Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis by Yan Liu, Junjie Liu, Qin Wang, Kun Zhang, Chunyan Zhu, Duo Wang, Guanhua Qiu, Xiaoqi Zhu, Chao Fang

“…The delivered RSL3 that serves as a common ferroptosis inducer can reduce the levels of ferroptosis hallmarkers (eg, glutathione and glutathione peroxidase 4), break the redox homeostasis to magnify oxidative stress accumulation, promote the expression of ferroptosis-related proteins, and induce robust ferroptosis of tumor cells, accompanied with which systematic immune response activation can bbe realized. …”
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Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities by Maryam Kavianinia, Hadi Kalantar, Maryam Salehcheh, Layasadat Khorsandi, Saeedeh Shariati, Shokooh Mohtadi, Mohammad Javad Khodayar

“…Abstract Paraquat (PQ) toxicity is a common problem in the world, associated with oxidative stress, inflammation, and apoptosis. …”
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Latest Advances in Intersphincteric Resection for Low Rectal Cancer by Yifan Xv, Jiajun Fan, Yuan Ding, Yang Hu, Yingjie Hu, Zhengjie Jiang, Qingsong Tao

“…Although PCRT is employed to avoid positive circumferential resection margin (CRM) and decrease local recurrence, it tends to engender damage of anorectal function and patients’ quality of life (QoL). Common complications after ISR include anastomotic leakage (AL), anastomotic stricture (AS), urinary retention, fistula, pelvic sepsis, and prolapse. …”
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Prevalence of <i>Leptospira</i> spp. in Lithuanian Wild Boars (<i>Sus scrofa</i>) by Birutė Karvelienė, Inga Stadalienė, Jūratė Rudejevienė, Evelina Burbaitė, Dalia Juodžentė, Marius Masiulis, Jūratė Buitkuvienė, Jurgita Šakalienė, Gintaras Zamokas

“…The disease seems to be highly prevalent in environments where reservoir animals such as rats and small mammals are common. Even though leptospirosis in humans in Lithuania is rare, it remains a disease of significance in Europe. …”
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Osteoarthritis synovium as a nidus for monosodium urate crystal deposition inducing severe gout studied by label‐free stimulated Raman scattering combined with synovial organoids by Ziyi Chen, Wenjuan Wang, Yaxin Chen, Minbiao Ji, Yinghui Hua

“…Abstract Gout, a common chronic disease, is characterized by the formation and deposition of monosodium urate (MSU) crystal deposition in articular and nonarticular structures. …”
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RNF43 Mutations in IPMN Cases: A Potential Prognostic Factor by Xiao Yan Chang, Yan Wu, Ying Jiang, Peng Yan Wang, Jie Chen

“…An intraductal papillary mucinous neoplasm (IPMN) is a common pancreatic precursor lesion, and it often harbors mutations in KRAS, GNAS, and RNF43. …”
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Fine-Grained Lung Cancer Classification from PET and CT Images Based on Multidimensional Attention Mechanism by RuoXi Qin, Zhenzhen Wang, LingYun Jiang, Kai Qiao, Jinjin Hai, Jian Chen, Junling Xu, Dapeng Shi, Bin Yan

“…Lung cancer ranks among the most common types of cancer. Noninvasive computer-aided diagnosis can enable large-scale rapid screening of potential patients with lung cancer. …”
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Ginsenosides Rg1, Rb1 and rare ginsenosides: Promising candidate agents for Parkinson's disease and Alzheimer's disease and network pharmacology analysis by Mingchun Jiang, Jiaxin Chi, Yifan Qiao, Jinpeng Wang, Zhixin Zhang, Jia Liu, Xinhao Sheng, Liangjie Yuan

“…Ginseng has been commonly used as a traditional Chinese medicine in Asian countries for thousands of years. …”
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Relationship between Postural Deformities and Frontal Function in Parkinson’s Disease by Satoko Ninomiya, Akihiko Morita, Hiroko Teramoto, Takayoshi Akimoto, Hiroshi Shiota, Satoshi Kamei

“…Postural deformities and executive dysfunction (ED) are common symptoms of Parkinson’s disease (PD); however, the relationship between postural deformities and ED in patients with PD remains unclear. …”
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Isolated Vitamin D Deficiency Is Not Associated with Nonthyroidal Illness Syndrome, but with Thyroid Autoimmunity by Muyesser Sayki Arslan, Oya Topaloglu, Bekir Ucan, Melia Karakose, Basak Karbek, Esra Tutal, Mustafa Caliskan, Zeynep Ginis, Erman Cakal, Mustafa Sahin, Mustafa Ozbek, Tuncay Delibasi

“…Anti-TPO positivity was significantly more common in those with severe and moderate vitamin D deficiency, as compared to those with a normal 25(OH)D level. …”
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Identification and pharmacokinetics of saponins in Rhizoma Anemarrhenae after oral administration to rats by HPLC-Q-TOF/MS and HPLC-MS/MS by Wang Hai-Qiao, Lan Fen, Zhang Yi-Han, Xia Jin-Er, Gong Xiao-Mei, Liu Min

“…Rhizoma Anemarrhenae is a well-known herbal medicine with saponins as its commonly regarded major bioactive components. It is essential to classify the properties of saponins which are associated with their toxicity and efficacy. …”
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Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. by Zuzana Pavlíčková, Barbora Pafčo, Vladislav Ilík, Lee O'Brien Andersen, Milan Jirků, Kristýna Brožová, David Modrý, Oldřiška Kadlecová, Christen Rune Stensvold, Kateřina Jirků

“…In addition, we also investigated the influence of the common gut protist Blastocystis sp. on the human gut microbiota. …”
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m6A Reader PRRC2A Promotes Colorectal Cancer Progression via CK1ε‐Mediated Activation of WNT and YAP Signaling Pathways by Xi Wu, Shiyang Wang, Yuwei Pan, Mengzhen Li, Manyu Song, Hanfu Zhang, Min Deng, Xu Yang, Jiuzhi Xu, Shuo Zhang, Jinhua Zhang, Fengchao Wang, Maksim V. Plikus, Cong Lv, Lu Yu, Zhengquan Yu

“…Abstract Colorectal cancer (CRC) is the third most common cancer type and the second highest mortality rate among cancers. …”
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Improving Outcomes for Infants with Single Ventricle Physiology through Standardized Feeding during the Interstage by Cindy Weston, S. Adil Husain, Christopher L. Curzon, Steve Neish, Gemma T. Kennedy, Krista Bonagurio, Kevin Gosselin

“…Congenital heart disease is identified as the most common birth defect with single ventricle physiology carrying the highest mortality. …”
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Metastatic brain tumors: from development to cutting‐edge treatment by Guilong Tanzhu, Liu Chen, Jiaoyang Ning, Wenxiang Xue, Ce Wang, Gang Xiao, Jie Yang, Rongrong Zhou

“…Abstract Metastatic brain tumors, also called brain metastasis (BM), represent a challenging complication of advanced tumors. Tumors that commonly metastasize to the brain include lung cancer and breast cancer. …”
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Single-nucleus transcriptomes reveal the underlying mechanisms of dynamic whitening in thermogenic adipose tissue in goats by Manman Li, Nange Ma, Shujie Luo, Yuyi Lu, Xixi Yan, Yang Li, Xinmei Li, Zhuohui Li, Zhipei Wu, Zhenyu Wei, Wei Wang, Huimei Fan, Yu Jiang, Yan Xiong, Yu Wang

“…Furthermore, trajectory analysis revealed beige- and white-like adipocytes deriving from a common origin, coexisting and undergoing the transdifferentiation. …”
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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

“…The previous study demonstrates that benzbromarone (BBR), a commonly prescribed pharmaceutical agent for managing gout and hyperuricemia, exacerbates hepatic steatosis and liver injury specifically in obese individuals. …”
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An mRNA-Based Respiratory Syncytial Virus Vaccine Elicits Strong Neutralizing Antibody Responses and Protects Rodents Without Vaccine-Associated Enhanced Respiratory Disease by Jianglong Li, Haiyan Long, Shaoyi Chen, Zhendong Zhang, Shuang Li, Qi Liu, Jun Liu, Jiaru Cai, Liping Luo, Yucai Peng

“…Background: Respiratory syncytial virus (RSV) causes the most common type of severe lower respiratory tract infection worldwide, and the fusion (F) protein is a target for neutralizing antibodies and vaccine development. …”
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Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy by Xiaopeng Li, Yang Zhong, Pengyuan Qi, Daoming Zhu, Chenglong Sun, Nan Wei, Yang Zhang, Zhanggui Wang

“…Radiotherapy (RT) is one of the most common treatments for cancer. However, intracellular glutathione (GSH) plays a key role in protecting cancer from radiation damage. …”
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Home-based transcranial direct current stimulation paired with cognitive training to reduce fatigue in multiple sclerosis by Leigh Charvet, Judith D. Goldberg, Xiaochun Li, Pamela Best, Matthew Lustberg, Michael Shaw, Lana Zhovtis, Josef Gutman, Abhishek Datta, Marom Bikson, Giuseppina Pilloni, Lauren Krupp

“…Abstract Fatigue is a common and often debilitating feature of multiple sclerosis (MS) that lacks reliably effective treatment options for most patients. …”
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