Integrating biomarkers for hemostatic disorders into computational models of blood clot formation: A systematic review by Mohamad Al Bannoud, Tiago Dias Martins, Silmara Aparecida de Lima Montalvão, Joyce Maria Annichino-Bizzacchi, Rubens Maciel Filho, Maria Regina Wolf Maciel

“…Results indicate that commonly used biomarkers such as D-dimer, PT, and APTT are rarely and superficially integrated into computational blood coagulation models. …”
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Comparison of Effect Sevoflurane-Based Anesthesia and Propofol-Based Anesthesia on the Early Postoperative Renal Function of Living Kidney Transplant Donors: A Randomized Controlle... by Cai J, Kang F, Han M, Huang X, Yan W, Wan F, Li J

“…Jianyue Cai,1,* Fang Kang,1,* Mingming Han,1 Xiang Huang,1 Wenlong Yan,1 Fuzhen Wan,2,3 Juan Li1 1Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People’s Republic of China; 2Department of Gastrointestinal Surgery, The second Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 3Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia*These authors contributed equally to this workCorrespondence: Juan Li, Administrative Director, Department of Anesthesia, First Affiliated Hospital of the University of Science and Technology of China, Tel +8613956005465, Email huamuzi1999@163.comPurpose: Living kidney transplantation is a common treatment for end-stage renal disease. The impact of anaesthetics on postoperative biomarkers of renal injury in living kidney transplant donors is not well understood.Patients and Methods: 70 transplant donors who underwent kidney extraction were randomly assigned to following two groups: sevoflurane (S group) and propofol (P group). …”
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Unanchored simulated treatment comparison on survival outcomes using parametric and Royston-Parmar models with application to lenvatinib plus pembrolizumab in renal cell carcinoma by Christopher G. Fawsitt, Janice Pan, Philip Orishaba, Christopher H. Jackson, Howard Thom

“…Matching-Adjusted Indirect Comparison (MAIC) is commonly used but does not account for violation of proportional hazards or enable extrapolations of survival. …”
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No association of ABO blood groups and Rh factor with primary liver cancer in cirrhotic patients: a single-center cross-sectional study by Liyan Dong, Liyan Dong, Yuhang Yin, Yuhang Yin, Huiyuan Lu, Huiyuan Lu, Di Sun, Di Sun, Dongyang Wang, Deli Zou, Xingshun Qi

“…BackgroundPrimary liver cancer (PLC) is one of the most common cancers worldwide. ABO blood groups and rhesus (Rh) factor are inherited characteristics. …”
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Effectiveness of Cognitive Behavioral Therapy Provided Through a Web Application for Subthreshold Depression, Subthreshold Insomnia, and Subthreshold Panic: Open-Labeled 6-Arm Rand... by Kayoko Taguchi, Mirai Miyoshi, Yoichi Seki, Shiori Baba, Eiji Shimizu

“… BackgroundA common definition of “subthreshold” is that the diagnostic threshold is not met but the individuals are not asymptomatic. …”
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Comparison of Individualized Rescue Luteal Phase Support Strategies with Vaginal and Combined Vaginal & Subcutaneous Progesterone Administration in Artificial Frozen-Thawed Blastoc... by Secil Irem Arik Alpcetin, Onur Ince, Bengisu Akcay, Munire Funda Cevher Akdulum, Erhan Demirdag, Ahmet Erdem, Ahmet Erdem, Mehmet Erdem, Mehmet Erdem

“…ObjectivesHormone replacement therapy (HRT) frozen embryo transfer (FET) cycles are common in assisted reproductive techniques. As the corpus luteum is absent in these cycles, luteal phase support is provided by administering progesterone (P4) through transvaginal, parenteral, or oral routes. …”
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Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice by Shaymaa M. Eissa, Asmaa M. Mahfouz, Saad M. El-Gendy, Al-shimaa Zakaria, Heba Effat, Hanan R. H. Mohamed

“…Therefore, this study evaluated HAP-NPs' antitumoral activity in Ehrlich solid carcinoma (ESC)-bearing mice, in addition, we examined the anticancer efficacy of combined treatment of a common chemotherapeutic drug such as Cisplatin (CDDP) and HAP-NPs in ESC-bearing mice. …”
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Designing a Stock Recommender System Using the Collaborative Filtering Algorithm for the Tehran Stock Exchange by Marziyeh Nourahmadi, Ali Rahimi, Hojjatollah Sadeqi

“…In this research, assuming the existence of the transmission effect on the Tehran Stock Exchange, we used the collaborative filtering technique, a common algorithm in recommender systems, to design a stock recommender system. …”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…ABSTRACT Pleural infections are common and associated with substantial healthcare costs, morbidity, and mortality. …”
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La tranchée supérieure de l’aqueduc du Gier à Saint-Joseph (Loire) : nouvelles données et synthèse by Kilian Blanc, Guillaume Maza

“…In these, a number of hypotheses had been proposed as to its nature and function, the most commonly accepted being that it represented an early route of the Gier aqueduct which was abandoned because the work involved in developing it in the large valleys that it bypasses would have been too extensive and costly.The 2008 excavation that followed this evaluation, led by Guillaume Maza (Evéha), focused only the upper trench, its immediate surroundings and an ancient ground level section observed to the northeast of it. …”
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Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China by Fushui Liu, Ting Fang, Fanyuan Zhou, Meimei Zhao, Mei Chen, Jianyu You, Yuli Jin, Jinmei Xie, Zhongyong Liu

“…Compared with healthy control participants, the findings indicated that depression/anxiety symptoms were more common or severe in NP patients (respectively, SMD = 0.89; 95% CI = (0.58, 1.20); P<0.01 and SMD = 0.92; 95% CI = (0.65, 1.20); and P<0.01), results from the pooled data demonstrated no statistical significance between depression/anxiety symptoms and gender in NP patients (resp., SMD = 0.16; 95% CI = (−0.18, 0.51); P=0.35 and SMD = −0.08; 95% CI = (−0.42, 0.27); and P=0.67), and the combined data of the incidence of depression or anxiety symptoms revealed significant difference between NP patients and healthy persons (resp., RR = 4.81; 95% CI = (3.30, 7.01); P<0.01 and RR = 3.29; 95% CI = (2.16, 5.00); and P<0.01). …”
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The global, regional, and national patterns of change in the burden of bacterial pyoderma from 1990 to 2019 and the forecast for the next decade by Hao Wang, Zihao Bai, Chong Shen, Jiaxi Kou, Yanqing Zhu, Huaxia Xie, Chen Chen, Ran Mo

“…Abstract Pyoderma, commonly known as impetigo, is a bacterial skin infection causing pus formation, prevalent globally, especially in resource-poor areas. …”
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Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review by Boxuan Li, Shizhe Deng, Bomo Sang, Weiming Zhu, Bifang Zhuo, Menglong Zhang, Chenyang Qin, Yuanhao Lyu, Yuzheng Du, Zhihong Meng

“…Background. Aphasia is a common symptom in stroke patients, presenting with the impairment of spontaneous speech, repetition, naming, auditory comprehension, reading, and writing function. …”
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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…INCB001158 exposure was similar between groups (median, 56 days (monotherapy); 84 days (combination)). 49 patients (45.8%) on monotherapy and 76 (51.7%) on combination therapy experienced grade ≥3 treatment-emergent adverse events (AEs). The most common INCB001158-related AEs were fatigue (n=10/107 (9.3%)) and nausea (n=10/107 (9.3%)) with monotherapy and diarrhoea (n=24/147 (16.3%)) and fatigue (n=22/147 (15.0%)) with combination therapy. …”
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Primary repair vs arthroscopic reconstruction for proximal anterior cruciate ligament tears: a comparative study by Sergey A. Gerasimov, Ekaterina A. Morozova, Daria A. Naida, Denis O. Kolmakov, Andrey A. Zykin, Ekaterina V. Khramtsova

“…Type E of ACL injury prevailed in the sample. The most common associated injury in both cohorts was medial meniscus tear — 39.3±0.05% and 45.3±0.05% for Group1 and 2, relatively. …”
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How Reliable Is Endoscopic Scoring of Postoperative Recurrence in Crohn Disease?: A Systematic Review and Meta-Analysis by Eline M. L. van der Does de Willebois, MD, Vittoria Bellato, MD, Marjolijn Duijvestein, MD, PhD, Susan van Dieren, MD, PhD, Silvio Danese, MD, PhD, Pierpaolo Sileri, MD, PhD, Christianne J. Buskens, MD, PhD, Andrea Vignali, MD, PhD, Willem A. Bemelman, MD, PhD

“…This study aims to assess the variation in endoscopic recurrence (ER) rates in patients after ICR for CD using the most commonly used classification systems, the Rutgeerts score (RS) and modified Rutgeerts score (mRS) classifications. …”
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Value Propositions for Digital Shared Medication Plans to Boost Patient–Health Care Professional Partnerships: Co-Design Study by Benjamin Bugnon, Francesca Bosisio, Alain Kaufmann, Pascal Bonnabry, Antoine Geissbuhler, Christian von Plessen

“…Nevertheless, inaccurate medication lists and information gaps are common, particularly during care transitions, leading to avoidable harm, inefficiencies, and increased costs. …”
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Characterization of the complete genome sequence of the recombinant norovirus GII.P16/GII.4_Sydney_2012 revealed in Russia by E. V. Zhirakovskaia, A. Y. Tikunov, S. N. Sokolov, B. I. Kravchuk, E. I. Krasnova, N. V. Tikunova

“…Noroviruses (the Caliciviridae family) are a common cause of acute gastroenteritis in all age groups. …”
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both natural hosts and animal models of T. brucei infection. …”
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Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma by Liuyan Chen, Lvying Wu, Minying Tang, Yuanhang Cheng, Kuanyin Wang, Jianan Zhang, Wenyi Deng, Lingfeng Zhu, Jin Chen

“…Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common malignant urological tumor, and regrettably, and is insensitive to chemotherapy and radiotherapy, resulting in poor patient outcomes. …”
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