected to cover a wide range of melanoma tumor-associated antigens (TAA). …”
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3251
A European aerosol phenomenology – 9: Light absorption properties of carbonaceous aerosol particles across surface Europe
Published 2025-01-01“…Carbonaceous aerosols (CA), composed of black carbon (BC) and organic matter (OM), significantly impact the climate. …”
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3252
Identification of Plasma Absorbed Components of Qingxin Zishen Prescription by UPLC-Q-TOF MS
Published 2025-01-01“…Then, chromatographic separation of the plasma samples was performed on an Agilent ZORBAX SB C18 column (4.6 mm×100 mm, 1.8 µm) using a gradient elution with a mobile phase composed of 0.1% formic acid aqueous solution (A) and methanol-acetonitrile (1:1, V/V, B) prior to MS analysis. …”
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3253
Probing the Dual Role of Ca<sup>2+</sup> in the <i>Allochromatium tepidum</i> LH1–RC Complex by Constructing and Analyzing Ca<sup>2+</sup>-Bound and Ca<sup>2+</sup>-Free LH1 Comple...
Published 2025-01-01“…Here, we use the purple bacterium <i>Rhodospirillum rubrum</i> strain H2 as a host to express Ca<sup>2+</sup>-bound and Ca<sup>2+</sup>-free <i>Alc. tepidum</i> LH1-only complexes composed of α- and β-polypeptides that either contain or lack the calcium-binding motif WxxDxI; purified preparations of each complex were then used to test how Ca<sup>2+</sup> affects their thermostability and spectral features. …”
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3254
Feasibility of mango by-products and biogas solid residue aerobic co-composting at different C/N ratios
Published 2023-10-01“…Purpose: Co-composting of mango by-products and biogas solid residue eliminates some shortcomings of composting these wastes separately. Specifically, co-composing solves the problem of the low pH values in mango by-products while enhances biodegradable organic matter of biogas solid residues. …”
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3255
Le port antique de Chelles (Seine-et-Marne) : une course après la rivière
Published 2020-12-01“…-Phase 1, around 35 BC: a riverbank fastening set-up, composed of branches and logging waste, several wooden posts, and possibly included a light, make-shift wharf structure, was installed in the hopes of stabilizing the bank. …”
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3256
Effect of different diets on the fatty acid compo- sition of buffalo bulk milk
Published 2023-11-01“…They were provided as a total mixed ratio where different components (about 3% in dry matter of total ration) were added to the essential diet for each group: basic diet (B) was composed of maize silages, alfalfa hay, corn grain, and soybean as concentrates, the second diet contained linseed as an additional constituent to B (L), another brewer’s spent grain (T), additional alfalfa and mixed hay (H), additional corn grain (M), grass (G); other farms included in B diet both grass and cottonseed (CG), grass and linseed (GL) or grass and brewer’s spent grain (TG) and at last grass linseed and brewer’s spent grain (LTG). …”
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3257
A relay race of ESCRT-III paralogs drives cell division in a hyperthermophilic archaeon
Published 2025-02-01“…Archaea of the order Sulfolobales divide using a simpler version of the eukaryotic endosomal sorting complexes required for transport (ESCRT) machinery, composed of three ESCRT-III homologs (ESCRT-III, -III-1, and -III-2), AAA+ ATPase Vps4 and an archaea-specific component CdvA. …”
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3258
Nutritional strategies for laying hens to address environmental challenges by reducing the nitrogen excretion
Published 2024-01-01“…For that, a 6-week trial was developed, with 90 Lohmann Brown laying hens aged 51 weeks, raised in digestibility cages, divided into three groups with 30 hens each. The diets were composed as follows: a control group fed with 17.50% crude protein (CON), an experimental group with a reduced CP level of 15.50% (RPL), and a similar reduced CP group supplemented with 0.5% CSP (RPC) as tannin additive. …”
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3259
Feminization of Maroon Clownfish (<I>Amphiprion biaculeatus<I/>, Bloch 1790) with 17β-Estradiol Hormonal Induction
Published 2023-08-01“…These treatments were applied with three replications. Five fish composed of α-fish, β-fish, and three γ-fish were reared in each aquarium for 90 days with a flowing water system. …”
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3260
Genetic diversity and population structure studies of West African sweetpotato [Ipomoea batatas (L.) Lam] collection using DArTseq.
Published 2025-01-01“…Population structure analysis divided the 271 accessions into four populations (population 1 was characterised by a mixture of accessions from all countries; population 2, mostly comprised of Nigerian breeding lines; population 3 contained exclusively landraces from Benin; and population 4 was composed by only landraces from West African countries) at K = 4, and analysis of molecular variance (AMOVA) based on PhiPT values showed that most of the variation was explained when accessions were categorized based on population structure at K = 4 (25.25%) and based on cluster analysis (19.43%). …”
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