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29721
At-Tashbīh fī Khuṭub Khulafā’ ar-Rāshidīn (Dirāsah Balāghiyyah Bayāniyyah)
Published 2024-08-01“…The findings reveal a rich tapestry of similes that not only enhance the eloquence of the speeches but also serve to clarify complex ideas, reinforce moral teachings, and evoke emotional responses from listeners. …”
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29722
Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric...
Published 2025-02-01“…This study further demonstrated that iron transiently regulated T. vaginalis phosphatidylinositol-4-phosphate 5-kinase (TvPI4P5K) proteostasis and its complex formation with an active ADP ribosylation factor TvArf220, facilitating co-trafficking to the plasma membrane, crucial for PIP2 production. …”
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29723
TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles
Published 2025-02-01“…MMP inhibitor or proteinase treatment blocked EV-mediated SMAD signaling, suggesting that EVs require MMP activity to release the active TGF-β from its latent complex, a function also linked to the EV-mediated transfer of pro-migratory potential and ability of cancer cells to survive in the presence of cytotoxic drugs. …”
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29724
Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer
Published 2025-01-01“…Similarly, UCK2 was also observed to have a negative association with major histocompatibility complex (MHC) genes. We noted that UCK2 had significant correlations with the sensitivity to various anti-cancer drug.ConclusionWe have observed that UCK2 plays pivotal roles in prognosis and tumor immunity, and it is associated with DNA repair and cancer stemness. …”
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29725
Building resilient cattle through better management of buffalo health
Published 2023-11-01“…On the contrary, other acute diseases (clostridial, for example) or those caused by intracellular bacteria may have a reserved prognosis, developing complex pictures. This unique set defines that the buffalo species is not resistant to these diseases But, instead, resistant to many. …”
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29726
Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii
Published 2025-02-01“…Mengjie Wang,1,2 Yifei Zeng,1,2 Min Liu,1 Dongxiao Zhang,1 Di Zhao,1,2 Junyue Wang,1,2 Yongxin Liu,1,2 Wenjie Zhao1 1Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China; 2School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of ChinaCorrespondence: Dongxiao Zhang, Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Art Museum Back Street, Dongcheng District, Beijing, 100010, People’s Republic of China, Tel +86 13811077684, Email tzdx_thinking@126.comBackground: Cystic neutrophilic granulomatous mastitis (CNGM) poses a significant threat to the physical and mental health of women due to its increasing incidence, complex clinical manifestations. Developing an appropriate animal model will help further study the pathogenesis of CNGM.Methods: Seventy-two rats were randomly assigned to seven groups: group A (n=12, tissue suspension 0.2mL), group B (n=12, 1× 10^8 CFU/mL Corynebacterium kroppenstedtii (CK) suspension 0.1mL), group C (n=12, 1× 10^9 CFU/mL CK suspension 0.1mL), group D (n=12, tissue suspension 0.1mL + 1× 10^8 CFU/mL CK suspension 0.1mL), group E (n=12, tissue suspension 0.1mL + 1× 10^9 CFU/mL CK suspension 0.1mL), group F (n=6, phosphate buffer saline solution 0.1mL), and group G (n=6, physiological saline 0.1mL + Complete Freund’s adjuvant suspension 0.1mL). …”
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29727
Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy st...
Published 2025-01-01“…The study highlighted the complex interactions between the C2 subtype and fibroblasts through the MK signaling pathway, which may be closely related to tumor-associated fibroblasts and tumor progression. …”
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29728
Gambaran Elektrolit dan Gula Darah Pasien Kejang Demam yang Dirawat di Bangsal Anak RSUP Dr. M. Djamil Periode Januari 2010 - Desember 2012
Published 2013-09-01“…Most of the research samples are first febrile seizure (76.5%). Complex febrile seizure occurred in 64.7%. Most cases of febrile seizures occurred in the age group ≥ 6 months - <2 years, about 51%. …”
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29729
Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review
Published 2025-02-01“…The Medical Research Council’s PE framework of complex interventions was used to identify key PE components. …”
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29730
Genome-wide association analysis of composite sleep health scores in 413,904 individuals
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29731
Investigation on willingness of psychiatric nurses to engage in dementia nursing and influencing factors analysis (精神科护士从事失智症护理工作意愿调查及影响因素分析)...
Published 2022-01-01“…The main reasons for unwilling to engage in the nursing work of patients with dementia included: difficulty in communication with elderly dementia patients, high nursing risk and high incidence of accidents, complicated physical diseases associated with the elderly, rapid changes in the disease condition, complex illness, lack of professional ability, lack of sense of value and their own development direction, uneven pay and income. …”
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29732
Implementasi VPN Antar Cabang Menggunakan Teknologi SDWAN dengan Metode Load Balance (Studi Kasus: PT. Mitra Solusi Infokom)
Published 2023-02-01“…Abstract The rapid development of network communication, the process of managing and monitoring the network will be more complex. In companies that have branch offices that are geographically separated, a Wide Area Network (WAN) is needed as a communication, in this case there are problems ranging from speed, bandwidth, delay, and communication line connections (redundancy). …”
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29733
Loss of histone H3K27me3 up-regulates SLC7A11 in diffuse gastric cancer cells
Published 2025-01-01“…Among them, 56 genes displayed the most significant up-regulation (fold change in signal intensity ≥2, P<0.05), with notable enrichment in the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway. Specifically, the methionine transporter SLC7A5 and the cystine transporter SLC7A11 were found to have the highest expression levels in gastric cancer tissues. …”
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29734
Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations
Published 2025-01-01“…We purified the first catalytically active recombinant human core RAG1–RAG2 complex and tested it in the presence of the co-factor human HMGB1 protein for the gel-based biochemical RAG DNA cleavage assay. …”
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29735
Mapping and Analysis of Exit Strategy Research: A Bibliometrics and Systematic Review
Published 2024-06-01“…This knowledge gap can leave companies unprepared to navigate the complexities of exiting a market or business venture. …”
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29736
Le temple polygonal de la rue Lecointre à Reims/Durocortorum
Published 2022-11-01“…The northern zone of the ancient city seems to have been understood from the outset as the site of monumental and funerary complexes, even if it also housed spaces devoted to domestic and artisanal activities. …”
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29737
Polymorphic variants of the genes for enzymes of the antioxidant system, apoptosis and inflammation as potential predictors of myocardial infarction
Published 2024-11-01“…Myocardial infarction (MI) is a multifactorial polygenic disease that develops as a result of a complex interaction of numerous genetic factors and the external environment. …”
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29738
Call for Papers - Advancing Astropharmacy and Sports Pharmacy
Published 2025-02-01“…His research focuses on developing an innovative decision-support AI tool for personalized care aimed at optimizing treatments, enhancing the quality of life for individuals with chronic complex conditions, improving the overall quality of care, and reducing societal healthcare costs. …”
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29739
Toward a circular carbon economy: Production of green C1 compounds through high-temperature CO2 electrolysis
Published 2025-03-01“…Additionally, modulating operational temperatures and the H2/CO ratio emerges as a promising, albeit challenging, approach to enhance product yields, given the complex kinetics of CO2 reduction. Furthermore, reducing the costs associated with electrolyzer fabrication and electricity consumption is identified as a pivotal factor for the commercial viability of this technology. …”
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29740
Analisis Perbandingan Algoritma Machine Learning dan Deep Learning untuk Klasifikasi Citra Sistem Isyarat Bahasa Indonesia (SIBI)
Published 2023-08-01“…Sign Language Recognition is a complex classification problem to solve. Each sign language has its syntax and grammar. …”
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