Real-world data of dacomitinib as first-line treatment for patients with EGFR-mutant non-small-cell lung cancer by Ji Eun Shin, Hyun Ae Jung, Sehhoon Park, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Byoung Yong Shim

“…Abstract Dacomitinib demonstrated superior survival benefit compared to gefitinib as a first-line treatment in non-small cell lung cancer (NSCLC) patients with common EGFR mutations through ARCHER 1050. However, there is limited real-world data concerning its efficacy and safety. …”
Get full text

Pharmacoeconomics and Utilisation of Antidiabetic Medications among Type 2 Diabetes Mellitus Patients: A Longitudinal Study by Bikash Chandra Das, P Ansuman Abhisek, Deepak Choudhury, Suvendu Kumar Panda, Jayanti Prava Behera, Supriya Pradhan, Trupti Rekha Swain, Sasmita Mallick

“…Metformin was the most commonly prescribed medication, both as a standalone therapy and in combination therapy. …”
Get full text

Microbial assisted alleviation of nickel toxicity in plants: A review by Xinyu Mao, Bilal Ahmad, Sabir Hussain, Farrukh Azeem, Muhammad Waseem, Yousef Alhaj Hamoud, Hiba Shaghaleh, Amany H.A. Abeed, Muhammad Rizwan, Jean Wan Hong Yong

“…Based on literature, the physicochemical methods are not commonly used due to their costly nature and the potential for producing secondary pollutants. …”
Get full text

Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study by Rahaf Hamdan BinHamdan, Salwa Abdulrahman Alsadhan, Arwa Zohair Gazzaz, AlBandary Hassan AlJameel

“…ResultsWhatsApp (n=344, 89.8%) and Instagram (n=304, 78.9%) were the most frequently used social media platforms daily. Common oral health misconceptions included beliefs that “Pregnancy causes calcium loss in teeth” (n=337, 87%) and “Dental treatment should be avoided during pregnancy” (n=245, 63.3%). …”
Get full text

The prevalence of sexual dysfunction and erectile dysfunction in men with multiple sclerosis: A systematic review and meta-analysis by V. Shaygannejad, O. Mirmosayyeb, S. Vaheb, N. Nehzat, M. Ghajarzadeh

“…Background: The prevalence of sexual dysfunction (SD) in men with multiple sclerosis (MS) is reported variously in different studies. The most common form of SD in these patients is erectile dysfunction (ED). …”
Get full text

UV-fs-LA-ICP-MS Analysis of CO2-Rich Fluid Inclusions in a Frozen State: Example from the Dahu Au-Mo Deposit, Xiaoqinling Region, Central China by Wei Jian, Moritz Albrecht, Bernd Lehmann, Jingwen Mao, Ingo Horn, Yanhe Li, Huishou Ye, Zongyan Li, Guanguan Fang, Yongsheng Xue

“…The recently developed technique of ultraviolet femtosecond laser ablation inductively coupled plasma mass spectrometry (UV-fs-LA-ICP-MS) combined with a freezing cell is expected to improve the analysis of CO2-rich fluid inclusions by decreasing their internal pressure and avoiding the common problem of uncontrolled explosive fluid release on ablation. …”
Get full text

WORLD EXPERIENCE IN ADMINISTRATIVE AND LEGAL SUPPORT OF FOOD SECURITY by Yuliya Pustovit, Olena Dragan, Alina Berher

“…However, all the countries analysed share the common goal of ensuring safe, high-quality and affordable food for their populations, while developing a sustainable agricultural sector. …”
Get full text

Echocardiography indicators in patients with atherosclerosis of peripheral arteries of the lower extremities dependent on T(–786)C polymorphism of the endothelial nitric oxide synt... by V.I. Tseluyko, O.D. Yarova

“…Systolic and diastolic dysfunction of the left ventricle myocardium were significantly more common in patients with coronary heart disease (p = 0.046; χ² = 3.95 and p = 0.02; χ² = 5.41 respectively). …”
Get full text

Transformers for Neuroimage Segmentation: Scoping Review by Maya Iratni, Amira Abdullah, Mariam Aldhaheri, Omar Elharrouss, Alaa Abd-alrazaq, Zahiriddin Rustamov, Nazar Zaki, Rafat Damseh

“…Half of all included studies were published in 2022, and more than two-thirds used transformers for segmenting brain tumors. The most common imaging modality was magnetic resonance imaging (n=59, 88.06%), while the most frequently used dataset was brain tumor segmentation dataset (n=39, 58.21%). 3D transformer models (n=42, 62.69%) were more prevalent than their 2D counterparts. …”
Get full text

SRT3025-loaded cell membrane hybrid liposomes (3025@ML) enhanced anti-tumor activity of Oxaliplatin via inhibiting pyruvate kinase M2 and fatty acid synthase by Xiaobin Wang, Shulin Li, Zichen Li, Zhuona Lin, Zhifeng Wang

“…Abstract Background Bladder cancer is one of the most common malignancies of the urinary system. Despite significant advances in diagnosis and treatment, the compromised therapeutic effect of chemotherapeutic agents, such as Oxaliplatin (OXA), remains a major clinical challenge. …”
Get full text

BananaImageBD: A comprehensive banana image dataset for classification of banana varieties and detection of ripeness stages in BangladeshMendeley Data by Md Hasanul Ferdaus, Rizvee Hassan Prito, Ahmed Abdal Shafi Rasel, Masud Ahmed, Md. Jahid Hassan Saykot, Shanjida Sultan Shanta, Sonali Akter, Ankan Chandra Das, Mohammad Manzurul Islam, Mahamudul Hasan, Md Sawkat Ali

“…The banana image dataset presented in this article includes clear and detailed images of four common banana varieties in Bangladesh: Sagor Kola (Musa acuminate), Shabri Kola (Musa sapientum), Bangla Kola (Musa sp.), and Champa Kola (Musa sapientum), as well as four key stages of banana ripeness: Green, Semi-ripe, Ripe, and Overripe. …”
Get full text

Phenotypic Identification of Blood Groups in Blood Donors: A Peruvian Multicenter Analysis by Yovera-Ancajima CDP, Calderon Cumpa LY, Lezama-Cotrina ID, Walttuoni-Picón E, Cárdenas-Mendoza WW, Culqui-García JE, Retuerto-Salazar WR, Céspedes Poma RC

“…It was also found that 1.5% of donors are carriers of the Kell antigen, all of which are clinically important.Conclusion: The phenotypic identification of blood groups in blood donors from three hospitals in Lima highlighted the clinical relevance of identifying less common antigens in the Kell, Kidd, Duffy, and MNS systems to prevent alloimmunization during blood transfusions.Keywords: alloimmunization, phenotype, blood group antigens, blood donors…”
Get full text

Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample by Catherine Prattico, Emmanuel Gonzalez, Lharbi Dridi, Shiva Jazestani, Kristin E. Low, D. Wade Abbott, Corinne F. Maurice, Bastien Castagner

“…Fructo-oligosaccharide (FOS) is a common diet-derived glycan that is fermented by the gut microbiota and has been used as a prebiotic. …”
Get full text

Optimizing Obstructive Sleep Apnea Risk Assessment in Hypertension: Development of a Predictive Nomogram in China by Yang Y, Sun X, Liang J, Liao WF, Ye W, Zheng Z, Du L, Chen M, Zhang Y, Lin W, Huang J, Yao W, Chen R

“…Yitian Yang,1,* Xishi Sun,2,* Jinhua Liang,1,* Wei Feng Liao,1,* Weilong Ye,1 Zhenzhen Zheng,1 Lianfang Du,1 Mingdi Chen,1 Yuan Zhang,3 Wenjia Lin,2 Jinyu Huang,2 Weimin Yao,1 Riken Chen1,4 1The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China; 2Emergency Medicine Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China; 3The First Clinical School of Medicine, Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China; 4State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, People’s Republic of China*These authors contributed equally to this workCorrespondence: Riken Chen; Weimin Yao, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China, Tel +13560244631 ; +13822521722, Email chenriken@126.com; 490296443@qq.comPurpose: Obstructive sleep apnea (OSA) is common in patients with hypertension. Our study aims to construct and validate an objective nomogram that can accurately predict the risk of OSA in patients with hypertension.Patients and Methods: Retrospective data were collected from patients with hypertension who underwent polysomnography (PSG) at the Sleep Medicine Center of the First Affiliated Hospital of Guangzhou Medical University, China. …”
Get full text

Effects of dietary selenium nanoparticles, selenomethionine and sodium selenite on growth performance, levels of thyroid hormones and antioxidant status of rainbow trout, Oncorhync... by Fardin Shaluei, Somayeh Hadadi, Shafigh Shafiei, Hossein Rahimi, Mehrdad Fattollahi

“…As for Se in the diet of fish, there are a few different forms commonly used as inorganic, such as Na2SeO3 or sodium selenite. …”
Get full text

Pregnancy Complications and Outcomes in Obese Women with Gestational Diabetes by Gitana Ramonienė, Laura Malakauskienė, Eglė Savukynė, Laima Maleckienė, Greta Gruzdaitė

“…Labour dystocia (<i>p</i> = 0.003) and foetal distress (<i>p</i> = 0,019) were more common during labour in obese women. Neonates of these women more often had macrosomia (<i>p</i> < 0.001) and lower Apgar scores at 1 min (<i>p</i> = 0.024) and at 5 min (<i>p</i> = 0.024) compared to neonates of normal-weight women. …”
Get full text

Delta Neutrophil Index in Coronary Artery Bypass Surgery: An Innovation in Postoperative Mortality Assessment by Bilgiç A, Toprak B, Kaya H

“…Traditional markers such as C-reactive protein (CRP) and white blood cell (WBC) counts are commonly used but have limitations in specificity and prognostic value. …”
Get full text

Co-Optimization of Operational and Intelligent Completion Parameters of CO₂ Water-Alternating-Gas Injection Processes in Carbonate Reservoirs by Xili Deng, Jingxuan Wang, Xiangguo Zhao, Liangyu Rao, Yongbin Zhao, Xiaofei Sun

“…During the use of MRC wells for CO₂ WAG injections, intelligent completions are commonly considered to control CO₂ breakthroughs. …”
Get full text

Adaptability of spring oat yield in the environments of the Near-Irtysh area in Omsk Province by P. N. Nikolaev, N. I. Aniskov, O. A. Yusova, I. V. Safonova

“…The aim of this work is to assess the adaptive potential of yield in spring oat cultivars developed at Omsk Agrarian Scientific Center in the environments of the Near-Irtysh area in Omsk Province, taking into account the most common statistical parameters. The object of the research were 9 spring oat cultivars recommended for cultivation in the region and undergoing the State Variety Trials: ‘Orion’ (reference), ‘Irtysh 13’, ‘Irtysh 21’, ‘Irtysh 23’, ‘Tarsky 2’, ‘Pamyati Bogachkova’, ‘Skakun’, ‘Fakel’ and ‘Sibirsky Gerkules’. …”
Get full text

After neonatal care, what next? A qualitative study of mothers’ post-discharge experiences after premature birth in Kenya by Justinah Maluni, Dorothy Oluoch, Sassy Molyneux, Mwanamvua Boga, Caroline Jones, Florence Murila, Mike English, Sue Ziebland, Lisa Hinton

“…Post-discharge mortality rates are high, and readmission is common. For mothers of premature babies, the transition home from hospital is marked by challenges and uncertainties. …”
Get full text