Dissecting the Molecular Mechanism of Wang-Bi Capsule in the Treatment of Experimental Rheumatoid Arthritis Based on Synovial Tissue Proteomic Analysis by Haiyang Shu, Yingjie Shi, Li Li, Ning Zhao, Cheng Lu, Aiping Lu, Xiaojuan He

“…The expression levels of proteins including matrix metalloproteinase 3 (MMP3), MMP19, lipopolysaccharide-binding protein (LBP), serine/threonine kinase interleukin-1 receptor-associated kinase 4 (IRAK4), and actin-related protein 2/3 complex subunit 5 (ARPC5) in these pathways were downregulated significantly by WB when compared with the model group. …”
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Economic Evaluations of Health Service Interventions Targeting Patients with Multimorbidities: A Scoping Literature Review by Lucia Ferrara, Vittoria Ardito, Valeria D. Tozzi, Rosanna Tarricone

“…Despite the heightened interest toward integrated care programs as a response to the complex need of multimorbid patients, economic evaluations of these programs remain scarce. …”
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Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report by Aya Kawasaki, MD, Hidefumi Tonoki, MD, PhD, Osamu Sasaki, MD, PhD, Yoko Matsushita, MD, PhD, Michiko Watari, MD, PhD, Nobuhiro Takahashi, MD, Satoko Fujieda, MD

“…This pathogenic variant is located on exon 10 of the TSC2 gene, which encodes the hamartin binding domain, leading to impair inhibitory function of the hamartin-tuberin complex, which activates mammalian target of rapamycin(mTOR) activity. …”
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Synthesis, antimicrobial evaluation, ADMET prediction, molecular docking and dynamics studies of pyridine and thiophene moiety-containing chalcones by Fahmida Akhter, Sumita Saznin Marufa, S. M. Anyet Ullah Shohag, Hiroshi Nishino, Mohammad Sayed Alam, Md. Aminul Haque, Mohammad Mostafizur Rahman

“…Molecular dynamics simulation was scrutinized further for compound 1c in three protein–ligand complexes where root mean square deviation and root mean square fluctuation data were below 2 Å, proposing its stability inside and minimal structural changes.…”
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African swine fever in the Republic of Crimea in 2015–2018 by N. G. Kosharny, S. I. Danylchenko, M. A. Pasunkina, D. V. Gadzevich, N. G. Vorotilova

“…It should be noted that in case of ASF occurrence in domestic pigs only, the disease could be eradicated with a complex of anti-epizootic measures in initial outbreak areas. …”
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How Can Law and Policy Reform Shape Human Resource Strategies in Indonesian State Universities Post-Law No. 20 of 2023? by Siti Mursidah, Cahya Wulandari, Moh Khoiruddin, Muhammad Sayuti Hassan, Ricky Dermawan Fauzi

“…The study reveals that while some universities have begun to adopt the provisions of the law, they still face significant challenges, including a lack of professional training and development, complex bureaucratic processes, and budget constraints. …”
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Simultaneous analysis of cytokines and co-stimulatory molecules concentrations by ELISA technique andof probabilities of measurable concentrations of interleukins IL-2, IL-4, IL-5,... by Klabusay Martin, Kohutova Viera, Coupek Petr, Nenickova Marie, Tesarova Eva

“…The cytokine network remarkably influences homeostasis. There is not a complex analysis describing physiological values of soluble cytokines in healthy individuals. …”
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A Novel Hybrid Model for Credit Risk Assessment of Supply Chain Finance Based on Topological Data Analysis and Graph Neural Network by Kosar Farajpour Mojdehi, Babak Amiri, Amirali Haddadi

“…Supply Chain Finance (SCF) in the energy sector has emerged as a critical area of focus due to the need for sustainable and efficient financial solutions to manage the complex interactions between various stakeholders, including suppliers, financial institutions, and energy companies. …”
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SOCIAL ENTREPRENEURIAL VENTURES IN VIETNAM: AN IDEOGRAPHIC LENS by Yolanda Sarason, Kristi Yuthas, Linh Nguyen

“…Trang contemplated how much easier it had been to develop Fargreen’s business model on paper than to implement it within the complex realities of Vietnam’s intricate social ties, evolving political and economic systems, difficult infrastructure, and unique history and culture. …”
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Differences in category information processing between areas TEO and TE of the macaque by Masaumi Shimizu, Shun Katakami, Masato Okada, Yasuko Sugase-Miyamoto, Kazuko Hayashi, Kazuko Hayashi, Keiji Matsuda, Kenichiro Miura, Kenichiro Miura, Mark A. G. Eldridge, Richard C. Saunders, Barry J. Richmond, Narihisa Matsumoto

“…Neurons that respond to a class of complex objects, such as faces, can be found in inferior temporal cortex of macaque monkeys, comprising areas TEO and TE. …”
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Enhancing Thermal-Hydraulic Modelling in Dual Fluid Reactor Demonstrator: The Impact of Variable Turbulent Prandtl Number by Hisham Elgendy, Sławomir Kubacki, Konrad Czerski

“…Future work will apply this modelling approach to more complex geometries and flow scenarios to optimise thermal-hydraulic performance.…”
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The landscape of cell regulatory and communication networks in the human dental follicle by Jia-Ning Liu, Jia-Ning Liu, Jiong-Yi Tian, Lu Liu, Lu Liu, Yuan Cao, Yuan Cao, Xiao Lei, Xiao Lei, Xiao-Hui Zhang, Xiao-Hui Zhang, Zi-Qi Zhang, Zi-Qi Zhang, Jun-Xi He, Jun-Xi He, Chen-Xi Zheng, Chao Ma, Sheng-Feng Bai, Bing-Dong Sui, Fang Jin, Ji Chen, Ji Chen

“…Cell–cell communication analysis unraveled crosstalk between vascular and immune cell components in orchestrating dental follicle biological activities, potentially based on COLLAGAN-CD44 ligand–receptor pairs, as well as ANGPTL1-ITGA/ITGB ligand–receptor pairs.ConclusionWe establish a landscape of cell regulatory and communication networks in the human dental follicle, providing mechanistic insights into the cellular regulation and interactions in the complex dental follicle tissue microenvironment.…”
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Synthesis of a Novel Ce-bpdc for the Effective Removal of Fluoride from Aqueous Solution by Changqing Zhao, Yanwei Cui, Fang Fang, Si Ok Ryu, Jiarui Huang

“…The Ce-bpdc coordination complex exhibited high binding capacity for fluoride ions. …”
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Restoration of Genetic Code in Macular Mouse Fibroblasts via APOBEC1-Mediated RNA Editing by Sonali Bhakta, Hiroko Kodama, Masakazu Mimaki, Toshifumi Tsukahara

“…Identification of the core component of the apoB RNA editing holoenzyme, APOBEC, and investigation into new candidate genes encoding other elements of the complex could reveal further details regarding APOBEC-mediated mRNA editing. …”
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Explicit Form of Exact Analytical Solution for Calculating Ground Displacement and Stress Induced by Shallow Tunneling and Its Application by Caixia Guo, Kaihang Han, Heng Kong, Leilei Shi

“…To obtain the ground displacements and stresses induced by shallow tunneling and existing pile foundation loads, the key procedure involves superimposing the analytical solution for shallow tunneling in green-field with the analytical solution for existing structure loads. In green-field, the complex variable method provides exact analytical solutions of ground displacements and stresses caused by shallow tunneling. …”
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A novel approach to Lyapunov stability of Caputo fractional dynamic equations on time scale using a new generalized derivative by Michael Precious Ineh, Edet Peter Akpan, Hossam A. Nabwey

“…The inclusion of fractional orders enabled the modeling of more complex dynamics that occur in real-world systems, particularly those involving both continuous and discrete time components. …”
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Neighbourhood, crime and fear: Exploring subjective perception of security in Serbia by Marković Aleksandra, Filipović Božidar

“…By examining determinants such as age, gender, daily activity, area (rural or urban), social capital, interpersonal trust and perceived quality of society, this paper aims to shed light on the complexities of security perception. The primary findings underscore the significance of individual vulnerability and social integration measures as critical indicators of security perceptions in the neighbourhoods. …”
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The Ultrasonic P-Wave Velocity-Stress Relationship and Energy Evolution of Sandstone under Uniaxial Loading-Unloading Conditions by Long Zhang, Zetian Zhang, Ru Zhang, Mingzhong Gao, Jing Xie

“…During mining, a deep rock mass experiences complex mining-induced stress evolution, damage accumulation, and deformation failure processes, and the mechanical and acoustic properties of the rock constantly change. …”
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Transformation of University Models: Analysis of the Development Strategies of Universities in the World by D. A. Shtykhno, L. V. Konstantinova, N. N. Gagiev, E. A. Smirnova, O. D. Nikonova

“…The defining parameters for the formation of the model of the university of the future are focus on innovation and advanced continuous education, managed broad integration, diversification of income sources, social involvement and contribution to sustainable development. The presented complex of the main characteristics of typological models of universities can serve as a tool for assessing the compliance of a particular university with a particular model, as well as contribute to goal-setting in the development of the national higher education system and particular universities.…”
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Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation by Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia

“…Molecular dynamics simulations have also been carried out to check stability of binding complex in water for 1000 ps. Our molecular docking and simulation have predicted high binding affinity of secondary metabolite (C28H34N2O6) to AChE. …”
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