Leveraging mRNA technology for antigen based immuno-oncology therapies by Wei Zheng, Michele Ceccarelli, Charalampos S Floudas, Siranush Sarkizova

“…The identification and prioritization of patient-specific tumor neoantigens are based on advanced computational algorithms taking advantage of the profiling with next-generation sequencing considering factors involved in human leukocyte antigen (HLA)-peptide-T-cell receptor (TCR) complex formation, including peptide presentation, HLA-peptide affinity, and TCR recognition. …”
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REGAIN STUDY: Retrospective Study to Assess the Effectiveness, Tolerability, and Safety of Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnant Women by Saleema Wani, Mariyam Noushad, Shabana Ashiq

“…Iron deficiency anemia (IDA) during pregnancy arises because of preexisting inadequate stores or complex physiological changes and can lead to serious maternal and fetal complications. …”
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Presenting a comprehensive multi-scale evaluation framework for participatory modelling programs: A scoping review. by Grace Yeeun Lee, Ian Bernard Hickie, Jo-An Occhipinti, Yun Ju Christine Song, Adam Skinner, Salvador Camacho, Kenny Lawson, Adriane Martin Hilber, Louise Freebairn

“…<h4>Introduction</h4>Systems modelling and simulation can improve understanding of complex systems to support decision making, better managing system challenges. …”
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Using the Circular Economy to Mitigate the Global Electronic Waste Challenge: A Systematic Literature Review Approach by Mfowabo Maphosa, Vusumuzi Maphosa

“…The study recommends that emerging economies should embrace the circular economy and integrate the informal sector for e-waste collection, sorting, and less complex recycling, while the formal sector conducts high-end recycling. …”
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Robust Identification of Vegetation Change Using Shapelet-Based Temporal Segmentation of Landsat Time-Series Stacks: A Case Study in the Qilian Mountains by Lipeng Jiao, Randolph H. Wynne

“…Although many algorithms have been developed for monitoring annual vegetation change, most require complex controlling parameters or can only detect abrupt forest disturbances. …”
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Investigating Feed-Forward Back-Propagation Neural Network with Different Hyperparameters for Inverse Kinematics of a 2-DoF Robotic Manipulator: A Comparative Study by Rania Bouzid, Jyotindra Narayan, Hassène Gritli

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Mitigation of human factor in tomographic post processing of additive manufactured critical parts for aviation application by Stefano Benuzzi, Davide Borghi, Maria Grazia Righi, Natanaele Galavotti, Fabio Esposito

“… Over the past decade, the development of the additive manufacturing process resulted in the manufacture of parts with increasingly complex geometries. The design freedom that Additive Manufacturing allows, enables the designer to develop increasingly optimized parts, capable of joining different geometries (lattice structures, thick walls, geometries optimized for heat dissipation) on a scale that can vary significantly depending on the required application. …”
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The Country-of-Origin Effect on the Reputation of Russian Metallurgical Products in Central Asian Markets by G. A. Savchuk, V. A. Frants, D. S. Saidmagomedov

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Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells by Agata Tarczykowska, Per Malmberg, Nathalie Scheers

“…In later years, uptake of iron from complex sources, such as nanoparticles, has been found to be mediated through endocytosis. …”
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Optimizing Hydrogen Production in the Co-Gasification Process: Comparison of Explainable Regression Models Using Shapley Additive Explanations by Thavavel Vaiyapuri

“…However, optimizing this complex process to maximize hydrogen yield remains challenging, particularly when balancing diverse feedstocks and improving process efficiency. …”
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Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V-ATPase by Howard M. Johnson, Ezra Noon-Song, Chulbul M. Ahmed

“…Furthermore, activated JAKs and STATs appear to function coordinately for specific gene activation. These complex events have not been addressed in canonical STAT signaling. …”
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Design of generic vedic ALU using reversible logic by Kanchan S. Tiwari

“…Furthermore, the FPGA-based implementation showcases the scalability of the design for higher bit-width ALUs, highlighting its potential for integration into complex digital systems. The proposed Generic low-power Vedic ALU using reversible logic opens up new opportunities for energy-efficient computing applications, such as portable devices, embedded systems, and Internet of Things (IoT) devices. …”
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PATHOPHYSIOLOGIC MECHANISMS OF THE INFLUENCE OF TISSUE RESPIRATION ENZYMES ON THE MITOCHONDRIAL FUNCTION IN PATIENTS WITH CHRONIC HEPATITIS C by I.Y. Bagmut, S.M. Gramatiuk

“…The mechanism by which enzymes for energy metabolism suppress the replication of the hepatitis C virus is not yet clear, but it probably includes calcium and dissociation of the mammalian replication complex. A detailed understanding of the mechanism by which energy enzymes suppress the replication of HCV infection require additional research.…”
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FACTORS ASSOCIATED WITH DEPRESSION AMONG ADOLESCENTS, ENROLLED IN EDUCATIONAL SETTINGS (AGE 15-19 YEARS) FROM A LOCALITY OF KARACHI, PAKISTAN by Maria Kanwal, Raja Khetpal, Ramna Shafique, Saleha Haider, Perah Ali, Rafay Shahab Ansari

“…Additionally, social media usage showed a complex relationship with depression, 4 hours of use with 60.6% and up to 6 or more hours of use with 60.4% prevalence; and the excessive comparisons with online influencers correlating with higher depression risk, 68.4%. 65% (26 out of 40) of those students who found their parents to be Authoritarian; and those perceiving presence of gender differences applied within their household, 12.0% (81.1% within the variable) (p=0.000), were also associated with depression. …”
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The impact of weather factors on operation of radiation heating system by V. I. Karagusov, I. S. Kolpakov

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A Change in the Classical Order of Setting of Porous Metal Augments with Locked Cups in Hip Revision Surgery: Technical Note and Case Report by Antonio Murcia-Asensio, Francisco Ferrero-Manzanal, Pablo Sanz-Ruiz, Hermenegildo Cañada-Oya, Raquel Lax-Pérez, Christian Goetze

“…Reconstruction of acetabular bone defects by the combination of trabecular metal augments and porous cups can be complex when extensive bone loss and poor-quality bone exists. …”
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Performance assessment of ChatGPT 4, ChatGPT 3.5, Gemini Advanced Pro 1.5 and Bard 2.0 to problem solving in pathology in French language by Georges Tarris, Laurent Martin

“…Conclusion Our study in line with the literature confirms chatbot's moderate performance for questions requiring complex reasoning, with ChatGPT outperforming Google chatbots. …”
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Sheikh al-Qaraḍāwī’s Independent Reasoning (Ijtihād) in Reformulating Contemporary Islamic Criminal Jurisprudence within the Framework of the Modern State by Gaber Mohamed

“…Al-Qaraḍāwī’s views covered a range of complex criminal issues, including his stance on abolishing the death penalty, gender equality in matters of blood money, retribution between Muslims and non-Muslims, the changing jurisprudential concept of guardianship in retribution cases, the minimum threshold for amputation on theft, criticism of the modern prison system, punishment by stoning, the crime of apostasy, and his critique of the prevailing European narrative on corporal punishments in Islam. …”
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Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature. by Adriano Casulli, Stefania Pane, Franco Randi, Paola Scaramozzino, Andrea Carvelli, Carlo Efisio Marras, Andrea Carai, Azzurra Santoro, Federica Santolamazza, Francesca Tamarozzi, Lorenza Putignani

“…<h4>Background</h4>Human cystic echinococcosis (CE) is a zoonotic parasitic infection caused by the larval stage of the species belonging to the Echinococcus granulosus sensu lato (s.l.) complex. Parasitic cysts causing human CE are mainly localized in the liver and in the lungs. …”
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Crayfish optimization based pixel selection using block scrambling based encryption for secure cloud computing environment by Vikas K. Soman, V. Natarajan

“…Traditional encryption algorithms are often inadequate in protecting confidential data, especially digital images, from complex cyberattacks. The increasing reliance on cloud storage and transmission of digital images has made it essential to develop strong security measures to stop unauthorized access and guarantee the integrity of sensitive information. …”
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