Exploring seasonal dynamics of sea spray aerosol bioactivity: Insights into molecular effects on human bronchial epithelial cells by Zixia Liu, Emmanuel Van Acker, Maarten De Rijcke, Filip Van Nieuwerburgh, Colin Janssen, Jana Asselman

“…Sea spray aerosol (SSA) is a complex mixture of natural substances that can be inhaled by coastal residents. …”
Get full text

Managing Friends and Foes: Sanctioning Mutualists in Mixed‐Infection Nodules Trades off With Defense Against Antagonists by Camille E. Wendlandt, Saumik Basu, Angeliqua P. Montoya, Paige Roberts, Justin D. Stewart, Allison B. Coffin, David W. Crowder, E. Toby Kiers, Stephanie S. Porter

“…Understanding the conflicting selective pressures plants face in complex biotic environments will be crucial for breeding crop varieties that can maximize benefits from mutualists even when they encounter antagonists.…”
Get full text

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy by Danielle Sidsworth, Noah Tregobov, Noah Tregobov, Colin Jamieson, Jennifer Reutens-Hernandez, Joshua Yoon, Geoffrey W. Payne, Geoffrey W. Payne, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers

“…Alzheimer’s disease (AD) is a complex neurocognitive disorder. Early theories of AD sought to identify a single unifying explanation underlying AD pathogenesis; however, evolving evidence suggests it is a multifactorial, systemic disease, involving multiple systems. …”
Get full text

Advancing soil-structure interaction (SSI): a comprehensive review of current practices, challenges, and future directions by Imtiyaz Akbar Najar, Raudhah Ahmadi, Akeem Gbenga Amuda, Raghad Mourad, Neveen El Bendary, Idawati Ismail, Nabilah Abu Bakar, Shanshan Tang

“…It highlights advancements in analytical, numerical, and experimental modelling methods, such as finite element analysis and discrete element methods, and evaluates their effectiveness in capturing the complex interactions between soil and structural systems. …”
Get full text

Diagnostic delay of myositis: protocol for an integrated systematic review by Christine Phillips, Matthew Cook, Anne Parkinson, Jane Desborough, Tergel Namsrai, Anita Chalmers, Christine Lowe

“…Introduction Idiopathic inflammatory myopathies (IIM). described as ‘inflammatory myositis’, are a heterogeneous group of rare muscular autoimmune diseases characterised by skeletal muscle inflammation. Its complex characteristics with lack of accurate diagnostic tests, unified classification system and comprehensive widely used diagnostic criteria could lead to diagnostic delay. …”
Get full text

Exploring the Intersection of ADHD and Music: A Systematic Review by Phoebe Saville, Caitlin Kinney, Annie Heiderscheit, Hubertus Himmerich

“…The analysis revealed that individuals with ADHD often experience unique challenges in musical tasks, particularly those related to timing, rhythm, and complex auditory stimuli perception, though these deficits did not extend to rhythmic improvisation and musical expression. …”
Get full text

Effects of digital and non-digital parental distraction on parent-child interaction and communication by Souhir Chamam, Souhir Chamam, Alexia Forcella, Alexia Forcella, Nadia Musio, Nadia Musio, Florence Quinodoz, Florence Quinodoz, Nevena Dimitrova

“…These findings likely relate to complex factors related to young children's experiences and habits with parental screen use.…”
Get full text

MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache by Chiara Abagnale, Antonio Di Renzo, Giada Giuliani, Gabriele Sebastianelli, Francesco Casillo, Lucia Ziccardi, Vincenzo Parisi, Cherubino Di Lorenzo, Mariano Serrao, Francesca Caramia, Vittorio Di Piero, Gianluca Coppola

“…Abstract Background Neuroimaging studies have shown that hypothalamic/thalamic nuclei and other distant brain regions belonging to complex cerebral networks are involved in cluster headache (CH). …”
Get full text

Age-related differences in eye blink-related neural activity and functional connectivity during driving by Emad Alyan, Stefan Arnau, Stephan Getzmann, Julian Elias Reiser, Melanie Karthaus, Edmund Wascher

“…Driving is a complex task that requires effective neural processing and coordination, which degrade with aging. …”
Get full text

SFSCDNet: A Deep Learning Model With Spatial Flow-Based Semantic Change Detection From Bi-Temporal Satellite Images by K. S. Basavaraju, N. Sravya, Vibha Damodara Kevala, Shilpa Suresh, Shyam Lal

“…Existing deep learning-based methods, particularly those relying on triple-branch architectures, often struggle to accurately localize and predict changes in complex spatial environments characterized by diverse land-cover types. …”
Get full text

Analysis of the spatial pattern and causes of ecological environmental quality in Myanmar based on the RSEI model and the Geodetector-GCCM method by Shuangfu Shi, Shuangfu Shi, Shuangyun Peng, Shuangyun Peng, Zhiqiang Lin, Zhiqiang Lin, Bangmei Huang, Dongling Ma, Dongling Ma, Ziyi Zhu, Ziyi Zhu, Yilin Zhu, Yilin Zhu, Rui Zhang, Ting Li

“…It enriched the understanding of human-environment interactions within coupled systems and delved into the complex mechanisms and causal effects among multiple factors within the ecological system. …”
Get full text

Identifying pesticide mixtures at country-wide scale by Cairo, Milena, Monnet, Anne-Christine, Robin, Stéphane, Porcher, Emmanuelle, Fontaine, Colin

“…Wild organisms are likely exposed to complex mixtures of pesticides owing to the large diversity of substances on the market and the broad range agricultural practices. …”
Get full text

Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

“…Techniques that cost-effectively allow the enriching of the genome of interest from complex genome backgrounds for sequencing studies help immensely to perform genomic analyses. …”
Get full text

Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignant tumor characterized by a complex tumor microenvironment (TME) with significant heterogeneity, posing immense challenges for devising effective therapeutic strategies. …”
Get full text

Intersectional discrimination, exclusion and the socio-political economy of global mental health: A systematic scoping review of the literature by Rochelle A. Burgess, Sorcha Ní Chobhthaigh, Bijayalaxmi Biswal, Diana Ceccolini, Babatunde Fadipe, Denaneer Khan, Neena Aggarwal, Ishrat Pabla, Camila Solis, Ramya Pillutla, Piyali Sarkar, Eric Frasco, Valentina lemmi, Soumitra Pathare, Crick Lund

“…However, such frameworks face critique linked to their limited acknowledgement of structural determinants and the complex social processes which establish the patterns of disease. …”
Get full text

Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure by Ikeotunye Royal Chinyere, Pierce Bradley, Joshua Uhlorn, Joshua Eason, Saffie Mohran, Giuliana G. Repetti, Sherry Daugherty, Jen Watson Koevary, Steven Goldman, Jordan J. Lancaster

“…In vitro, engineered grafts exhibited responsiveness to beta-adrenergic receptor agonism/antagonism and SERCA inhibition and elicited complex molecular profiles. Conclusions. This hiPSC-CM-derived cardiac graft improved systolic and diastolic cardiac function in immune-competent CHF rats. …”
Get full text

Laser powder bed fusion of Ti6Al4V using low-cost high efficiency 450 nm diode point melting by Alkim Aydin, Erhan Cetin, S. Can Erman, Kamran Mumtaz

“…Laser Powder Bed Fusion (LPBF) is a commonly used Additive Manufacturing (AM) method for the production of geometrically complex metal components that are used in high-value sectors. …”
Get full text

Uncovering molecular mechanisms of soybean response to 12C6+ heavy ion irradiation through integrated transcriptomic and metabolomic profiling by Honglei Ren, Bixian Zhang, Chunlei Zhang, Xiulin Liu, Xueyang Wang, Fengyi Zhang, Kezhen Zhao, Rongqiang Yuan, Ahmed M. Abdelghany, Sobhi F. Lamlom

“…These findings elucidate soybeans' complex molecular reactions to ionizing radiation, helping us understand how radiation-induced genetic and metabolic alterations affect plant growth.…”
Get full text

Physical, Textural, Rheological, and Sensory Characteristics of Amaranth-Based Wheat Flour Bread by Sahreen Nasir, Farhana Mehraj Allai, Murtaza Gani, Shaiq Ganaie, Khalid Gul, Aabida Jabeen, Darakshan Majeed

“…Rheological parameters like complex viscosity, loss modulus, and storage modulus were also observed in all dough samples. …”
Get full text

Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments by Qiyao Liu, Tingyu Zhang, Yongan Ye, Xin Sun, Huan Xia, Xu Cao, Xiaoke Li, Wenying Qi, Yue Chen, Xiaobin Zao

“…A protein–protein interaction (PPI) network was constructed using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING), and hub genes were identified using Molecular Complex Detection (MCODE). LC was induced in rats and mice via intraperitoneal injections of diethylnitrosamine and carbon tetrachloride (CCl4) for 12 weeks. …”
Get full text