The spectrum-efficacy correlation of Kai-Xin-San for cognition of Aβ42 transgenic Drosophila and verification of its active ingredients by Jinfu Wu, Hang Sun, Yiyang Zhao, Lian Lian, Hongsheng Bian, Yong Guo, Dan Li, Lili Huang

“…Finally, the spectrum-effect relationship between the KXS fingerprint and memory improvement was analyzed, with the active ingredients subjected to validation testing.ResultsThe results identified seventeen common peaks in the fingerprint, and eight active components were determined: polygalaxanthone III, 3-6-disinapoylsucrose, ginsenoside Rg1, ginsenoside Rb1, β-asarone, α-asarone, dehydrotumulosic acid, and dehydropachymic acid. …”
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Anti-TNF-α Monoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease by Weigang Shu, Zhi Pang, Chunjin Xu, Jian Lin, Gengfeng Li, Wei Wu, Suofeng Sun, Junxiang Li, Xiuling Li, Zhanju Liu

“…Anemia is one of the most common complications in patients with inflammatory bowel disease (IBD). …”
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Reconstructing the genetic structure of the Kazakh from clan distribution data by M. K. Zhabagin, О. Е. Balanovsky, Zh. M. Sabitov, A. Z. Temirgaliyev, A. T. Agdzhoyan, S. M. Koshel, Е. М. Ramankulov, E. V. Balanovska

“…For Central Asian populations, particularly Kazakh, the clan affiliation serves as a good marker: a set of papers demonstrated that many clans include mainly persons which biologically descent from a recent common ancestor. In this study, we analyzed a large (~4.2 million persons) dataset on quasigenetic markers - the geographic distribution of 50 Kazakh clans at the beginning of the 20th century, and compared the dataset with the direct data of the Y-chro-mosomal diversity in modern Kazakh populations. …”
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Comparisons of CVID and IgGSD: Referring Physicians, Autoimmune Conditions, Pneumovax Reactivity, Immunoglobulin Levels, Blood Lymphocyte Subsets, and HLA-A and -B Typing in 432 Ad... by James C. Barton, Luigi F. Bertoli, J. Clayborn Barton

“…Common variable immunodeficiency (CVID) and immunoglobulin (Ig) G subclass deficiency (IgGSD) are heterogeneous disorders characterized by respiratory tract infections, selective Ig isotype deficiencies, and impaired antibody responses to polysaccharide antigens. …”
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Eliminating Postoperative Nausea and Vomiting in Outpatient Surgery with Multimodal Strategies including Low Doses of Nonsedating, Off-Patent Antiemetics: Is “Zero Tolerance“ Achie... by Susan J. Skledar, Brian A. Williams, Manuel C. Vallejo, Patricia L. Dalby, Jonathan H. Waters, Ronald Glick, Michael L. Kentor

“…Our approach toward “zero tolerance” of PONV emphasizes liberal identification of and prophylaxis against common risks.…”
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Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges by Weigao Zhang, Hu Liu, Danyang Zhang, Yuguo Yi, Liang Tao, Yunfeng Zhu, Shuxian Huang, Xunan Zhao, Qianchao Shao, Peiqi Li, Yiwen Weng, Wei Lu, Jianfa Zhang, Haibing Zhang, Yuxin Chen, Dan Weng

“…Our results demonstrated that hepatocyte-specific deficiency of RIPK1 sensitized the liver to short-term fasting-induced liver injury and hepatocyte apoptosis in both male and female mice. Despite being a common physiological stressor that typically does not induce liver inflammation, short-term fasting triggered hepatic inflammation and compensatory proliferation in hepatocyte-specific RIPK1-deficient (Ripk1-hepKO) mice. …”
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DETECTION, IDENTIFICATION, AND ANTIBIOTIC RESISTANCE PATTERNS OF FOODBORNE BACTERIAL AND FUNGAL PATHOGENS by Shakir Ullah, Hayat Khan, Usman Saeed, Ismail Shahid, Yasir Zubair, Maryam Bibi, Umair Islam, Basit Ali, Usman Shah, Muhammad Iqbal Khan Rahman

“…Background: Foodborne diseases are verry common and easily spread, among strains of Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, and Clostridium spp. …”
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Integrated analysis of chromatin and transcriptomic profiling of the striatum after cerebral hypoperfusion in mice by Shijia Le, Fengyiyang Xu, Zhi Luo, Weihao Shi, Shuangshuang Lu, Zengyu Zhang, Zimin Guo, Wenshi Xu, Mingqi Yang, Tianyi Li, Xu Li, Kun Liang, Lei Zhu

“…This study investigated the molecular and epigenetic changes in the striatum, a brain region critical for motor function and cognition, following chronic hypoperfusion using a bilateral common carotid artery stenosis (BCAS) model in mice. …”
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UPDATE ON CYTOMEGALOVIRUS INFECTION MANAGEMENT IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS by José Luis Piñana, Estela Giménez, Lourdes Vázquez, María Ángeles Marcos, Manuel Guerreiro, Rafael Duarte, Ariadna Pérez, Carlos de Miguel, Ildefonso Espigado, Marta González-Vicent, María Suarez-Lledó, Irene García-Cadenas, Rodrigo Martino, Angel Cedillo, Monserrat Rovira, Rafael de la Cámara, David Navarro, Carlos Solano

“…Background: Cytomegalovirus (CMV) infection is a common complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT) and in patients receiving novel hematological therapies. …”
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Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model by Huynh Man Anh, Dao My Linh, Vuu My Dung, Dang Thi Phuong Thao

“…Parkinson’s disease (PD) is a common neurodegenerative disorder and characterized by progressive locomotive defects and loss of dopaminergic neurons (DA neuron). …”
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The use of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for diagnosis of hepato-renal syndrome in advanced cirrhotic patients by Mohamed Adel Abd Elaziz, Asmaa Mustafa Gouda Elewa, Dina Zaki Mohamed Zaki Abdel Hamid, Nohier Essam Soliman Ahmed Hassan, Éva Csongrádi, Emad Hamdy Hamouda Mohammed, Mohammed Abdel Gawad

“…Background Chronic liver disease is a common and important clinical problem. Hepatorenal syndrome (HRS) is a life threatening complication. …”
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Evaluation of Comparative Efficacy of Ashwagandha (Withania somnifera) vs Brahmi (Bacopa monnieri Linn) on Stress Level and Quality of Sleep in the Subjects Experiencing Mental Str... by Mohnish Vijay Gokhale, Vaishali Kuchewar, Pankaj Yadav, Bhishmani Tarare

“…Ayurveda has described many herbs under ‘medhya rasayan’. Ashwagandha is commonly used than Brahmi. Brahmi is relatively easy to cultivate and inexpensive, hence this study is planned. …”
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Fishing on Facebook: Using Social Media and Citizen Science to Crowd-Source Trophy Murray Cod by Matthew O’Connell, Dirk Spennemann, Jennifer Bond, R. Keller Kopf, Nicole McCasker, Paul Humphries

“…This research has shown that low-cost marketing, combined with a widely dispersed, relatively common and well-known object of interest, can be effective at gaining participation in citizen science collaborations.…”
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Impact of Long COVID on Lung Function in Children by Zeynep Reyhan ONAY, Sinem CAN OKSAY, Deniz MAVI TORTOP, Gulay BILGIN, Yetkin AYHAN, Ferit DURANKUS, Saniye GIRIT

“…Within a median duration of 85 days (minimum-maximum: 35-194) following COVID-19 infection, a restrictive pattern was observed to be more common in the study group (p=0.021). In children with long COVID, 6MWT distances, DLCO Z-scores, and the predicted values of spirometry and lung volume tests were found to be significantly lower but in the normal range. …”
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Environmental impacts on childhood rhinitis: The role of green spaces, air pollutants, and indoor microbial communities in Taiyuan, a city in Northern China by Liu Yang, Huiyu Gao, Ying Wang, Dan Norbäck, Zhuohui Zhao, Xi Fu, Yu Sun, Xin Zhang

“…Rhinitis is one of the most common respiratory diseases, influenced by various environmental factors such as green space, air pollution and indoor microbiomes. …”
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Burden of psychiatric and somatic comorbidities in individuals with suicidal behavior: a nationwide Danish registry-based, observational study by Mette Reilev, Jens-Jakob Kjer Møller, Elsebeth Stenager, Erik Christiansen

“…Conclusions Psychiatric and somatic comorbidities commonly co-exist in individuals with suicidal behavior. …”
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Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis by D. V. Cherdantsev, O. V. Ovchinnikova, Yu. G. Trofimovich, I. G. Noskov, O. V. Pervova, A. A. Kovalenko

“…Secondary purulent peritonitis is a severe and fairly common form of abdominal infection with high mortality. …”
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Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG1 antibodies by Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter

“…These data provide experimental support for the common practice of using research-grade preparations of IgG1 as surrogates for immunogenicity risk assessment of their corresponding pharmaceutical counterparts.…”
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CT Angiography Assessment of Dorsal Pancreatic Artery and Intrapancreatic Arcade Anatomy: Impact on Whipple Surgery Outcomes by Gorkem Ozdemir, Tolga Olmez, Okan Dilek, Berkay Eyi, Alper Sozutek, Ahmet Seker

“…DPA was visualized in 55.98% (159/284) of patients, while the intrapancreatic arcade was observed in 25% (71/284). The most common origin of the DPA was the splenic artery in 69.2% (n = 110) of patients, followed by the superior mesenteric artery in 17.6% (n = 28). …”
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Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans by Jae-Young Yoo, Sook-Young Kim, Jung-Ah Hwang, Seung-Hyun Hong, Aesun Shin, Il Ju Choi, Yeon-Su Lee

“…Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types. …”
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