Molecular Mechanisms of Synergistic Effect of PRIMA‐1met and Oxaliplatin in Colorectal Cancer With Different p53 Status by Xiao‐lan Li, Jianbiao Zhou, Nicole Xin‐Ning Tang, Yi Chai, Meng Zhou, Ai‐di Gao, Zhong‐kai Lu, Han Min

“…ABSTRACT Background The toxicity and drug resistance associated with oxaliplatin (L‐OHP) limit its long‐term use for colorectal cancer (CRC) patients. p53 mutation is a common genetic trait of CRC. PRIMA‐1met (APR‐246, eprenetapopt) restores the DNA‐binding capacity of different mutant P53 proteins. …”
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Etoposide targets 2A protease to inhibit enterovirus 71 replication by Qinqin Liang, Sai Shi, Qingjie Zhang, Yaxin Wang, Sheng Ye, Binghong Xu

“…We identified a derivative of a traditional herbal monomer, Etoposide, commonly isolated from the roots and rhizomes of Podophyllum spp. …”
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Pembentukan Daftar Stopword Menggunakan Term Based Random Sampling Pada Analisis Sentimen Dengan Metode Naïve Bayes (Studi Kasus: Kuliah Daring Di Masa Pandemi) by Raditya Rinandyaswara, Yuita Arum Sari, Muhammad Tanzil Furqon

“…The stopword list that is commonly used is in the form of a digital library whose list is already available, but not all words contained in the digital library are irrelevant words in certain data. …”
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Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

“…The study included non-immunocompromised patients 18 years of age or younger with infections caused by GNB isolated from a sterile site or nonsterile site in the setting of clinical infection.Results: A total of 810 episodes of infection with GNB in 674 pediatric patients were identified. The most common pathogens were Enterobacterales followed by Pseudomonas. …”
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Early removal of indwelling urinary catheters in children undergoing abdominal tumor resection with epidural analgesia by Shachi Srivatsa, Jennifer H. Aldrink, Dana Schwartz, Grant Heydinger, Andrew Davidoff, Andrew J. Murphy, Kyle O. Rove, Sara A. Mansfield

“…Purpose: Epidural analgesia (EA) is commonly employed for postoperative pain management in children undergoing abdominal tumor resection. …”
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Three-dimensional structure of entire hydrated murine hearts at histological resolution by Jasper Frohn, Frederik Böddeker, Marius Reichardt, Hendrik Bruns, Titus Czajka, Amara Khan, Ludovic Broche, Michael Krisch, Alberto Bravin, Frauke Alves, Jana Zschüntzsch, Tim Salditt

“…All datasets have been analyzed using semi-automated image segmentation of the ventricles, rotation into a common coordinate system, classification into different anatomical compartments, and finally the structure tensor approach. …”
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Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…The median time to onset was 26–31 days for ivosidenib and enasidenib. AML was the most common indication in the differentiation syndrome reports. …”
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Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study by Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

“…Completing multiple prescreeners (301/501, 60.1%) and providing invalid addresses (156/501, 31.1%) were the most common reasons prescreeners were flagged. An additional 1% (18/1928) of prescreeners were flagged as potentially deceptive during the subsequent study screening and enrollment phone call. …”
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Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats by Yongting Zhang, Yuwen Li, Wenting Li, Jie Cai, Ming Yue, Longfeng Jiang, Ruirui Xu, Lili Zhang, Jun Li, Chuanlong Zhu

“…Previous studies have shown that the concentration of hepatocyte growth factor (HGF) in the injured liver was significantly increased. HGF is commonly known as the ligand of c-Met. The level of c-Met in hUC-MSCs as detected by Western blotting indicated that at a higher passage number, there is a decrease in c-Met. …”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…We discovered that the commonly discussed forms of skin ageing (i.e., wrinkles, pigmentation, and photo-ageing) only accounted for a small portion (24.39%) of the variance of all skin ageing phenotypes in our study population. …”
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Poutníci a jejich peníze na cestě do Říma. Zamyšlení nad edicí Il Libro del pellegrino (Siena, 1382–1446) by Roman Zaoral

“…At average expense of 3 Prague groschens per day which roughly corresponds with the most common summer daily wage of a journeyman, a pilgrim was able to manage for about 85 days with 4 pounds of Prague groschens, it was enough for a return journey and for about ten days ́ stay in Rome. …”
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Anti-blastocystis activity of hop extracts in vitro by S.I. Pokhil, V.V. Kazmirchuk, O.M. Tymchenko, V.Y. Yevsiukova, A.L. Melnyk

“…Blastocystis sp. are the most common, unicellular, anaerobic parasites of the intestinal tract of many animal and human species that can cause various digestive diseases. …”
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The prognostic value of systemic immune-inflammation index in patients with unresectable hepatocellular carcinoma treated with immune-based therapy by Tian He, Bin Xu, Lu-Na Wang, Zi-Yi Wang, Huan-Chen Shi, Cheng-Jie Zhong, Xiao-Dong Zhu, Ying-Hao Shen, Jian Zhou, Jia Fan, Hui-Chuan Sun, Bo Hu, Cheng Huang

“…ROC curves confirmed that SII had superior predictive accuracy compared to common clinical indicators, with predictive relevance even in AFP-negative patients. …”
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Hubungan Antara Tingkat Aktivitas Fisik dengan Fungsi Kognitif pada Usila di Kelurahan Jati Kecamatan Padang Timur by Milfa Sari Muzamil, Afriwardi ., Rose Dinda Martini

“…<br />Kata kunci: fungsi kognitif, aktivitas fisik, usia lanjut</p><p>Abstract<br />Cognitive impairment is common and highly age-related in the world. The prevalence of cognitive impairment is high in the country with high proportion of elderly. …”
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Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland by Saleh Aljadeeah, Seyed-Moeen Hosseinalipour, Nataliia Khanyk, Eszter Szocs, Aliki Traianou, Ana Tomas, Chrysanthi Tatsi, Elżbieta Czapka, Alessandro Verona, Tessa van Boekholt, Ion Chesov, Apostolos Veizis

“…This study aims to address this gap by analyzing data from INTERSOS clinics at the Moldovan and Polish borders with Ukraine to identify the common health conditions prompting people to seek healthcare services during transit. …”
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The Relationship Between Serum 25 hydroxy Vitamin D Deficiency and Dietary Pattern in Baxshin Hospital, Sulaimani City by Mohammed I M Gubari, Jeza Muhamad Abdul Aziz, Fadhil Ahmed Mohialdeen, Khalid Anwar Hama-Ghareeb, Bakhtyar Kamal Muhamed, Hemn Abdalla Omer

“…Fish, eggs and yogurt conception was common among those participants whom their serum vitamin D was adequate, in contrary, there were less consumed among those who had vitamin D deficiency.  …”
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Hubungan Umur dan Lamanya Hemodialisis dengan Status Gizi pada Penderita Penyakit Ginjal Kronik yang menjalani Hemodialisis di RS. Dr. M. Djamil Padang by Hannie Qalbina Syaiful, Fadil Oenzil, Rudy Afriant

“…Malnutrition is more common in CKD patients. A total of 40% malnutrition case is found in patients at the beginning of their hemodialysis. …”
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A novel multi-model estimation of phosphorus in coal and its ash using FTIR spectroscopy by Arya Vinod, Anup Krishna Prasad, Sameeksha Mishra, Bitan Purkait, Shailayee Mukherjee, Anubhav Shukla, Nirasindhu Desinayak, Bhabesh Chandra Sarkar, Atul Kumar Varma

“…X-ray fluorescence (XRF) is a commonly used analytical technique for the determination of phosphorus content in coal and coal ash samples but proves challenging due to their comparatively weak fluorescence intensity. …”
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Umbilical Cord Blood Bilirubin as a Predictor of Significant Hyperbilirubinemia Requiring Phototherapy among Full-term Healthy Neonates: A Prospective Study by Preethi B Patil, Prasanna Saka, Abhay K Chidananda

“…Early discharge of healthy-term newborns after delivery has become a common practice, which may be the cause for readmission during the early neonatal period. …”
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Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy by Mafalda Bacalhau, Filipa C. Ferreira, Marcelo Folhadella M. F. Azevedo, Talita P. Rosa, Camilla D. Buarque, Miquéias Lopes-Pacheco

“…<b>Conclusions:</b> Our data suggest that these new potentiators might share a common mechanism with apigenin, which is conceivably distinct from that of VX-770 and ABBV-3067. …”
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