Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey by Anton F Engelsman, Romana T Netea-Maier, Christiaan F Mooij, Robin P Peeters, Menno R Vriens, A S Paul van Trotsenburg, Schelto Kruijff, Joep P M Derikx, Faridi S Jamaludin, Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Eveline Bruinstroop, Frederik A Verburg, Angelique Seur, Els J M Nieveen van Dijkum

“…The study is registered in the COMET initiative database (registration number 2597). …”
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Genotoxicity Studies of Titanium Dioxide Nanoparticles (TiO2NPs) in the Brain of Mice by Hanan R. H. Mohamed, Nahed A. Hussien

“…The present results report that exposure to TiO2NPs produces mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner. Moreover, Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of the Alzheimer’s disease. …”
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Genotoxicity Biomarkers Study in Agricultural Workers Exposed to Pesticides: a Systematic Review by Edisson Vladimir Maldonado Mariño, Darío Orlando Siza Saquinga, Diego Eduardo Guato Canchinia, Alexander Javier Ramos Velastegui

“…Among the most commonly used biomarkers to determine the impact are: the comet assay and the cytokinesis blocking micronucleus assay, in addition, some specific ones at the genetic level were used, such as the polymerase chain reaction. …”
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Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse by Bianca P. Campagnaro, Agata L. Gava, Silvana S. Meyrelles, Elisardo C. Vasquez

“…We show recent data from the angiotensin-dependent hypertensive mouse demonstrating DNA damage and oxidative stress using the comet assay and flow cytometry, respectively. Finally, we highlight the relationships between angiotensin and peripheral and central nervous system areas of cardiovascular control and oxidative stress in the 2K1C hypertensive mouse.…”
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Evaluation of Genotoxic and Cytotoxic Effects in Human Peripheral Blood Lymphocytes Exposed In Vitro to Neonicotinoid Insecticides News by María Elena Calderón-Segura, Sandra Gómez-Arroyo, Rafael Villalobos-Pietrini, Carmen Martínez-Valenzuela, Yolanda Carbajal-López, María del Carmen Calderón-Ezquerro, Josefina Cortés-Eslava, Rocío García-Martínez, Diana Flores-Ramírez, María Isabel Rodríguez-Romero, Patricia Méndez-Pérez, Enrique Bañuelos-Ruíz

“…The genotoxic and cytotoxic effects were evaluated using the alkaline comet and trypan blue dye exclusion assays. DNA damage was evaluated using two genotoxicity parameters: tail length and comet frequency. …”
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Impact of SWCNT-conjugated senna leaf extract on breast cancer cells: A potential apoptotic therapeutic strategy by Behairy Sabreen Mohammed, Al-Maaqar Saleh Mohammed, Al-Shaeri Majed Ahmed

“…Cell viability was assessed using the MTT assay, while Giemsa staining revealed morphological changes. Additionally, the comet assay and agarose gel electrophoresis were employed to evaluate the pro-apoptotic potential. …”
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Analysis of Land Displacement Utilizing Sentinel-1 Satellite Imagery and InSAR Technique: A Case Study in Kern County, California by Javad Hatamiafkoueieh

“…A time-series analysis was performed to examine the temporal evolution of land displacement using the Small Baseline Subset (SBAS-InSAR) approach. The LicSAR (Comet Portal) and Liscbas toolbox were employed to analyze Sentinel-1 satellite data collected between 2014 and 2022. …”
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Effects of Pesticides on Occupationally Exposed Humans by Stylianos M. Piperakis, Konstantina Kontogianni, Michael M. Piperakis, Ricardo Marcos, Smaragdi Tsilimigaki

“…In this study, we employed the Comet assay to examine DNA damage in peripheral blood lymphocytes (PBLs) from 64 greenhouse workers from Almería in south-eastern Spain in comparison to PBLs from 50 men from the same area but not engaged in any agricultural work. …”
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Mapping the social-ecological suitability of agroforestry in the US Midwest by Sarah E Castle, Daniel C Miller, Chloe B Wardropper

“…We show that integrating social and economic factors dramatically shifted priorities compared to an environmental-only suitability assessment. Using COMET-Planner, we estimated that expanding agroforestry to the top 5% most suitable land from our analysis (totaling 18.3 million acres) has the potential to store 43 [29–58] Mt of CO _2 e per year over the business-as-usual scenario. …”
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Gama Radyasyonun İndüklediği Nefrotoksiteye Karşılık Pycnogenolün Koruyucu Etkisi by Oğuz Galip Yıldız, Güler Toprak, Arzu Hanım Yay, Fazile Cantürk Tan

“…Kontrole göre diğer gruplarda comet parametreleri artmış, bu parametreler antioksidan + radyasyon gruplarda radyasyon grubuna göre azalmıştı p…”
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Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study by Atanu Ghorai, Nitai P. Bhattacharyya, Asitikantha Sarma, Utpal Ghosh

“…The aim of our study was to compare the radiosensitivity and induction of apoptosis by high LET 12C and low LET gamma radiation in HeLa and PARP-1 knocked down cells. We did comet assay to detect DNA breaks, clonogenic survival assay, and cell cycle analysis to measure recovery after DNA damage. …”
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Implications of high-resolution velocity and strain rate observations for modelling of Greenlandic tidewater glaciers by Dominik Fahrner, Pablo J. González, Douglas W. F. Mair, James M. Lea

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Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines by Musthahimah Muhamad, Nurhidayah Ab.Rahim, Wan Adnan Wan Omar, Nik Nur Syazni Nik Mohamed Kamal

“…The cytotoxicity profiles of AgNPs-GA were characterized by MTT assay, intracellular reactive oxygen species (ROS) assay, and DAPI and AOPI double staining, whilst genotoxicity was assessed using Comet Assay analysis. The level of silver ions (Ag+) and cellular uptake of AgNPs-GA were evaluated by ICP-OES and TEM analyses, respectively. …”
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Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes by Ehsan Zamani, Alireza Ahmadi Shad, Hediye Fatemi, Saba Mahboubi, Azadeh Motavallian, Mehdi Evazalipour

“…After 24 hours of treatment, we conducted a cytokinesis-Block micronucleus test and an alkaline comet assay in order to determine genetic damage. …”
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ALMA Spectral Survey of an Eruptive Young Star, V883 Ori (ASSAY). II. Freshly Sublimated Complex Organic Molecules in the Keplerian Disk by Jae-Hong Jeong, Jeong-Eun Lee, Seonjae Lee, Giseon Baek, Ji-Hyun Kang, Seokho Lee, Chul-Hwan Kim, Hyeong-Sik Yun, Yuri Aikawa, Gregory J. Herczeg, Doug Johnstone, Lucas Cieza

“…In addition, as found in the comet 67P/Churyumov-Gerasimenko, nitrogen might also be trapped as ammonium salt within the dust grains in the V883 Ori disk.…”
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Radioprotective Effect of Alk(en)yl Thiosulfates Derived from Allium Vegetables against DNA Damage Caused by X-Ray Irradiation in Cultured Cells: Antiradiation Potential of Onions... by Hye-Sook Chang, Daiji Endoh, Yushi Ishida, Hiroyuki Takahashi, Shuji Ozawa, Masanobu Hayashi, Akira Yabuki, Osamu Yamato

“…Cell damage caused by the irradiation was quantified as comet tail moment, which represents the degree of DNA damage. …”
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Exploring the Complex Heliotail Boundary by an Extended Level Set Approach by C. Onubogu, M. Opher, M. Kornbleuth, G. Tóth, V. Florinski

“…Studies have shown that the heliotail may be “comet-like,” extending for thousands of au. Some previous works defined the heliopause using magnetohydrodynamic variables, which only serve as an approximation to capture the heliopause in all directions. …”
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DNA Damage and Augmented Oxidative Stress in Bone Marrow Mononuclear Cells from Angiotensin-Dependent Hypertensive Mice by Bianca P. Campagnaro, Clarissa L. Tonini, Breno V. Nogueira, Dulce E. Casarini, Elisardo C. Vasquez, Silvana S. Meyrelles

“…The current study was performed to examine the effects of angiotensin-II-dependent hypertension in bone marrow mononuclear cells (BM-MNC); dihydroethidium staining was used to assess reactive oxygen species (ROS) production, and the comet assay was used to assess DNA fragmentation in 2K1C hypertensive mice 14 days after renal artery clipping. …”
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Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human l... by Nathaniel Lee, Chris Smith, Robin Bailey, Koya Ariyoshi, Sarah Smith, Nick Black, Tansy Edwards

“…Methods The COS-LEP study will employ a COS development methodology standardized by the COMET initiative framework. This includes (1) a systematic review of available quantitative and qualitative literature reporting therapeutic response and safety outcomes and measures; (2) focused interviews with healthcare professional and people treated for leptospirosis exploring outcomes of interests using qualitative methodology; (3) narrowing the choice of outcomes by international consensus using a Delphi survey process; and (4) undertaking a hybrid consensus meeting with key stakeholders to build the final COS. …”
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RETRACTED: Efficacy of Vanadyl Sulfate and Selenium Tetrachloride as Anti-Diabetic Agents against Hyperglycemia and Oxidative Stress Induced by Diabetes Mellitus in Male Rats by Fawziah A. Al-Salmi, Reham Z. Hamza

“…The test subjects’ blood glucose, insulin hormone, HbA1C, C-peptide, antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, myeloperoxidase, and xanthine oxidase), markers of lipid peroxidation (MDA), and histological sections of pancreatic tissues were evaluated, and a comet assay was performed. Histological sections in pancreas tissues were treated as indicators of both VOSO₄ and selenium tetrachloride efficacy, either alone or combined, for the alleviation of STZ toxicity. …”
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