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21581
Nursing postgraduates’ innovative behaviour, influencing factors and educational requirements: a national cross-sectional study
Published 2025-01-01“…Abstract Background Innovative behaviours are important for nursing postgraduates who are a significant reserve for future nursing career, thinking critically, utilizing technologies and solving complex problems. In nursing undergraduates’ education, innovative behaviour is closely linked with the development of professional identity. …”
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21582
Association between the subclinical level of problematic internet use and habenula volume: a look at mediation effect of neuroticism
Published 2025-02-01“…Moreover, neuroticism was shown to mediate the relationship between Hb volume and PIU tendency, offering valuable insight into the complexities of this interaction.…”
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21583
Response of YPM x Ross 708 male broilers to diets containing varying inclusions of phytase, calcium butyrate, and bacitracin methylene disalicylate during the grower and finisher p...
Published 2025-03-01“…Overall, broiler intestinal health and physiology were influenced by CB and BMD depending on phytase concentration, demonstrating the complex interactions between these feed additives.…”
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21584
Impaired Fibrinolysis in Angiographically Documented Coronary Artery Disease
Published 2015-01-01“…It acts by blocking the formation of a ternary complex of plasminogen, fibrin, and tissue plasminogen activator (t-PA). …”
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21585
Higher education students' perceptions of ChatGPT: A global study of early reactions.
Published 2025-01-01“…They found it useful for simplifying complex information and summarizing content, but less reliable for providing information and supporting classroom learning, though some considered its information clearer than that from peers and teachers. …”
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21586
Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway
Published 2025-01-01“…Protein–protein interaction (PPI) analysis combined with molecular complex detection (MCODE) identified six hub genes, namely, Ddit3, Atf3, Sesn2, Trib3, Ppp1r15a, and Gadd45a. …”
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21587
Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland
Published 2025-01-01“…Results: E. coli E230738 genome was identified to belong to phylogroup-A/ST10 complex and to harbour 63 ARGs, 17 of which acquired. …”
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21588
Management of CAR-T cell therapy in patients with multiple myeloma: a systematic review and expert consensus in Australia
Published 2025-01-01“…BackgroundRegulatory bodies have recently approved chimeric antigen receptor (CAR)-T cell therapies for patients with multiple myeloma (MM), but the treatment process involves complex decision making. To support the introduction of these therapies, we aimed to establish consensus expert opinion on best practices of all aspects of the management of patients with MM undergoing CAR-T cell therapy in Australia.MethodsWe conducted a modified RAND/UCLA two-round Delphi panel informed by a systematic literature review (SLR). …”
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21589
Multidimensional analysis and enhancement strategies for ecological environment quality at the county level under dual carbon goals: a case study of Shaanxi Province, China
Published 2025-01-01“…However, most studies on ecological environment quality (EEQ) focus on urban areas, with limited attention to county-level analyses, particularly regarding the complex interactions between climate, topography, and human activities. …”
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21590
Artificial intelligence conversational agents in mental health: Patients see potential, but prefer humans in the loop
Published 2025-01-01“…About half endorsed negative opinions, citing AI’s lack of empathy, technical limitations in addressing complex mental health situations, and data privacy concerns. …”
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21591
Association between body composition indices and vascular health: a systematic review and meta-analysis
Published 2025-01-01“…Conclusion This meta-analysis highlights the complex relationship between body composition and vascular health. …”
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21592
HINT1 suppression protects against age-related cardiac dysfunction by enhancing mitochondrial biogenesis
Published 2025-03-01“…We also showed that activity of the BAF chromatin remodeling complex is repressed by HINT1, whose expression in heart increases with age, leading to decreased transcription of Tfam, which promotes mitochondrial biogenesis. …”
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21593
Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning
Published 2025-01-01“…IntroductionType 2 diabetes (T2D) is a complex metabolic disorder with significant global health implications. …”
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21594
“Holding on to Hope”: follow up qualitative findings of a tobacco treatment intervention for people experiencing mental health conditions
Published 2025-01-01“…Quitting tobacco can be harder for people experiencing SMI due to higher levels of nicotine dependence, more severe withdrawal, and many other complex factors. The Quitlink study was a randomized controlled trial combining a tailored 8-week Quitline intervention delivered by dedicated Quitline counsellors plus combination nicotine replacement therapy for people who experience SMI. …”
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21595
Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalab...
Published 2022-07-01“…Introduction Delirium is a complex condition in which altered mental state and cognition causes severe distress and poor clinical outcomes for patients and families, anxiety and stress for the health professionals and support staff providing care, and higher care costs. …”
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21596
Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation
Published 2025-02-01“…Increased accumulated charge facilitates the development of complex neuronal morphologies and axonal ramification, outperforming exogenous neurotrophic factors. …”
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21597
Disease-Related Knowledge, Stress, and Quality of Life of Parental Caregivers of Children with Cleft Lip and Palate in a Selected Hospital in Ho Chi Minh City, Vietnam
Published 2025-03-01“…Parental caregivers, particularly mothers, face considerable challenges in managing complex treatment pathways and addressing their children's multifaceted needs. …”
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21598
High-Performance Photocatalytic Multifunctional Material Based on Bi<sub>4</sub>Ti<sub>3</sub>O<sub>12</sub>-Supported Ag and Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> for Organic D...
Published 2024-12-01“…With the rapid development of modern science and technology and the diversification of social needs, traditional single-performance materials struggle to meet the complex and changeable application scenarios. To address the multifaceted requirements of biomedical applications, such as disease diagnosis and treatment, scientists are dedicated to developing new multifunctional biomaterials with multiple activities. …”
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21599
Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning
Published 2025-01-01“…Moreover, PLAC8 overexpression was found to promote the proliferation of urothelial cells without affecting their migratory ability by inhibiting the Akt/mTOR/PI3K signaling pathway.ConclusionsOur study identifies potential diagnostic candidate genes and reveals the complex immune landscape associated with IC/BPS. Among them, PLAC8 is a promising diagnostic biomarker that modulates the immune response in patients with IC/BPS, which provides new insights into the future diagnosis of IC/BPS.…”
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21600
The Conceptual Domain of Hunting and Its Negative Representation in Love: A Cognitive-Cultural Analysis
Published 2024-09-01“…These representations are complex, but from a cognitive perspective, their significance lies in how they draw upon the source domain of hunting, shaping the thinking and reasoning about love and seduction in the texts under study. …”
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