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Manipulation of the Complement System for Benefit in Sepsis
Published 2012-01-01“…There is evidence in sepsis, both in rodents and in humans, that activation of the complement system results in excessive production of C5a, which triggers a series of events leading to septic shock, multiorgan failure, and lethality. …”
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In-vitro activation of complement system by lactic acidosis in newborn and adults
Published 2001-01-01Get full text
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Importance of complement system components in ovarian endometriomas. A comparative cohort study
Published 2024-12-01Subjects: Get full text
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients
Published 2025-01-01Subjects: Get full text
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A novel anti-inflammatory activity of lysozyme: modulation of serum complement activation
Published 1998-01-01Subjects: Get full text
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Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective
Published 2025-01-01Subjects: Get full text
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Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy
Published 2025-02-01Subjects: Get full text
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Bothrops asper snake venom and its metalloproteinase BaP–1 activate the complement system. Role in leucocyte recruitment
Published 2000-01-01“…These data show the role of the complement system in bothropic envenomation and the participation of metalloproteinase in the effect. …”
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The role of complement in tumor immune tolerance and drug resistance: a double-edged sword
Published 2025-01-01Subjects: “…complement system…”
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Inhibitors of Complement Activity in Human Breast-Milk: A Proposed Hypothesis of Their Physiological Significance
Published 1999-01-01Subjects: Get full text
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in vitro activation of complement and contact system by lactic acidosis
Published 1998-01-01Subjects: Get full text
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Exploring Potential Complement Modulation Strategies for Ischemia–Reperfusion Injury in Kidney Transplantation
Published 2025-01-01Subjects: Get full text
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Role of Complement in Multiorgan Failure
Published 2012-01-01“…The underlying immune response is highly complex and involves activation of the complement system as a crucial entity of innate immunity. …”
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Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin
Published 2017-01-01“…These findings support the hypothesis of a significant role of MBL and the complement system in the pathophysiology of diabetic nephropathy.…”
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Terminal Complement Pathway Deficiency in an Adult Patient with Meningococcal Sepsis
Published 2022-01-01“…The complement system is an essential part of our innate immune system. …”
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C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation
Published 2025-01-01“…Abstract Background Preeclampsia, characterized by hypertension and proteinuria during pregnancy, poses significant risks to both mother and fetus. The complement system’s aberrant activation, notably the C3AR1, is important to the pathogenesis of preeclampsia, although the precise mechanisms are not fully understood. …”
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Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice
Published 2019-01-01“…The innate immune response against Leptospira is mainly dependent on phagocytosis and activation of the Complement System. In this context, cytokines may drive the early control of infection and the adaptive response. …”
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Innate Immunity and Neuroinflammation
Published 2013-01-01“…Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. …”
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