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26881
T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint pr...
Published 2023-01-01“…Recent evidence demonstrated that galectin-9 is highly expressed in a wide range of human malignancies including the most aggressive tumors, such as high-grade glioblastomas and pancreatic ductal adenocarcinomas, as well as common malignancies such as breast, lung and colorectal cancers. …”
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26882
Global, regional and national burden of neuroblastoma and other peripheral nervous system tumors, 1990 to 2021 and predictions to 2035: visualizing epidemiological characteristics...
Published 2025-02-01“…Background: Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children, accounting for >15 % of cancer-related deaths in children. …”
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26883
A retrospective multicenter study on the efficacy and safety of disitamab vedotin monotherapy versus combination with anti-PD-1 immunotherapy in advanced gastric cancer
Published 2025-01-01“…Furthermore, the most common grade 3–5 treatment-related adverse events (TRAEs) included decreased white-blood-cell (WBC) count, decreased neutrophil count, and anemia. …”
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26884
Application of Minimally Invasive Oral Swab Samples for qPCR-Based Sexing in Neognathae Birds
Published 2025-01-01“…A total of 34 samples were included in this study from the following 17 bird species: domestic pigeon (<i>Columba livia domestica</i>), domestic chicken (<i>Gallus gallus domesticus</i>), domestic goose (<i>Anser anser f domesticus</i>), domestic duck (<i>Anas platyrhynchos domesticus</i>), Mute swan (<i>Cygnus olor</i>), Budgerigar (<i>Melopsittacus undulatus</i>), Lovebird (<i>Agapornis roseicollis</i>), Cockatiel (<i>Nymphicus hollandicus</i>), Red-rumped parrot (<i>Psephotus haematonotus</i>), Rose-ringed parakeet (<i>Psittacula krameri</i>), African grey parrot (<i>Psittacus erithacus</i>), domestic Canary (<i>Serinus canaria forma domestica</i>), Goldfinch (<i>Carduelis carduelis major</i>), Gouldian Finch (<i>Chloebia gouldiae</i>), Red Siskin (<i>Carduelis cucullata</i>), Australian Zebra Finch (<i>Taeniopygia castanotis</i>), and Common buzzard (<i>Buteo buteo</i>). The results proved <i>that</i> the <i>CHRNA6</i>, <i>DDX4</i>, <i>VPS13A</i>, <i>LPAR1</i>, and <i>TMEM161B</i> genes can reveal the sexes in the <i>Neognath</i> birds tested.…”
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26885
Assessment of The Factors Affecting Management of Gender and Sexual Violence Against Women in Rural Communities: A Case Study of Kyanamira Sub County Kabale District.
Published 2024“…In addition, fair SGBV cases hearing discrepancies were common and found to negatively affect more women. …”
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26886
Hypothyroidism impairs the circadian rhythmicity of clock genes and proteins involved in gut nutrient absorption in female mice
Published 2025-01-01“…Hypothyroidism is a common thyroid dysfunction with a higher prevalence in women. …”
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26887
World Health Organization priority antimicrobial resistance in Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecium hea...
Published 2025-03-01“…Carbapenem-resistant Klebsiella pneumoniae (CRKP) was the most common CRE, corresponding to 14.2% of all BSIs. A. baumannii isolates presented the highest proportion of WPAP (87.8%). …”
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26888
Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small...
Published 2024-01-01“…Background and aim: Non-small cell lung cancer (NSCLC) is the most common lung cancer found in elderly patients. Aging and chronic inflammation are related to its pathogenesis. …”
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26889
Accuracy of Artificial Intelligence Based Chatbots in Analyzing Orthopedic Pathologies: An Experimental Multi-Observer Analysis
Published 2025-01-01“…<b>Methods:</b> 30 fictitious case vignettes of common conditions in trauma surgery and orthopedics were retrospectively examined by four orthopedic and traumatology specialists and four different symptom checker apps for diagnostic accuracy and the recommended urgency of measures. …”
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26890
Cyberinfrastructure for machine learning applications in agriculture: experiences, analysis, and vision
Published 2025-01-01“…These components included (1) a UAS imagery pipeline that reduced processing time and improved image quality over standard methods, (2) a tabular data pipeline that aggregated data from multiple sources and temporal resolutions and aligned it with a common temporal resolution, (3) an approach to adapting the model architecture for a vision transformer (ViT) that incorporates agricultural domain expertise, and (4) a data visualization prototype that was used to identify outliers and improve trust in the data.DiscussionFurther work will be aimed at maturing the CI components and implementing them on high performance computing (HPC). …”
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26891
Tracking acute flaccid paralysis in Niger: a half-decade epidemiological portrait (2016–2021)
Published 2025-01-01“…Fever onset (90.13%), asymmetric paralysis (80.33%), and a 3-day AFP progression (80.48%) were common. cVDPV2 was found in 33 cases, predominantly in Zinder province. …”
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26892
Two decades of recipient and donor referrals for heart transplantation to Groote Schuur Hospital, Cape Town, South Africa: A retrospective study
Published 2024-04-01“…Poor social circumstances (n=38; 39.6%), poor insight (n=28; 29.2%) and poor compliance (n=21; 21.9%) were the most common non-medical reasons for not listing recipients, while obesity (n=30; 31.3%) and smoking (n=23; 24.0%) were notable medical contraindications. …”
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26893
Predictors of Colorectal Cancer Screening and Screening Modalities among Patients seen at Federally Qualified Health Centers Funded by the United States Health Resources and Servic...
Published 2025-02-01“…Conclusion: Federally qualified health center patients reported endoscopic CRC screening more commonly than stool-based screening, and barriers to access such as distance to the health center and English proficiency were impactful. …”
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26894
Tracheostomy Practice in the Italian Intensive Care Units: A Point-Prevalence Survey
Published 2025-01-01“…Neurological conditions were identified as the most common reason for ICU admission, accounting for 48.4% of cases. …”
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26895
Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial
Published 2024-12-01“…Among 25 enrolled participants, the mean age was 65.3 ± 9.9 years, 68% were male, and 88% were White. The most common types of cancers were pancreatic (44%), hepatobiliary (20%), and colorectal (12%); reasons for aborting surgery were occult metastatic disease (52%) and local unresectability (36%). …”
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26896
Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey
Published 2025-01-01“…Volume control ventilation mode, 4 to 6 mL per kilogram of predictive body weight, pure oxygen inspiration, and a low-level positive end-expiratory pressure ≤ 5 cm H2O were the most popular ventilation parameters. The most common thresholds of intraoperative respiration monitoring were peripheral oxygen saturation (SpO2) of 90–94%, end-tidal CO2 of 45 to 55 mm Hg, and an airway pressure of 30 to 34 cm H2O. …”
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26897
Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes
Published 2025-02-01“…They include 10,13-epoxy-11-methyl-octadecan-10,12-dienoic acid, which has been identified in the lipid fraction of latex from two Hevea brasiliensis genotypes commonly known as the source of natural rubber. Those two genotypes, namely RRIM501 and PB235, are from Rubber Research Institute of Malaysia (RRIM) and Prang Besar, Malaysia (PB), respectively. …”
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26898
CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials
Published 2025-01-01“…By building on established nanoinformatics frameworks, such as those developed in the H2020-funded projects NanoSolveIT and NanoCommons, CompSafeNano addresses critical challenges in nanosafety through development and integration of innovative methodologies, including advanced in vitro models, in silico approaches including machine learning (ML) and artificial intelligence (AI)-driven predictive models and 1st-principles computational modelling of NMs properties, interactions and effects on living systems. …”
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26899
Compaction of Hyaloclastite from the Active Geothermal System at Krafla Volcano, Iceland
Published 2020-01-01“…Hyaloclastites commonly form high-quality reservoir rocks in volcanic geothermal provinces. …”
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26900
Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment
Published 2025-02-01“…Using a large stroke registry, we investigated whether 2 commonly used statins, rosuvastatin and atorvastatin, differ in their effectiveness in reducing the risk of vascular events in patients with acute ischemic stroke. …”
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