Association between METTL14 gene polymorphisms and risk of ovarian endometriosis by Zijun Zhou, Zijun Zhou, Youkun Jie, Xianyue Hu, Xianyue Hu, Guange Chen, Yanjing Bao, Yanjing Bao, Zhenbo OuYang, Liangzhi Wu, Tianyang Gao, Qiushi Zhang, Qiushi Zhang, Wenfeng Hua, Wenfeng Hua

“…Methyltransferase-like 14 (METTL14), a crucial component of the N6-methyladenosine (m6A) RNA methyltransferase complex and an RNA binding scaffold, is known to play a pivotal role in various human diseases. …”
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Long-term trends and patterns in ultra-processed food consumption among Korean adults from 1998 to 2022 by Hyeseung Lee, Yesol Yim, Yerin Cho, Jiyeon Oh, Soeun Kim, Yejun Son, Hyesu Jo, Seohyun Hong, Masoud Rahmati, Hanseul Cho, Jiyoung Hwang, Dong Keon Yon

“…Sampling weights were applied to adjust for the complex survey design and non-responses. We calculated the weighted means and confidence intervals for the proportion of energy intake by NOVA food groups and various nutrient profiles. …”
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Implications of water management on methane emissions and grain yield in paddy rice: A case study under subtropical conditions in Brazil using the CSM-CERES-Rice model by Evandro H. Figueiredo Moura da Silva, Gerrit Hoogenboom, Kenneth J. Boote, Santiago Vianna Cuadra, Cheryl H. Porter, Walkyria Bueno Scivittaro, Silvio Steinmetz, Carlos E. Pellegrino Cerri

“…In this context, process-based crop models are useful tools for understanding and predicting the complex interactions between crop production, environmental factors, and sustainability. …”
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Behavioural components and delivery features of early childhood obesity prevention interventions: intervention coding of studies in the TOPCHILD Collaboration systematic review by Brittany J. Johnson, Paul M. Chadwick, Samantha Pryde, Anna Lene Seidler, Kylie E. Hunter, Mason Aberoumand, Jonathan G. Williams, Hei In Lau, Sol Libesman, Jannik Aagerup, Angie Barba, Louise A. Baur, Samantha Morgillo, Lee Sanders, Sarah Taki, Kylie D. Hesketh, Karen Campbell, Alexandra Manson, Alison Hayes, Angela Webster, Charles Wood, Denise A. O’Connor, Karen Matvienko-Sikar, Kristy Robledo, Lisa Askie, Luke Wolfenden, Rachael Taylor, H. Shonna Yin, Vicki Brown, Alexander Fiks, Alison Ventura, Ata Ghaderi, Barry J. Taylor, Cathleen Stough, Christine Helle, Cristina Palacios, Eliana M. Perrin, Elizabeth Reifsnider, Finn Rasmussen, Ian M. Paul, Jennifer S. Savage, Jessica Thomson, Jinan Banna, Junilla Larsen, Kaumudi Joshipura, Ken K. Ong, Levie Karssen, Li Ming Wen, Márcia Vitolo, Margrethe Røed, Maria Bryant, Maribel Campos Rivera, Mary Jo Messito, Natalia Golova, Nina Cecilie Øverby, Rachel Gross, Rajalakshmi Lakshman, Rebecca Byrne, Russell L. Rothman, Sharleen O’Reilly, Stephanie Anzman-Frasca, Vera Verbestel, Claudio Maffeis, Kayla de la Haye, Sarah-Jeanne Salvy, Seema Mihrshahi, Janani Ramachandran, Paola Seffrin Baratto, Rebecca K. Golley, on behalf of the TOPCHILD Collaboration

“…Conclusions Our study provides the most comprehensive description of the behaviour change content of complex interventions targeting early childhood obesity prevention available to date. …”
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A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Despite its accessibility and wider coverage of public health insurance, the integrated service model in Indonesia faces challenges associated with complex regulations and the availability of medication. …”
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Conclusions: HCPs identified facilitators and barriers which highlight the complexities associated with BPG as secondary prophylaxis for RHD in Ethiopia. …”
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Effect of colloidal particle size on physicochemical properties and aggregation behaviors of two alkaline soils by Y. Yan, X. Zhang, C. Xu, C. Xu, J. Liu, F. Hu, F. Hu, Z. Geng, Z. Geng

“…These findings can provide references for in-depth understanding of the environmental behaviors of the heterogeneous soil organic–mineral complexes.</p>…”
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An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape by Weiqi Deng, Weiqi Deng, Xuefeng Niu, Ping He, Ping He, Qihong Yan, Qihong Yan, Huan Liang, Yongping Wang, Yongping Wang, Lishan Ning, Lishan Ning, Zihan Lin, Zihan Lin, Yudi Zhang, Xinwei Zhao, Xinwei Zhao, Liqiang Feng, Linbing Qu, Ling Chen, Ling Chen

“…Primary docking was performed using ZDOCK (3.0.2) to generate the initial conformation of the antigen-antibody complex, followed by simulations of the complete conformations using Rosetta SnugDock software. …”
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Exploring the association between tissue sodium content, heart failure subtypes, and symptom burden: insights from magnetic resonance imaging by Djawid Hashemi, Djawid Hashemi, Djawid Hashemi, Djawid Hashemi, Karl Jakob Weiß, Karl Jakob Weiß, Karl Jakob Weiß, Patrick Doeblin, Patrick Doeblin, Patrick Doeblin, Moritz Blum, Radu Tanacli, Radu Tanacli, Radu Tanacli, Hana Camdzic, Hana Camdzic, Hans-Dirk Düngen, Hans-Dirk Düngen, Frank Edelmann, Frank Edelmann, Frank Edelmann, Titus Kuehne, Titus Kuehne, Titus Kuehne, Marcus Kelm, Marcus Kelm, Marcus Kelm, Sebastian Kelle, Sebastian Kelle, Sebastian Kelle

“…AimsHeart failure (HF) is a complex clinical syndrome with high morbidity and mortality, influenced significantly by sodium balance. …”
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The protein composition of human adenovirus replication compartments by Paloma Hidalgo, Amada Torres, Pierre M. Jean Beltran, Gamaliel López-Leal, Luca D. Bertzbach, Thomas Dobner, S. J. Flint, Ileana M. Cristea, Ramón A. González

“…These findings represent the first analysis of the proteomes of isolated RCs and not only enhance our understanding of nuclear organization during infection but also shed light on the complex interplay between viral and host factors within RCs.…”
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Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…Abstract Background Post-Acute COVID Syndrome (PACS) is a complex disorder that currently lacks effective evidenced-based therapies to manage it. …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…Conclusions Findings from the SSADHD Natural History Study converge with iPSC and animal model work focused on a common disorder within our IDDRC, deepening our knowledge of the pathophysiology and longitudinal clinical course of a complex neurodevelopmental disorder. This further enables the identification of biomarkers and changes throughout development that will be essential for upcoming targeted trials of enzyme replacement and gene therapy.…”
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Deep Neck Infections: The Effectiveness of Therapeutic Management and Bacteriological Profile by Geanina Bandol, Mihail Dan Cobzeanu, Mihaela Moscalu, Octavian Dragos Palade, Liliana Moisii, Florentina Severin, Emilia Patrascanu, Florin Mocanu, Andrei Ionut Roman, Bogdan Mihail Cobzeanu

“…<i>Conclusions</i>: Deep neck infection has a complex pathology, whose therapeutic management remains a challenge in order to reduce the length of hospitalization and mortality.…”
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Role of PI3K/AKT/mTOR signaling pathway and sirtuin genes in chronic obstructive pulmonary disease development by G. F. Korytina, L. Z. Akhmadishina, V. A. Markelov, Y. G. Aznabaeva, O. V. Kochetova, T. R. Nasibullin, A. P. Larkina, N. N. Khusnutdinova, N. Sh. Zagidullin, T. V. Victorova

“…Chronic obstructive pulmonary disease (COPD) is a multifactorial disease of the respiratory system which develops as a result of a complex interaction of genetic and environmental factors closely related to lifestyle. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…Benth. ex Kurz) powder (RSP) on three key immune-related genes; Suppressor of cytokine signaling 3 (SOCS3), the quiescence-related gene P20K (P20K), and the major histocompatibility complex Class IIβ (MHC class IIβ), gut morphology and growth performance of broiler chicks infected with Salmonella Gallinarum.MethodsTwo hundred and forty day-old Hubbard classic chickens were randomly assigned to four groups: non-challenged control (NC), and Salmonella Gallinarum challenge group (SGC), and two treatment groups fed a basic diet supplemented with 1.5% Rauwolfia serpentina powder (RSP) with SGC (RSP-1) and 3% RSP with SGC (RSP-2), respectively, from day 3 till 28 days of age. …”
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Geography and age drive racial and ethnic disparities in hospital mortality for paediatric community-acquired pneumonia in the United States: a retrospective population based cohor... by Cody-Aaron L. Gathers, Nadir Yehya, Anireddy Reddy, Paula M. Magee, Vanessa C. Denny, Michelle R. Mayeda, Amanda O’Halloran, Sanjiv D. Mehta, Stephanie Wanamaker, Jessica C. Fowler, Garrett Keim

“…Multivariable logistic regression, clustered by hospital and adjusting for sex, primary insurance payer, median household income quartile, urban identification, and the presence of a complex chronic condition(s), quantified the relationship between the joint exposure and all-cause mortality for paediatric community-acquired pneumonia. …”
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Presentations on How to Finance Iran's Higher Education Based on the Global Study Model by Ehsan Ehteshamnejad, Mehdi Pakzad Bonab, Mehdi Ramezani

“…The target population of this research is 30 people of the higher education complex in Iran, which was randomly selected from among the experts, managers and expert experts who have the opinion and possess this collection. …”
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Lightweight Tea Shoot Picking Point Recognition Model Based on Improved DeepLabV3+ by HU Chengxi, TAN Lixin, WANG Wenyin, SONG Min

“…Traditional neural network methods suffer from issues such as large model size, long training times, and difficulties in dealing with complex scenes. In this study, based on the actual scenario of the Xiqing Tea Garden in Hunan Province, proposes a novel deep learning algorithm was proposed to solve the precise segmentation challenge of famous and high-quality tea picking points.…”
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Ethnic and racial discrimination in maternal health care in Mexico: a neglected challenge in the search for universal health coverage by Edson Serván-Mori, Sergio Meneses-Navarro, Rocío García-Díaz, Diego Cerecero-García, David Contreras-Loya, Octavio Gómez-Dantés, Arachu Castro

“…Addressing these inequities requires the recognition of both observable and unobservable factors driven by discriminatory ideologies and the implementation of targeted measures to confront the complex interactions driving discrimination in maternal health care services for Indigenous women.…”
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Optimizing N-1 Contingency Rankings Using a Nature-Inspired Modified Sine Cosine Algorithm by Irnanda Priyadi, Novalio Daratha, Teddy Surya Gunawan, Kalamullah Ramli, Febrian Jalistio, Hazlie Mokhlis

“…This research advances state-of-the-art power system reliability assessment and optimization approaches, providing operators and planners with a robust tool for addressing complex contingency challenges. ABSTRAK: Memastikan keandalan dan kelestarian sistem tenaga elektrik adalah penting untuk mengekalkan operasi yang cekap dan tidak terganggu, terutamanya dalam menghadapi keadaan beban yang berubah-ubah dan kemungkinan kerosakan. …”
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