Systemic Therapy of Neuroendocrine Neoplasia: Single Center Experience from a Cohort of 110 Consecutive Cases by Karin Mayer, Selina Kiry, Anna Yordanova, Hojjat Ahmadzadehfar, Florian C. Gaertner, Ralph A. Bundschuh, Markus Essler, Maria A. Gonzalez-Carmona, Christian P. Strassburg, Hanno Matthaei, Philipp Lingohr, Savita Bisht, Peter Brossart, Georg Feldmann

“…Peptide receptor radionuclide therapy (PRRT) and cytostatic chemotherapy were the second most common options, with PRRT being used more frequently in NET G1 and G2 and chemotherapy in NEC G3. …”
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Air Particle Abrasion in Dentistry: An Overview of Effects on Dentin Adhesion and Bond Strength by Andreea Kui, Smaranda Buduru, Anca Labuneț, Sorina Sava, Dalia Pop, Iris Bara, Marius Negucioiu

“…<b>Background/Objectives:</b> Air particle abrasion (APA) is a common surface preparation method in dentistry, particularly for improving bond strength to dentin. …”
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Association between Clinical Characteristics and Laboratory Findings with Outcome of Hospitalized COVID-19 Patients: A Report from Northeast Iran by Sahar Sobhani, Reihaneh Aryan, Elham Kalantari, Salman Soltani, Nafise Malek, Parisa Pirzadeh, Amir Yarahmadi, Atena Aghaee

“…Male sex, age, hospitalization duration, and admission to ICU were significantly related to mortality rate. Headache was a more common feature in patients who survived (p=0.017). …”
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Phenotypic plasticity vs. local genetic adaptation: essential oil diversity of natural immortelle (Helichrysum italicum (Roth.) G.Don) populations along eastern Adriatic coast by Tonka Ninčević Runjić, Dejan Pljevljakušić, Marko Runjić, Martina Grdiša, Martina Grdiša, Zlatko Šatović, Zlatko Šatović

“…The essential oil of Helichrysum italicum (Roth) G.Don, commonly known as immortelle, is produced in Mediterranean countries to meet the increasing demand of the cosmetic and pharmaceutical industries. …”
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Effect of Root Dentin Pretreatment on Micro-Push-Out Bond Strength of Fiber Posts to Root Canal Dentin: Cold Atmospheric Argon Plasma (CAAP) and Ethylenediaminetetraacetic Acid (ED... by Farzaneh Sadeghi Mahounak, Mahdi Abbasi, Naghmeh Meraji, Maryam Rezazadeh Sefideh, Mohammad Javad Kharrazi Fard, Elham Ahmadi, Ladan Ranjbar Omrani

“…Debonding from the root canal dentin is the most common failure mode of fiber posts. This study aimed to assess the effects of cold atmospheric argon plasma (CAAP) and ethylenediaminetetraacetic acid (EDTA) on micro-push-out bond strength of fiber posts to root canal dentin. …”
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CircRNF13 enhances IGF2BP1 phase separation-mediated ITGB1 mRNA stabilization in an m6A-dependent manner to promote oral cancer cisplatin chemoresistance by Xuemeng Xu, Qiu Peng, Zongyao Ren, Yaqian Han, Xianjie Jiang, Zhu Wu, Shiming Tan, Wenjuan Yang, Linda Oyang, Xia Luo, Jinguan Lin, Longzheng Xia, Mingjing Peng, Nayiyuan Wu, Yanyan Tang, Hao Tian, Yujuan Zhou, Qianjin Liao

“…Abstract Oral cancer ranks among the most common malignancies within the head and neck region; however, its etiology remains inadequately understood despite substantial research advances in recent years. …”
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Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

“…Hair graying is one of the common visible signs of human aging, resulting from decreased or abolished melanogenesis due to the depletion of melanocyte stem cells through excess accumulation of oxidative stress. …”
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Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review by Aleksander Jentkiewicz, Esmail Haj Obeid, Jakub Ulrych, Jan Krupa, Maciej Malinowski, Michał Krasowski, Alicja Kalinowska, Wiktoria Pietras, Adrian Kozieł, Zofia Kurek

“…Clinical trials consistently demonstrate significant weight loss, positive action on cardiovascular risk and better glycemic control. All GLP-1 RAs have common side effects which are gastrointestinal disorders, and gallbladder-related issues, but their safety profiles are acceptable.   …”
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Rap1 and mTOR signaling pathways drive opposing immunotoxic effects of structurally similar aryl-OPFRs, TPHP and TOCP by Bilin Zhao, Shuang Zheng, Gaoxiang Yang, Zhijun He, Jiewei Deng, Lijuan Luo, Xinyan Li, Tiangang Luan

“…Aryl organophosphorus flame retardants (aryl-OPFRs), commonly used product additives with close ties to daily life, have been regrettably characterized by multiple well-defined toxicity risks. …”
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Scaling up of parenting support to prevent violence against children in Tanzania: insights from policymakers and service providers by Sabine van Tuyll van Serooskereken Rakotomalala, Kija Nyalali, Joyce Wamoyi, Onduru Gervas Onduru, Gerry Mshana, F. Marijn Stok, Mara A. Yerkes, John B. F. De Wit

“…Current factors hindering the scale-up include the lack of a common understanding of what evidence-based parenting programmes entail, inadequate provision of human and financial capital to implement the programmes using community resources and deeply engrained social norms around adultism and gender. …”
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Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study by Bruno Fattizzo, Alfredo Marchetti, Alessandro Bosi, Carmelo Gurnari, Juri Alessandro Giannotta, Giacinto Luca Pedone, Elena Rossi, Valentina Carrai, Andrea Guido, Filippo Brioschi, Monica Carpenedo, Monica Crugnola, Domenica Caramazza, Livia Leuzzi, Monia Marchetti, Gabriele Merati, Simona Malato, Fabrizio Vianello, Andrea Patriarca, Hussein Awada, Marta Bortolotti, Marta Canzi, Niccolò Bolli, Marco Capecchi, Frederick Chen, Andrea Artoni, Jaroslaw P. Maciejewski, Wilma Barcellini

“…After exclusion of germ line variants and polymorphisms, 31 of 167 (18.5%) were defined as having clonal hemopoiesis. Most commonly mutated genes were TET2, DNMT3A, SRSF2, and ASXL1 (median variant allele frequency, 29%); 19 of 31 patients (68%) had high-risk variants, and 8 had multiple mutations. …”
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Identification of TMPRSS3 as a Significant Contributor to Autosomal Recessive Hearing Loss in the Chinese Population by Xue Gao, Sha-Sha Huang, Yong-Yi Yuan, Jin-Cao Xu, Ping Gu, Dan Bai, Dong-Yang Kang, Ming-Yu Han, Guo-Jian Wang, Mei-Guang Zhang, Jia Li, Pu Dai

“…To determine whether this mutation arose from a common ancestor, we analyzed six short tandem repeat (STR) markers spanning the TMPRSS3 gene. …”
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Assessment of oat varieties with different levels of breeding refinement from the Vavilov Institute’s collection applying the method of metabolomic profiling by I. G. Loskutov, T. V. Shelenga, A. V. Konarev, V. I. Khoreva, Yu. A. Kerv, E. V. Blinova, A. A. Gnutikov, A. V. Rodionov, L. L. Malyshev

“…Twenty-seven hulled and three naked oat varieties were selected for the study.The main objective of the work was to identify differences among common oat varieties with different degrees of breeding refinement at the level of metabolomic profiles. …”
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MetALD: Clinical aspects, pathophysiology and treatmentKeypoints by Jordi Gratacós-Ginès, Silvia Ariño, Pau Sancho-Bru, Ramon Bataller, Elisa Pose

“…Both conditions have many pathophysiological mechanisms in common, such as altered lipid and bile acid metabolism, and share some similar clinical features. …”
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An automated information extraction model for unstructured discharge letters using large language models and GPT-4 by Robert M. Siepmann, Giulia Baldini, Cynthia S. Schmidt, Daniel Truhn, Gustav Anton Müller-Franzes, Amin Dada, Jens Kleesiek, Felix Nensa, René Hosch

“…The administrative burden of manually extracting clinical information from discharge letters is a common challenge in healthcare. This study aims to explore the use of Large Language Models (LLMs), specifically Generative Pretrained Transformer 4 (GPT-4) by OpenAI, for automated extraction of diagnoses, medications, and allergies from discharge letters. …”
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A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases by Camila Perazzoli, Rogério S. Parra, Marley R. Feitosa, Enrico Sfoggia, Belinda Pinto Simões, José J. R. Rocha, Omar Féres

“…Based on an evaluation of common biological plausibility criteria, five factors were selected as the main predictors of hospital mortality in febrile neutropenic patients with colorectal disease. …”
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Detection of genetic sex using a qPCR-based method in the bigfin reef squid (Sepioteuthis lessoniana) by Yi-Chien Lee, Li-Lun Tang, Yu-Chen Yeh, Hau-Wen Li, Huei-Mien Ke, Cheng-Ju Yang, Chun-I Chiang, Chia-Hui Wang, Yung-Che Tseng, Ching-Fong Chang, Isheng Jason Tsai, Guan-Chung Wu

“…However, full-life cycle aquaculture remains challenging due to reproductive issues, particularly in later generations, where abnormal offspring production is common. One possible issue is sex reversal under culture conditions, possibly due to high temperatures and smaller egg sizes in later generations. …”
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Complex multivariate model predictions for coral diversity with climatic change by Tim R. McClanahan, Maxwell K. Azali, Nyawira A. Muthiga, Sean N. Porter, Michael H. Schleyer, Mireille M. M. Guillaume

“…We examined the predictions for numbers of coral taxa using all variables and compared them to models based on variables commonly used to predict climate change and human influences (eight and nine variables). …”
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Methods for modeling gestational weight gain: empirical application using electronic health record data from a safety net population by Anna Booman, Kimberly K. Vesco, Rachel Springer, Dang Dinh, Shuling Liu, Kristin Lyon-Scott, Miguel Marino, Jean O’Malley, Amy Palma, Teresa Schmidt, Jonathan M. Snowden, Kalera Stratton, Sarah-Truclinh Tran, Janne Boone-Heinonen

“…Differences included common first trimester weight loss in people with pre-pregnancy class II or III obesity and substantial first trimester weight gain in people with pre-pregnancy underweight, with the greatest pre-pregnancy BMI-related variation in GWG occurring in the second trimester. …”
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Prevalence and Subtypes Distribution (ST10, ST14, ST25, ST26) of Blastocystis spp. in Anatolian Water Buffalo (Bubalus bubalis) in Van, Türkiye by Adnan Ayan, Burcak Aslan Celik, Ozgur Yasar Celik, Ali Bilgin Yilmaz, Ozlem Orunc Kilinc, Ozge Oktay Ayan

“…ABSTRACT Background Blastocystis spp. is one of the most common protozoa worldwide, living in the gastrointestinal tract of humans and many other animals. …”
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