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19461
Role of HLA alleles polymorphism in systemic lupus erythematosus: A prospective study from North India
Published 2023-07-01“…Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder and has complex etiopathogenesis. The most appropriate hypothesis states that genetic susceptibility in the presence of environmental risk factors predisposes to SLE. …”
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19462
Progress in plant genome sequencing: research directions
Published 2019-02-01“…Since a high coverage and resolution of a genome sequence is not enough to detect all changes in complex samples, targeted sequencing, which consists in the isolation and sequencing of a specific region of the genome, has begun to develop. …”
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19463
From the guest editors
Published 2013-07-01“…His research program is at the interface of the mathematical and natural and social sciences with emphasis on (i) the role of dynamic social landscapes on disease dispersal; (ii) the role of environmental and social structures on the dynamics of addiction and disease evolution, and (iii) Dynamics of complex systems at the interphase of ecology, epidemiology and the social sciences. …”
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19464
Simulation of Payne Effect of Elastomeric Isolators with a Harmonic Balance Method
Published 2012-01-01“…This methodology has the advantage of using tabular experimental data from characterization tests which avoids the development of a complex model. In order to compute frequency responses, the non linear harmonic balance method is used and, for each iteration, new rubber properties are affected at each element according to its strain state. …”
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19465
About a concept of creating a social network users information aggregation and data processing system
Published 2019-02-01“…The developed universal system is based on the information technology of data warehousing, and it has the following aspects: an expandable complex subject area, the integration of stored data that come from various sources, the invariance of stored data in time with mandatory labels, relatively high data stability, the search for necessary trade-off in data redundancy, modularity of individual system units, fl and extensibility of the architecture, high security requirements vulnerable data.The proposed system organizes the process of collecting data and filling the database from external sources. …”
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19466
CRISPR-Based Programmable Nucleic Acid-Binding Protein Technology Can Specifically Detect Fatal Tropical Disease-Causing Pathogens
Published 2022-01-01“…Furthermore, the discovery of programmable trans-cleavage Cas proteins like Cas12a and Cas13 that can collaterally damage reporter-containing single-stranded DNA or RNA upon formation of target Cas-gRNA complex has strengthened this technology with enhanced sensitivity. …”
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19467
Development and evaluation of winter barley varieties for group resistance to smut diseases
Published 2015-07-01“…The first varieties bred by PBGI – NCSCI (Ukraine) that possessed complex disease resistance to smut diseases were Zimovyi (2005), Dostoinyi, Trudivnyk, Selena Star, and Aborihen (2006). …”
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19468
Exploring RNA-Seq Data Analysis Through Visualization Techniques and Tools: A Systematic Review of Opportunities and Limitations for Clinical Applications
Published 2025-01-01“…With the increasing availability of RNA-seq data analysis from clinical studies and patient samples, the development of effective visualization tools for RNA-seq analysis has become increasingly important to help clinicians and biomedical researchers better understand the complex patterns of gene expression associated with health and disease. …”
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19469
An Exploratory Investigation of Chatbot Applications in Anxiety Management: A Focus on Personalized Interventions
Published 2024-12-01“…However, limitations persist, such as the lack of human empathy, ethical and privacy concerns related to data security, and technical challenges in understanding complex human emotions. The key challenges identified involve enhancing the emotional intelligence of chatbots, integrating them with traditional therapy, and establishing robust ethical frameworks to ensure user safety and data protection. …”
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19470
Contributions of a Child's Built, Natural, and Social Environments to Their General Cognitive Ability: A Systematic Scoping Review.
Published 2016-01-01“…The etiology of a child's cognitive ability is complex, with research suggesting that it is not attributed to a single determinant or even a defined period of exposure. …”
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19471
Symbiotic Root-Endophytic Soil Microbes Improve Crop Productivity and Provide Environmental Benefits
Published 2019-01-01“…Plants should not be regarded as entities unto themselves, but as the visible part of plant-microbe complexes which are best understood as “holobiomes.” …”
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19472
4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets
Published 2025-01-01“…At the moment, there are neither approved vaccines nor effective drugs for the treatment of human leishmaniasis for any of its three typical clinical manifestations, and, importantly, the drugs of clinical use have several side effects, require complex administration regimens, present high cost, and are ineffective in many populations due to pathogen resistance. …”
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19473
Gestion, évaluation et stabilisation de cuirs archéologiques provenant de la fouille du boulevard Dr Henri-Henrot à Reims/Durocortorum
Published 2022-11-01“…The well-structured supervision and treatment of this material culture, whose manipulation was particularly complex due to its fragile nature, nonetheless allowed for its successful conservation and complete study.…”
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19474
Interdisciplinary Approaches in Doctoral and Higher Research Education: An Integrative Scoping Review
Published 2025-01-01“…Interdisciplinary approaches are increasingly integral in doctoral and higher research education, addressing complex global challenges through collaborations across disciplines. …”
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19475
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19476
Numerical Study of Leakage and Rotordynamic Performance of Staggered Labyrinth Seals Working with Supercritical Carbon Dioxide
Published 2022-01-01“…When the rotor with convex plate operates without axial shifting, the cross-coupled complex dynamic stiffness (hR) of the staggered labyrinth seal shows little effect on the Ceff, and the average direct damping (Cavg) has a dominant influence on the Ceff. …”
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19477
Allelic diversity of the <i>FaOMT</i> gene (mesifurane biosynthesis) in promising strawberry cultivars and selected forms developed at the I.V. Michurin Federal Science Center
Published 2022-06-01“…Identification of genotypes carrying the genes of the aromatic complex in fruits is an important stage in the development of new cultivars with aromatic fruits. …”
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19479
The effect of income and smallholder characteristics on cultivation, harvesting, and post-harvest management of natural rubber
Published 2023-10-01“…Partial least square path modeling was used with SmartPLS software to estimate the complex cause-effect relationships of smallholder and farm factors for adopting sustainable agricultural practices.FINDINGS: The effect of the relationship between income and smallholder characteristics on cultivation and income on post-harvest management was not significant. …”
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19480
Coherence Resonance Behavior of FitzHugh-Nagumo Neurons Induced by Electromagnetic Field Driven by Phase Noise
Published 2022-01-01“…Noise can not only enhance but also weaken the ability of the nervous system to process information. Neurons are in a complex and variable electromagnetic field. Electromagnetic induction plays an important role in regulating the changes of neuronal membrane potential. …”
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