Plasma Metabolite Profiles of Healthy Volunteers after Administration of a Thai Herbal Formula for Dizziness by Ranida Boonrak, Kajee Pilakasiri, Suksalin Boonranasubkajorn, Natchagorn Lumlerdkij, Pravit Akarasereenont

“…No direct impact on sleep-related metabolites was found, the anti-inflammatory effects suggested by YHF20 could indirectly improve sleep quality by mitigating inflammation, a common sleep disruptor. These results highlight YHF20's potential for enhancing life quality through anti-inflammatory mechanisms. …”
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Nonhomogeneous Markov chains for degeneration behaviour of RC members’ durability and its Bayesian updating by Ruiqi Guo, Dengguo Li, Guoxin Chen, Yu Jin, Hui Li, Yuanpeng Zhang

“…The results indicate that the updated model predictions envelop both the predictions from the prior model and the actual state assessment results, effectively integrating common understanding with individualized information.…”
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Factors influencing image quality in Tibetan children by optical coherence tomography by Yao Yao, Jiawen Liu, Lei Li, Weiwei Chen, Zhaojun Meng, Jing Fu

“…After manual screening, 1,447 (78%) and 1,289 (70%) images could be analyzed in the macular and optic disc regions, respectively. Common image flaws were blinking or fixation error (70%+), poor focusing, and positioning errors. …”
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Autoantibodies in type 1 diabetes: Prevalence and clinical profiles by Raja Hazime, Saad Lamjadli, Morad Guennouni, Mounir Belkrachni, Fatima-Ezzohra Eddehbi, Ider Oujamaa, Lahcen Elmoumou, Aicha Bourrahouate, Imane Ait Sab, Hicham Baizri, Nawal El Ansari, Brahim Admou

“…Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases in children and is associated with acute and serious chronic complications. …”
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The Influence of Various Morphologic and Hemodynamic Carotid Plaque Characteristics on Neurological Events Onset and Deaths by Milan D. Brajovic, Nataša Markovic, Goran Loncar, Nikola Šekularac, Dejan Kordic, Nebojša Despotovic, Predrag Erceg, Branislav Donfrid, Zvezdan Stefanovic, Milica Bajcetic, Ljiljana Brajovic, Živorad Savic

“…In the SCS group, a significantly higher frequency of increased peak systolic and end diastolic velocities was noted at the beginning and end of the study (both p < 0.01), as well as for contralateral common (CCA) or internal carotid artery (ICA) occlusion (p < 0.05 and p < 0.01, respectively), but reduced carotid blood flow volume (p < 0.05) only at the end of the study. …”
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Cohort profile: maternal and child health and parenting practices during the COVID-19 pandemic in Ceará, Brazil: birth cohort study (Iracema-COVID) by Marcia C Castro, Márcia Maria Tavares Machado, Simone Farías-Antúnez, David Augusto Batista Sá Araújo, Ana Luiza Penna, Francisco Ariclene Oliveira, Camila Machado de Aquino, Antônio Silva Lima Neto, Geziel dos Santos de Sousa

“…The prevalence of maternal common mental disorder symptoms was 32.5% (95% CI 27.8 to 37.6).Future plans Follow-up visits are planned to occur every 6 months for the next five years (2021–2025). …”
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Estimates of critical loads and exceedances of acidity and nutrient nitrogen for mineral soils in Canada for 2014–2016 average annual sulfur and nitrogen atmospheric deposition by H. Cathcart, J. Aherne, M. D. Moran, M. D. Moran, V. Savic-Jovcic, P. A. Makar, A. Cole

“…Parameterisation of the model for Canadian ecosystems was considered with attention to the selection of the chemical criterion for damage at a site-specific resolution, with comparison between protection levels of 5 % and 20 % growth reduction (approximating commonly chosen base-cation-to-aluminum ratios of 1 and 10, respectively). …”
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Association of FMO3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study by Tyler S. Bryant, Priya Duggal, Bing Yu, Alanna C. Morrison, Tariq Shafi, Georg Ehret, Nora Franceschini, Eric Boerwinkle, Josef Coresh, Adrienne Tin

“…Studies have reported conflicting results of the association of a common nonsynonymous variant, E158K (rs2266782), with hypertension. …”
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Environmental DNA metabarcoding shows potential for monitoring meiofauna and marine nematodes diversity in mangrove ecosystems in China by Mingcheng Hu, Yuqing Guo, Fenfen Ji, Yijia Shih, Kai Liu, Xiangxiang Yi, Yuanxin Fan

“…Daptonema and Terschellingia were common in both methods. In terms of abundance via eDNA metabarcoding, Daptonema had the highest relative abundance (85.71%), followed by Neochromadora (7.59%). …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…The DNA, which is free in the extracellular space, is commonly known as Cell-Free DNA (cfDNA). In healthy people, the levels of cfDNA in the circulation are notably minimal. …”
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Duodenal obstruction due to two congenital bands: a case report and literature review by Shiqiu Xiong, Kuku Ge, Chongzhi Hou, Hongbin Yang, Hanhua Zhang, Sheng Zhang, Bailing Liu, Yuewen Hao, Ying Fang, Xiaoxia Ren

“…The bands were resected, and gastroduodenoscopy confirmed the resolution of the obstruction.DiscussionWe reviewed 93 cases of anomalous congenital bands, including the present one, comprising 33 adults and 60 children, with 71.0% of the cases involving males. Common symptoms included vomiting and abdominal pain, with physical examinations often showing tenderness and distension. …”
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Superstition in Surgery: A Population-Based Cohort Study to Assess the Association Between Surgery on Friday the 13th and Postoperative Outcomes by Sanjana Ranganathan, MBE, Carlos Riveros, MD, Michael Geng, BS, Courtney Chang, MD, Yusuke Tsugawa, MD, MPH, PhD, Bheeshma Ravi, MD, PhD, Zachary Melchiode, MD, Siqi Hu, MD, PhD, Kathleen Kobashi, MD, MBA, Brian J. Miles, MD, Zachary Klaassen, MD, MSc, Avery Nathens, MD, MPH, PhD, Natalie Coburn, MD, MPH, Allan S. Detsky, MD, PhD, CM, Angela Jerath, MD, MSc, FRCPC, FANZCA, Christopher J. D. Wallis, MD, PhD, FRCSC, Raj Satkunasivam, MD, MS

“…A retrospective, population-based cohort study of 19,747 adults undergoing 1 of 25 common surgical procedures on Friday the 13th or flanking control Fridays (Friday the 6th and Friday the 20th) between January 1, 2007, and December 31, 2019, with 1 year of follow-up. …”
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Deep application of controlled-release urea increases the yield and saponin content of Panax notoginseng by regulating soil nitrate distribution by Yun-xia Su, Yun-xia Su, Yun-xia Su, Ping Zhao, Li-jie Jia, Li-jie Jia, Li-jie Jia, Yuan-feng Cao, Guan-ze Liu, Guan-ze Liu, Jun-wen Chen, Jun-wen Chen, Sheng-chao Yang, Sheng-chao Yang, Yan-li Zhou, Guang-qiang Long, Guang-qiang Long, Guang-qiang Long

“…However, its effects on P. notoginseng yield and quality, a medicinal plant with a prolonged nutrient acquisition duration, remain unclear.MethodsIn this study, we conducted a two-year field plot experiment to investigate the effect of CRU on P. notoginseng with three placement depths (0, 6, and 12 cm denoted as R0, R6, and R12, respectively) at an application dosage of 250 kg N ha-1 with biochar addition (R6B) and 20% N reduction (R6R) based on the R6, with conventional fertilization (250 kg N ha-1, common urea) serving as the control (CK).ResultsOur results indicated that yields increased by 27.1–37.6% with R0, R6, R12, and R6B, while remaining stable with R6R compared to CK. …”
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Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis by Xiaoling Zeng, Yuan Liao, Dan Huang, Jing Yang, Zhihua Dai, Zhengyong Chen, Xin Luo, Han Gong, Shengwen Huang, Leisheng Zhang

“…Abstract Previous cesarean scar defect (PCSD), also acknowledged as the myometrium of uterus defects, which commonly results in myometrial discontinuity between the uterine and cervical cavity. …”
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Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers by Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Ariela Victoria Borgmann, Isabela Dombeck Floriani, Marina Rachid Barreto, Tania Zaleski, Fabianne Altruda de Moraes Costa Carlesse, Giovanni Luís Breda, Fábio de Araújo Motta, Diego Rodrigues Falci, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Talita Teles Teixeira Pereira, João Luiz Baú-Carneiro, Flávio Queiroz-Telles

“…In children, the most common were fever (64.7%), tremors/chills (50%), and skin rash/itching (17.6%). …”
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Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study by Xiaohua Hu, Xianwu Ye, Haimin Chen, Bibo Wu, Qi Guo, Chen Yu, Wei Ding, Jianying Niu, Junli Zhao, Hualin Qi, Suhua Zhang, Cheng Xue, Liming Zhang

“…Abstract Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. Despite the prevalence of these conditions, the interrelationships among them remain poorly understood in HD patients. …”
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Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study by Seda Kahraman, Mutlu Hizal, Burcin Cakan Demirel, Deniz Can Guven, Ozge Gumusay, Basak Oyan Uluc, Ertugrul Bayram, Burcu Gulbagci, Alper Yasar, Sena Ece Davarci, Eda Eylemer Mocan, Omer Acar, Deniz Isik, Esra Aydin, Yusuf Karakas, Melike Ozcelik, Murat Keser, Sadi Kerem Okutur, Onder Eren, Serkan Menekse, Dincer Aydin, Funda Yilmaz, Ozlem Dogan, Gulhan Ozkanli, Hakan Yucel, Veli Sunar, Musa Baris Aykan, Ozlem Ozdemir, Berna Bozkurt Duman, Merve Keskinkilic, Teoman Sakalar, Ali Inal, Muge Karaoglanoglu, Asude Aksoy, Muhammed Muhiddin Er, Nazim Serdar Turhal, Nurhan Onal Kalkan, Mehmet Ali Nahit Sendur

“…Grade 3–4 AEs were reported in 42.7% for the entire group, and neutropenia was the most common (37.3%). It can be concluded that combination therapy with palbociclib or ribociclib with an ET partner has similar efficacy and is safe among subgroups of older patients diagnosed with HR+/HER2-MBC.…”
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Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK by Tim Doran, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Siobhan Reilly, Claire Planner, Ivan Olier, Linda Gask

“…We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. …”
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The age-adjusted international prognostic index 2 (A-FLIPI2) for elderly patients with follicular lymphoma by Jiesong Wang, Junlei Jia, Jingwei Yu, Jing Liu, Meng Gao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Bin Meng, Wenchen Gong, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…Follicular lymphoma (FL) is a common B-cell lymphoma and typically affects the elderly population. …”
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Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3 by Majd B. Protty, Victoria J. Tyrrell, Ali A. Hajeyah, Bethan Morgan, Daniela Costa, Yong Li, Anirban Choudhury, Rito Mitra, David Bosanquet, Alex Reed, Iuliia K. Denisenko, Katsuyuki Nagata, Hideo Shindou, Benjamin F. Cravatt, Alastair W. Poole, Takao Shimizu, Zaheer Yousef, Peter W. Collins, Valerie B. O’Donnell

“…EoxPL are altered in ASCVD by a commonly used cardiovascular therapy, and LPCAT3 was identified as the acyltransferase generating aspirin-sensitive 12-LOX diacyl forms. …”
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