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  1. 25161

    Immune checkpoint inhibitors in cancer patients with autoimmune disease: Safety and efficacy by Jiayuan Le, Yuming Sun, Guangtong Deng, Yating Dian, Yanli Xie, Furong Zeng

    Published 2025-12-01
    “…During ICIs treatment, irAEs are common among cancer patients with autoimmune diseases, but severe irAEs is relatively low. …”
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  2. 25162

    Sexual and Gender Minority Adolescents’ Preferences for HIV Pre-Exposure Prophylaxis Social Marketing Campaigns: Qualitative Preimplementation Study by Kathryn Macapagal, Juan Pablo Zapata, Junye Ma, Jacob D Gordon, Christopher Owens, Silvia Valadez-Tapia, Peter Cummings, Nathan Walter, Jim Pickett

    Published 2025-01-01
    “…ConclusionsThese findings lay the groundwork for designing adolescent-centered educational PrEP campaigns that prioritize both user preferences in PrEP marketing design and strategies to overcome common barriers to PrEP awareness.…”
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  3. 25163

    Changes of CA19-9 levels and related influencing factors in patients with type 2 diabetes mellitus after antidiabetic therapy by Xiafei Zhao, Yan Wang, Ling Zhou, Aili Ye, Quanfeng Zhu

    Published 2025-01-01
    “…Abstract Abnormalities of carbohydrate antigen 19 − 9 (CA19-9) are common in patients with type 2 diabetes mellitus (T2DM), and in some patients, CA19-9 returns to normal level after glycemic control. …”
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  4. 25164

    Chlamydia cases in women of reproductive age, 2006–2020: an analysis of surveillance data from Southern China by Peizhen Zhao, Peng Liang, Jinshen Wang, Wenqian Xu, Shujie Huang, Cheng Wang

    Published 2025-01-01
    “…Abstract Background Chlamydia is common among women of reproductive age and can cause serious health issues. …”
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  5. 25165

    Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review by Ayden I Scheim, Dan Werb, Nazlee Maghsoudi, Zack Marshall, Siobhan Churchill, Carolyn Ziegler

    Published 2020-09-01
    “…Most (n=104, 91.2%) were from the USA, evaluated cannabis reform (n=109, 95.6%) and focussed on legal regulation (n=96, 84.2%). 224 study outcome measures were categorised into 32 metrics, most commonly prevalence (39.5% of studies), frequency (14.0%) or perceived harmfulness (10.5%) of use of the decriminalised or regulated drug; or use of tobacco, alcohol or other drugs (12.3%). …”
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  6. 25166

    Effect of Proparacaine 0.375%-Sodium Fluorescein 0.25% Eye Drop Mixture and Fluorescein Strip on Anterior Segment Parameters by Mustafa Doğan, Mehmet Cem Sabaner, Mehmet Akif Erol

    Published 2018-01-01
    “…To determine the effect of proparacaine 0.375%-sodium fluorescein 0.25% eye drop mixture and fluorescein strip on anterior segment parameters commonly used in routine ophthalmology practice. Methods. 115 healthy volunteers without any systemic or ocular disease were divided into two groups. 57 volunteers were in the proparacaine 0.375%-sodium fluorescein 0.25% eye drop mixture group, and 58 volunteers were in the fluorescein strip group. …”
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  7. 25167

    Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021 by Yanyu Zhang, Quanxin Su, Jiawen Yu, Xiuli Sun

    Published 2025-02-01
    “…PurposeMultiple myeloma (MM) is a hematologic malignancy originating from plasma cells with clinical manifestations such as hypercalcemia, cytopenias (most commonly anemia) and renal failure. Here, we analyzed the disease burden and changing trends of MM in China from 1990 to 2021, aiming to provide a scientific and effective basis for the prevention and control of MM disease in China.MethodsWe extracted MM related data from the Global Burden of Diseases (GBD) 2021 database from 1990 to 2021. …”
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  8. 25168

    Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking by Charlotte Waddell, Christine Schwartz, Jenny Lou Barican, Donna Yung, Yufei Zheng, Katholiki Georgiades

    Published 2022-02-01
    “…Anxiety (5.2%), attention-deficit/hyperactivity (3.7%), oppositional defiant (3.3%), substance use (2.3%), conduct (1.3%) and depressive (1.3%) disorders were the most common. Among children with mental disorders, only 44.2% (95% CI 37.6% to 50.9%) received any services for these conditions.Conclusions An estimated one in eight children have mental disorders at any given time, causing symptoms and impairment, therefore requiring treatment. …”
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  9. 25169

    The Systemic Effects of Blood Flow Restriction Training: A Systematic Review by Bradley C Miller, Alexander W Tirko, Justin M Shipe, Olivia R Sumeriski, Kelley Moran

    Published 2021-08-01
    “…PEDro scores ranged between 4 and 8, and had CEBM levels of evidence of 1 and 2. Common systems studied included cardiovascular, musculoskeletal, endocrine, and psychosocial. …”
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  10. 25170

    The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

    Published 2025-01-01
    “…Aim In this study, we analyzed expression profile datasets and miRNA expression profiles related to HCC from the GEO using R software to detect differentially expressed genes (DEGs) and differentially expressed miRNAs (DEmiRs). Methods and results Common DEGs were identified, and a PPI network was constructed using the STRING database and Cytoscape software to identify hub genes. …”
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  11. 25171

    Risk of pneumonia in patients with isolated minor rib fractures: a nationwide cohort study by Yu-Hsun Wang, Ming-Chih Chou, Sai-Wai Ho, Ying-Hock Teng, Shun-Fa Yang, Han-Wei Yeh, Chao-Bin Yeh

    Published 2017-01-01
    “…Objectives Isolated minor rib fractures (IMRFs) after blunt chest traumas are commonly observed in emergency departments. However, the relationship between IMRFs and subsequent pneumonia remains controversial. …”
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  12. 25172
  13. 25173

    Inhibition and evasion of neutrophil microbicidal responses by Legionella longbeachae by Hannah E. Hanford, Christopher T. D. Price, Silvia Uriarte, Yousef Abu Kwaik

    Published 2025-02-01
    “…Collectively, we conclude that L. longbeachae evades restriction by human neutrophils via T4SS-independent mechanisms and utilizes trans-acting T4SS-dependent mechanisms for inhibition of neutrophil ROS generation throughout the cell cytosol.IMPORTANCELegionella longbeachae is commonly found in soil environments where it interacts with a wide variety of protist hosts and microbial competitors. …”
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  14. 25174

    Toxicity, antifeedant and repellent activities of five essential oils on adult Cassida vittata Vill. (Coleoptera: Chrysomelidae) by Achraf Charkaoui, Rachid Jbilou, Houssam Annaz, Kacem Rharrabe

    Published 2024-12-01
    “…Chemical pesticides are considered the most common strategy to control this pest, and their use is extremely harmful to human health and the environment. …”
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  15. 25175

    The Role of Microelements of Lumbar Disc Degeneration in Patients Undergoing Lumbar Spine Surgery by Sadiq R. Karkush, Manal K. Rasheed, Ali T. Abdul Wahid, Ahmed R. Majeed

    Published 2024-12-01
    “… Background: Lumbar disc degeneration (LDD) is a common musculoskeletal disorder that frequently causes low back pain (LBP). …”
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  16. 25176

    Gender characteristics, social determinants, and seasonal patterns of malaria incidence, relapse, and mortality in Sistan and Baluchistan province and other province of Iran: A sys... by Maryam Khazaee-Pool, Mahmood Moosazadeh, Mehran Asadi-Aliabadi, Fereshteh Yazdani, Koen Ponnet

    Published 2025-02-01
    “…In term of socio-demographic status, malaria was more common in rural areas (82%). Although 28% were employed, and in term of age, young and old individuals (15 to 50 years) had the highest rate of infection. …”
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  17. 25177

    Identification of deleterious variants associated with male infertility genes in a cohort of idiopathic hypospermatogenesis patients by Nisha Sharma, Ashutosh Halder, Seema Kaushal, Manoj Kumar, Manish Jain

    Published 2025-01-01
    “…IntroductionHypospermatogenesis is a common histopathological subtype of non-obstructive azoospermia and is characterized by a decrease in the total number of germ cells within the seminiferous tubule as a result of spermatogenic failure. …”
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