Protective Efficacy of Decreasing Antigen Doses of a <i>Chlamydia abortus</i> Subcellular Vaccine Against Ovine Enzootic Abortion in a Pregnant Sheep Challenge Model by Morag Livingstone, Kevin Aitchison, Javier Palarea-Albaladejo, Francesco Ciampi, Clare Underwood, Antonia Paladino, Francesca Chianini, Gary Entrican, Sean Ranjan Wattegedera, David Longbottom

“…Recently, we have described the development of a new COMC (chlamydial outer membrane complex) vaccine based on a detergent-extracted outer membrane protein preparation of the pathogen, which can be delivered in a single inoculation and is both efficacious and safe. …”
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Difficult choledocholithiasis – result of overdue surgical treatment of gallstone disease by S. G. Shapovalyants, T. B. Ardasenov, A. G. Pankov, S. A. Budzinsky, V. S. Veselova

“…Part of patients (84) received conservative therapy for biliary colic and complications of GSD, abandoning of operative treatment resulted in, first, development of severe complication – choledocholithiasis, second, development of unfavorable anatomical conditions for its noninvasive resolution.Conclusion. Complex anatomical conditions in patients with choledocholithiasis basically develop as a result of overdue surgical treatment of gallstone disease. …”
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The study of organelle DNA variability in alloplasmic barley lines in the NGS era by M. G. Siniauskaya, A. M. Makarevich, I. M. Goloenko, V. S. Pankratov, A. D. Liaudanski, N. G. Danilenko, N. V. Lukhanina, A. M. Shimkevich, O. G. Davydenko

“…Seven of the SNPs were located in the genes of the Ndh complex. The nonsynonymous changes of nucleotides were detected in the matK, rpoCI, ndhK, ndhG and infA genes. …”
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The ENaC taste receptor’s perceived mechanism of mushroom salty peptides revealed by molecular interaction analysis by Wen Li, Wanchao Chen, Di Wu, Zhong Zhang, Peng Liu, Zhengpeng Li, Yan Yang

“…The salty peptide-ENaC receptor binding complex was stable around 0.3 nm, and the tight and multisite binding was the main reason the ENaC receptor sensed the salty peptide, enabling it to exert its taste effect. …”
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Effect of chemical composition and T6 heat treatment on the mechanical properties and fracture behaviour of Al-Si alloys for IC engine components by Vuksanović D., Asanović V., Šćepanović J., Radonjić D.

“…The microstructural examinations of Al-Si alloys intended to manufacture IC engine components revealed a complex phase composition in all the samples. The polyhedral crystals of primary silicon were detected in the Al-12.5Si alloy, besides the α-Al phase, eutectic silicon, and several intermetallic phases, identified in the cast samples of both alloys. …”
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Pilot study: Initial investigation suggests differences in EMT-associated gene expression in breast tumor regions by Kylie L. King, Hamed Abdollahi, Zoe Dinkel, Alannah Akins, Homayoun Valafar, Heather Dunn

“…ML enables the analysis of complex datasets and the extraction of useful information from small datasets. …”
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SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

“…Objective: AMP-activated protein kinase (AMPK) is a heterotrimer complex consisting of a catalytic α subunit (α1, α2) with a serine/threonine kinase domain, and two regulatory subunits, β (β1, β2) and γ (γ1, γ2, γ3), encoded by different genes. …”
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Predicting hydropower generation: A comparative analysis of Machine learning models and optimization algorithms for enhanced forecasting accuracy and operational efficiency by Chunyang Wang, Chao Li, Yudong Feng, Shoufeng Wang

“…The framework is designed to tackle challenges in the prediction of hydropower generation by effectively managing complex, multivariate data. Between the tested models, the integrated CatBoost- hunger Games search model brings out exceptional predictive accuracy, with a Coefficient of Determination of 0.9075 and a Root Mean Square Error of 45.2130 during testing. …”
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Archaeological Site Detection: Latest Results from a Deep Learning Based Europe Wide Hillfort Search by Jürgen Landauer, Simon Maddison, Giacomo Fontana, Axel G. Posluschny

“…This research tackles the complexities of large-scale archaeological site detection by integrating Artificial Intelligence (AI) with LiDAR data, focusing on hillforts across diverse European landscapes. …”
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Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea by Sung Hoon Jeong, Seong Min Chun, Miji Kim, Ye Seol Lee, Jisun Kim, Ja-Ho Leigh, Yoon-Hee Choi

“…Conclusion BCRL occurrence is an after-effect of complex breast cancer treatments, and the risk may vary depending on the treatment method, including Surg, chemo, and radio. …”
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Technologically-Treated Polyclonal Affinity-Purified Antibodies to the Tumor Necrosis Factor-α, Brain Specific S-100 Protein and Histamine in Treatment of Functional Dyspepsia: Res... by Yu. O. Shulpekova, I. V. Maev, V. B. Grinevich, I. B. Khlynov, Yu. G. Shvarts, V. T. Ivashkin

“…The aim of the study was to evaluate the efficacy and safety of Kolofort® (a complex medicine containing technologically processed forms of antibodies to S-100 protein, tumor necrosis factor-α and histamine) in the management of functional dyspepsia (FD) in outpatient clinical practice.Methods: Outpatients (N = 309) at the age of 18–45 in whom FD was diagnosed according to the Rome IV criteria were enrolled in a multicenter, double-blind, placebo-controlled, randomized clinical trial. …”
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A Deep Learning-Based Approach for the Detection of Various Internet of Things Intrusion Attacks Through Optical Networks by Nouman Imtiaz, Abdul Wahid, Syed Zain Ul Abideen, Mian Muhammad Kamal, Nabila Sehito, Salahuddin Khan, Bal S. Virdee, Lida Kouhalvandi, Mohammad Alibakhshikenari

“…Leveraging advanced deep learning methods, specifically Convolutional Neural Networks (CNNs), XIoT analyzes spectrogram images transformed from IoT network traffic data to detect subtle and complex attack patterns. Unlike traditional approaches, XIoT emphasizes interpretability by integrating explainable AI mechanisms, enabling cybersecurity analysts to understand and trust its predictions. …”
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Bibliometric and visual analysis in the field of electroacupuncture’s analgesia and regulation on negative emotion from 2014 to 2024 by Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Junfan Fang, Jianqiao Fang, Jianqiao Fang, Junying Du, Junying Du

“…The findings provide a roadmap for enhancing the therapeutic applications of EA and underscore its potential in managing complex conditions involving both physical and emotional components.…”
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Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps by Colinet, Dominique, Cavigliasso, Fanny, Leobold, Matthieu, Pichon, Apolline, Urbach, Serge, Cazes, Dominique, Poullet, Marine, Belghazi, Maya, Volkoff, Anne-Nathalie, Drezen, Jean-Michel, Gatti, Jean-Luc, Poirié, Marylène

“…Animal venoms and other protein-based secretions that perform a variety of functions, from predation to defense, are highly complex cocktails of bioactive compounds. Gene duplication, accompanied by modification of the expression and/or function of one of the duplicates under the action of positive selection, followed by further duplication to produce multigene families of toxins is a well-documented process in venomous animals. …”
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Bacterial communities as bioindicators of climate change in freshwater ecosystems: Tank bromeliads as model systems by Daniel Di Pace Soares Penna, Gustavo Quevedo Romero, Mark P. Nessel, Angélica L. González, Valéria Maia Oliveira

“…Tank bromeliads, functioning as natural microcosms, offer a valuable model for studying tropical ecosystems. These plants host complex communities, including microorganisms, which may serve as bioindicators of climate change due to their adaptability and ubiquity. …”
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Use of virtual reality to remotely train healthcare professionals in paediatric emergency tracheostomy skills: protocol for a multi-centre, non-inferiority educational intervention... by Jonathan R. Abbas, Noorulanne Younis, Emily Johnstone, Azita Rajai, Rachel Isba, Antony Payton, Brendan A. McGrath, Neil Tolley, Iain A. Bruce

“…Abstract Background The insertion of a tracheostomy is an established technique used to wean patients off ventilatory support, manage secretions in complex conditions, and as a potentially life-saving procedure to bypass upper airway obstruction. …”
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Using a region-specific ice-nucleating particle parameterization improves the representation of Arctic clouds in a global climate model by A. B. Gjelsvik, R. O. David, T. Carlsen, F. Hellmuth, S. Hofer, Z. McGraw, Z. McGraw, H. Sodemann, H. Sodemann, T. Storelvmo, T. Storelvmo

“…Ice-nucleating particles (INPs) are necessary for primary cloud ice formation at temperatures above approximately <span class="inline-formula">−</span>38 °C and thus significantly affect cloud phase and cloud radiative effect (CRE). Due to their complex and insufficiently understood variability, INPs constitute an important modelling challenge, especially in remote regions with few observations, such as the Arctic. …”
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Experimental Investigation of Chemical Flooding Using Nanoparticles and Polymer on Displacement of Crude Oil for Enhanced Oil Recovery by Imran Akbar, Hongtao Zhou, Wei Liu, Muhammad Usman Tahir, Asadullah Memon, Ubedullah Ansari, Fengzhang Lv

“…Some reservoirs are very complex and require advanced enhanced oil recovery (EOR) techniques containing new materials and additives in order to produce maximum oil in economic and environmental friendly manners. …”
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The Lived Experience of Suffering by Nigerian Female Breast Cancer Survivors: A Phenomenological Perspective by Chinomso Ugochukwu Nwozichi PhD, RN, CMSRN, OCN, FAAN, Margaret Olutosin Ojewale PhD, RN, Omolabake Salako BSN, RN, Deliverance Brotobor MSc, RN, Elizabeth Olaogun MSc, RN

“…The findings highlight the complex nature of suffering among breast cancer survivors in Nigeria, underscoring the need for comprehensive survivorship care that addresses physical, psychosocial, and spiritual dimensions. …”
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Hybrid metaheuristic artificial neural networks for stock price prediction considering efficient market hypothesis by Milad Shahvaroughi Farahani, Hamed Farrokhi-Asl, Saeed Rahimian

“…However, predicting stock price trends is a complex task due to the multitude of influencing factors. …”
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