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21761
Reflexive Methods of Knowledge in Educational Activities: Phenomenological Hermeneutics
Published 2019-07-01“…Reflexive abilities as the mechanism and instrument of knowledge, which assist a personality to understand himself or herself, to comprehend own feelings, actions, acts and complex external realities, in most cases remain unaccounted in educational process and when analysing and evaluating the results.The aim of the article was to justify the need to form reflexive skills of knowledge in students through a combination of phenomenological and hermeneutical methods in daily pedagogical practice.Methodology and research methods. …”
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21762
Youth Involvement in Pornography and Academic Engagement in Selected Secondary Schools in Kabale Municipality.
Published 2024“…The study concluded that the existing relationship between pornography and youth academic engagement is complex and multi-faceted. Addressing this issue requires comprehensive sex education, media literacy programs, and open dialogues to empower youths of school-going age to make informed choices. …”
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21763
Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway
Published 2024-12-01“…Next, we integrated the results obtained from the degree algorithm provided by the Cytohubba plug-in, Molecular complex detection (MCODE) plug-in, weighted gene correlation network analysis (WGCNA), and Least absolute shrinkage and selection operator (LASSO) logistic regression. …”
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21764
Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress...
Published 2025-01-01“…This may lead to the development of a double-hit preclinical model in despair-based depression, a better understanding of these complex conditions, and more effective therapeutic strategies by elucidating the relationship between Trp metabolism and PTSD pathogenesis.…”
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21765
Effectiveness of a specialist palliative home care nurse–patient consultation followed by an interprofessional telephone case conference compared with usual care among patients wit...
Published 2022-07-01“…Outpatient palliative care can help to reduce hospitalisation rate by up to 50%. Due to the complex medical conditions and prognostic uncertainty of the course of CNMD, early interprofessional care planning among general practitioners who provide general palliative care and specialist palliative home care (SPHC) teams seems mandatory. …”
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21766
Use of cannabis during pregnancy and birth outcomes in an Aboriginal birth cohort: a cross-sectional, population-based study
Published 2016-02-01“…The reasons for disparities are complex and multifactorial. We aimed to assess the extent to which adverse birth outcomes are associated with maternal cannabis use and exposure to stressful events and social health issues during pregnancy.Design/setting Cross-sectional, population-based survey of women giving birth to Aboriginal babies in South Australia, July 2011–June 2013. …”
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21767
Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccha...
Published 2022-07-01“…Participants randomised to PCV13 and placebo will also be randomised to one of two clinically relevant SPN3 strains from distinct lineages within clonal complex 180, clades Ia and II, creating five study groups. …”
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21768
Effect of photobiomodulation as preventive treatment of diabetic foot ulcer: randomised, controlled, double-blind, clinical trial protocol
Published 2025-01-01“…Assessments will be performed at the beginning of the study, after 30 days (clinical examination) and after 60 days (clinical examination, assessment of peripheral neuropathy (PN) and peripheral artery disease (PAD), blood and urine examinations and quality of life).Ethics and dissemination This protocol received approval from the Human Research Ethics Committee of Nove de Julho University and the Mandaqui Hospital Complex (certificate number: 66098522.0.3001.5511; final approval date: 22 June 2023). …”
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21769
Assessment of vitamin D status in obese and non-obese patients: A case-control study
Published 2025-01-01“…The pathophysiology behind this association is complex. Further research is needed to clarify the relationship between vitamin D, adipose tissue, and the other components of metabolic syndrome.…”
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21770
Exploring Innovative Approaches for the Analysis of Micro- and Nanoplastics: Breakthroughs in (Bio)Sensing Techniques
Published 2025-01-01“…Chemical analyses, such as Fourier transform infrared (FTIR) and Raman spectroscopy, offer molecular specificity but face challenges with smaller particle sizes and complex matrices. Thermal analytical methods, including pyrolysis gas chromatography–mass spectrometry (Py-GC-MS), provide compositional insights but are destructive and limited in morphological analysis. …”
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21771
How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh?
Published 2025-02-01“…Plant leaf functional traits significantly influence carbon cycling in tropical forests, though the relationships between these traits and carbon stocks are complex. The present study investigates the role of leaf functional traits, i.e., specific leaf area (SLA), leaf dry matter content (LDMC), leaf width, and leaf thickness—on above-ground tree carbon (AGTC) stocks in two forest protected areas (PA) in northeast Bangladesh: Khadimnagar National Park (KNP) and Rema Kalenga Wildlife Sanctuary (RKWS). …”
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21772
Comprehensive metabolite profiling and evaluation of anti-nociceptive and anti-inflammatory potencies of Nypa fruticans (Wurmb.) leaves: Experimental and in-silico approaches
Published 2025-02-01“…Molecular dynamics simulations (MDS) confirmed the stability of the protein-ligand complexes. Two phytochemicals, (−) Epicatechin (CID 72276) and Quercetin (CID 5280343), outperformed the standard anti-inflammatory drug, diclofenac sodium, in MDS studies. …”
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21773
Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber
Published 2024-11-01“…This polymer covalently attaches to PARP1, which leads to its dissociation from the complex with damaged DNA and stimulation of the repair process. …”
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21774
Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
Published 2022-06-01“…Managing HF after hospitalization is a complex cognitive task and an increased focus on mental status in the acute care setting prior to discharge is needed to improve HF management and transitional care, mitigate adverse outcomes, and reduce healthcare costs.…”
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21775
Dissolved Mn(III) is a key redox intermediate in sediments of a seasonally euxinic coastal basin
Published 2025-02-01“…The role of organically complexed dissolved Mn(III) (dMn(III)-L) as an electron acceptor and donor in marine environments is still incompletely understood. …”
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21776
Eco-benign synthesis of multifunctional silver nanoparticles using leptochloa fusca for enhanced biomedical and catalytic applications
Published 2025-01-01“…The hyperchromism observed in the UV–vis absorption spectra, as well as changes in the FTIR spectra of ssDNA and BSA upon interaction with LF-AgNPs, indicate the formation of LF-AgNPs–ssDNA and LF-AgNPs–BSA complexes. This type of binding results in conformational changes in ssDNA and BSA structures and therefore LF-AgNPs hold potential for numerous applications like drug delivery, anticancer agents and receptor targeting. …”
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21777
Temperature-dependent toxicity and mechanisms of florfenicol on the embryonic development of marine medaka (Oryzias melastigma)
Published 2025-01-01“…Furthermore, the key findings of this study reveal the complex interactions between florfenicol and temperature and emphasize the need to consider temperature when identifying toxicity and mechanisms, as well as the ecological risk assessment of florfenicol in marine environments.…”
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21778
Microalgae diversity in several different sub-habitats
Published 2022-10-01“…BACKGROUND AND OBJECTIVES: Biodiversity is the variety of life that exists on Earth, including all the organisms, species, and populations that come together in a complex manner to form communities and ecosystems. …”
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21779
Bottom Trawling and Multi‐Marker eDNA Metabarcoding Surveys Reveal Highly Diverse Vertebrate and Crustacean Communities: A Case Study in an Urbanized Subtropical Estuary
Published 2024-11-01“…However, monitoring these complex ecosystems using conventional trawling methods is destructive, costly, and labor‐intensive. …”
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21780
Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention
Published 2025-03-01“…Kinetic analyses further elucidated citrulline's non-competitive inhibition pattern while molecular dynamics analysis afforded assessment of the binding stability of citrulline with PDE5, both providing insights into its mechanism of action. Citrulline-PDE5 complex had a higher negative binding free energy (-45.06 ± 4.69 kcal/mol) relative to the conventional drug (sildenafil) (-13.86±10.23 kcal/mol). …”
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