A Review on the Role of Human Solute Carriers Transporters in Cancer by Md. Shafiul Hossen, Mohammed Shafin Ul Islam, Mohammad Yasin, Mohammed Ibrahim, Abhijit Das

“…As solute carriers (SLC) transporters are capable of transporting different amino acids, cancer may develop as a result of these transporters' over‐expression due to their complex formation with other biological molecules. …”
Get full text

From data on gross activity to the characterization of animal behaviour: which metrics for which purposes? by van Dixhoorn, Ingrid, Aubé, Lydiane, van Zyl, Coenraad, de Mol, Rudi, van der Werf, Joop, Lardy, Romain, Mialon, Marie-Madeleine, van Reenen, Kees, Veissier, Isabelle

“…Various metrics can be calculated from activity data. Complex patterns of activity within or between individuals, such as cyclic patterns and synchrony, can inform on the biological functioning, the health status, or the welfare of an animal. …”
Get full text

Behavior and Mechanisms of Antimony Precipitation from Wastewater by Sulfate-Reducing Bacteria <i>Desulfovibrio desulfuricans</i> by Fan Zhuang, Xiaowu Xiang, Jin Hu, Jing Xiong, Teng Zhang, Lei Zhou, Guoping Jiang, Min Zhang, Zhenghua Liu, Huaqun Yin, Ling Xia, Ibrahim Ahmed Ibrahim Mahmoud, Delong Meng

“…The precipitation of heavy metals by microorganisms involves complex mechanisms that require further investigation to optimize bioremediation technologies. …”
Get full text

FS-DDPG: Optimal Control of a Fan Coil Unit System Based on Safe Reinforcement Learning by Chenyang Li, Qiming Fu, Jianping Chen, You Lu, Yunzhe Wang, Hongjie Wu

“…In the future, we will further improve the scalability and apply the method to more complex FCU systems in variable environments.…”
Get full text

The Cog-4 Subset of the National Institutes of Health Stroke Scale as a Measure of Cognition: Relationship with Baseline Factors and Functional Outcome after Stroke Using Data from... by Sandeep Ankolekar, Cheryl Renton, Nikola Sprigg, Philip M. W. Bath

“…Assessing poststroke cognitive impairment is complex. A subscale of the NIHSS, the Cog-4, has been proposed as a quick test of “cognitive impairment.” but a study of its properties in a larger dataset is lacking. …”
Get full text

Regional gray matter thickness correlations of the hearing and deaf feline brains by Stephen G. Gordon, Alessandra Sacco, Stephen G. Lomber

“…In corroboration with previous feline structural- and diffusion-based neuroimaging literature, these results imply a reorganization of cortical gray matter to increase the overall processing of the remaining senses within a potentially less complex and more redundant connectome. The present study adds to the developing field of deafness literature through the implementation of novel analyses that add an additional perspective on neuroplasticity within the feline brain.…”
Get full text

Ultrastructural Characteristics of Rat Hepatic Oval Cells and Their Intercellular Contacts in the Model of Biliary Fibrosis: New Insights into Experimental Liver Fibrogenesis by Joanna Maria Lotowska, Maria Elzbieta Sobaniec-Lotowska, Dariusz Marek Lebensztejn, Urszula Daniluk, Piotr Sobaniec, Krzysztof Sendrowski, Jaroslaw Daniluk, Joanna Reszec, Wojciech Debek

“…Better understanding of the complex cellular interactions between HPCs and adjacent NPCs, especially T-HSCs, may help develop antifibrotic therapies in the future.…”
Get full text

Reprogramming of iPSCs to NPCEC-like cells by biomimetic scaffolds for zonular fiber reconstruction by Tianhui Chen, Zhongxing Chen, Juan Du, Min Zhang, Zexu Chen, Qingyi Gao, Aodong Chen, Qinghao Meng, Yang Sun, Yan liu, Linghao Song, Xinyue Wang, Pranav Prakash Edavi, Chen Xu, Hongmei Zhang, Jinhai Huang, Yongxiang Jiang

“…Ectopia lentis (EL), characterised by impaired zonular fibers originating from non-pigmented ciliary epithelial cells (NPCEC), presents formidable surgical complexities and potential risks of visual impairment. …”
Get full text

Scale effects of physically based TOPKAPI model in reservoir inflow flood forecasting for ungauged basins by Yihua Sheng, Zhijia Li, Zhiyu Liu, Yalei Han, Jie Wang, Junfu Gong, Ning Xu

“…Study focus: After the construction and water storage of the reservoir, the conditions for runoff generation and routing method near the dam site have changed significantly. Certain complex, scale-related issues remain insufficiently understood, limiting the application of physically based distributed hydrological models in this area. …”
Get full text

Differentiated effects and mechanisms of N-, P-, S-, and Fe-modified biochar materials for remediating Cd- and Pb-contaminated calcareous soil by Amir Bostani, Xingying Meng, Le Jiao, Srđan D. Rončević, Peng Zhang, Hongwen Sun

“…NBC, PBC, and SBC effectively immobilized Cd and Pb in the soil and significantly reduced their accumulation in Chinese cabbage by 34.4 %-58.9 % for Cd and 9.2 %-53.1 % for Pb, with PBC having the best effect, attributed to complexation, precipitation, and adsorption. However, FBC had strong acidity and poor immobilization ability, which increased the available concentrations of Cd and Pb in the soil. …”
Get full text

Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation by Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu

“…Molecular docking analysis revealed that nicotine and nicotyrine bind to and promote the autophagic-dependent degradation of MMS19, a key component of the CIA complex. MMS19 KD led to the autophagic degradation of several ISC proteins involved in DNA damage repair and mitochondrial respiratory function, thereby inhibiting cell proliferation. …”
Get full text

Zero-TCE: Zero Reference Tri-Curve Enhancement for Low-Light Images by Chengkang Yu, Guangliang Han, Mengyang Pan, Xiaotian Wu, Anping Deng

“…We compare our proposed method against ten other advanced algorithms based on multiple datasets, including LOL, DICM, MEF, NPE, and ExDark, that encompass complex illumination variations. Experimental results demonstrate that the proposed algorithm adapts better to the characteristics of images captured in low-light environments, producing enhanced images with sharp contrast, rich details, and preserved color authenticity, while effectively mitigating the issue of overexposure.…”
Get full text

Fusion of multi-scale attention for aerial images small-target detection model based on PARE-YOLO by Huiying Zhang, Pan Xiao, Feifan Yao, Qinghua Zhang, Yifei Gong

“…Abstract In view of the complex environments and varying object scales in drone-captured imagery, a novel PARE-YOLO algorithm based on YOLOv8 for small object detection is proposed. …”
Get full text

A Semi-Automated Usability Evaluation Framework for Interactive Image Segmentation Systems by Mario Amrehn, Stefan Steidl, Reinier Kortekaas, Maddalena Strumia, Markus Weingarten, Markus Kowarschik, Andreas Maier

“…For complex segmentation tasks, the achievable accuracy of fully automated systems is inherently limited. …”
Get full text

Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics by You Hu, Jun Xu, Jian Lv, Yan Qin, Yongda Lu, Fan Cen, Hongbao Yang, Kai Chen, Suhua Xia

“…Gastric cancer is characterized by high heterogeneity, with its complex microenvironment and intercellular communications playing critical roles in disease progression and treatment responses. …”
Get full text

Interaction of Musicianship and Aging: A Comparison of Cortical Auditory Evoked Potentials by Jennifer L. O’Brien, Dee A. Nikjeh, Jennifer J. Lister

“…Cortical auditory evoked potentials (CAEPs) elicited by harmonic tone complexes were examined, including P1-N1-P2, mismatch negativity (MMN), and P3a. …”
Get full text

Effect of opercular deformity on morphological and transcriptomic profiling of gills in golden pompano (Trachinotus ovatus) by Yuwei Wu, Qian Ma, Dihao Huang, Liuyong Wang, Qiling Zhou, Chunli Ran, Gang Chen

“…Skeletal deformities in the opercular complex, jaws, and vertebral column are the most common consequences. …”
Get full text

Reactive Oxygen Species Generation in Human Cells by a Novel Magnetic Resonance Imaging Contrast Agent by Li Wang, Eric Lin, Mary J. Johansen, Timothy Madden, Edward Felix, Karen S. Martirosyan, Steven J. Frank

“…The novel positive-contrast magnetic resonance imaging (MRI) marker C4 consists of an aqueous solution of cobalt chloride (CoCl2) complexed with the chelator N-acetylcysteine (NAC). …”
Get full text

Plant Leaf Identification Using Feature Fusion of Wavelet Scattering Network and CNN With PCA Classifier by S. Gowthaman, Abhishek Das

“…Conversely, MobileNetV2 deep layer features complement this by capturing more complex, high-level features like shapes and edges, which are essential for distinguishing between different plant species. …”
Get full text

Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia by David Olivares-Berjaga, Albert Martínez-Pinteño, Natalia Rodríguez, Sergi Mas, Constanza Morén, Eduard Parellada, Patricia Gassó

“…Abstract Schizophrenia (SZ) is a deleterious brain disorder characterised by its heterogeneity and complex symptomatology consisting of positive, negative and cognitive deficits. …”
Get full text