Drp1–associated genes implicated in sepsis survival by Marissa D. Pokharel, Marissa D. Pokharel, Anlin Feng, Anlin Feng, Ying Liang, Ying Liang, Wenli Ma, Wenli Ma, Saurabh Aggarwal, Hoshang Unwalla, Stephen M. Black, Stephen M. Black, Stephen M. Black, Ting Wang, Ting Wang, Ting Wang

“…Next, we compared genes of proteins that interact with Drp1 to sepsis survival genes and identified 7 common genes, establishing a GS we term as protein-protein interaction (PPI)-based GS. …”
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Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: pro... by Suzana Shahar, Kalavathy Ramasamy, Norhayati Ibrahim, Nur Nadia Mohamad Habibullah, Munirah Ismail, Mohd Zul Amin Kamaruddin, Shirley Gee Hoon Tang, Mohd Faisal Abdul Hamid

“…The study involves 198 adults aged 18–59 years with moderate stress levels as assessed using Perceived Stress Scale 10 (score 14–26) and Patient Health Questionnaire 9 (score ≥9); and had symptoms of common colds for the past 6 months as assessed using Jackson Cold Scale. …”
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Research priorities for autosomal dominant polycystic kidney disease: a UK priority setting partnership by Tess Harris, Albert Ong, Paul J D Winyard, Richard N Sandford, Maryrose Tarpey, Hannah R Bridges, Wendy D Brown, Natasha L O’Brien, Ann C Daly, Bharat K Jindal, Gillian S Mundy, Albert J Power, John Sayer, Roslyn J Simms, Patricia D Wilson

“…Objectives Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney condition, accounting for 7%–10% of patients with kidney failure. …”
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Distal Femur Type III Open Fractures: Functional Outcome Analysis by Arul R Bhagyaraj, Anand Ashok, Manisha J Kumar, Krupakaran Ganesan, Anand Kurian, Dan B Inja, Manasseh Nithyananth, Vinoo M Cherian, Jeremy Bliss

“…Introduction: The common goal of open distal femoral fracture management is the restoration of bone alignment, soft tissue management, rotation, length, and stable fixation of the fracture and early mobilization. …”
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Different surgical methods of hysterectomy for the management of endometrial cancer: a systematic review and network meta-analysis by Yuquan Yuan, Yuquan Yuan, Qin Tan, Yingfan Chen, Keyang Zhu, Bin Pan, Bao Liu, Bao Liu, Chunyan Ren, Chunyan Ren, Ganghui Li, Ganghui Li, Cheng Chen, Chengzhi Zhao, Chengzhi Zhao

“…The study aimed to assess the efficacy and safety of four common surgical methods of hysterectomy.MethodsWe systematically searched the PubMed, Cochrane Library databases, Medline, EMBASE and Web of Science from their inception until April 30, 2024. …”
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Relating Sensory, Cognitive, and Neural Factors to Older Persons’ Perceptions about Happiness: An Exploratory Study by Alexandra J. Horne, Kimberly S. Chiew, Jie Zhuang, Linda K. George, R. Alison Adcock, Guy G. Potter, Eleonora M. Lad, Scott W. Cousins, Frank R. Lin, Sara K. Mamo, Nan-Kuei Chen, Abigail J. Maciejewski, Xuan Duong Fernandez, Heather E. Whitson

“…In this exploratory study, we utilized an available dataset to investigate how aspects of health commonly deteriorating with age, including sensory (i.e., vision and hearing) and cognitive status, relate to variability in self-described contributors to happiness. …”
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Cluster randomised controlled trial to examine medical mask use as source control for people with respiratory illness by Abrar Ahmad Chughtai, Chandini Raina MacIntyre, Yi Zhang, Quanyi Wang, Bayzidur Rahman, Haiyan Zhang, Holly Seale, Daitao Zhang, Yanhui Chu

“…Rationale Medical masks are commonly used by sick individuals with influenza-like illness (ILI) to prevent spread of infections to others, but clinical efficacy data are absent.Objective Determine whether medical mask use by sick individuals with ILI protects well contacts from related respiratory infections.Setting 6 major hospitals in 2 districts of Beijing, China.Design Cluster randomised controlled trial.Participants 245 index cases with ILI.Intervention Index cases with ILI were randomly allocated to medical mask (n=123) and control arms (n=122). …”
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High Frequency of AIFM1 Variants and Phenotype Progression of Auditory Neuropathy in a Chinese Population by Hongyang Wang, Dan Bing, Jin Li, Linyi Xie, Fen Xiong, Lan Lan, Dayong Wang, Jing Guan, Qiuju Wang

“…In conclusion, we confirmed that AIFM1 is the primary related gene among late-onset AN cases, and the most common recurrent variant is p.Leu344Phe. Except for the X-linked recessive inheritance pattern, the X-linked dominant inheritance pattern is another probability of AIFM1-related AN, with females affected. …”
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Feasibility and Preliminary Effects of Acupuncture for Cognitive Dysfunction in Diverse Cancer Survivors: A Pilot, Randomized, Placebo-Controlled Trial by Xiaotong Li, Kaitlin Lampson, Tim A. Ahles, James C. Root, Q. Susan Li, Yuelin Li, Anam Ahsan, Jun J. Mao, Kevin T. Liou

“…Eleven mild adverse events were reported, with pain and bleeding at the needling sites being the most common. (4) Conclusions: The findings support the feasibility and safety of conducting a randomized, placebo-controlled trial to evaluate acupuncture for cognitive dysfunction in cancer survivors.…”
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Bronchiectasis Exacerbation Increases the Risk of Adverse Renal Outcomes—Results From a Large Territory‐Wide Cohort Study by Wang Chun Kwok, Chung Ki Tsui, Leung Sze Him Isaac, Chun Ka Emmanuel Wong, Terence Chi Chun Tam, James Chung Man Ho, Desmond Yat Hin Yap

“…Conclusions Renal progression and AKI are common among patients with bronchiectasis, and BE is an independent risk factor for adverse renal outcomes.…”
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Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions by Jun Song, Meiqi Li, Yuan Tao, Yumeng Li, Canrong Mai, Jingting Zhang, Lan Yao, Shaoquan Shi, Jianyong Xu

“…Abstract Background Intrauterine adhesions (IUA) is one of the most common gynecological diseases and main causes of uterine infertility. …”
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2′-Hydroxycinnamaldehyde induces ROS-mediated apoptosis in cancer cells by targeting PRX1 and PRX2 by Yae Jin Yoon, Yu-Jin Lee, Jiyeon Choi, Seung-Wook Chi, Sangku Lee, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han

“…2′-Hydroxycinnamaldehyde (HCA) is a component of the commonly used spice cinnamon, which has beneficial effects on cancer, allergies, bacterial/viral infections, and Alzheimer’s disease. …”
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Herbal HuoXueTongFu Formula with anti-inflammatory and fibrinolytic activity regulation for the prevention of postoperative peritoneal adhesions by Lili Yang, Lili Yang, Yali Wang, Yali Wang, Zhengjun Li, Zhengjun Li, Wen Li, Yanqi Chen, Ziyang Kong, Huixiang Zhang, Jiafei Wu, Mingqi Shang, Ming Li, Yaoyao Bian, Yaoyao Bian, Yaoyao Bian, Li Zeng, Li Zeng

“…The potential anti-fibrinolytic activity in the next stage of PPA formation was subsequently explored in PPA mice on Day 7 postsurgery.ResultsNetwork pharmacology revealed 160 common targets between HXTF and PPA. Several core targets, i.e., matrix metalloproteinase 9 (MMP9), tissue-type plasminogen activator (tPA), and plasminogen activator inhibitor 1 (PAI-1), were annotated as important biological processes (extracellular matrix disassembly and the collagen catabolic process). …”
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Spatiotemporal clustering of anthrax and molecular typing of Bacillus anthracis in Ningxia Hui Autonomous Region, 2019 – 2022 by Ran XIAN, Cong YANG, Jianwei GAO, Lei GAO, Qian CHEN, Yu ZHAO, Wenhe KUAI, Haohao FAN, Xiaodi LI, Jiangtao MA

“…The genetic relationships of the 14 B. anthracis strains isolated during the same period were defined as: A.Br 001/002 subgroup, 6 different MLVA genotypes within A3.b gene cluster, of which 3 common genotypes were defined as 2, 3, and 5 PHANA genotypes, respectively, by SNR-4 analysis; SNR-4 analysis showed 12 SNR genotypes. …”
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Emergency medicine pharmacists’ interventions in the tertiary hospitals’ emergency departments in Malaysia by Hock Peng Koh, Haliza Ab Jalal, Yee Ping Koo, Mary Siew Yng Chen, Manimegahlai Selvaratanam, Anaanthan Bhuvanendran Pillai, Wai Kit Wong, Xin Nee Guee, Sherene Su Ann Tan, Shirlyn Tan, Lih Jiuan Teh, Rosalind Guen Lin Sia

“…Insulin, enoxaparin, and noradrenaline were the most intervened HAMs.Conclusion: Inappropriate treatment regimens were the most common intervention category done by EM pharmacists in Malaysia. …”
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Sandpiper Optimization Algorithm With Region Growing Based Robust Retinal Blood Vessel Segmentation Approach by Ibrahim AlMohimeed, Mohamed Yacin Sikkandar, A. Mohanarathinam, Velmurugan Subbiah Parvathy, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

“…Retinal blood vessel examination is commonly utilized for retinal disease diagnosis by ophthalmologists. …”
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Evaluation of the merit of ethanolic extract of Annona reticulata as an anti-cancer agent in human colon cancer cell lines (HCT-116) [version 2; peer review: 2 approved, 1 not appr... by Sri Pragnya Cheruku, Krishnananda Prabhu, Akshatha G Nayak, Vijetha Shenoy Belle, Vanishree Rao, Pooja Prakash Rao, Nitesh Kumar

“…Background Colon cancer is the third most common cancer type worldwide. Novel alternative therapeutic anti-cancer drugs against colon cancer with less toxicity are to be explored . …”
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Addressing the gap in preterm resuscitation practices in high-income and low-middle income countries: a multicenter survey of the Asian neonatal network collaboration by Rinawati Rohsiswatmo, Rizalya Dewi, Jennie Sutantio, Zubair Amin, Young-Ah Youn, Sae Yun Kim, Su Jin Cho, Yun Sil Chang, Satoshi Kusuda, Fuyu Miyake, Tetsuya Isayama

“…Equipment availability during resuscitation was also variable; saturation monitors, radiant warmers, and plastic wraps were available in almost all hospitals, whereas oxygen and air blenders, heated humidified gas, and end-tidal CO2 detectors were more available in HICs. The most common device for Positive Pressure Ventilation (PPV) was the T-piece resuscitator (52.3%).ConclusionThe neonatal resuscitation practices for extremely preterm infants, encompassing staff, equipment, and guidelines, exhibited variance between HICs and LMICs in the AsianNeo region. …”
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Maize Herbivore-Induced Volatiles Enhance Xenobiotic Detoxification in Larvae of <i>Spodoptera frugiperda</i> and <i>S. litura</i> by Peng Wang, Qiyue Zeng, Yi Zhao, Xiaomin Sun, Yongqiang Han, Rensen Zeng, Yuanyuan Song, Dongmei Chen, Yibin Lin

“…Larval exposure of the invasive alien species <i>S. frugiperda</i> to maize HIPVs significantly enhanced their tolerance to all three of the well-known defensive compounds 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA), chlorogenic acid, and tannic acid in maize and the two commonly used insecticides methomyl and chlorpyrifos. …”
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Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS by Zhong‐Hua Lu, Yan Tang, Hu Chen, Feng Liu, Mei Liu, Lu Fu, Xian‐Kai Wang, Ming‐Juan Li, Wei‐Li Yu, Yun Sun

“…ABSTRACT Background Sepsis and acute respiratory distress syndrome (ARDS) are common inflammatory conditions in intensive care, with ARDS significantly increasing mortality in septic patients. …”
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