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41
Effects of Pesticides on Occupationally Exposed Humans
Published 2006-01-01“…In this study, we employed the Comet assay to examine DNA damage in peripheral blood lymphocytes (PBLs) from 64 greenhouse workers from Almería in south-eastern Spain in comparison to PBLs from 50 men from the same area but not engaged in any agricultural work. …”
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42
Perspectiva psicosocial en adolescentes acusados por delitos contra la salud y robo
Published 2009-01-01“…Nuestro objetivo en este estudio es identificar condiciones de vida de los sujetos adolescentes acusados de cometer delitos contra la salud y robo, desde una perspectiva psicosocial. …”
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43
Genotoxicity Studies of Titanium Dioxide Nanoparticles (TiO2NPs) in the Brain of Mice
Published 2016-01-01“…The present results report that exposure to TiO2NPs produces mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner. Moreover, Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of the Alzheimer’s disease. …”
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44
DNA Damage and Augmented Oxidative Stress in Bone Marrow Mononuclear Cells from Angiotensin-Dependent Hypertensive Mice
Published 2013-01-01“…The current study was performed to examine the effects of angiotensin-II-dependent hypertension in bone marrow mononuclear cells (BM-MNC); dihydroethidium staining was used to assess reactive oxygen species (ROS) production, and the comet assay was used to assess DNA fragmentation in 2K1C hypertensive mice 14 days after renal artery clipping. …”
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45
Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential
Published 2021-01-01“…A preliminary genotoxic potential was evaluated by the DNA comet assay test using C57Bl/6 mice. Both therapeutic dose (TD; 900 mg/kg) and high dose (HD; 9000 mg/kg) of UNCP were used. …”
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46
Insecticide chlorfenapyr confers induced toxicity in human cells through mitochondria-dependent pathways of apoptosis
Published 2025-01-01“…Chl's ability to induce DNA damage and apoptosis in human cells was confirmed through alkaline comet assay, immunofluorescence assay, and flow cytometric analysis. …”
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47
Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole
Published 2009-01-01“…The compounds are more active for base-pair substitution than frameshift induction in Salmonella; NFX and BNZ are more mutagenic than MTZ; they are widely dependent from nitroreduction whereas microsomal fraction S9 weakly affects the mutagenic potential. Comet assay detects BNZ- and NFX-induced DNA damage at doses in the range of therapeutically treated patient plasma concentration; BNZ seems to mainly act through ROS generation whereas a dose-dependent mechanism of DNA damaging is suggested for NFX. …”
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48
Exploring the Complex Heliotail Boundary by an Extended Level Set Approach
Published 2025-01-01“…Studies have shown that the heliotail may be “comet-like,” extending for thousands of au. Some previous works defined the heliopause using magnetohydrodynamic variables, which only serve as an approximation to capture the heliopause in all directions. …”
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49
Mapping the social-ecological suitability of agroforestry in the US Midwest
Published 2025-01-01“…We show that integrating social and economic factors dramatically shifted priorities compared to an environmental-only suitability assessment. Using COMET-Planner, we estimated that expanding agroforestry to the top 5% most suitable land from our analysis (totaling 18.3 million acres) has the potential to store 43 [29–58] Mt of CO _2 e per year over the business-as-usual scenario. …”
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50
Evaluación del riesgo y reincidencia en agresores sexuales sentenciados: implicaciones para las víctimas
Published 2010-01-01“…Debido, entonces, a la complejidad de los delitos, así como a la discusión acerca del equilibrio que requiere la reinserción para evitar la revictimización, en el presente documento se hace referencia a los perfiles empíricos descriptivos en muestras de población penitenciaria españolas y mexicanas, y su implicación en la reincidencia o riesgo victimal, enfatizando que el diagnóstico en el área criminológica es una herramienta fundamental que requiere de medios de evaluación específica, válida y confiable para tener aproximaciones reales acerca de la disposición de una persona a la hora de cometer conductas antisociales; relevante desde una perspectiva de política criminal, y con la finalidad del estudio psicológico del agresor, estudio que en última instancia apoyaría al tratamiento penitenciario y a la prevención del delito.…”
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51
Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study
Published 2014-01-01“…The aim of our study was to compare the radiosensitivity and induction of apoptosis by high LET 12C and low LET gamma radiation in HeLa and PARP-1 knocked down cells. We did comet assay to detect DNA breaks, clonogenic survival assay, and cell cycle analysis to measure recovery after DNA damage. …”
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52
Errores en la preparación y administración de medicamentos en los profesionales de enfermería de un hospital nivel II-2 de Chiclayo
Published 2024-11-01“…Por lo que se pudo identificar que hay un buen porcentaje que comete errores en la administración y un mínimo en la preparación de medicamentos. …”
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53
Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
Published 2022-01-01“…The cytotoxicity profiles of AgNPs-GA were characterized by MTT assay, intracellular reactive oxygen species (ROS) assay, and DAPI and AOPI double staining, whilst genotoxicity was assessed using Comet Assay analysis. The level of silver ions (Ag+) and cellular uptake of AgNPs-GA were evaluated by ICP-OES and TEM analyses, respectively. …”
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54
Constituição e processo penal
Published 2023-05-01“…Os sistemas processuais penais e os princípios processuais penais com ênfase na Constituição Federal garantem o Estado Democrático de Direitos no qual o sujeito, acusado de cometer um ilícito penal, tem o direito de ser julgado com garantias constitucionais que validam a aplicação da pena e todo o processo. …”
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55
Análisis preliminar de un protocolo para la evaluación de marcos deícticos
Published 2013-01-01“…En todos los grupos de edad se halló una tendencia a cometer mayor cantidad de errores en la versión computarizada en todos los tipos de ensayo. …”
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56
Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes
Published 2022-01-01“…After 24 hours of treatment, we conducted a cytokinesis-Block micronucleus test and an alkaline comet assay in order to determine genetic damage. …”
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57
Salud y autocuidado en madres de niños con hemofilia: estudio de casos
Published 2011-12-01“…La maternidad para estas mujeres demanda un grado de perfección y de exigencia muy alto, porque la hemofilia se percibe como un “fracaso propio” de ellas como mujeres y madres y parece implicar que no es posible cometer más errores. Esta exigencia conlleva un alto nivel de sacrificio personal para estas mujeres lo cual repercute en su salud y se manifiesta de diferentes maneras como carencia de redes de apoyo, con estilos de vida sedentarios, depresión y enfermedades crónicas. …”
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RETRACTED: Efficacy of Vanadyl Sulfate and Selenium Tetrachloride as Anti-Diabetic Agents against Hyperglycemia and Oxidative Stress Induced by Diabetes Mellitus in Male Rats
Published 2021-12-01“…The test subjects’ blood glucose, insulin hormone, HbA1C, C-peptide, antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, myeloperoxidase, and xanthine oxidase), markers of lipid peroxidation (MDA), and histological sections of pancreatic tissues were evaluated, and a comet assay was performed. Histological sections in pancreas tissues were treated as indicators of both VOSO<sub>4</sub> and selenium tetrachloride efficacy, either alone or combined, for the alleviation of STZ toxicity. …”
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Anticancer activity of Ilex khasiana, a rare and endemic species of holly in Northeast India, against murine lymphoma
Published 2025-01-01“…On the other hand, glutathione level, glutathione S-transferase and superoxide dismutase activity increased. Alkaline comet assay showed that the plant extract effectively induced DNA damage, producing a tail length of 11.89 μm and Olive moment of 2.36 at 250 mg/kg bwt, the most effective dosage. …”
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60
Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita
Published 2025-02-01“…Oxidative stress parameters; ROS and TBARS were increased significantly (p < 0.05) while antioxidant enzymes (CAT, SOD, POD, GSH) showed a significant (p < 0.05) decrease in the treated groups compared to the control. Moreover, comet assay revealed significant (p < 0.05) DNA damage in the isolated cells of kidneys, heart and brain at higher doses (80 μg/L and 120 μg/L) of thiram that was further confirmed by histo-pathological alterations in these tissues. …”
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