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26581
Identification of novel autoantibodies in Sjögren’s disease
Published 2025-02-01“…Results45 novel autoantibodies were significantly (p ≤ 0.05) more prevalent in SjD than in HC and were detected in up to 19% of the SjD cohort. The most common autoantibodies were against CCL4, M5, TMPO and OAS3. …”
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26582
Intratumoural CD8+ CXCR5+ follicular cytotoxic T cells have prognostic value and are associated with CD19+ CD38+ B cells and tertiary lymphoid structures in colorectal cancer
Published 2024-12-01“…Abstract Background Colorectal cancer (CRC) is the most common digestive cancer in the world. Microsatellite stability (MSS) and microsatellite instability (MSI-high) are important molecular subtypes of CRC closely related to tumor occurrence and progression and immunotherapy efficacy. …”
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26583
Disrupting USP39 deubiquitinase function impairs the survival and migration of multiple myeloma cells through ZEB1 degradation
Published 2024-12-01“…Abstract Background Multiple Myeloma (MM) is the second most common hematological malignancy, characterized by the accumulation of monoclonal plasmocytes in the bone marrow. …”
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26584
Assessment of vitamin D status in obese and non-obese patients: A case-control study
Published 2025-01-01“…Conclusion: Vitamin D deficiency is common in obese patients, as highlighted by our study, which is in line with other findings. …”
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26585
Comprehensive prognosis assessment of cardiovascular magnetic resonance parametric mapping in light chain amyloidosis
Published 2025-01-01“…Conclusion: This study highlights that T2 is a valuable independent predictor of mortality in an AL amyloidosis population, additive to common CMR risk factors. Moreover, myocardial edema assessment identified patients in need of adjunctive therapies, which is of particular prognostic significance in patients with deep therapeutic response.…”
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26586
Regulatory signatures involved in the cell cycle pathway contribute to egg production heterosis in chicken
Published 2025-02-01“…By using weighted gene co-expression network analysis (WGCNA), we obtained multiple gene co-expression modules that were significantly correlated with egg number for each group. The common KEGG pathways including apelin signaling pathway, cell cycle, ribosome, spliceosome and oxidative phosphorylation, were screened for the 2 crossbreds. …”
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26587
Increasing prevalence of thyroid autoimmunity in childhood type 1 diabetes in the pre-COVID but not during the COVID era
Published 2025-01-01“…Among our children with TA, 28.5% exhibited clinically relevant thyroid-stimulating hormone (TSH) abnormalities (most commonly subclinical hypothyroidism) and/or were prescribed thyroid medication. …”
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26588
How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh?
Published 2025-02-01“…Additionally, the effects of two common environmental variables—solar radiation and mean annual temperature (MAT)—were significant (p < 0.05) predictors of AGTC at the landscape level but not at the site level. …”
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26589
Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation
Published 2025-02-01“…Abstract Background Hypertrophic scar (HS) is a common fibrotic skin disorder characterized by the excessive deposition of extracellular matrix (ECM). …”
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26590
Evaluation of the Prognostic Value of Red Cell Distribution Width to Total Serum Calcium Ratio in Patients with Acute Pancreatitis
Published 2021-01-01“…Acute pancreatitis (AP) is a sudden inflammatory process in the pancreas with variable involvement of nearby organs or other organ systems, and it is a common cause for hospitalization of gastrointestinal origin. …”
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26591
Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis)
Published 2025-01-01“…Furthermore, we identified a set of shared clonotypes across the samples, highlighting commonalities in the buffalo antibody repertoire.ConclusionThese findings contribute to the understanding of buffalo immune function and provide insights into the evolution and diversity of ruminant immunoglobulin genes.…”
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26592
Safety and Efficacy of Subcutaneous Rituximab in Previously Untreated Patients with CD20+ Diffuse Large B-Cell Lymphoma or Follicular Lymphoma: Results from an Italian Phase IIIb S...
Published 2022-01-01“…Neutropenia (14 patients, 8.9%) was the most common treatment-related TEAE. Two patients with DLBCL (2.8%) and 6 with FL (7.0%) discontinued rituximab due to TEAEs. 65.2% and 69.7% of patients with DLBCL and 67.9% and 73.6% of patients with FL had complete response (CR) and CR unconfirmed, respectively. …”
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26593
Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil
Published 2025-01-01“…IntroductionFollicular lymphoma (FL) is a common type of non-Hodgkin lymphoma that is incurable but often follows an indolent course. …”
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26594
Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation
Published 2025-01-01“…Abstract Background Hematopoietic stem cell transplantation (HSCT) is a common therapy for many hematologic malignancies. …”
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26595
Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation
Published 2025-01-01“…Co-expression module analysis identified module genes, which were intersected with HIF1A-related genes to identify common genes. Machine learning identified hub genes from intersection genes and PPI networks were constructed to explore relationships among hub and HIF1A. …”
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26596
Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study
Published 2025-01-01“…Unilateral segment hypoplasia (30%) and unilateral segment absence (29%) were the most common variations, with over 50% related to the posterior communicating artery (PComA). …”
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26597
Case report: Novel ACTN4 variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation
Published 2025-01-01“…BackgroundSteroid-resistant nephrotic syndrome (SRNS) is a rare kidney disease commonly characterized histopathologically by focal and segmental glomerulosclerosis (FSGS) or minimal change disease. …”
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26598
Bibliometric analysis of competency of specialist nurses based on CiteSpace (基于CiteSpace的专科护士胜任力的文献计量学分析)
Published 2022-12-01“…The bibliometric results showed that the common research hotspots of Chinese and foreign literatures were the influencing factors of specialist nurse competency, the evaluation index of specialist nurse competency and the training of specialist nurse competency. …”
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26599
Weight-based enoxaparin thromboprophylaxis in young trauma patients: analysis of the CLOTT-1 registry
Published 2024-07-01“…WB patients were younger, female, more severely injured, and underwent major operation or major venous repair at a higher rate than individuals in the SFD group. Obesity was more common among the SFD group. Unadjusted VTE rates were comparable (WB 3.1% vs. …”
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26600
The use of patient-generated health data in the management of low anterior resection syndrome: a qualitative study
Published 2024-12-01“…Most participants described finding it difficult to interpret the data and identified time constraints, legibility, and completeness as the most common barriers to reviewing data in clinic. In terms of perceived usefulness, data collection was felt to help clinicians understand symptoms and their impact and assist patients with self-management. …”
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