Beyond immortality: Epstein–Barr virus and the intricate dance of programmed cell death in cancer development by Arezoo Esmaeili, Prankur Awasthi, Samira Tabaee

“…This review underscores the critical necessity for ongoing investigation into the complex interplay between EBV and host cell death mechanisms, with the ultimate goal of enhancing patient outcomes in EBV-associated diseases.…”
Get full text

Preliminary Study on the Impact of Ruminal Ciliate Inoculation in Fauna-Free Conditions on the Ruminal Fermentation and Ciliate–Prokaryote Association In Vitro by Geonwoo Kim, Woohyung Lee, Tansol Park

“…Ruminants rely on the rumen for the anaerobic fermentation of fibrous plant materials, facilitated by a complex microbial community of bacteria, archaea, fungi, and ciliates. …”
Get full text

GENES DETERMINING THE SYNTHESIS OF LAVONOID AND MELANIN PIGMENTS IN BARLEY by O. Yu. Shoeva, K. V. Strygina, E. K. Khlestkina

“…Melanins are less studied pigments of plants. Due to the complex structure and resistance to various solvents, the chemical nature of these pigments has not been established. …”
Get full text

THE DIFFERENCE BETWEEN THE CONCEPT OF JUSTICE IN THE CONSTITUTION OF AFGHANISTAN AND THE REPUBLIC OF KAZAKHSTAN by Х. Мохаммади, С.Б. Бейсебаева, А.С. Сабыр, Б.Е. Тлеулов, Г.Т. Муратова

“…This brief comparison underscores the complexities inherent in conceptualizing and realizing justice within constitutional frameworks. …”
Get full text

Effects of Nanoscale Carbon Black Modified by HNO3 on Immobilization and Phytoavailability of Ni in Contaminated Soil by Jiemin Cheng, Lei Yu, Tong Li, Yuzhen Liu, Chengxiu Lu, Tingting Li, Hanwei Wang

“…Results indicated that MCB had much lower negative zeta potential, more functional groups for exchange and complexation of cation, and more heterogeneous pores and cavities for the adsorption of cation than the unmodified parent one (CB). …”
Get full text

GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand by Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki

“…GFRα1 bound to a receptor complex consisting of NCAM and integrin α7β1 of dorsal root ganglion neurons in a GDNF‐RET independent manner. …”
Get full text

The Kat in the HAT: The Histone Acetyl Transferase Kat6b (MYST4) Is Downregulated in Murine Macrophages in Response to LPS by Smita Shukla, Carly Levine, Roopa Payanur Sripathi, Genie Elson, Carol Susan Lutz, Samuel Joseph Leibovich

“…In this study, we show that the histone acetyl transferase (HAT) Kat6B (MYST4) is strongly suppressed (>80%) in macrophages by lipopolysaccharide (LPS) (M1 activation), while Kat6A, its partner in the MOZ/MORF complex, is reciprocally upregulated. This pattern of expression is not altered by LPS together with the adenosine receptor agonist NECA (M2d activation). …”
Get full text

Impact of a Segmented-Scan Strategy on Residual Stress and Fit Accuracy of Dental Prostheses Fabricated via Laser-Beam Powder-Bed Fusion by Yoshio Kobayashi, Atsushi Takaichi, Yuka Kajima, Wenrui Qu, Noriyuki Wakabayashi

“…The laser-beam powder-bed fusion (PBF-LB) method enables the semi-automatic fabrication of complex three-dimensional structures, making it useful for dental prostheses. …”
Get full text

Implementing digital respiratory technologies for people with respiratory conditions: A protocol for a scoping review. by Chi Yan Hui, Kathleena Condon, Shailesh Kolekar, Nicola Roberts, Katherina Bernadette Sreter, Sami O Simons, Carlos Figueiredo, Zoe McKeough, Hani Salim, Aleksandra Gawlik-Lipinski, Apolline Gonsard, Ayşe Önal Aral, Anna Vanoverschelde, Matthew Armstrong, Dario Kohlbrenner, Cátia Paixão, Patrick Stafler, Efthymia Papadopoulou, Adrian Paul Rabe, Milan Mohammad, Izolde Bouloukaki, Shirley Quach, Malek Chaabouni, Georgios Kaltsakas, Kate Loveys, Tonje Reier-Nilsen, Anthony Paulo Sunjaya, Paul Robinson, Hilary Pinnock, Amy Hai Yan Chan

“…The value of 'data-enabled', digital healthcare is evolving rapidly, as demonstrated in the COVID-19 pandemic, and its successful implementation remains complex and challenging. Harmonisation (within/between healthcare systems) of infrastructure and implementation strategies has the potential to promote safe, equitable and accessible digital healthcare, but guidance for implementation is lacking. …”
Get full text

Oilpalm-RTMDet: An lightweight oil palm detector base on RTMDet by Jirong Ding, Runlian Huang, Yehua Liang, Xin Weng, Jianjun Chen, Haotian You

“…Moreover, Oilpalm-RTMDET model can realize accurate and rapid detection of oil palm trees under complex conditions such as overlapping canopy, different tree structures and varying canopy sizes. …”
Get full text

Schisandrin B Attenuates Airway Inflammation by Regulating the NF-κB/Nrf2 Signaling Pathway in Mouse Models of Asthma by Yaqin Chen, Yu Kong, Qili Wang, Jian Chen, Hua Chen, Huihui Xie, Lan Li

“…Background. Asthma is a complex inflammatory disorder that plagues a large number of people. …”
Get full text

MESH CONVERGENCE TEST BY USING FINITE ELEMENT ANALYSIS (FEA) IN SHAFT LOADING OF 2 KW INDUCTION MOTOR by Lambert Hotma, Nur Cholis Majid, Marsalyna, Jekki Hendrawan, Nirma Afrisanti Kinasih, Dwi Jaya Febriansyah, Bayu Novariawan, Muhammad Reza Alfin, Intan Satwika Putri, Muhammad Thowil Afif, Budi Noviyantoro Fadjrin, Endra Dwi Purnomo

“…Finite Element Analysis (FEA) is a calculation tool to find out a determined solution for a complex structure subjected to some certain static load. …”
Get full text

Land use/cover change simulation research: A system literature review based on bibliometric analyses by Meili Chen, Narimah Samat, Mohammad Javad Maghsoodi Tilaki, Liyuan Duan

“…Enhancing the coupling of models improves understanding and prediction of complex LUCC processes, supporting global environmental research, resource management, and policymaking. …”
Get full text

Possible Roles of IL-33 in the Innate-Adaptive Immune Crosstalk of Psoriasis Pathogenesis by Serafinella Patrizia Cannavò, Lucrezia Bertino, Eleonora Di Salvo, Valeria Papaianni, Elvira Ventura-Spagnolo, Sebastiano Gangemi

“…The core of the future research on psoriasis could be to fully understand the role of this complex cytokine, in order also to find a new therapeutic approach.…”
Get full text

Effect of plasma beta on the nonlinear evolution of m/n = 2/1 double tearing mode in high Lundquist number regime by Dingzong Zhang, Zhaoqing Wu, Jun Ma, Wenfeng Guo, Yanqing Huang, Hongbo Liu

“…However, when the separation is relatively large ( $\Delta r = 0.2$ or $\Delta r = 0.3$ ), plasmoids exhibit highly complex behavior under different plasma beta and resistivity conditions. …”
Get full text

Atypical Radiographic Presentation of Cryptococcus Pneumonia in a Newly Diagnosed HIV Patient by Arthur Cacacho, Umair Ashraf, Arsalan Rehmani, Masooma Niazi, Misbahuddin Khaja

“…Interferon-gamma release assay, Mycobacterium tuberculosis PCR, and acid-fast bacilli staining of the bronchoalveolar lavage were negative for the M. tuberculosis complex. Conclusion. The similarities in clinical and imaging findings among patients with acute immunodeficiency syndrome with coinfections make diagnoses difficult; thus image-guided biopsies are essential to confirm diagnoses.…”
Get full text

Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review by Deenadhayalan Ashok, Monisha Prasad, Mohammad Fareed, Anis Ahmad Chaudhary

“…Environmental factors that impact the development and course of the disease, including nutrition, exercise and pollution exposure, also have an impact on these epigenetic modifications. Knowing the complex interactions among genetics, epigenetics and environment is essential to pinpointing the precise aetiology of T2DM and creating customised treatment regimens. …”
Get full text

Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches by Domenico Lombardo, Mikhail A. Kiselev, Salvatore Magazù, Pietro Calandra

“…While amphiphiles self-assembly has attracted considerable attention for decades due to their extensive applications in material science, drug and gene delivery, recent developments in nanoscience stimulated the combination of the simple approaches of amphiphile assembly with the advanced concept of supramolecular self-assembly for the development of more complex, hierarchical nanostructures. Introduction of stimulus responsive supramolecular amphiphile assembly-disassembly processes provides particularly novel approaches for impacting bionanotechnology applications. …”
Get full text

Exploring the Pharmacological Potential of Carrageenan Disaccharides as Antitumor Agents: An In Silico Approach by Ohana Leticia Tavares Silva, Monique Gabriela das Chagas Faustino Alves, Hugo Alexandre Oliveira Rocha

“…Notably, six of the complexes formed exhibited interactions between the disaccharides and the zinc cofactor, which represents a primary mechanism of inhibition for these targets. …”
Get full text

Data-knowledge hybrid driven intelligent prediction method of tunnel excavation profiles geometric deformation by Ya Hu, Jingyi Lu, Jun Zhu, Huixin Zhang, Ying Ren, Jianlin Wu, Jianbo Lai, Heng Zhang, Hongyue Zhao, Xiang Zeng

“…Applying digital twin technology to the tunnel excavation process enables intelligent tunnel construction, which is critical for ensuring construction safety and advancing intelligent building methods. However, the complex construction environment, involving numerous environmental factors and dynamic changes, poses challenges for traditional deformation prediction and analysis methods. …”
Get full text