Influences of non-uniformly distributed forming loads on deformation sequence and texture evolution in tailor heat treated Al6014 blanks by Nan Xiang, Meng-han Yang, Wan-ting Sun, Tao Huang, Hai-rui Zhang, Peng-yi Wang, Fei-yang Cheng

“…Tailor heat treatment (THT)-induced local material softening of precipitation-hardening alloy sheet can provide a simplified process routine for the manufacture of shell components with regional complex shape. Nevertheless, the challenges are also introduced, such as excessive plastic deformation and increased risk of rupture in the softened region, leading to diminished formability of the sheet metal. …”
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Revisiting Near-infrared Features of Kilonovae: The Importance of Gadolinium by Salma Rahmouni, Masaomi Tanaka, Nanae Domoto, Daiji Kato, Kenta Hotokezaka, Wako Aoki, Teruyuki Hirano, Takayuki Kotani, Masayuki Kuzuhara, Motohide Tamura

“…This is due to their complex structures leading to many low-lying energy levels, which results in strong transitions in the near-infrared range. …”
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Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis by BU Jialiang, SHEN Lin, MENG Yuan, PIAO Yingshi

“…Among the cellular components, receptor complex and membrane rafts accounted for a large proportion. …”
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Elevated Serum Interleukin-23 Levels in Patients with Oral and Cutaneous Lichen Planus by Maryam Mardani, Hossein Mofidi, Ladan Dastgheib, Sara Ranjbar, Nasrin Hamidizadeh

“…Based on the evidence, a complex cytokine network plays a crucial role in lichen planus pathogenesis. …”
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Multi-objective optimization of SUS430C steel turning process using hybrid machine learning and evolutionary algorithm approach by Nguyen Van-Canh, Nguyen Anh-Thang, Pham Ngoc-Linh, Nguyen Thuy-Duong

“…The findings underscore the effectiveness of the hybrid XGBoost-NSGA-II approach in solving complex manufacturing optimization problems and serve as a foundation for future applications in sustainable and efficient machining practices.…”
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Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series by Yuan Ding, Yuan Ding, Ming Cheng, Ming Cheng, Bingyan Cao, Bingyan Cao, Min Liu, Min Liu, Xuyun Hu, Xuyun Hu, Di Wu, Di Wu, Di Wu

“…BackgroundApparent Mineralocorticoid Excess (AME) is a rare autosomal recessive disorder, characterized by a notably complex diagnostic process. To date, the majority of documented cases have been presented as individual case reports. …”
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In silico design of a multi-epitope vaccine against Mycobacterium avium subspecies paratuberculosis by Weiqi Guo, Weiqi Guo, Xinyu Wang, Jiangang Hu, Beibei Zhang, Luru Zhao, Luru Zhao, Guangdong Zhang, Jingjing Qi, Zuzhang Wei, Yanqing Bao, Mingxing Tian, Shaohui Wang

“…Both the vaccine candidate and the vaccine-TLR4 complex demonstrated considerable stability in molecular dynamics simulations. …”
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Blood proteomics and multimodal risk profiling of human volunteers after incision injury: A translational study for advancing personalized pain management after surgery by Daniel Segelcke, Julia R. Sondermann, Christin Kappert, Bruno Pradier, Dennis Görlich, Manfred Fobker, Jan Vollert, Peter K. Zahn, Manuela Schmidt, Esther M. Pogatzki-Zahn

“…Thus, prognostic prediction models that include bio-psycho-social and physiological factors in line with the complex nature of chronic pain would be urgently required. …”
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Harmonizing the past: EEG-based brain network unveil modality-specific mechanisms of nostalgia by Hu Shuxiang, Hu Shuxiang, Liu Ying, Liu Ying, Yue Qizong, Yue Qizong, Zhao Huan, Zhao Huan, Zheng Maoping, Zheng Maoping

“…IntroductionNostalgia is a complex emotional experience involving fond memories of the past and mild sadness, characterized by positive emotions associated with reflecting on previous events. …”
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Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography by Pierre-Maxime Lévêque, Pierre Zéboulon, Emmanuelle Brasnu, Christophe Baudouin, Antoine Labbé

“…Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. …”
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Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens by Larry E. Morrison, Tania M. Larrinaga, Brian D. Kelly, Mark R. Lefever, Rachel C. Beck, Daniel R. Bauer

“…<b>Conclusions:</b> Simultaneous staining and detection, as described here, provides the pathologist a means to evaluate complex multiplexed assays, while seated at the microscope, with the added multispectral imaging capability to support digital pathology and artificial intelligence workflows of the future.…”
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Exploring the operator experience in automated shuttles: Fatigue, attention, and gaze behaviour by Christer Ahlström, My Weidel, Anna Sjörs Dahlman, Ashleigh Filtness, Anna Anund

“…Study A used a controlled experimental methodology to compare fatigue and gaze behaviour at complex road sections during the first and last hours of one shift. …”
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The Overaction of the Inferior Oblique Muscle and Associated Vertical Strabismus: Prevalence, Etiology and Diagnosis by Masoud Khorrami-Nejad, Huda Karim, Wisam Hatem, Mustafa Abdullah, Ali Gheibi, Mohammad Ghasemi Boromand

“…The mechanism of action of the IO muscle is complex and varies with the globe's position during contraction. …”
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Lipid Coating Modulates Effects of Nanoceria on Oxidative Metabolism in Human Embryonic Lung Fibroblasts: A Case of Cardiolipin by Elena V. Proskurnina, Madina M. Sozarukova, Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Natalia N. Veiko, Maria A. Teplonogova, Vladimir P. Saprykin, Vladimir K. Ivanov, Svetlana V. Kostyuk

“…Lipid modifiers of the nanoparticle surface change their biochemical properties and bioavailability. Complexes with lipids can be formed upon contact of the nanoparticles with the membrane. …”
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Volumetric alterations in auditory and visual subcortical nuclei following perinatal deafness in felines by Alessandra Sacco, Stephen G. Gordon, Stephen G. Lomber

“…In the auditory pathway, significant bilateral volumetric reductions were revealed within the lower-level structures (cochlear nucleus, superior olivary complex, and inferior colliculus), alongside a shrinkage of solely the left medial geniculate body. …”
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B-phosphatidylethanol testing to identify hazardous alcohol use in primary health care—a game changer and a challenge for general practitioners: a qualitative study by Åsa Steensland, Anna Segernäs, Mårten Larsson, Andrea Johansson Capusan, Lisa Kastbom

“…This study aimed to explore general practitioners’ (GPs’) experiences and perceptions of using B-Phosphatidylethanol (PEth), a specific quantitative biomarker for alcohol use, in their clinical work with patient consultations and treatment follow-up in Swedish PHC.Design, participants, and setting Individual interviews were conducted with GPs and resident GPs (n 20) in Swedish PHC and analysed using qualitative content analysis.Findings The overarching theme PEth testing in primary health care—a game changer and a challenge illustrated that PEth testing has improved the prerequisites for the GP-patient interaction while making it more complex. Four categories underpinned this theme: Comprehending the context, describing the challenges in the GP-patient interaction when hazardous alcohol use or AUD was suspected; Getting the pieces in place, illustrating the struggle of integrating PEth testing into clinical practice and how it diminished the role of alcohol history taking; The challenges and facilitators of the conversation, comprising both the difficulties in informing about PEth testing and the positive impact on the interaction, and Considerations based on the PEth test results, emphasising the consequences of elevated PEth test results and their influence on physicians’ motivation to using PEth.Conclusions PEth is an important tool in the identification of hazardous alcohol use. …”
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Treating self-harm behaviors in prisons: implementation of the STEPPS program by Rosa Lorente-Català, Irene Jaén, Xavier Buscà-Huertas, Berta Framis, Azucena García-Palacios

“…However, significant challenges arise when implementing evidence-based programs within this complex setting. Despite these hurdles, the Systems Training for Emotional Predictability and Problem Solving (STEPPS) program has garnered recognition, notably in the United States, for its efficacy in tackling such issues. …”
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Multi-Sensor-Fusion Approach for a Data-Science-Oriented Preventive Health Management System: Concept and Development of a Decentralized Data Collection Approach for Heterogeneous... by Sebastian Neubert, André Geißler, Thomas Roddelkopf, Regina Stoll, Karl-Heinz Sandmann, Julius Neumann, Kerstin Thurow

“…The developed system can be easily adapted to changing health-care applications by using different sensor combinations. The complex processing for data analysis can be supported and intervention measures can be provided.…”
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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

“…Inflammasomes, the multiprotein complexes that launch the innate immune response, emerge as important mediators in the pathogenesis of HCC. …”
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Development of an Augmented Reality-Based Practicum E-Module Integrated with Local Wisdom of Salak Fruit by Heni Mulyani Pohan, Adi Syaputra, Fatma Suryani Harahap, Dinda Yunita, Rabiyatul Adawiyah Siregar, Anouar Ben Mabrouk

“…E-modules that incorporate AR can provide three-dimensional visualizations, making complex topics more accessible and engaging. This study aims to develop and validate practical e-modules using AR technology to enhance students' spatial intelligence while incorporating local wisdom from Padangsidimpuan. …”
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