-
21
Identification of a Multicriteria Decision-Making Model Using the Characteristic Objects Method
Published 2014-01-01“…This paper presents a new, nonlinear, multicriteria, decision-making method: the characteristic objects (COMET). This approach, which can be characterized as a fuzzy reference model, determines a measurement standard for decision-making problems. …”
Get full text
Article -
22
Cellular Reference Materials for DNA Damage Using Electrochemical Oxidation
Published 2020-01-01“…Reference materials are needed to quantify the level of DNA damage in cells, to assess sources of measurement variability and to compare results from different laboratories. The comet assay (single cell gel electrophoresis) is a widely used method to determine DNA damage in the form of strand breaks. …”
Get full text
Article -
23
Evaluation of the cytogenetic and genotoxic effects of an abamectin-based pesticide on Allium cepa roots
Published 2024-01-01“…Chromosomal aberration (CA) frequencies in the dividing cells and comet data were used for genotoxicity assessment. …”
Get full text
Article -
24
Young Cuban Patients with a Clinical and biochemical Diagnosis of Xeroderma Pigmentosum
Published 2024-08-01“…<strong>Foundation:</strong> skin cancer is a complication of xeroderma pigmentosum; early diagnosis is important. The alkaline comet assay with ultraviolet C radiation and the western blot assay are useful for diagnosis. …”
Get full text
Article -
25
Genotoxic Potential and Physicochemical Parameters of Sinos River, Southern Brazil
Published 2013-01-01“…The present study aimed to evaluate the physicochemical parameters and the genotoxic potential of water samples collected in the upper, middle, and lower courses of the Sinos River, southern Brazil. The comet assay was performed in the peripheral blood of fish Hyphessobrycon luetkenii exposed under laboratory conditions to water samples collected in summer and winter in three sampling sites of Sinos River. …”
Get full text
Article -
26
Cytotoxicity and genotoxicity of orthodontic bands after aging: an in-vitro study
Published 2025-01-01“…Regarding genotoxicity, DNA damage was evident for both brands at pH = 4.5, however, AO molar bands demonstrated longer comet tails compared to 3 S-dental molar bands. AO molar bands was also showed relatively DNA destruction at pH 7.4, while no genotoxicity was for 3 S-dental molar bands. …”
Get full text
Article -
27
-
28
Grand canyons on the Moon
Published 2025-02-01“…Here we use photogeologic mapping of those canyons and related impact ejecta deposits to show the trajectory of the impacting asteroid or comet, which produced an asymmetrical pattern of crater excavation and transport of ejected debris. …”
Get full text
Article -
29
Genotoxicity Studies of Titanium Dioxide Nanoparticles (TiO2NPs) in the Brain of Mice
Published 2016-01-01“…The present results report that exposure to TiO2NPs produces mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner. Moreover, Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of the Alzheimer’s disease. …”
Get full text
Article -
30
Genotoxicity Biomarkers Study in Agricultural Workers Exposed to Pesticides: a Systematic Review
Published 2024-11-01“…Among the most commonly used biomarkers to determine the impact are: the comet assay and the cytokinesis blocking micronucleus assay, in addition, some specific ones at the genetic level were used, such as the polymerase chain reaction. …”
Get full text
Article -
31
Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse
Published 2012-01-01“…We show recent data from the angiotensin-dependent hypertensive mouse demonstrating DNA damage and oxidative stress using the comet assay and flow cytometry, respectively. Finally, we highlight the relationships between angiotensin and peripheral and central nervous system areas of cardiovascular control and oxidative stress in the 2K1C hypertensive mouse.…”
Get full text
Article -
32
Evaluation of Genotoxic and Cytotoxic Effects in Human Peripheral Blood Lymphocytes Exposed In Vitro to Neonicotinoid Insecticides News
Published 2012-01-01“…The genotoxic and cytotoxic effects were evaluated using the alkaline comet and trypan blue dye exclusion assays. DNA damage was evaluated using two genotoxicity parameters: tail length and comet frequency. …”
Get full text
Article -
33
Effects of Pesticides on Occupationally Exposed Humans
Published 2006-01-01“…In this study, we employed the Comet assay to examine DNA damage in peripheral blood lymphocytes (PBLs) from 64 greenhouse workers from Almería in south-eastern Spain in comparison to PBLs from 50 men from the same area but not engaged in any agricultural work. …”
Get full text
Article -
34
Mapping the social-ecological suitability of agroforestry in the US Midwest
Published 2025-01-01“…We show that integrating social and economic factors dramatically shifted priorities compared to an environmental-only suitability assessment. Using COMET-Planner, we estimated that expanding agroforestry to the top 5% most suitable land from our analysis (totaling 18.3 million acres) has the potential to store 43 [29–58] Mt of CO _2 e per year over the business-as-usual scenario. …”
Get full text
Article -
35
Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study
Published 2014-01-01“…The aim of our study was to compare the radiosensitivity and induction of apoptosis by high LET 12C and low LET gamma radiation in HeLa and PARP-1 knocked down cells. We did comet assay to detect DNA breaks, clonogenic survival assay, and cell cycle analysis to measure recovery after DNA damage. …”
Get full text
Article -
36
Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
Published 2022-01-01“…The cytotoxicity profiles of AgNPs-GA were characterized by MTT assay, intracellular reactive oxygen species (ROS) assay, and DAPI and AOPI double staining, whilst genotoxicity was assessed using Comet Assay analysis. The level of silver ions (Ag+) and cellular uptake of AgNPs-GA were evaluated by ICP-OES and TEM analyses, respectively. …”
Get full text
Article -
37
Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes
Published 2022-01-01“…After 24 hours of treatment, we conducted a cytokinesis-Block micronucleus test and an alkaline comet assay in order to determine genetic damage. …”
Get full text
Article -
38
Radioprotective Effect of Alk(en)yl Thiosulfates Derived from Allium Vegetables against DNA Damage Caused by X-Ray Irradiation in Cultured Cells: Antiradiation Potential of Onions...
Published 2012-01-01“…Cell damage caused by the irradiation was quantified as comet tail moment, which represents the degree of DNA damage. …”
Get full text
Article -
39
Exploring the Complex Heliotail Boundary by an Extended Level Set Approach
Published 2025-01-01“…Studies have shown that the heliotail may be “comet-like,” extending for thousands of au. Some previous works defined the heliopause using magnetohydrodynamic variables, which only serve as an approximation to capture the heliopause in all directions. …”
Get full text
Article -
40
DNA Damage and Augmented Oxidative Stress in Bone Marrow Mononuclear Cells from Angiotensin-Dependent Hypertensive Mice
Published 2013-01-01“…The current study was performed to examine the effects of angiotensin-II-dependent hypertension in bone marrow mononuclear cells (BM-MNC); dihydroethidium staining was used to assess reactive oxygen species (ROS) production, and the comet assay was used to assess DNA fragmentation in 2K1C hypertensive mice 14 days after renal artery clipping. …”
Get full text
Article