Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

“…Abbreviations: SCI: spinal cord injury; CNS: central nervous system; YLDs: years of life lived with disability; lncRNAs: long noncoding RNAs; mRNAs: messenger RNAs; DE: differentially expressed; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: gene set enrichment analysis; RIN: Renewable Identification Number; PCA: principal component analysis; PPI: protein–protein interaction; MF, molecular function; BP: biological process; CC: cellular component; MCODE: molecular complex detection…”
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Super Typhoons Simulation: A Comparison of WRF and Empirical Parameterized Models for High Wind Speeds by Haihua Fu, Yan Wang, Yanshuang Xie, Chenghan Luo, Shaoping Shang, Zhigang He, Guomei Wei

“…Current typhoon modeling primarily falls into two categories: (1) complex simulations based on fluid dynamics and thermodynamics, and (2) empirical parameterized models. …”
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Towards PErsonalised PRognosis for children with traumatic brain injury: the PEPR study protocol by Jaap Oosterlaan, Marsh Königs, Job B M van Woensel, Marc Engelen, Marjan E Steenweg, Petra J W Pouwels, Cece C Kooper, Hilgo Bruining, Arne Popma, Dennis R Buis, Maayke Hunfeld

“…However, outcome varies between patients and is mediated by complex interplay between demographic factors, premorbid functioning and (sub)acute clinical characteristics. …”
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Effects of Different River Crab <i>Eriocheir sinensis</i> Polyculture Practices on Bacterial, Fungal and Protist Communities in Pond Water by Yun Bao, Bing Li, Rui Jia, Linjun Zhou, Yiran Hou, Jian Zhu

“…The PC group altered the co-occurrence networks of bacteria, fungi, and protist, leading to more complex and stable communities of fungi and protist. …”
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Implication of tumor morphology and MRI characteristics on the accuracy of automated versus human segmentation of GBM areas by Valeria Cerina, Chiara Benedetta Rui, Andrea Di Cristofori, Davide Ferlito, Giorgio Carrabba, Carlo Giussani, Gianpaolo Basso, Elisabetta De Bernardi

“…Conversely, on less common tumors with more complex tissue distribution and infiltrative behavior, manual segmentation works better than BraTS-Toolkit and DeepBraTumIA, and image quality has a larger impact on automatic segmentation performance. …”
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Multidrug Resistance Tuberculosis in the Context of Co-Infection in Ethiopia: A Systematic Review and Meta-Analysis by Bezawit Kassaw Hailu, Yitayew Demessie, Abebe Tesfaye Gessese, Gashaw Getaneh Dagnaw, Haileyesus Dejene

“…These findings highlight the complex interplay between MDR-TB and other co-infections, posing significant challenges for clinical management and public health in Ethiopia. …”
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease by D. Luke Fischer, Marissa Menard, Omar Z. Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard E. Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli-Daley

“…Immunofluorescence for major-histocompatibility complex class 2 (MHCII) and ionized calcium binding adaptor molecule 1 (Iba1) also was performed because inflammation is an additional pathological hallmark of LBDs, and they were a positive control for two markers known to colocalize. …”
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OMERACT GCA phantom project: validation of a 3D-printed ultrasound training phantom for diagnosis of giant cell arteritis by Annamaria Iagnocco, Christian Dejaco, Richard J Wakefield, Stavros Chrysidis, Sara Monti, Thomas Daikeler, Esperanza Naredo, Lene Terslev, Wolfgang A Schmidt, Alojzija Hočevar, Christina Duftner, Chetan Mukhtyar, Valentin Sebastian Schäfer, Kate Smith, Eugenio De Miguel, Marcin Milchert, Andreas P Diamantopoulos, Pierluigi Macchioni, Uffe Møller Døhn, George A Bruyn, Verena Tischler, Wolfgang Hartung, Markus Aschwanden, Giuseppe Germanò, Aaron Juche, Rositsa Karalilova, Dennis Boumans, Kresten Krarup Keller, Luca Seitz, Berit Nielsen, Tobias Schremmer, Florian Recker, Cees Haagsma, Pantelis Karakostas, Borsha Sarker

“…Due to difficulties with the delineation of the intima-media complex, the parietal branch of the phantoms was modified, and a second round was conducted. …”
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Exploring the application of knowledge transfer to sports video data by Shahrokh Heidari, Gibran Zazueta, Riki Mitchell, David Arturo Soriano Valdez, Mitchell Rogers, Mitchell Rogers, Jiaxuan Wang, Ruigeng Wang, Marcel Noronha, Alfonso Gastelum Strozzi, Mengjie Zhang, Patrice Jean Delmas, Patrice Jean Delmas

“…For example, ZSL in player re-identification (a crucial step in more complex sports behavioral analysis) involves re-identifying players in sports videos without having seen examples of those players during the training phase. …”
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The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility by E. Di Zazzo, A. Feola, C. Zuchegna, A. Romano, C. F. Donini, S. Bartollino, C. Costagliola, R. Frunzio, P. Laccetti, M. Di Domenico, A. Porcellini

“…We demonstrated that phosphorylation of p85αPI3KS83 modulates the formation of the p85αPI3K/IRS-1 complex and its subcellular localization influencing the kinetics of the insulin signaling both on MAPK-ERK and AKT pathways. …”
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Combined surgical and interventional cardiology approach for central venous access salvage in children with intestinal failure: A case series by Emily Byrd, M. Jake Petersen, Minna M. Wieck, Frank Ing, Shinjiro Hirose

“…Methods: This is a retrospective review of six pediatric patients with intestinal failure (IF) and long-term total parenteral nutrition (TPN) dependence who underwent one or more hybrid procedures for achieving complex vascular access, vascular mapping, and/or salvage of vascular access sites. …”
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Advancing Pediatric Surgery: The Use of HoloLens 2 for 3D Anatomical Reconstructions in Preoperative Planning by Marco Di Mitri, Annalisa Di Carmine, Simone D’Antonio, Benedetta Maria Capobianco, Cristian Bisanti, Edoardo Collautti, Sara Maria Cravano, Francesca Ruspi, Michele Libri, Tommaso Gargano, Mario Lima

“…Conclusions: Despite some challenges in ease of use, HoloLens 2 showed promising results in reducing the learning curve for complex procedures. This study underscores the transformative potential of mixed reality technology in pediatric surgery, advocating for further research and development to integrate these advancements into routine clinical practice.…”
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Can Cryptogonimids of the Same Genus Influence Each Other’s Level of Genetic Variation? by Ekaterina S. Tokarskaya, Yulia V. Tatonova, Haneef Ahmed Amissah, Polina G. Shumenko, Mikhail Yu. Shchelkanov

“…To uncover the dynamics driving these observations, we propose the approach of expanding sampling, broader genetic marker analyses, and investigations of varied host populations that could elucidate the complexities of the <i>Exorchis</i> species genetic variability and evolutionary dynamics.…”
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The role of microbial enzymes β-glucanase and α-amylase in optimising feed production for poultry by Zhanar Narmuratova, Raushan Blieva, Zhanara Suleimenova, Nurlan Akhmetsadykov, Gulbakhyt Zhumagalieva

“…The results emphasised not only the high precision of the study, but also the effectiveness of the enzymes in improving feed utilisation and maintaining bird performance under altered dietary conditions. The study of enzyme complex in feeds is of practical importance to the poultry industry, as it confirms the efficacy of enzyme supplementation in improving feed utilisation and maintaining bird performance under altered diets. …”
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Establishment of wetland conservation networks in response to climate change and anthropogenic activities: A case study from the Liaohe River Basin in Liaoning Province, China by Kexin Chen, Shuxiu Liang, Pifu Cong, Zhaochen Sun

“…The wetland conservation network under the SSP5-RCP8.5 climate scenario was found to be more complex, with more conservation areas compared to the SSP1-RCP2.6 climate scenario. …”
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Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms by M. A. Kleshchev, A. V. Maltseva, E. A. Antropova, P. S. Demenkov, T. V. Ivanisenko, Y. L. Orlov, H. Chao, M. Chen, N. A. Kolchanov, V. A. Ivanisenko

“…Wheat adaptation to water deficit is ensured by complex molecular genetic mechanisms, including the coordinated work of multiple genes regulated by transcription factors and signaling non-coding RNAs, particularly microRNAs (miRNAs). miRNA-mediated regulation of gene expression is considered one of the main mechanisms of plant resistance to abiotic stresses. …”
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SFMHANet: Surface Fitting Constrained Multidimensional Hybrid Attention Network for Aero-Optics Thermal Radiation Effect Correction by Yu Shi, ShanLin Niu, Lei Wang, Liang Ye, YaoZong Zhang, HanYu Hong

“…In practical application scenarios, the aero-optical thermal radiation patterns in degraded images are not fixed, and types of aero-optics thermal radiation are more variable and complex. In order to handle multiple types of aero-optics thermal radiation effects effectively and to combine the advantages of image prior constraints and deep learning networks, we propose a surface fitting constrained multidimensional hybrid attention aero-optics thermal radiation correction network (SFMHANet) in this article. …”
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How to Reduce Delayed Gastric Emptying After Pancreatoduodenectomy: A Systematic Literature Review and Meta-Analysis by Artur Rebelo, MD, Randi Kresse, Yoshiaki Sunami, PhD, Ulrich Ronellenfitsch, MD, Jörg Kleeff, MD, Johannes Klose, MD

“…Although these results are partially based on observational studies, they contribute valuable insights to the current understanding of interventions impacting DGE in these complex procedures.…”
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CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris by Kaidi Chen, Gulikezi Maimaitirexiati, Qiannan Zhang, Yi Li, Xiangjian Liu, Hongting Tang, Xiang Gao, Bo Wang, Tao Yu, Shuyuan Guo

“…However, the lack of convenient and efficient genome engineering tools has hindered further applications of P. pastoris, especially in complex and multistep metabolic engineering scenarios. …”
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Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β,... by André L. F. Sampaio, Jesmond Dalli, Vincenzo Brancaleone, Fulvio D'Acquisto, Mauro Perretti, Carmen Wheatley

“…In resolution, 24 h after LPS, HOCbl completely abrogates a major late mediator of sepsis mortality, high mobility group box 1 (HMGB1) mRNA, inhibits iNOS mRNA, and attenuates LPS-induced hepatic inhibition of eNOS mRNA, whilst showing increased, but still moderate, NOS activity, relative to LPS only. experiments (LPS+D-Galactosamine) HOCbl afforded significant, dose-dependent protection in mice Conclusions. HOCbl produces a complex, time- and organ-dependent, selective regulation of NOS/•NO during endotoxaemia, corollary regulation of downstream inflammatory mediators, and increased survival. …”
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