Gabapentin versus Transdermal Fentanyl Matrix for the Alleviation of Chronic Neuropathic Pain of Radicular Origin: A Randomized Blind Multicentered Parallel-Group Noninferiority Tr... by Chang Ju Hwang, Jae Hyup Lee, Jung-Hoon Kim, Sang Hyuk Min, Kun-Woo Park, Hyoung-Yeon Seo, Kwang-Sup Song

“…The overall incidence of at least one AE was similar for fentanyl matrix (67.3%) and gabapentin (69.6%). The most commonly reported AEs for patients treated with fentanyl matrix and gabapentin included dizziness (30.8% vs. 44.6%, respectively), somnolence (26.9% vs. 35.7%), and constipation (15.4% vs. 17.9%). …”
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Integration of Umbilical Cord Mesenchymal Stem Cell Application in Hydroxyapatite-Based Scaffolds in the Treatment of Vertebral Bone Defect due to Spondylitis Tuberculosis: A Trans... by Ahmad Jabir Rahyussalim, Ahmad Nugroho, Muhammad Luqman Labib Zufar, Irfan Fathurrahman, Tri Kurniawati

“…Vertebral bone defect represents one of the most commonly found skeletal problems in the spine. Progressive increase of vertebral involvement of skeletal tuberculosis (TB) is reported as the main cause, especially in developed countries. …”
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Development of a marker panel for genotyping of domestic soybean cultivars for genes controlling the duration of vegetation and response to photoperiod by R. N. Perfil’ev, A. B. Shcherban, E. A. Salina

“…The studied cultivars contained the most common alleles of the GmFT2a and GmFT5a genes, with the exception of the ‘Cassidi’ cultivar having a rare dominant allele GmFT5a-H4. …”
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Brodalumab: Six-Year US Pharmacovigilance Report by Mark G. Lebwohl, John Y. Koo, April W. Armstrong, Bruce E. Strober, Soo Han Yoon, Nicole N. Rawnsley, Earl L. Goehring, Gina D. Mangin, Abby A. Jacobson

“…Methods Crude adverse event (AE) reporting rates per 100 patients were calculated for common AEs and AEs of special interest reported to Ortho Dermatologics by US patients and healthcare providers from August 15, 2017 through August 14, 2023. …”
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Do Maternal Vitamin D Levels Influence Vitamin D Levels in Preterm Neonates? by M. Panda, J. McIntosh, T. Chaudhari, A. L. Kent

“…VitD deficiency/insufficiency in mothers of preterm neonates and in preterm neonates at birth is common. Routine screening of maternal VitD and their preterm neonates along with individualized supplementation regimens in mothers and preterm infants may optimize VitD status and reduce risk of ongoing VitD deficiency/insufficiency.…”
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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

“…These results suggest that Perforin-2 is not essential for host defense against fungal infections in otherwise immune-competent mice.IMPORTANCEHumans encounter fungal pathogens daily and rely on innate immune cells to clear Aspergillus fumigatus, the leading cause of mold pneumonia worldwide, and Candida albicans, the most common cause of fungal bloodstream infections. The World Health Organization has classified A. fumigatus and C. albicans as critical priority fungal pathogens due to the emergence of drug resistance and the increasing number of susceptible individuals across the globe. …”
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Detection of Dengue Virus-Specific IgM and IgG Antibodies through Peptide Sequences of Envelope and NS1 Proteins for Serological Identification by Pradeep Kumar Nagar, Deepali Savargaonkar, Anupkumar R. Anvikar

“…On the basis of algorithm prediction from DNASTAR, BCEPRED, and IEDB data resources, twelve peptides of E (EP1 to EP12) and eight peptides of NS1 (NS1-1 to NS1-8) were selected, which were common in all serotypes. Sequence homologies of peptides with other Flavivirus were checked by Multiple Sequence Alignment Tool ClustalX2. …”
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An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit... by Maryam Afzal Dehkordi, Tahmineh Farajkhoda, Mahdi Khanabadi, Farimah Shamsi

“… Background: Sexual performance anxiety is common among infertility treatments. Psychological interventions are options for couples who do not tolerate psychiatric medications or like psychotherapy with pharmacotherapy. …”
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Use of Dietary Supplements among Spanish Pediatricians in Daily Practice: A Cross-Sectional Survey Study by Ignacio Güemes Heras, Alicia Santamaría-Orleans, José F. Colinas Herrero, Pilar Gómez Sorrigueta, Luis Ortiz González, Raquel de la Iglesia-Arnaez, Alejandro Canals Baeza

“…Short duration of treatment (<1 month) was significantly more common in the synbiotics group (90.5%), whereas longer duration of treatment (>3 months) was more frequent in the omega-3 group (79.1%). …”
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Conservation networks do not match the ecological requirements of amphibians by Matutini, Florence, Baudry, Jacques, Fortin, Marie-Josee, Pain, Guillaume, Pithon, Josephine

“…We highlighted a mismatch between the most suitable amphibian habitats at the regional scale and the conservation network, both for common species and for species of high conservation concern. …”
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Simulation of Flow Around a Finite Rectangular Prism: Influence of Mesh, Model, and Subgrid Length Scale by Xutong Zhang, Maxime Savoie, Mark K. Quinn, Ben Parslew, Alistair Revell

“…The shear-layer-adapted (SLA) subgrid length scale (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mo>Δ</mo><mi>SLA</mi></msub></semantics></math></inline-formula>) displayed consistently superior performance compared to the more widely used length scale based on local cell volume, particularly for moderate mesh resolutions commonly employed in industrial settings with limited resources. …”
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THE BIOSYNTHESIS REGULATION OF POTATO STEROIDAL GLYCOALKALOIDS by K. A. Ivanova, S. V. Gerasimova, E. K. Khlestkina

“…However, information about the tissue-specific mechanisms of switching between the pathways of synthesis of SGA and other compounds having common precursors with SGAs can be used to manipulate the tissue-specific level of steroidal glycoalkaloids. …”
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Comparing the effectiveness, safety and tolerability of interventions for depressive symptoms in people with multiple sclerosis: a systematic review and network meta-analysis proto... by Amalia Karahalios, Allan G Kermode, Yvonne C Learmonth, Julia Lyons, Stephanie Campese, Alexandra Metse, Claudia H Marck

“…Background Comorbid depression is prevalent in people with multiple sclerosis (MS). Depression is commonly untreated or undertreated, thus, there is a need for effective and safe interventions and current guidelines recommend psychological and pharmaceutical interventions for people with MS. …”
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Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…Patients on UST had a higher Charlson Comorbidity Index score. Common comorbidities (>10%) included anemia, anxiety, depression, and hypertension. …”
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A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…The median prevalence of PIK3CA mutation was 36% (range: 13.3% to 61.5%); identified testing approaches more commonly used tissue over liquid biopsies and primarily utilized next-generation sequencing (NGS), polymerase chain reaction (PCR), or Sanger sequencing. …”
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Diversity and Conservation Status of Large Mammals in Ghamot National Park, Azad Jammu and Kashmir, Pakistan by Muhammad Jahangeer, Siddique Muhammad, Muhammad Shakeel, Mir Muhammad Saleem, Ali Usman, Hussain Abid

“…Fecal dropping was the most common type of indirect evidence (n=73; 55.72%), followed by foot prints (n=29; 9.94%) and dens/latrine (n=19; 14.50%). …”
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Prevalence of foodborne zoonotic pathogens in milk and milk products along the water buffalo milk value chain in Bangladesh by Shuvo Singha, Gerrit Koop, Md. Mizanur Rahman, Fabrizio Ceciliani, Md. Matiar Rahman Howlader

“…., eae, stx1, and stx2 of which the stx2 genotype was most prevalent and was most common in milk products (74%). The prevalence of L. monocytogenes and Y. enterocolitica were more prevalent on the farms (65 - 79%) than in the later milk value chain nodes. …”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…Patients typically first present their concerns about their cognition to a primary care provider, but in this setting, cognitive impairment is commonly underdiagnosed. There is also high variability in how cognitive evaluations are performed. …”
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Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing by Gulam Altab, Brian J. Merry, Charles W. Beckett, Priyanka Raina, Inês Lopes, Katarzyna Goljanek-Whysall, João Pedro de Magalhães

“…Upregulated genes were commonly involved in protein folding and immune responses; meanwhile, downregulated genes were often related to developmental biology. …”
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Prevalence of Dental Anomalies in Pediatric Patients at King Saud University Dental Hospital, Riyadh, Saudi Arabia—A Radiographic Analysis by Mannaa K. Aldowsari, Ayman M. Sulimany, Abdulmajeed Alkhathlan, Nawaf Alfhaed, Mohammed Aldosari, Saud Alayed, Saad Bin Saleh, Abeer A. Alshami

“…Conclusions: This study showed that hypodontia was the most common dental anomaly, followed by ectopic eruption and taurodontism. …”
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