The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

“…Objective: Diabetic cardiomyopathy (DCM) is characterized by complex pathophysiological events. miRNAs play a role in the DCM. …”
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Analysis of marker substitutions in A/chicken/Astrakhan/2171-1/2020 H5N8 isolate of avian influenza virus recovered in the Astrakhan Oblast by N. G. Zinyakov, A. V. Andriyasov, Ye. V. Ovchinnikova, A. A. Kozlov, P. D. Zhestkov, D. B. Andreychuk, I. A. Chvala

“…Type A Н5N8 avian influenza virus was identified with complex PCR-based methods in the submitted samples. …”
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EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma by Di Li, Meng Li, Zhenjian Zhuo, Huiqin Guo, Weixin Zhang, Yile Xu, Hai-Yun Wang, Jiabin Liu, Huimin Xia, Huiran Lin, Jue Tang, Jing He, Lei Miao

“…Mechanistically, EDF1 was recruited as a coactivator to form the NF-κB/RelA/EDF1 complex, which further prevented the promoter region methylation of ST8SIA1, to elevate its transcription. …”
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Evaluating the Association Between Methylenetetrahydrofolate Reductase (Rs1801131 and Rs1801133) Gene Polymorphisms and Severity of Coronary Lesions in Patients With STEMI and NSTE... by Behnam Nazarzadeh, Saeedeh sadat Ghazanfari, Farzaneh Karimi, Seyed ali Moezibady, Fatemeh Salmani, Kazem Dastjerdi, Hamidreza Mohammadi

“…The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score is also an appropriate predictor for revascularization strategy in patients with complex CAD. The aim of this study is to investigate the correlation between rs1801131 and rs1801133 with the severity of coronary lesions in patients with ST‑Elevation Myocardial Infarction (STEMI) and Non‑ST‑Elevation Myocardial Infarction (NSTEMI) based on the SYNTAX score. …”
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Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study by Elif Baris, Izel Topaloglu, Elif Akalin, Emre Hamurtekin, Seray Kabaran, Ayse Gelal, Reyhan Ucku, Mualla Aylin Arici

“…Conclusions This research highlights FMS's complex nature, involving neurochemical, immunological, and nutritional factors. …”
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Impact of open femoral endarterectomy on treating multilevel iliac and common femoral artery occlusive disease by Suehyun Park, Taewan Ku, Deokbi Hwang, Woo-Sung Yun, Seung Huh, Hyung-Kee Kim

“…Overall, FE and additional thrombectomy reduced the TASC II classification of AIOD from complex lesions (TASC II C/D) to simple lesions (B or lesser) in 101 (95%) of 106 limbs. …”
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Symptom network analysis of insomnia-depression-anxiety-stigma in tuberculosis patients by Xiangmin Liu, Xue Qiu, Huizhen Lan, LiuYue Diao, Wei Huang, Yan Wen, Mei Feng, Mei Feng, Xiangdong Tang

“…BackgroundInsomnia, depression, anxiety, and stigma are prevalent and often coexist in patients with Tuberculosis (TB), potentially exacerbating one another. However, the complex intrinsic associations among these four disorders remain unclear, particularly concerning the role of stigma in relation to the other disorders.MethodsA cross-sectional study was conducted at West China Hospital and the Fourth People’s Hospital of Guangxi from November 2023 to June 2024. …”
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Low Thermal Resistance of Diamond‐AlGaN Interfaces Achieved Using Carbide Interlayers by Henry T. Aller, Thomas W. Pfeifer, Abdullah Mamun, Kenny Huynh, Marko Tadjer, Tatyana Feygelson, Karl Hobart, Travis Anderson, Bradford Pate, Alan Jacobs, James Spencer Lundh, Mark Goorsky, Asif Khan, Patrick Hopkins, Samuel Graham

“…The findings underscore the efficacy of interlayer engineering in enhancing thermal transport and demonstrate the importance of innovative measurement techniques in accurately characterizing complex thermal interfaces. This study provides a foundation for future research in improving thermal properties of semiconductor devices through interface engineering and advanced measurement methodologies.…”
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Identification of key chromium resistance genes in Cellulomonas using transcriptomics by Hongmei Sun, Yongdong Li, Shengchao Gao, Guangchuan Shi, Lianbin Cao, Xinya Li, Tong Li, Tongbiao Li, Mingcheng Wang, Enzhong Li, Junhe Liu, Hongxia Ni, Yi Chen, Ying Liu

“…Proton pump subunit encoding genes atpA, atpB, atpE, atpF, and atpH, as well as sodium-hydrogen antiporter subunit encoding genes mnhA and mnhC were upregulated, it may be involved in the extracellular proton secretion to reduce Cr(VI). Iron complex transport system substrate-binding protein encoding gene ABC.FEV.S, vacuolar iron transporter encoding gene VIT, FMN reductase gene encoding gene ssuE, and quinone oxidoreductase encoding genes qor and qorB were upregulated to reduce Cr(VI) in the intracellular. …”
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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses by Lifen Liu, Yang Liu, Rui Li, Yue Teng, Shuyang Zhao, Jinhong Chen, Changjiang Li, Xinyu Hu, Lin Sun

“…ABSTRACT Background Post‐traumatic stress disorder (PTSD) is a complex psychiatric condition that emerges following exposure to trauma and significantly affects daily functioning. …”
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Metal-free production of natural blue colorants through anthocyanin–protein interactions by Wenxin Wang, Peiqing Yang, Fuqing Gao, Yongtao Wang, Zhenzhen Xu, Xiaojun Liao

“…Anthocyanins (ACNs) are known for providing blue colors in plants, and metal complexation with acylated ACNs remains the primary strategy to generate stable blue hues. …”
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La photogrammétrie subaquatique pour l’étude des habitats en cours d’eau by Guillaume FORGET, Alan BAZIN, Karl KREUTZENBERGER, Émilien LASNE, Jean-Marc ROUSSEL, Alain CRAVE, Olivier DÉZERALD

“…Cependant, la caractérisation précise, non invasive et non destructive de ces habitats est une tâche complexe et coûteuse en temps humain et matériel. Pour étudier les habitats, nous avons développé une approche innovante, non invasive et non destructive basée sur la photogrammétrie subaquatique consistant à quantifier rapidement, et de manière semi-automatique, les caractéristiques du substrat (e.g., microtopographie et taille des macro-éléments organiques ou minéraux). …”
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Study on the drying characteristics of green pellets of ultrafine iron ore concentrate by Wen B.-L., Zhang X.-P., Liu D.-L., Li J.-X., Sun X.-D., Yang J.-L.

“…Ultrafine iron ore concentrate pose challenges such as poor pellet formation performance, low-bursting temperature, and a complex drying thermal regime. To examine the drying characteristics of green pellets made from ultrafine iron ore concentrate, the Weibull distribution function and Dincer model were employed to fit and analyze the corresponding drying curve. …”
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Hyssopus cuspidatus volatile oil: a potential treatment for steroid-resistant asthma via inhibition of neutrophil extracellular traps by Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin, Jin-Bo Fang

“…Network pharmacology and molecular docking were employed to uncover the complex mechanisms of HVO in treating SRA and predict potential effective compounds in HVO. …”
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Pain management in trauma: the need for trauma-informed opioid prescribing guidelines by Ben L Zarzaur, Suresh Agarwal, Colleen Trevino, Amelia Baltes, David M Horton, Julia Malicki, Randall T Brown

“…Background/objectives Surgical populations and particularly injury survivors often present with complex trauma that elevates their risk for prolonged opioid use and misuse. …”
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Interleukin-32 positive immune and resident cells in kidney samples from lupus patients: a pilot study by Simona Truglia, Simona Truglia, Francesco Ciccia, Silvia Mancuso, Antonella Capozzi, Aroldo Rizzo, Francesca Romana Spinelli, Fulvia Ceccarelli, Tania Colasanti, Cristina Garufi, Francesca Miranda, Maurizio Sorice, Cristiano Alessandri, Fabrizio Conti

“…IntroductionLupus nephritis (LN), caused by immune complexes produced in situ or deposited from the bloodstream, is one of the most severe features of Systemic Lupus Erythematosus (SLE) leading to an increased morbidity and mortality. …”
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Recent advances in the application of Mendelian randomization to chronic kidney disease by Chaofan Wen, Lanlan Chen, Dan Jia, Ziqi Liu, Yidan Lin, Guan Liu, Shuo Zhang, Baoshan Gao

“…Utilizing Mendelian randomization, researchers have begun to untangle the complex causal relationships underlying CKD. This review delves into the advances and challenges in the application of MR in the field of nephrology, shifting from a mere summary of its principles and limitations to a more nuanced exploration of its contributions to our understanding of CKD.Methods Key findings from recent studies have been pivotal in reshaping our comprehension of CKD. …”
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Decision-making regarding place of end-of-life care for children with life-limiting and life-threatening conditions: a systematic integrative review by Ashleen Crowe, Fiona Hurley, Gemma Kiernan, Helen Kerr, Yvonne Corcoran, Jayne Price, Joanne Reid, Eileen Courtney, Tracey McConnell, Patricia McNeilly, Veronica Lambert

“…Conclusion There are a complex range of factors surrounding decision-making regarding place of end-of-life care for children with life-limiting and life-threatening conditions. …”
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3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

“…However, the limited representation of a complex microenvironment in implanted accepter hampers a comprehensive understanding of long-term maintenance of tissue-engineering organoids, especially in liver. …”
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Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure by Birgitte Carbuhn Larsen, MD, Martin Christian Harmsen, MD, Henrik Vase, MD, PhD, Jens Erik Nielsen-Kudsk, MD, DMSc, Asger Andersen, MD, PhD

“…Background: A patent foramen ovale (PFO) has a complex anatomy, and evaluating the size before closure may be challenging. …”
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