The value-for-money assessment and funding arrangements for high-priced drugs in an era of uncertainty: a comparative analysis of national health technology assessment agencies in... by Jihyung Hong, Eun-Young Bae, Sohee Cha, Joohyun Lee

“…Single-arm trials were more common in South Korea and England. Indirect comparison was the primary source of comparative effectiveness in England (70.0%), emphasising alignment with current practices. …”
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Red blood cell indices in different hemoglobinopathies: A cross-sectional study in Eastern India by Ayandip Nandi, Manas Talukdar, Saikat Bhattacharya, Susruta Sen, Supratik Biswas, Kuntal Roy

“…Introduction: Beta thalassemia and hemoglobin (HbE)-related hemoglobinopathies are common public health problems in developing countries. …”
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Higher detectability of amyloid with phenol Congo red compared with alkaline Congo red by Marta Legatowicz-Koprowska, Justyna Szczygieł, Małgorzata Mańczak, Ewa Walczak

“…Early diagnosis, when the deposits are minimal, determines the prognosis and requires histological confirmation. The commonly adopted gold standard technique is alkaline Congo red (ACR) staining, though its sensitivity is limited. …”
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. by Rana Zakerzade, Ching-Ho Chang, Kamalakar Chatla, Ananya Krishnapura, Samuel P Appiah, Jacki Zhang, Robert L Unckless, Justin P Blumenstiel, Doris Bachtrog, Kevin H-C Wei

“…Considering the elevated testes expression in many Drosophila species and the common ancestor, we suggest that the activity of SC genes in the male germline, while still poorly understood, may be a prime target of constant evolutionary pressures driving repeated adaptations and innovations.…”
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Immunosuppression for adult steroid-dependent or frequently relapsing nephrotic syndrome: A systematic review and meta-analysis. by Zhi Yong Wong, Chiu Yee Teo, Yan Qi Fiona Wong, Ka Ting Ng, Soo Kun Lim

“…<h4>Conclusion</h4>Among the commonly used immunosuppressive agents, only rituximab has a statistically significant effect in achieving complete remission among patients with SDNS/FRNS and has a relatively good safety profile, but this is limited by low quality of evidence with high degree of heterogeneity causing a lack of statistical power.…”
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Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

“…Immune checkpoint inhibitors (ICIs) frequently cause immune-related adverse events (irAEs), with thyroid irAEs being the most common endocrine-related irAEs. The incidence of overt thyroid irAEs was in the range of 8.9–22.2% in real-world settings, typically triggered by antibodies against PD-1 and PD-L1 and rarely by anti-CTLA-4 antibodies alone. …”
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Digital eye strain: prevalence and associated socio-demographic factors among banking assistants in Colombo District, Sri Lanka by Supipi Dissanayake Gunawardana, Dushyanthi Jayawaradana

“…With the excess usage, digital eye strain is now becoming the most common occupational hazard among the digital device users.   …”
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MAIP1-Related Tumor Immune Infiltration: As a Potential Prognostic Biomarker for Esophageal Cancer by Xiaoyu He, Fu Gan, Yongjian Lin, Guoqing Liu, Yunhua Lin, Dongxu Chen

“…Esophageal cancer (EC), a common malignant tumor of digestive tract, is also one of the most deadly cancers. …”
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METHAPHYSICS OF DEATH PENALTY by V. E. Gromov

“…Philosophical argumentation to justify death penalty is proposed as opposed to the common idea of inhuman and uncivilized nature of court practice of sentencing to death. …”
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Iron deficiency and fatigue in inflammatory bowel disease: A systematic review. by Stephanie Sartain, Maryam Al-Ezairej, Martin McDonnell, Catherine Westoby, Vasiliki Katarachia, Stephen A Wootton, J R Fraser Cummings

“…This systematic review examined the evidence of whether iron deficiency, with or without anaemia, was associated with fatigue in IBD. Fatigue is a common symptom in patients with IBD that can be difficult to manage and treat. …”
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Multicystic renal dysplasia, a histomorphological spectrum: Seven years experience from a tertiary care hospital by Kanika Gupta, Shramana Mandal, Varuna Mallya, Meeta Singh, Nita Khurana, Yogesh K. Sarin

“…It has an incidence of 1:4000 live births. They are more commonly diagnosed in boys, usually on the left side, but may also be bilateral. …”
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Corneal Nerve Parameter Reference Values for Chinese Adults Assessed by Corneal Confocal Microscopy by Juan Cao, Jingru Qu, Bekzod Odilov, Bin Lu, Yuanpin Zhang, Lili Li, Yuan Zhang, Qian Xiong, Yu Hong, Jianqiao Li, Yunfeng Shen, Xinguo Hou

“…Two experts captured and selected images of the central corneal subbasal nerve plexus at each center using the same corneal confocal microscopy instrument according to a commonly adopted protocol. Corneal nerve fiber density (CNFD), corneal nerve branch density (CNBD), and corneal nerve fiber length (CNFL) were measured using fully automated software (ACCMetrics). …”
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Global Financing Facility investments for vulnerable populations: content analysis regarding maternal and newborn health and stillbirths in 11 African countries, 2015 to 2019 by Mary Kinney, Meghan Bruce Kumar, Issa Kaboré, Joël Kiendrébéogo, Peter Waiswa, Joy E. Lawn

“…The investment cases commonly included comprehensive results frameworks, and PADs generally had less technical content and fewer indicators. …”
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Sustained-Release Fillers for Dentin Disinfection: An Ex Vivo Study by Bernhard Funk, Sharonit Sahar-Helft, David Kirmayer, Michael Friedman, Doron Steinberg

“…Enterococcus faecalis is the most commonly recovered species from failed root canal treatments. …”
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Analysis of MicroRNA -155-5p Expression in Patients with Primary Myelofibrosis. by Sarah I. Khaleel, Jaffar N. AlAlsaidissa

“…Objective: To investigate the expression level of MicroRNA-155-5p in patients with Primary Myelofibrosis compared to healthy controls and its correlation with common clinic-pathological factors. Methods: twenty-eight patients with Primary Myelofibrosis and twenty healthy subjects were examined as controls. …”
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Identification of an Inflammatory Response-Related Gene Signature to Predict Survival and Immune Status in Glioma Patients by Zhaoyue Yan, Yushuai Gao, Jinliang Yu, Zhiyuan Shen, Xingyao Bu

“…Background. Glioma is the most common primary brain tumor with high mortality and poor outcomes. …”
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Revealing Genomic Profile That Underlies Tropism of Myeloma Cells Using Whole Exome Sequencing by Youngil Koh, Daeyoon Kim, Woo-June Jung, Kwang-Sung Ahn, Sung-Soo Yoon

“…Genetic signature of cutaneous plasmacytoma shares that of melanoma implying common mechanism for skin tropism. KIAA1199, FRY, AP3B2, and OPTC are candidate genes for skin tropism of cancers.…”
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Disentangling self-management goal setting and action planning: A scoping review. by Stephanie Anna Lenzen, Ramon Daniëls, Marloes Amantia van Bokhoven, Trudy van der Weijden, Anna Beurskens

“…Although the phases we found are in accordance with commonly known frameworks for goal setting, it was striking that the majority of studies (n = 39, 67%) did not include all phases. …”
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How do lifestyle and environmental factors influence the sperm epigenome? Effects on sperm fertilising ability, embryo development, and offspring health by Ayazhan Akhatova, Celine Jones, Kevin Coward, Marc Yeste

“…Metabolic changes, such as high blood glucose levels and increased body weight, are commonly observed in the offspring of fathers subjected to chronic stress, in addition to an enhanced risk of depressive-like behaviour and increased sensitivity to stress in both the F0 and F1 generations. …”
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Extending the Meshless Natural-Neighbour Radial-Point Interpolation Method to the Structural Optimization of an Automotive Part Using a Bi-Evolutionary Bone-Remodelling-Inspired Al... by Carlos Oliveira, Ana Pais, Jorge Belinha

“…These models incorporate established design principles for material removal commonly used in vehicle suspension control arms. Additionally, the same models, along with a solid reference model, undergo linear static analysis under identical loading conditions used in the optimization process. …”
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