Identification and Quality Evaluation of Raw and Processed Asarum Species Using Microscopy, DNA Barcoding, and Gas Chromatography-Mass Spectrometry by Guangzhe Yao, Wenjuan Ma, Xuhua Huang, Qi Jia, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He

“…Asarum (Aristolochiaceae) is one of the common herbs used to relieve exterior syndromes. Some volatile components of Asarum which have toxic effect may cause adverse reactions such as headache, general tension, unconsciousness, and respiratory paralysis. …”
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Analysis of Circulating Plasma MicroRNA Profile in Low-Grade and High-Grade Glioma – A Cross-Sectional Study [version 1; peer review: 2 approved, 1 approved with reservations, 1 no... by Sekar Safitri, Rachmat Andi Hartanto, Rusdy Ghazali Malueka, Bo Sun, Ery Kus Dwianingsih, Kusumo Dananjoyo, Ahmad Asmedi, Endro Basuki, Christina Megawimanti Sianipar, Yeshua Putra Krisnugraha

“…Background Glioma is the second most common type of brain tumor, accounting for 24% of all brain tumor cases. …”
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Constant Dizziness Versus Episodic Vertigo in Ménière’s Disease: Health-Related Quality of Life, Cognitive Dissonance, and Postural Problems by Ilmari Pyykkö, Jing Zou, Vinaya Manchaiah

“…The impact of balance problem was more severe among those with constant dizziness. The most common balance problem was tripping-off (34%), followed by swaying (25%) or rocking (8%) sensations. …”
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Carboplatin in combination with etoposide for advanced small cell lung cancer complicated with idiopathic interstitial pneumonia: a single-arm phase II study by Masaru Matsumoto, Yuji Minegishi, Katsuyuki Higa, Aya Fukuizumi, Naomi Onda, Susumu Takeuchi, Akihiko Miyanaga, Akihiko Gemma, Masahiro Seike

“…Abstract Background Acute exacerbation (AEx) of interstitial pneumonia is the most common lethal adverse event related to the pharmacological treatment of patients with lung cancer complicated with interstitial pneumonia. …”
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Chromosomal Abnormalities in Miscarriages and Maternal Age: New Insights from the Study of 7118 Cases by Anna A. Pendina, Mikhail I. Krapivin, Olga G. Chiryaeva, Lubov’ I. Petrova, Elizaveta P. Pashkova, Arina V. Golubeva, Andrei V. Tikhonov, Alla S. Koltsova, Ekaterina D. Trusova, Dmitrii A. Staroverov, Andrey S. Glotov, Olesya N. Bespalova, Olga A. Efimova

“…Chromosomal abnormalities of the embryo are the most common cause of first-trimester pregnancy loss. In this single-center study, we assessed the frequency and the spectrum of chromosomal abnormalities in miscarriages for each year of maternal age from 23 to 44. …”
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Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival by Laura F. Mortan, Laura F. Mortan, Brooke A. Meelheim, Justin Garland, Justin Garland, Jacqueline A. Bohn, Zitha Redempta Isingizwe, Doris M. Benbrook, Doris M. Benbrook

“…Background/ObjectivesPatients with ovarian cancer commonly experience metastases and recurrences, which contribute to high mortality. …”
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Predicting the exposure of mycophenolic acid in children with autoimmune diseases using a limited sampling strategy: A retrospective study by Ping Zheng, Ting Pan, Ya Gao, Juan Chen, Liren Li, Yan Chen, Dandan Fang, Xuechun Li, Fei Gao, Yilei Li

“…Abstract Mycophenolic acid (MPA) is commonly used to treat autoimmune diseases in children, and therapeutic drug monitoring is recommended to ensure adequate drug exposure. …”
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Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep... by Fei Chen, Jinghe Lang, Peter Hillemanns, Youzhong Zhang, Zoltán Novák, Long Sui, Ling Han, Christian Dannecker, Ctirad Mokráš, Zhixue You

“…Introduction High-risk human papilloma virus (HPV)-associated cervical cancer is the fourth most common cancer in women worldwide. Current treatments of high-grade squamous intraepithelial lesion (HSIL) of the cervix are based on invasive surgical interventions, compromising cervical competence and functionality. …”
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Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38−/− Mice by Qi Li, Chenyi Wu, Zhenlong Liu, Huiqing Zhang, Yuna Du, Yuxiang Liu, Kuangyu Song, Qiaofa Shi, Rong Li

“…Acute kidney injury (AKI), a common complication of Gram-negative bacterial sepsis, is caused by Toll-like receptor 4 (TLR4) activation. …”
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Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France by Huamao Mark Lin, Keith L. Davis, James A. Kaye, Katarina Luptakova, Saurabh P. Nagar, Mohamad Mohty

“…Lenalidomide-based regimens were most common (>50%) in second line. Hospitalization incidence in high risk patients was approximately twice that of standard risk patients. …”
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Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy by Qianqian Yan, Zihao Zhao, Dongwei Liu, Jia Li, Shaokang Pan, Jiayu Duan, Zhangsuo Liu

“…Our findings offer insights into the shared immune mechanisms of IgAN and IBD. These common pathways, diagnostic cross-talk genes, and cell-mediated abnormal immunity may inform further experimental studies.…”
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Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration by Aurélie Fessard, Aliki Zavoriti, Natacha Boyer, Jules Guillemaud, Masoud Rahmati, Peggy Del Carmine, Christelle Gobet, Bénédicte Chazaud, Julien Gondin

“…Methods Contractile activity was generated by applying repeated electrical stimuli over the mouse plantar flexor muscles. This method is commonly referred to as NeuroMuscular Electrical Simulation (NMES) in Human. …”
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Environment-friendly Ca2+/Cr3+ co-doping LaAlO3 ceramics with excellent infrared radiation performance for energy-saving by Xinglai Yuan, Qinghu Wang, Runke Wu, Shaobai Sang, Yibiao Xu, Xiong Liang, Liping Pan, Bingbing Fan, Yawei Li, Rui Zhang, Jiangtao Li, Olena Volkova

“…However, Cr6+ formation commonly occurs in materials and poses environmental and health risks, such as Cr6+ dissolution in water and CrO3(g) volatilization. …”
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A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes by Elizabeth Rendina-Ruedy, Kelsey D. Hembree, Angela Sasaki, McKale R. Davis, Stan A. Lightfoot, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith

“…This study investigated the long-term metabolic and skeletal consequences of two commonly used C57BL/6 substrains to a high fat (HF) diet. …”
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Instability of revised Korean Developmental Screening Test classification in first year of life by Ji Eun Jeong, You Min Kim, Na Won Lee, Gyeong Nam Kim, Jisuk Bae, Jin Kyung Kim

“…Seven infants (10.1%) scored below -2 SD in at least one domain, most commonly in gross and fine motor domains (7.3%). At 10–12 months, over 70% of infants scored in the ≥-1 SD group, except in the language domain. …”
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Instruments for assessing patient-reported experience measures among patients with diabetes mellitus: a scoping review by Soe Sandi Tint, Myo Zin Oo, Nida Buawangpong, Wichuda Jiraporncharoen, Nutchar Wiwatkunupakarn, Kittipan Rerkasem, Kanokwan Kulprachakarn, Hataichanok Chuljerm, Timothy E. O’Brien, Rohini Mathur, Chaisiri Angkurawaranon

“…Content analysis revealed five commonly measured domains: (1) care planning, (2) patient education, (3) professionalism, (4) quality of care, and (5) hospital care and transition, reflecting diverse patient experiences across healthcare services. …”
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Preservation of cellular structure via immersion fixation in brain banking by Macy Garrood, Emma L. Thorn, Adam Goldstein, Allison Sowa, William Janssen, Alyssa Wilson, Claudia S. López, Raakhee Shankar, Erin S. Stempinski, Kurt Farrell, John F. Crary, Andrew T. McKenzie

“… Immersing the brain in a solution containing formaldehyde is a commonly used method for preserving the structure of human brain tissue in brain banking. …”
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Optimising fatigue, abdominal pain and faecal incontinence in people with inflammatory bowel disease (IBD-BOOST Optimise): feasibility study of a checklist and algorithm for initia... by Thomas Hamborg, John McLaughlin, Ailsa Hart, Christine Norton, Sonia Bouri, Laura Miller, Jean-Frédéric LeBlanc, Asma Fikree, Imogen Stagg, Fionn Cléirigh Büttner

“…It is unknown how many have potentially reversible medical issues underlying these symptoms.Methods We conducted a study testing the feasibility of a patient-reported symptom checklist and nurse-administered management algorithm (‘Optimise’) to manage common medical causes of IBD-related fatigue, pain and faecal incontinence. …”
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Efficacy and safety of trabeculectomy versus peripheral iridectomy plus goniotomy in advanced primary angle-closure glaucoma: study protocol for a multicentre, non-inferiority, ran... by Keith Barton, Tin Aung, Ling Jin, Ping Lu, Xiulan Zhang, Robert N Weinreb, Yi Zhang, Li Tang, Guangxian Tang, Hengli Zhang, Aiguo Lv, Huiping Yuan, Yunhe Song, Fengbin Lin, DENNIS S C LAM, Lin Xie, Kun Hu, Xiaohong Liang, Yingzhe Zhang, Wulian Song, Xiaomin Zhu, Xinbo Gao, Sujie Fan, Yuying Peng, Mengfei Liao, Xin Nie, Ki-Ho Park

“…Minimally invasive glaucoma surgery (MIGS) plays an increasing role in the management of glaucoma due to its safer and faster recovery profile; cataract surgery-based MIGS is the most commonly performed such procedure in PACG. However, for patients with a transparent lens or no indications for cataract extraction, incorporation of MIGS into PACG treatment has not yet been reported. …”
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Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom by Sanjib Kumar Sharma, Emilie Alirol, Anup Ghimire, Suman Shrestha, Rupesh Jha, Surya B. Parajuli, Deekshya Shrestha, Surya Jyoti Shrestha, Amir Bista, David Warrell, Ulrich Kuch, Francois Chappuis, Walter Robert John Taylor

“…Of the 8 (5.1%) deaths, three occurred in transit to hospital. Severe ARA was common and recurrent and had overlapping signs with severe neurotoxic envenoming. …”
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