Completion of the Central Italy daily precipitation instrumental data series from 1951 to 2019 by Gamal AbdElNasser Allam Abouzied, Guoqiang Tang, Simon Michael Papalexiou, Martyn P. Clark, Eleonora Aruffo, Piero Di Carlo

“…To address this, gap filling is commonly used to produce complete hydrometeorological data series without missing values. …”
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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…Six categories of barriers and enablers were identified, which include (1) political, social and culture factors, (2) institutional environment and resources factors, (3) guideline itself related factors, (4) healthcare provider-related factors, (5) patient-related factors and (6) behavioural regulation-related factors. The most commonly reported barriers within the above-mentioned categories were suboptimal healthcare networks and interprofessional communication pathways, time constraints, poor applicability of CPGs in real-world practice, lack of knowledge and skills, poor motivations and adherence, and inadequate reinforcement (eg, remuneration). …”
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Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p by Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu

“…Sepsis-induced acute lung injury is a common critical illness in intensive care units with no effective treatment is currently available. …”
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Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (N = 19) by Carlijn de Roos, Julia Offermans, Samantha Bouwmeester, Ramón Lindauer, Frederike Scheper

“…Background: Trauma exposure is common in (pre) school-aged children and around one-fifth of exposed children meet the criteria for post-traumatic stress disorder (PTSD). …”
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Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

“…IntroductionUndernutrition risk in adults is a common but undiagnosed condition, while obesity is highly prevalent in this population. …”
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Cinnamic Acid Compounds (<i>p</i>-Coumaric, Ferulic, and <i>p</i>-Methoxycinnamic Acid) as Effective Antibacterial Agents Against Colistin-Resistant <i>Acinetobacter baumannii</i> by Alaaddin Korkut, Serap Özkaya Gül, Esra Aydemir, Hakan Er, Elif Odabaş Köse

“…Colistin-resistant <i>Acinetobacter baumannii</i> (COLR-Ab) is an opportunistic pathogen commonly associated with nosocomial infections, and it is difficult to treat with current antibiotics. …”
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Powdery mildew resistance of apple clonal rootstocks from the collection of the Michurinsk State Agrarian University by I. N. Shamshin, M. L. Dubrovsky, A. A. Trifonova, K. V. Boris, A. M. Kudryavtsev

“…The Pl-d and Pl-1 genes identified in 33 (41.25 %) and 31 (38.75 %) accessions, respectively, were the most common in the collection. The Pl-w gene was detected only in two accessions. …”
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Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A^y) mutation by E. N. Makarova, T. V. Yakovleva, N. Yu. Balyibina, K. O. Baranov, E. I. Denisova, A. D. Dubinina, N. A. Feofanova, N. M. Bazhan

“…Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects on melanocortin obesity are unknown. …”
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Phytophthora: an ancient, historic, biologically and structurally cohesive and evolutionarily successful generic concept in need of preservation by Clive Brasier, Bruno Scanu, David Cooke, Thomas Jung

“…The long phylogenetic branches of the DMs indicate this occurred rather rapidly, via paraphyletic evolutionary ‘jumps’. Such paraphyly is common in successful organisms. The proposal to divide Phytophthora appears more a device to address the issue of the convergent evolution of the DMs than the structure of Phytophthora per se. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

“…Background Silver diamine fluoride (SDF) is recognized for its potent antibacterial properties and is commonly used in dentistry to treat carious lesions. …”
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An Efficient 3D Convolutional Neural Network for Dose Prediction in Cancer Radiotherapy from CT Images by Lam Thanh Hien, Pham Trung Hieu, Do Nang Toan

“…<b>Introduction</b>: Cancer is a highly lethal disease with a significantly high mortality rate. One of the most commonly used methods for treatment is radiation therapy. …”
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Immune checkpoint inhibitors in cancer patients with autoimmune disease: Safety and efficacy by Jiayuan Le, Yuming Sun, Guangtong Deng, Yating Dian, Yanli Xie, Furong Zeng

“…During ICIs treatment, irAEs are common among cancer patients with autoimmune diseases, but severe irAEs is relatively low. …”
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Chlamydia cases in women of reproductive age, 2006–2020: an analysis of surveillance data from Southern China by Peizhen Zhao, Peng Liang, Jinshen Wang, Wenqian Xu, Shujie Huang, Cheng Wang

“…Abstract Background Chlamydia is common among women of reproductive age and can cause serious health issues. …”
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Effect of Proparacaine 0.375%-Sodium Fluorescein 0.25% Eye Drop Mixture and Fluorescein Strip on Anterior Segment Parameters by Mustafa Doğan, Mehmet Cem Sabaner, Mehmet Akif Erol

“…To determine the effect of proparacaine 0.375%-sodium fluorescein 0.25% eye drop mixture and fluorescein strip on anterior segment parameters commonly used in routine ophthalmology practice. Methods. 115 healthy volunteers without any systemic or ocular disease were divided into two groups. 57 volunteers were in the proparacaine 0.375%-sodium fluorescein 0.25% eye drop mixture group, and 58 volunteers were in the fluorescein strip group. …”
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Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021 by Yanyu Zhang, Quanxin Su, Jiawen Yu, Xiuli Sun

“…PurposeMultiple myeloma (MM) is a hematologic malignancy originating from plasma cells with clinical manifestations such as hypercalcemia, cytopenias (most commonly anemia) and renal failure. Here, we analyzed the disease burden and changing trends of MM in China from 1990 to 2021, aiming to provide a scientific and effective basis for the prevention and control of MM disease in China.MethodsWe extracted MM related data from the Global Burden of Diseases (GBD) 2021 database from 1990 to 2021. …”
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Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking by Charlotte Waddell, Christine Schwartz, Jenny Lou Barican, Donna Yung, Yufei Zheng, Katholiki Georgiades

“…Anxiety (5.2%), attention-deficit/hyperactivity (3.7%), oppositional defiant (3.3%), substance use (2.3%), conduct (1.3%) and depressive (1.3%) disorders were the most common. Among children with mental disorders, only 44.2% (95% CI 37.6% to 50.9%) received any services for these conditions.Conclusions An estimated one in eight children have mental disorders at any given time, causing symptoms and impairment, therefore requiring treatment. …”
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The Systemic Effects of Blood Flow Restriction Training: A Systematic Review by Bradley C Miller, Alexander W Tirko, Justin M Shipe, Olivia R Sumeriski, Kelley Moran

“…PEDro scores ranged between 4 and 8, and had CEBM levels of evidence of 1 and 2. Common systems studied included cardiovascular, musculoskeletal, endocrine, and psychosocial. …”
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The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

“…Aim In this study, we analyzed expression profile datasets and miRNA expression profiles related to HCC from the GEO using R software to detect differentially expressed genes (DEGs) and differentially expressed miRNAs (DEmiRs). Methods and results Common DEGs were identified, and a PPI network was constructed using the STRING database and Cytoscape software to identify hub genes. …”
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Risk of pneumonia in patients with isolated minor rib fractures: a nationwide cohort study by Yu-Hsun Wang, Ming-Chih Chou, Sai-Wai Ho, Ying-Hock Teng, Shun-Fa Yang, Han-Wei Yeh, Chao-Bin Yeh

“…Objectives Isolated minor rib fractures (IMRFs) after blunt chest traumas are commonly observed in emergency departments. However, the relationship between IMRFs and subsequent pneumonia remains controversial. …”
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Comparison of Transcutaneous Electric Nerve Stimulation (TENS) and Microcurrent Nerve Stimulation (MENS) in the Management of Masticatory Muscle Pain: A Comparative Study by B. Saranya, Junaid Ahmed, Nandita Shenoy, Ravikiran Ongole, Nanditha Sujir, Srikant Natarajan

“…TMD are considered to be the most common orofacial pain conditions of nondental origin. …”
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