mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

“…Our findings serve as a focal point for developing a potential mRNA vaccine against K. pneumoniae, indicating the potential of mRNA vaccines for improving next-generation bacterial vaccine.IMPORTANCEK. pneumoniae is a notorious and clinical bacterium that is evolving in community-acquired and nosocomial settings. This opportunistic pathogen causes severe infectious diseases, including urinary tract infection and pneumonia, and causes a concerning global public burden. …”
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Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa by J-D K Lotz, J Porter, H Conradie, T Boyles, B Gaunt, S Dimanda, D Cort

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Évaluation de la prescription et de l’utilisation des benzodiazépines dans la ville de Sidi Bel-Abbès by Derouicha Matmour, Mounia Medjeber, Yassine Merad

“…Methods-: This was a descriptive cross-sectional study carried out from February 01st, 2018 to June 30th, 2018 evaluating the prescription and use of BZDs in of Sidi Bel-Abbès by means of a questionnaire distributed to patients from the psychiatric hospital, the CHU psychiatry department and community pharmacists. The primary endpoint was the assessment of the prescription and use of BZDs in this city. …”
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Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) by Robert Chen, Angus G K McNair, Vafa Rahimi-Movaghar, Julio C Furlan, Benjamin M Davies, Oliver D Mowforth, Iwan Sadler, Bizhan Aarabi, Brian K Kwon, Michael G Fehlings, James S Harrop, Armin Curt, Ellen Sarewitz, Carl Moritz Zipser, Timothy F Boerger, Mark R N Kotter, James Milligan, Lindsay Tetreault, Danyal Khan, Keng Siang Lee, Alvaro Yanez Touzet, Ricardo Rodrigues-Pinto, James D Guest, Sukhvinder Kalsi-Ryan, Shirley Widdop

“…Dissemination strategies will include peer-reviewed scientific publications; conference presentations; podcasts; the identification of AO Spine RECODE-DCM ambassadors; and engagement with relevant journals, funders and the DCM community.…”
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CAMELS-IND: hydrometeorological time series and catchment attributes for 228 catchments in Peninsular India by N. K. Mangukiya, K. B. Kumar, P. Dey, S. Sharma, V. Bejagam, P. P. Mujumdar, P. P. Mujumdar, A. Sharma, A. Sharma

“…We envision that CAMELS-IND will provide a strong foundation for a community-led effort toward gaining new hydrological insights from hydrologically distinct Indian catchments and solving pertinent issues related to water management, quantification and risk assessment of hydrologic extremes, unraveling regional-scale hydrologic functioning, and climate change impact assessment of catchments across India. …”
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Immune responses in children with secondary infection of mycoplasma pneumoniae after COVID-19: focus on eosinophils and IgE by Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang

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Abnormality in optimal forest management by indigenous people in deforestation by A. Mutolib, Y. Yonariza, A. Rahmat

“…In customary law, the production forest is owned by four indigenous communities from the Nagari (villages): Bonjol, Abai Siat Nagari Sikabau, and Sungai Dareh. …”
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Study protocol: type II hybrid effectiveness-implementation study of routine functional status screening in VA primary care by Francesca M. Nicosia, Kara Zamora, LauraEllen Ashcraft, Gregory Krautner, Marybeth Groot, Bruce Kinosian, Cathy C. Schubert, Sumedha Chhatre, Helene Moriarty, Orna Intrator, Andrea Wershof Schwartz, Ariela R. Orkaby, Jason Prigge, Rebecca T. Brown

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Sistem Informasi Geografis Penyebaran Usaha Mikro Kecil Menengah (UMKM) di Kabupaten Majalengka by Muhammad Darul Husni Santoso, Ikbal Jamaludin, Evi Dewi Sri Mulyani

“…With the development of Micro, Small and Medium Enterprises (MSMEs) in Majalengka Regency, it can move the community's economy, especially in the lower sector, namely for micro small and medium businesses. …”
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Study on factors influencing the transport and transformation of polycyclic aromatic hydrocarbons in soil–groundwater systems by Wenxiang Hu, Jie Zhang, Dan Li, Ying Yuan, Ying Tang, Kunlong Hui, Yu Jiang, Wenbing Tan

“…The migration and transformation of PAHs are mainly regulated by organic matter, soil depth, surface water, and microbial community. Soil organic matter fixes PAHs through adsorption sites and active functional groups (including carbonyl and carboxyl groups), while microbial communities mineralize PAHs into H2O, CO2 (aerobic), and CH4 (anaerobic) through metabolic pathways, such as oxygenase, dehydrogenase, and lignin decomposer. …”
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A Phase I/II Study of Ultra-Hypofractionated Carbon-ion Radiation therapy for Low- and Intermediate-Risk Localized Prostate Cancer by Noriyuki Okonogi, MD, PhD, Hiroshi Tsuji, MD, PhD, Kana Kobayashi, MD, PhD, Mio Nakajima, MD, PhD, Shuri Aoki, MD, PhD, Takanobu Utsumi, MD, PhD, Hiroyoshi Suzuki, MD, PhD, Koichiro Akakura, MD, PhD, Tomohiko Ichikawa, MD, PhD, Hitoshi Ishikawa, MD, PhD

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La question du logement social à New York by Catherine Pouzoulet

“…Ultimately, the utopian vision of modern, decent housing for all as well as the concern for community building were defeated by the political and economic forces who favored the building of high‑density, high‑rise, low‑cost public projects. …”
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Improving the provision of clinical pharmacy services in low- and middle-income countries: a qualitative study in tertiary health facilities in Tanzania by Fredrick Kalokola, Dorkasi L Mwakawanga, Ritah F Mutagonda, Hamu J Mlyuka, Wigilya P Mikomangwa, Manase Kilonzi, Wema A Kibanga, Alphonce Ignace Marealle, Bertha Mallya, Deogratias Katabalo, Sofia Sanga, John Rwegasha, Rose Magambo, John Mmassy, Sungwa Kabissi, Josephine A Balati, Peter Maduki, Omary Mashiku Minzi, Appolinary A R Kamuhabwa

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Feasibility and usefulness of Gini coefficients of primary care visits as a measure of service inequality: preliminary findings from a cross-sectional study using region-wide elect... by Xin Yang, Jing Chai, Jing Cheng, DeBin Wang, XingRong Shen, Rong Liu, ManMan Lu, Jia Xu, Ningjing Yang, Guocheng Li

“…The multivariate modelling revealed statistically significant associations between the all-cause-GPV and 10 out of 14 commonly available community-level variables studied.Conclusions GPVs can be accurately estimated using a limited number of months of EMRs and, guided by the relevant framework, analysis of GPVs can unveil useful clues in addressing unequal primary healthcare utilisation.…”
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Risk and Prognosis of Hepatocellular Carcinoma in Mexican Americans with Type 2 Diabetes Mellitus by Hatia RI, Hwang LY, Li R, Troisi C, Jalal PK, Amos CI, Gomez HF, Chun YS, Rashid A, Kaseb AO, Scheet PA, Hassan MM

“…Rikita I Hatia,1 Lu-Yu Hwang,2 Ruosha Li,3 Catherine Troisi,4 Prasun K Jalal,5 Christopher I Amos,6 Henry F Gomez,1 Yun Shin Chun,7 Asif Rashid,8 Ahmed O Kaseb,9 Paul A Scheet,1 Manal M Hassan1 1Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA; 3Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA; 4Department of Management, Policy & Community Health, School of Public Health, The University of Health Science Center at Houston, Houston, TX, USA; 5Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX, USA; 6Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA; 7Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 8Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 9Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Manal M Hassan, Department of Epidemiology, Unit 735, The University of Texas MD Anderson Cancer Center, 6900 Fannin Street, Houston, TX, 77030, USA, Tel +1-713-794-5452, Email mhassan@mdanderson.org Lu-Yu Hwang, Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, 1200 Pressler Street, RAS E717, Houston, TX, 77030, USA, Tel +1-713-500-9384, Email lu-yu.hwang@uth.tmc.eduIntroduction: Hepatocellular carcinoma (HCC) disproportionately affects Hispanic persons with higher age-specific incidence and increased mortality rates compared to non-Hispanic Whites. …”
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Penerapan Metode Weighted Product (WP) Dalam Sistem Pendukung Keputusan Penerimaan Karyawan Pada Dewata Store Fakfak by Nelson Rumui, Nur Sakinah, Cahya Nur Rolan Niah, Fathurrahman Rumalutur

“…Dewata Store Fakfak is a trading company that serves sales and purchases of various community needs. However, recruitment of Dewata Store Fakfak employees is still done manually where applicants still bring files directly and the company often has difficulties because of the large number of prospective employees so the recruitment process still takes a long time. …”
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DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

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The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single‐centre prospective observational cohort study protocol by Bruno Bernardini, Federico Piccioni, Manuele Pastore, Paolo Casale, NicolòMaria Buffi, Giovanni Lughezzani, Massimo Lazzeri, Alberto Saita, Maria Vittoria Fantacci, Stefano Mancon, Filipo Dagnino, Roberto Contieri, Pietro Brin, Stefano Mancin, Andrea Gobbo, Maria Rosaria Martucci, Giovanna Cerina, Sara Ghirmai, Ezio Lanza, Giulia Goretti, Giorgio Ferruccio Guazzoni, Rodolfoi Hurle

“…The pathway involves the patient, family members and community services.…”
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Reflections and trajectories for interdisciplinary research on the energy transition by Cesare Sposito, Francesca Scalisi

“…From the published contributions, it emerges the need for a paradigm shift that, on the one hand, is characterised by a ‘sufficiency’ approach (regarding new land occupation and new constructions) and a circular economy (to limit the use of non-renewable resources) capable of exploiting the potential of technologies for the new services made possible by digitisation, and on the other hand, relies on new user awareness of the limits of the Planet, pursuable through ‘soft’ urgent actions that are robust, flexible and easy to implement as they require a lower financial commitment. We assume that community energy renewable energy production from hydrogen and production chains can help mitigate greenhouse gas emissions. …”
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Evaluation of parent and youth experiences in advisory groups as part of a mental healthcare clinical trial: protocol for a mixed-method study by Maria-Jose Santana, Gina Dimitropoulos, Suneeta Monga, Isabelle J Gagnon, Bruce Wright, Jananee Rasiah, Katrina Hurley, Antonia Stang, Amanda Newton, Stephen Freedman, Jennifer Thull-Freedman, Kassi Prisnie, Yazid N Al Hamarneh, Ellen Louise Lipman, Yaron Finkelstein, Robert Porter, Mohamed Eltorki, Lee Macdonald, Gareth Hopkin, Matthew Prebeg, Margaret Steele, Ahmed Mater, Laurence Katz, Brian Greenfield, Laurie Plotnick

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