Developing a Clustering-Based Empirical Bayes Analysis Method for Hotspot Identification by Yajie Zou, Xinzhi Zhong, John Ash, Ziqiang Zeng, Yinhai Wang, Yanxi Hao, Yichuan Peng

“…To overcome this possible heterogeneity problem, EB-based HSID methods that use common clustering methodologies (e.g., mixture models, K-means, and hierarchical clustering) to select “similar” sites for building SPFs are developed. …”
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Efficacy of dietary modifications and mucosal protectors in the treatment of laryngopharyngeal reflux: a multicenter study by Matteo Gelardi, Rossana Giancaspro, Christian Fiorentino, Stefano Patruno, Jacopo Marroni, Alessandro D’Avino, Letizia Neri, Michele Cassano, Giampiero Neri

“…The use of proton pump inhibitors (PPIs) is widely established in common practice and derives from the standard approach of using PPIs to treat patients with gastroesophageal reflux disease (GERD). …”
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Effect of biannual azithromycin on respiratory pathogens among symptomatic children: results from the randomised Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résista... by Jie Liu, Thomas M Lietman, Jeremy D Keenan, Kieran S O'Brien, Elodie Lebas, Amza Abdou, Benjamin F Arnold, James A Platts-Mills, Eric R Houpt, Stephanie A Brennhofer, Elizabeth T Rogawski McQuade, Ramatou Maliki, Jixian Zhang, Suzanne Stroup, Suporn Pholwat, Ahmed M Arzika

“…Swabs were tested by quantitative PCR using a customised TaqMan Array Card that included assays for 19 respiratory pathogens.Results Nasopharyngeal detection of Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae was common in both azithromycin and placebo communities. …”
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Epidemiological Characteristics of Hospitalized Burn Patients—A 10-Year Retrospective Study in a Major Burn Center in Serbia by Marina Stojanović, Milana Marinković, Milana Jurišić, Biljana Miličić, Milan Stojičić, Milan Jovanović, Jelena Jeremić, Nemanja Dimić, Svetlana Srećković, Irina Drača Cetušić, Marko Jović

“…Regarding etiology, flame was the most common (49.0%). Patient comorbidities were noted on admission in 50.1% of cases. …”
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Impaired network organization in mild age‐related hearing loss by Zhaopeng Tong, Chunhua Xing, Xiaomin Xu, Jin‐Jing Xu, Yuanqing Wu, Richard Salvi, Xindao Yin, Fei Zhao, Yu‐Chen Chen, Yuexin Cai

“…Abstract Age‐related hearing loss (ARHL) is considered one of the most common neurodegenerative disorders in the elderly; however, how it contributes to cognitive decline is poorly understood. …”
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Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb by Inder Sehgal, Wallace D. Winters, Michael Scott, Andrew David, Glenn Gillis, Thaya Stoufflet, Anand Nair, Konstantine Kousoulas

“…Aloe vera, a common ingredient in cosmetics, is increasingly being consumed as a beverage supplement. …”
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Exosomal non-coding RNAs in the regulation of bone metabolism homeostasis: Molecular mechanism and therapeutic potential by Chengxiong Huang, Yu Xiao, Liming Qing, Juyu Tang, Panfeng Wu

“…Osteoporosis (OP), osteoarthritis (OA) and femoral head necrosis (ONFH) are common metabolic bone diseases. At present, the treatment of metabolic bone disease is still mainly to relieve pain and improve joint function. …”
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Variants in the 3′ End of SLC6A3 in Northwest Han Population with Parkinson’s by Peiye Chang, Yongwang Fu, Ping Zhao, Chunmei Wang, Mingfang Jiang, Rui Li, Yulin He

“…Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in neurology. It is possible that multifactorial and genetic factors are related to its pathogenesis. …”
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Factors Associated with the Incidence and Severity of New-Onset Atrial Fibrillation in Adult Critically Ill Patients by Péricles A. D. Duarte, Gustavo Elias Leichtweis, Luiza Andriolo, Yasmim A. Delevatti, Amaury C. Jorge, Andreia C. Fumagalli, Luiz Claudio Santos, Cecilia K. Miura, Sergio K. Saito

“…Acute Atrial Fibrillation (AF) is common in critically ill patients, with significant morbidity and mortality; however, its incidence and severity in Intensive Care Units (ICUs) from low-income countries are poorly studied. …”
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Whole genome sequencing in early onset advanced heart failure by Erik Linnér, Tomasz Czuba, Olof Gidlöf, Jakob Lundgren, Entela Bollano, Maria Hellberg, Selvi Celik, Neha Pimpalwar, Philipp Rentzsch, Molly Martorella, Anders Gummesson, Olle Melander, Sebastian Albinsson, Göran Dellgren, Jan Borén, Anders Jeppsson, R. Thomas Lumbers, Sonia Shah, Johan Nilsson, Pradeep Natarajan, Tuuli Lappalainen, Malin Levin, Hans Ehrencrona, J. Gustav Smith

“…A family history was more common in LP/P variant carriers than in non-carriers but was present in less than half of carriers (44% vs 13%, P < 0.001), whereas age was similar. …”
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Excellent Silicon Surface Passivation Achieved by Industrial Inductively Coupled Plasma Deposited Hydrogenated Intrinsic Amorphous Silicon Suboxide by Jia Ge, Muzhi Tang, Johnson Wong, Zhenhao Zhang, Torsten Dippell, Manfred Doerr, Oliver Hohn, Marco Huber, Peter Wohlfart, Armin G. Aberle, Thomas Mueller

“…It is found that the hydrogen content in the film is much higher than what is commonly reported in intrinsic amorphous silicon due to oxygen incorporation. …”
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Effect of Physician-Delivered Patient Education on the Quality of Bowel Preparation for Screening Colonoscopy by Tze-Yu Shieh, Ming-Jen Chen, Chen-Wang Chang, Chien-Yuan Hung, Kuang-Chun Hu, Yang-Che Kuo, Shou-Chuan Shih, Horng-Yuan Wang

“…Inadequate bowel preparation is common in outpatients undergoing screening colonoscopy because of unawareness and poor adherence to instruction. …”
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Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy by Wenhua Xu, Mingshan Ren, Swagata Ghosh, Kai Qian, Zhaofeng Luo, Aimei Zhang, Cuiping Zhang, Jiajun Cui

“…Intravenous immunoglobulin (IVIg) is an expensive and commonly used immunotherapeutic approach to treat patients with MG. …”
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Integrating Social Relationships and Personality into MAS-Based Group Recommendations by Ariel Monteserin, Daiana Elin Madsen, Daniela Godoy, Silvia Schiaffino

“…Multi-agent systems can be used to develop such recommendations, where multiple intelligent agents interact with each other to achieve a common goal, i.e., deciding which item to recommend. …”
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The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis by Min-kyung Yeo, Ja Seong Bae, Sohee Lee, Min-Hee Kim, Dong-Jun Lim, Youn Soo Lee, Chan Kwon Jung

“…However, WLPTCs were more commonly associated with Hashimoto’s thyroiditis than classic PTCs (93% versus 36%, resp., P < 0.001) and showed significantly lower rate of BRAF mutation when compared to classic PTCs (65% versus 84%, resp., P = 0.007). …”
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The Age-Specific Association of Waist Circumference and Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus in Shandong, China by Lingling Xu, Weihong Yu, Ping Huang, Chunying Li, Yan Li, Meng Wang, Qun Xu, Jing Wang, Caixia Zheng, Bin Qu, Yanping Zhao, Meng Niu, Ou Wang, Fengying Gong

“…To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). …”
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A Novel CRYBB2 Stopgain Mutation Causing Congenital Autosomal Dominant Cataract in a Chinese Family by Yu Zhou, Yaru Zhai, Lulin Huang, Bo Gong, Jie Li, Fang Hao, Zhengzheng Wu, Yi Shi, Yin Yang

“…Congenital cataract is the most common cause of the visual disability and blindness in childhood. …”
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X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women by Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu

“…Abstract The incidence of pituitary adrenocorticotropic hormone (ACTH)-secreting PitNETs, commonly known as ACTH PitNETs, is significantly higher in females; however, the underlying causes for this gender disparity remain unclear. …”
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Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice by Jie Li, Yuanjie Guo, Liyuan Ma, Yixiang Liu, Chao Zou, Huiying Kuang, Bing Han, Yingliang Xiao, Yanbo Wang

“…In this study, alginate oligosaccharide (AOS) and cyanidin-3-O-glucoside (C3G) were selected as a common marine plant oligosaccharide and terrestrial plant polyphenol, respectively, to study their effects on intestinal health. …”
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An analysis of the cultivation, consumption and composition of home-grown cannabis following decriminalisation in the Australian Capital Territory by Cilla Zhou, Isobel Lavender, Rebecca Gordon, Danielle McCartney, Richard C. Kevin, Miguel A. Bedoya-Pérez, Iain S. McGregor

“…Various cultivation challenges were identified, most commonly mould, nutrient deficiency and spider mites. …”
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