The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows by Zheng Zhou, Kang Yong, Zhengzhong Luo, Zhenlong Du, Tao Zhou, Xiaoping Li, Xueping Yao, Liuhong Shen, Shumin Yu, Yixin Huang, Suizhong Cao

“…Analysis of the microbiota community showed that DBT modulated the composition and structure of the hindgut microbiota. …”
Get full text

Epigenome-wide DNA methylation profiling in septic and non-septic patients with similar infections: potential use as sepsis biomarkers by Ian López-Cruz, Ian López-Cruz, José Luis García-Giménez, José Luis García-Giménez, José Luis García-Giménez, Manuel Madrazo, Manuel Madrazo, Judit García-Guallarte, Laura Piles, Federico V. Pallardó, Federico V. Pallardó, Federico V. Pallardó, Arturo Artero, Arturo Artero

“…This study explores the role of DNA methylation in white blood cells in sepsis pathogenesis.MethodsA prospective case-control study was conducted to compare DNA methylation profiles between patients with community-acquired sepsis and matched controls who had similar infections but did not develop sepsis. …”
Get full text

Exploring under-five child malnutrition in Bangladesh: Analysis using the Extended Composite Index of Anthropometric Failure (ECIEF) by Farzana Akhter Bornee, Mohammad Rocky Khan Chowdhury, Badrun Naher Siddique, Baki Billah, Farjana Akter, Md Nazmul Karim

“…Mothers with no formal education (Adjusted odds ratio (AOR): 1.51, 95% CI: 1.08, 2.10), underweight mother (AOR: 1.54, 95% CI: 1.03, 1.83), poorest socio-economic status (AOR: 2.14, 95% CI: 1.64, 2.81), children age 24-35 months of age (AOR: 2.37, 95% CI: 1.97, 2.85), and fourth and above birth order children (AOR: 1.41, 95% CI: 1.16, 1.72) were identified key factors associated with childhood malnutrition while adjusting community and household level variations. Conclusion: In Bangladesh, two out of five children were malnourished and one in 35 children was overweight. …”
Get full text

IgG Glycosylation Profile and the Glycan Score Are Associated with Type 2 Diabetes in Independent Chinese Populations: A Case-Control Study by Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo

“…Findings were validated in the replication population from Beijing Xuanwu community cohort (280 cases and 508 controls). Area under curve (AUC) using 10-fold and bootstrap validation, net reclassification index (NRI), and integrated discrimination index (IDI) were calculated for the glycan score. …”
Get full text

Resident-based learning model for sustainable resident participation in municipal solid waste management program by A. Ghazali, J. Tjakraatmadja, . Sunarti, E.Y.D. Pratiwi

“…Therefore, this study aimed to develop a resident-based learning model to encourage sustainable resident participation in waste management programs at the household level using the Community of Practice approach.  METHODS: This study was a conceptual model study using a case study as the research strategy. …”
Get full text

Associations between neutrophil-percentage-to-albumin ratio level and all-cause mortality and cardiovascular disease-cause mortality in diabetes population by Geng Shen, Yuting Liu, Can Zhou, Wei Luo, Yun-xiao Yang, Shuai Guo, Jiayi Yi, Lin Wang, Wei Li, Zhao-gong Zhi, Xiu-huan Chen, Chen Li, Yanyan Jin, Hai Gao

“…This study aimed to investigate the association between neutrophil percentage-to-albumin ratio (NPAR) with all-cause mortality and the risk of cardiovascular disease (CVD) mortality in community-dwelling individuals with T2DM. Methods This prospective cohort study included 3602 adults aged 20 or above who were diagnosed with diabetes by the American Diabetes Association criteria in the US National Health and Nutrition Examination Survey (NHANES) database from 1999 to 2016, and followed up until 2019. …”
Get full text

Alterations in fecal bacteriome virome interplay and microbiota-derived dysfunction in patients with schizophrenia by Shiwan Tao, Yulu Wu, Liling Xiao, Yunqi Huang, Han Wang, Yiguo Tang, Siyi Liu, Yunjia Liu, Qianshu Ma, Yubing Yin, Minhan Dai, Min Xie, Jia Cai, Zhengyang Zhao, Qiuyue Lv, Jiashuo Zhang, Mengting Zhang, Menghan Wei, Yang Chen, Mingli Li, Qiang Wang

“…We compared the gut bacterial community composition and specific abundant bacteria in SCZ patients and HCs. …”
Get full text

A cross-sectional study exploring the predictors of herpes zoster vaccination for people aged over 50 years old in Chaoyang district, Beijing by Jiao Zhang, Shuo Zhang, Bin Jia, Yunhua Bai, Zhen Li, Fang Liu, Yingxue Hu, Xiaojing Guo, Jianxin Ma, Shuming Li, Qian Shi

“…It is recommended to enhance the role of medical staff in advocating for vaccination, conduct community-based educational initiatives that focus on varicella, herpes zoster, and related knowledge, and alleviate the financial burden to improve the herpes zoster vaccination coverage.…”
Get full text

Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments by Ning Ning, Sunandana Chandra, Andriy Moshyk, Divya Patel, Isabella C Glitza Oliva, Jennell Palaia, Leon A Sakkal, Natalia Han, Shardul Odak, Jordana K Schmier

“…Objective This study examined real-world treatment patterns and outcomes in patients with melanoma brain metastasis (MBM) treated with first-line immunotherapy consisting of nivolumab plus ipilimumab or anti-programmed death-1 (PD-1) monotherapy (nivolumab or pembrolizumab) or targeted therapy consisting of BRAF/MEK inhibitors.Design Retrospective chart review study.Setting Academic medical centres, community hospitals and private practice offices.Participants Included patients diagnosed with melanoma with brain metastasis in the USA.Outcome measures The statistical analysis was descriptive in nature. …”
Get full text

How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh? by Ariful Khan, Md Rezaul Karim, Mohammed A.S. Arfin-Khan, Md. Shamim Reza Saimun, Fahmida Sultana, Sharif A. Mukul

“…We observed that the community-weighted mean (CWM) leaf trait values were predominantly higher in the southwestern regions of KNP, while in RKWS, they were primarily distributed in the northern or southern regions. …”
Get full text

The Prevalence of Dermoscopy Use Among Dermatology Residents in Riyadh, Saudi Arabia: Cross-Sectional Study by Abdullah Almeziny, Rahaf Almutairi, Amal Altamimi, Khloud Alshehri, Latifah Almehaideb, Asem Shadid, Mohammed Al Mashali

“…However, the overall extent of dermoscopy use within the dermatology community remains unclear, highlighting the need for further education. …”
Get full text

International REACH forgiveness intervention: a multisite randomised controlled trial by Tyler J Vanderweele, Nicole Rodriguez, Richard G Cowden, Man Yee Ho, Everett L Worthington, Andrea Ortega Bechara, Zhuo Job Chen, Elly Yuliandari Gunatirin, Shaun Joynt, Viacheslav V Khalanskyi, Hennadii Korzhov, Ni Made Taganing Kurniati, Anastasiya Anastasiya Salnykova, Liudmyla Shtanko, Sergiy Tymchenko, Vitaliy L Voytenko, Anita Zulkaida, Maya B Mathur

“…Final follow-up occurred on 25 October 2021.Setting Participants were recruited from community-based samples in sites in Colombia, Hong Kong, Indonesia, South Africa, and Ukraine.Participants Individuals (n=7837) were screened for eligibility. …”
Get full text

A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Nurses and midwives are essential to a holistic approach to AMR stewardship (AMS) and IPC within LMICs.Objective(1) Adapt AMS and IPC training programs and practice guidelines for community- and hospital-based nurses and midwives in Nepal; (2) pilot and conduct training outcome and process evaluations.DesignA one-day training was developed through partnerships between Henry Ford Health and nursing and midwifery organizations and teaching facilities in Nepal. …”
Get full text

Designing and Modeling Digital Transformation in the Automotive Industry: Leveraging the Fourth Industrial Revolution by Mohammad Saeed Mozafari Mehr, Mohammad Taghi Taghavifard

“…Methods This study adopts an applied-developmental approach in terms of its purpose, utilizes a descriptive survey method for data collection, and employs a mixed data analysis method. The community of participants in the qualitative section comprised of experts, policymakers, academics, managers of knowledge-based companies, and senior managers of Iran Khodro Company. …”
Get full text

The Linda Kizazi study: a comparison of morbidity and mortality from birth to 2 years between children who are HIV-unexposed and HIV-exposed, uninfected in the era of universal ant... by John Kinuthia, Dara A Lehman, Dalton Wamalwa, Brenda Wandika, Emily R Begnel, Ednah Ojee, Judy Adhiambo, Eliza Mabele, Vincent Ogweno, Efrem S Lim, Soren Gantt, Jennifer Slyker

“…To assess whether this difference persists in the era of universal antiretroviral therapy (ART), we conducted a cohort study to compare the risk of acute diarrhoea, respiratory tract infections (RTI), malaria, hospitalisation, and all-cause mortality between Kenyan CHEU and CHUU from birth to 2 years.Methods From December 2018 to March 2020 at Mathare North Health Centre in Nairobi, we recruited pregnant women living with HIV on ART for ≥6 months and pregnant women without HIV from the same community. We followed the mother–infant pairs for 2 years post partum and collected data on symptoms of illness, clinical visits and diagnoses, and infant feeding every 3 months; a self-selected subset of participants also received weekly data collection for up to 1 year. …”
Get full text

Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C. by Abhishek Bhatia, Alexander J Preiss, Xuya Xiao, M Daniel Brannock, G Caleb Alexander, Robert F Chew, Hannah Davis, Megan Fitzgerald, Elaine Hill, Elizabeth P Kelly, Hemalkumar B Mehta, Charisse Madlock-Brown, Kenneth J Wilkins, Christopher G Chute, Melissa Haendel, Richard Moffitt, Emily R Pfaff, N3C Consortium

“…We observed disparities in Paxlovid treatment, with lower rates among black and Hispanic or Latino patients, and within socially vulnerable communities. This study's main limitation is that it estimates causal effects using observational data and could be biased by unmeasured confounding.…”
Get full text

Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania. by Geofrey Makenga, Vito Baraka, Filbert Francis, Daniel T R Minja, Samwel Gesase, Edna Kyaruzi, George Mtove, Swabra Nakato, Rashid Madebe, Sif R Søeborg, Kathrine H Langhoff, Helle S Hansson, Michael Alifrangis, John P A Lusingu, Jean-Pierre Van Geertruyden

“…Given malaria infection in schoolchildren is mostly asymptomatic; an addition of interventional programmes such as intermittent preventive treatment of malaria in schoolchildren (IPTsc) would probably act as a potential solution while calling for an improvement in the current tools such as bednet use, school food programme, and community-based (customised) health education with an emphasis on nutrition and malaria control.…”
Get full text

Genomic Characterization of Carbapenemase-Producing Enterobacteriaceae from Clinical and Epidemiological Human Samples by Alexander Tristancho-Baró, Laura Eva Franco-Fobe, Monica Pilar Ariza, Ana Milagro, Ana Isabel López-Calleja, Blanca Fortuño, Concepción López, Miriam Latorre-Millán, Laura Clusa, Rosa Martínez, Carmen Torres, Antonio Rezusta

“…Advanced genomic tools enhance the detection of resistance genes, virulence factors, and high-risk clones, thus improving the management of MDR infections. In the Autonomous Community of Aragon, the diversity and incidence of carbapenemase-producing Enterobacteriaceae (CPE) have increased during the last years. …”
Get full text

Gender and ethnoracial disparities in Veterans’ trauma exposure prevalence across differing life phases by Fernanda S. Rossi, Yael I. Nillni, Alexandria N. Miller, Annie B. Fox, Johanne Eliacin, Paula P. Schnurr, Christopher C. Duke, Jaimie L. Gradus, Tara E. Galovski

“…., sexual assault, physical assault, community violence, captivity, serious accident, witnessing violent death) at each wave of data collection using items from a modified Life Events Checklist. …”
Get full text

One-pot green synthesis of BSA-capped O-CQDs as an effective fluorescent sensing platform for sensitive and selective detection of promethazine drug by S. Viji, A. Dinesh, K. Radhakrishnan, L. Srimathi Priya, C. Sivasankari, Madhappan Santhamoorthy, Manikandan Ayyar, V. Mohanavel, Mohamed Hashem, Hassan Fouad, G. Ramachandran, S. Santhoshkumar

Get full text