Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia by Stephen E. Langabeer, Karl Haslam, Maria Anne Smyth, John Quinn, Philip T. Murphy

“…Alternatively, both malignancies possibly evolved from a common precursor defined by a predisposition mutation with divergent evolution into MPN through acquisition of the JAK2 V617F and AML through acquisition of different mutations. …”
Get full text

Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein by Ioannis Papaioannou, J. Paul Simons, James S. Owen

“…In particular, we discuss the possibility and potential benefit of applying in combination two technical advances to repair aberrant APOE genes: (i) an engineered endonuclease to introduce a double-strand break (DSB) in exon 4, which contains the common, but dysfunctional, ε2 and ε4 alleles; (ii) an efficient and selectable template for homologous recombination (HR) repair, namely, an adeno-associated viral (AAV) vector, which harbours wild-type APOE sequence. …”
Get full text

Aplastic Anemia Treated with Eltrombopag during Pregnancy by Yuri Suminaga, Yoshitsugu Chigusa, Tadakazu Kondo, Haruko Okamoto, Yosuke Kawamura, Mana Taki, Masaki Mandai, Haruta Mogami

“…In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common. Nevertheless, only supportive care with blood products is the mainstay of treatment of aplastic anemia in pregnancy. …”
Get full text

An Investigation of Time-Dependent Deformation Characteristics of Soft Dredger Fill by Wanying Wang, Qingzi Luo, Bingxiang Yuan, Xiaoping Chen

“…However, the lateral deformation of soils is not allowed during the commonly used one-dimensional consolidation tests, which cannot describe the real deformation features of soils in practice. …”
Get full text

Residents’ perspectives on tourism impacts of Portuguese World Heritage historic centers: Angra do Heroísmo and Évora by Laurentina Vareiro, Raquel Mendes

“…The comparison of the mean scores of these impacts across residents that live near and far from the historic centers reveals that the most valued and least valued impacts in the three categories of impacts (economic, social and cultural, and environmental) are common to all groups of residents. Nevertheless, residents living in or near the historic center of Angra do Heroísmo have higher means in the majority of tourism impacts (in all categories), with only one negative impact to concern the majority of respondents. …”
Get full text

Teachers’ Perspectives on Behavioral and Emotional Problems among School-going Adolescents in Kashmir: Examining the Risk Correlates of Behavioral and Emotional Problems by Danishwar Rasool Dar, G. Lakshmana

“…Background: Political violence in Kashmir was a common occurrence. The phenomenon had occurred often and repeatedly in an unmanageable fashion. …”
Get full text

A disproportionality analysis of FDA adverse event reporting system events for misoprostol by Li Yang, Wenting Xu

“…After analyzing 17,427,762 adverse event reports, a total of 2032 adverse events reports related to misoprostol were identified, involving 23 system organ classes and 30 preferred terms. The most common AEs were foetal exposure during delivery(n = 201), uterine tachysystole(n = 95), uterine rupture (n = 95), and heart rate decreased (n = 93). …”
Get full text

Economic Potentials and Use Dynamics of Sorghum Food System in Ethiopia: Its Implications to Resolve Food Deficit by Teshome Sirany, Esubalew Tadele, Haimanot Aregahegn, Dagnachew Wale

“…This review initiates one of the most common food grains grown in the poorest countries and the most food-insecure regions of the nation. …”
Get full text

Detection of Two-Phase Slug Flow Film Thickness by Ultrasonic Reflection by Deddy Kurniadi, Narendra Kurnia Putra, Lalu Febrian Wiranata

“…Slug flow is a common phenomenon in closed pipes, occurring in two-phase flow where liquid and gas phases mix, impacting the custody transfer or the efficiency of chemical reactions. …”
Get full text

Nonlinear Behavior Study of Reinforced Concrete Coupling Beams Subjected to the Effect of Wind Loading by Sarah Bashour, Bassam Hwaija, Fadwa Issa

“…For seismic design of such buildings, performance-based design has been commonly used in regions with strong earthquakes for its ability to achieve economical and safe design, however the use of performance-based wind design (PBWD), which permits nonlinear response of ductile elements at specific locations under wind loads is still hindered due to the lack of information regarding the performance of these elements. …”
Get full text

EFFICIENCY ANALYSIS OF THE INSURANCE SECTOR IN BOSNIA AND HERZEGOVINA by Mirza Šikalo, Almira Arnaut-Berilo

“…Efficiency measurement was performed using the nonparametric Data Envelopment Analysis (DEA) technique as the most commonly used tool for efficiency analysis in finance. …”
Get full text

Experimental Investigation of Concrete-Infilled Bamboo for Structural Performance in Compression for Low-Cost Building by Sam Bulolo, James Gowon Okuda, Michael Kyakula

“…A total of four samples of bamboo of five different lengths (0.2, 0.4, 0.6, 0.8, and 1 m) were prepared with concrete (concrete infilled) and without concrete for three different commonly used concrete grades (C12/15, C15/20, and C20/25) and the load-carrying capacity tested to determine its resistance under compression. …”
Get full text

Heart rhythm disorders and features of their management at COVID-19 pandemic by Yu.M. Mostovoy, T.D. Danilevych

“…Among them, the most common are myocarditis, cardiomyopathies, myocardial infarction, pulmonary embolism and cardiac arrhythmias. …”
Get full text

An Analysis of the Progression of Conjunctivalisation after Transplantation of Cultivated Corneal Epithelium by Dariusz Dobrowolski, Boguslawa Orzechowska-Wylegala, Bogumil Wowra, Ewa Wróblewska-Czajka, Maria Grolik, Edward Wylegala

“…Local ingrowth of the conjunctiva is a common complication after the transplantation of cultivated epithelial cells. …”
Get full text

Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism by Xiaoya Wang, Kang Zhang, Jingyan Zhang, Guowei Xu, Zhiting Guo, Xiaorong Lu, Chunhua Liang, Xueyan Gu, Liping Huang, Shuqi Liu, Lei Wang, Jianxi Li

“…Acute lung injury (ALI) is a common respiratory disease, Cordycepin has been reported to reduce ALI, which is an effective component in Cordyceps militaris solid medium extract (CMME). …”
Get full text

Dysphotopsia after uneventful phacoemulsification by Mohammed A. Mohammed

“…Conclusion Patients now anticipate satisfaction from cataract surgery, which is becoming a common procedure. Both the patient and the surgeon may become frustrated when dysphotopsia occurs, which incidentally occurs in a flawlessly performed procedure. …”
Get full text

Typology of Personalization in Recommender Systems by Marziyeh Nourahmadi, Hojjatollah Sadeqi

“…This data generated by different users share many common patterns that can be filtered and analyzed to make recommendations for a product, goods, or service of interest to users. …”
Get full text

Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research by Nicholas J. Snow, Katie P. Wadden, Arthur R. Chaves, Michelle Ploughman

“…Central motor conduction time and motor-evoked potentials were the most commonly used TMS techniques and showed relationships with disease severity, motor impairment, and fatigue. …”
Get full text

Context-dependent modulation of spatial attention: prioritizing behaviourally relevant stimuli by Noah Britt, Jackie Chau, Hong-jin Sun

“…Over time, we learn to allocate attention resources towards stimuli that are behaviourally relevant to ongoing action, leading to attention capture by meaningful peripheral stimuli. A common example includes, while driving, stimuli that imply a possibly hazardous scenario (e.g. a pedestrian about to cross the road) warrant attentional prioritization to ensure safe proceedings. …”
Get full text

The Homeopathic Preparation Neurexan® vs. Valerian for the Treatment of Insomnia: An Observational Study by Rainer Waldschütz, Peter Klein

“…Insomnia is prevalent and complementary therapies are common, but data are lacking on the effectiveness and tolerability of preparations beyond valerian. …”
Get full text